House vacation rentals in Mesa County
Find and book unique houses on Airbnb
Top-rated house rentals in Mesa County
Guests agree: these houses are highly rated for location, cleanliness, and more.
Vacation rentals for every style
Get the amount of space that is right for you
Popular amenities for Mesa County house rentals
House rentals with a pool
Home in Palisade
4.83 out of 5 average rating, 41 reviewsPeach Orchard Dreamy Farmhouse w/Pool & Hot Tub
Jan 17 – 24
Home in Clifton
4.96 out of 5 average rating, 57 reviewsBlue Skies Casita @ Palisade Legends
Feb 21 – 28
Home in Palisade
5.0 out of 5 average rating, 13 reviewsBrand New Listing - The Mesa ViewHouse!
Aug 9 – 16
Home in Grand Junction
5.0 out of 5 average rating, 53 reviewsPool, hot tub, views and close to everything
Apr 4 – 11
Home in Grand Junction
4.78 out of 5 average rating, 27 reviewsAdventure Home Base - 7 Blocks to Downtown!
Aug 24 – 31
Home in Grand Junction
4.95 out of 5 average rating, 20 reviewsGreat Location, Large Home with Indoor Pool & more
Jun 23 – 30
Home in Grand Junction
5.0 out of 5 average rating, 22 reviewsThe Painted Lady Estate
Mar 23 – 30
Home in Grand Junction
4.82 out of 5 average rating, 51 reviewsCozy lake house, great location
Apr 3 – 10
Weekly house rentals
Home in Grand Junction
4.94 out of 5 average rating, 133 reviewsFamily friendly, quiet & comfy 3BR home North area
Jul 13 – 20
Home in Fruita
4.94 out of 5 average rating, 127 reviewsReinvigorate in our charming house on Main Street
Oct 21 – 28
Home in Grand Junction
4.97 out of 5 average rating, 170 reviewsDowntown Launchpad for your Colorado Adventures!
Mar 31 – Apr 7
Home in Grand Junction
4.84 out of 5 average rating, 142 reviewsMonumental Memories
Jan 29 – Feb 5
Home in Grand Junction
4.99 out of 5 average rating, 141 reviewsBlue Door Farm Vacation Rental
Dec 26 – Jan 2
Home in Fruita
4.91 out of 5 average rating, 180 reviewsF-Town Central - Shady Oasis in Heart of Fruita
Jun 24 – Jul 1
Home in Fruita
4.91 out of 5 average rating, 206 reviewsStay at one of Airbnb's Most Adored Homes!
Mar 27 – Apr 3
Home in Grand Junction
4.85 out of 5 average rating, 654 reviewsHappy Hippie House
Oct 1 – 8
Private house rentals
Home in Hotchkiss
4.95 out of 5 average rating, 149 reviewsThe Moon House. Come mingle with the stars.
Dec 19 – 26
Home in Paonia
4.82 out of 5 average rating, 155 reviews3rd Street Artists Retreat
Aug 27 – Sep 3
Home in Palisade
4.96 out of 5 average rating, 195 reviewsStay at The View House
Jun 20 – 27
Home in Grand Junction
4.94 out of 5 average rating, 112 reviewsCasa Rio. The Bright Cozy home across the river
Jan 6 – 13
Home in Grand Junction
4.94 out of 5 average rating, 188 reviewsViews+, Ski/Hike/Golf/Hot Tub, CO Nat'l Monument!
Apr 2 – 9
Home in Grand Junction
4.94 out of 5 average rating, 105 reviewsNew, Clean & Cheerful Townhome
Jan 11 – 18
Home in Paonia
4.96 out of 5 average rating, 113 reviewsComfy country home with mountain views.
Oct 8 – 15
Home in Grand Junction
4.96 out of 5 average rating, 81 reviewsCharming GJ Downtowner
Sep 12 – 19
Destinations to explore
- Earth house rentals United States
- Guesthouse rentals United States
- House rentals United States
- Townhouse rentals United States
- Lighthouse rentals United States
- Tiny house rentals Colorado
- Townhouse rentals Colorado
- Guesthouse rentals Colorado
- House rentals Colorado
- Lakehouse rentals Colorado
- Earth house rentals Colorado
- Townhouse rentals Aspen
- House rentals Aspen
- Townhouse rentals Moab
- House rentals Moab
- House rentals Telluride
- Townhouse rentals Telluride
- Cabin rentals Mesa County
- Family-friendly rentals Mesa County
- Rentals with lake access Mesa County
- Apartment rentals Mesa County
- Condo rentals Mesa County
- Rentals with a kayak Mesa County
- Rentals with a fire pit Mesa County
- Rentals with a hot tub Mesa County
- Pet-friendly rentals Mesa County
- Kid-friendly rentals Mesa County
- Tiny house rentals Mesa County
- Bed and breakfasts Mesa County
- Farmstay rentals Mesa County
- Rentals with a fireplace Mesa County
- Rentals with pools Mesa County
- Rentals with a patio Mesa County
- Rentals with breakfast Mesa County
- Monthly Rentals Mesa County
- Rentals with a washer and dryer Mesa County
- Private suite rentals Mesa County
- Rentals with outdoor seating Mesa County
- Yurt Rentals United States
- Yurt Rentals United Kingdom
- Castle Rentals United States
- Houseboats United States
- Holiday Caravans United Kingdom
- Private Island Rentals United States
- Farm Houses United States
- Farm Cottages United Kingdom
- Cabin Rentals Australia
- Luxury Cabins United Kingdom
- Luxury Cabins United States
- Holiday Chalets United Kingdom
- Cottage Rentals United States
- Holiday Cottages United Kingdom
- Mansion Rentals United States
- Villa Rentals United Kingdom
- Holiday Bungalows United Kingdom
- Bungalow Rentals United States
- Condo Rentals United States
- Holiday Apartments Australia
- Holiday Houses United States
- Holiday Houses United Kingdom
- Private Holiday Rentals United Kingdom
- Big House Rentals United States
- Big Cottages Australia
- Large Villas United Kingdom
- House Rentals with a Pool United States
- Cabin Rentals with a Pool United States
- Villas with a Pool United Kingdom
- Apartments with a Hot Tub United States
- Holiday Cottages with a Hot Tub United Kingdom
- Beach Cabins United States
- Beach Condos United States
- Beachfront Rentals United States
- Beach Houses United Kingdom
- Beach Villas United Kingdom
- Coastal Cottages United Kingdom
- Pet-Friendly Vacation Rentals United States
- Pet-Friendly Beach Rentals United States
- Pet-Friendly Cabin Rentals United States
- Dog-Friendly Cottages United Kingdom
- Luxury Dog-Friendly Cottages United Kingdom