
House vacation rentals in Mesa County
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Top-rated house rentals in Mesa County
Guests agree: these houses are highly rated for location, cleanliness, and more.
Vacation rentals for every style
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Popular amenities for Mesa County house rentals
House rentals with a pool

Hot Tub~Pool~Tiki Bar~Game Room~Mini Golf~Fire Pit
We had an amazing time at Alex’s Airbnb! The house was clean, inviting and unique! We chose his place because of all the fun amenities and the unique vibe. Don’t settle for a basic house or a hotel. His place is where you want to stay when visiting Grand Junction or Palisade. There was so much to do! We celebrated my aunt’s 50th birthday and took her to some wineries in Palisade (which is only a 15 minute drive.) However, we spent the majority of our trip hanging out at the house enjoying the pool, tiki bar, hot tub, game room and fire pit. We would highly recommend to anyone looking to have a fun and exciting time with their family and friends. We didn’t have any issues, but Alex was very responsive to any of our questions. Thanks Alex!

Pool, hot tub, views and close to everything
The house is as advertised. Beautiful vistas, yard, pool, room for 14 people. If you think you might need or want, bring your own washcloths and dishtowels as only a few of each were provided. It was great they had a bin of pool towels outside to use. Maria was very responsive when we had questions. I would certainly book here again.

Large home,Multi family, Near CMU&Airport
It was a perfect spot for 2 families to share! Very family friendly and the most beautiful backyard.

Palisade Peach Orchard Farmhouse w/Pool & Spa 18+
Great spot. We enjoyed the views and ample amenities around the house. Peaceful and private, yet close to town.

The Honey Bee @ Palisade Legends
Great little place! We stayed for 3 nights and this had everything we needed and more. Thank you!

Rustic Refuge - minutes from downtown Fruita
Our stay was great! It's a clean place and had everything we needed. The backyard was awesome, although we didn't get to enjoy it because our schedule was packed. Andre is a great host!

Adventure Home Base - 7 Blocks to Downtown!
we enjoyed our stay. We had all the amenities we could need. The place was very spacious, and the backyard was a huge plus. it was close to everything and very quiet/peaceful. we would stay here again.

Lakeside Retro 4BR 2 BA, Pool, Hot Tub whole house
We loved it!!! Brad and Sarah are great host when we needed something they responded promptly and were always friendly I definitely recommend this place, it’s cozy loved the decoration and beds were really comfortable the whole home was very clean.. thank you Brad and Sarah for having us and when we go to Colorado I’ll definitely be looking forward to staying there again❤️👌
Weekly house rentals

Peach Chalet, views, quiet, 5 min to downtown
Absolutely Exceptional — A Stay We'll Never Forget. We chose Jennifer’s Peach Chalet while traveling for my sister’s celebration of life. I was especially drawn to her listing because it mentioned a hummingbird feeder — a meaningful detail, as the hummingbird is my sister’s spirit animal. What we experienced went far beyond expectations. Jennifer left a thoughtful card and a beautiful hummingbird gift for us — a gesture so kind and unexpected, it brought us to tears. Her compassion in such a delicate moment meant the world to us. As for the chalet itself — it was flawless. Immaculately clean, beautifully decorated, and thoughtfully designed with little details like labeled light switches that made our stay effortless. The views are breathtaking, and the photos truly don’t capture how special this place is. Despite the somber reason for our trip, Jennifer’s home provided the peace and comfort we so deeply needed. It is, without question, one of the best properties we’ve ever stayed in.

420Friendly_HotTub_12kGameArcade_WineBar_5Bed
Can't say enough positives about Vincent and this place. Property is awesome and exactly as advertised. Vincent was helpful and really delivered a great experience. I can't wait to stay here again next time I'm in Grand Junction

Fully Stocked 3 BR HOME - Work & Play w/fast WiFi
It was my wedding week, and I decided to go back to my hometown to get married. I had family on from all over the country and we all stayed together at this wonderful place. very accommodating, comfortable, easy to get to, clean, and much more. We had more than we needed or wanted and many fond memories were made here. This will forever be a special place to me. I can't thank the wonderful hosts enough for having such a fantastic place for us all to land.

The Centennial House ~ Historic 6BR, 3BA home.
We thoroughly enjoyed our stay. This house has every extra touch you could ever ask for. The location and amenities were excellent. We will definitely stay again.

Walkable Downtown Historic Home: A/C, Patios, BBQ
Perfect for our family rendezvous! Beds were very comfortable!!

Quiet and cozy home away from home with hot tub.
Great location and responsive host. Would stay here again.

Monument Paradise on golf course
Very cute home with an amazing location on the golf course looking out at the National Monument. Comfortable beds and great space to celebrate our daughters college graduation

Family friendly, quiet & comfy 3BR home North area
We had the perfect stay at Nigel’s place. The cleanliness is immaculate! Home felt so cozy and inviting. Everything is well stocked with lots of thoughtful extras. We enjoyed the board games. The screened in porch was a wonderful place to relax. The beds are all so comfortable. Loved the convenience of parking in the garage too. Very beautiful, quiet neighborhood. We would definitely rent this home again.
Private house rentals

Modern Cozy Mountain Home at Powderhorn—Amenities!
Perfect location for multi family, multi location reunion as it was just down the street from two of our other homes. Sledding hill was a plus for the non-skiers @ the house. Host response tremendously timely & helpful. Accomodations very comfortable for everyone & appreciated the ample amount of amenities, especially the generous amount of Keurig cups. Overall made our family reunion stellar!

3 Blcks to DT / Fam-Friendly / W&D / Full Kitchen
Can walk to town for breakfast or shopping. Kitchen had everything you could need and had a good work area. The desk had pencils and pens and scissors and tape and things you need but don't frequently find in an Air B&B. Quiet neighborhood and pleasant home.

Luxury Home/ Hot Tub
Great place to stay! Very spacious and everyone had their own space. They had a nice game area and backyard that we didn’t have time to enjoy but nice. Matched the descriptions

Mesa Creek Cottage
This was a beautiful stay. Definitely felt like home away from home. It was nice to get up and drink a cup of coffee and see the deer through the window. At night enjoy one can enjoy a nice evening outside and cuddled up with a blanket by the fire. My family and I came down for our neice College Graduation in Grand Junction which is only a 32 min drive. While the rest of the family stood in hotels we had the best experience staying at Thomas place. What I loved the most is that they had more that what traditional AirBnB offers. Thank you for being amazing host and quick with responses. We will definitely stay here again when we come back!

GJ Wine & Hot Tub Retreat
Great Airbnb right in the middle of downtown Grand Junction and Palisade! We enjoyed the shopping and restaurants in GJ and the fruit stands, wineries, and hiking in Palisade. The Airbnb had comfortable accommodations, wonderful sheets/towels, and tons of room for our girls trip. We would definitely come back here again!

Love Orchard
Wow! If you are ever in Palisade this is an amazing place. We came for the Bluegrass Concert and wanted to stay forever. Krisit was such a great host. Highly recommended.

The House on Pioneer
Only thing different was the fact that he stayed downstairs in a basement living quarters, other than that it was great

Explorer Hideaway
We loved Micah’s place by lunch loops. Super convenient to trails and town. The house is clean and has everything we wanted inside. Thanks!
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