Vacation rentals in Mesa County

Find and book unique accommodations on Airbnb

Top-rated vacation rentals in Mesa County

Guests agree: these stays are highly rated for location, cleanliness, and more.

0 of 0 items showing

1 of 3 pages

Guest favorite

An outdoor seating area is presented with four chairs arranged around a fire pit. A tall table with chairs stands in the background, adjacent to a pink door. A staircase leads to the upper level, and greenery is visible in the surrounding space.

Guesthouse in Grand Junction

4.94 out of 5 average rating, 360 reviews

GJ Rafters on Rood - Downtown Location!

Enjoy a stylish experience at this centrally-located spot. BRAND NEW CONSTRUCTION just blocks away from downtown Grand Junction. Rafters on Rood welcomes you with a fire pit area equipped with an outdoor eating space as well as a grill. Stepping inside the space you will find two Smart TVs, a comfortable living room area as well as a fashionable kitchen. Top of the line mattresses greet you in each bedroom as well as vaulted ceilings and high end finishes throughout. LOCATION is key! CENTRAL AIR

Top guest favorite

The cottage features a unique wooden exterior adorned with cedar shingles and a metal roof. Outdoor seating is arranged on an inviting deck area next to a woodpile. Large windows provide views of the surrounding landscape, creating a sense of connection with nature.

Home in Paonia

4.92 out of 5 average rating, 696 reviews

Private Cottage - King, Kitchen, Birders' Paradise

Kale's Cottage features a king size bed and is the epitome of unique and comfortable stays in Western Colorado. Our award-winning, pet-friendly Solargon boasts an elegant design, and is located just a half-mile walk away from the charming downtown of Paonia. The 374 sq ft space offers a fully stocked kitchen, seasonal wood stove, work/dining table & spacious private bathroom with shower. Whether for a special getaway, work, hiking, business or adventure, this is your perfect home away from home.

Superhost

An exterior view of the home reveals a blue siding with a set of wooden steps leading to a white door. A small patio area is visible with gravel underfoot, and a gas grill is positioned nearby.

Home in Cedaredge

4.78 out of 5 average rating, 50 reviews

Cedaredge Hideaway w/ Grill & Mountain Views!

Escape to Colorado’s high country and book a stay at this 3-bedroom, 2-bathroom vacation rental! Ideally located near endless outdoor adventure, this Cedaredge home allows for effortless time spent hiking, biking, fishing, and more. Spend your days shredding the slopes at the Powderhorn Mountain Resort or plan a day trip to Palisade and book a wine tasting tour. When you’re ready to unwind, return to this well-appointed abode to enjoy a home-cooked meal, then host a movie night on the Smart TV!

Guest favorite

The exterior of The Sunflower Cottage is shown, featuring wooden siding and warm string lights. A large window reflects the vibrant colors of the sunset, while a stone pathway leads to the front door. Open land extends in the background, capturing the serene rural setting.

Tiny home in Orchard City

4.94 out of 5 average rating, 209 reviews

Sunflower Cottage Stellarscape @Triple View Tiny's

Welcome to The Sunflower Cottage, a serene retreat in Western Colorado. Perfect for road trips and weekends away, this cozy hideaway offers everything needed for a comfortable stay. Guests love: -Cozy, clean, and charming -Stunning views and breathtaking sunsets -Amazing stargazing -Well-equipped kitchen and bathroom -Firewood for the fire pit -Proximity to Black Canyon and Grand Mesa -Access to outdoor adventures -Fast WiFi for remote work -Pet-friendly (additional fee) -Attention to details

Top guest favorite

An expansive covered deck features a cozy seating arrangement with four cushioned chairs surrounding a central fire pit. The deck is bordered by wooden railings, with a gas grill visible in the background. Scenic mountain views and natural surroundings are highlighted.

Home in Grand Junction

4.99 out of 5 average rating, 107 reviews

Secluded 6 Bedroom, 5 Bath with Views, Pool Table

Space, Location and Serenity! Amazing home beautifully situated on an acre and a half and only 1.5 miles to Main Street Downtown or head in the other direction and you are only 4 miles to the East Entrance of the National Monument. This oasis of nature overlooks the Lunch Loops Trails, has views of the Grand Mesa and the Nat'l Monument and is even frequented by deer. We have 6 bedrooms 5 baths with a pool table and over 3,300 square feet of living space waiting for you and your companions.

Guest favorite

A gravel outdoor area is featured with a fire pit surrounded by several bright blue Adirondack chairs. A smooth, neutral-colored wall serves as a backdrop, reflecting a clear blue sky above.

Townhouse in Grand Junction

4.94 out of 5 average rating, 72 reviews

Modern 2 BR townhome in central location

You will love this fully remodeled townhome with minimalist design and big functionality! Enjoy the CO sunshine in a private, fully fenced patio equipped with BBQ grill and outdoor dining. Cook your own meals in a fully stocked kitchen with high-end finishes. Get a good nights sleep on upgraded memory foam mattresses and deluxe pillows. Central air conditioning keeps you cool in the summer. Pets allowed for a fee of $20/night, 2 pet max. No cats, please. Common area has a fire pit and games.

Guest favorite

A covered hot tub is highlighted beneath a wooden pergola, featuring clear, bubbling water. Lush green foliage surrounds the area, providing a sense of privacy, while a glimpse of the home is visible in the background.

Home in Cedaredge

4.94 out of 5 average rating, 31 reviews

The Hidden Gem House- 3 bedroom House with Hot Tub

You will be close to everything when you stay at this centrally-located hidden gem. All conveniences, restaurants and shopping are within walking distance. Grand Mesa with over 300 lakes, Powderhorn ski resort, Gold Medal waters of the Gunnison River, organic orchards and vineyards, and Black Canyon of the Gunnison National Park are all just a short drive away. The comfortable beds, reclining sofas, fully-equipped kitchen, spa-like master suite and hot tub will make you never want to leave.

Top guest favorite

An open-concept living area features a high vaulted ceiling with wooden beams. Large windows allow natural light to fill the space, which includes a comfortable sectional sofa and a round ottoman. A decorative area rug is positioned on the wooden floor near a dining area with high chairs.

Chalet in Mesa

5 out of 5 average rating, 32 reviews

Large Cozy Chalet Near Powderhorn Resort

Relax and reconnect with family and friends at this spacious mountain retreat just 4 minutes from Powderhorn Resort's main lodge. Nestled in the aspen groves of the Grand Mesa, you and your guests will feel at home as you gather in the large kitchen to recall the highlights from your day on the mountain. Whether you plan to ski, snowmobile, bike, hike, or just enjoy the expansive National Forest that abuts the backyard, Cabina Bosco is the perfect home base for all your Colorado adventures!

Guest favorite

A welcoming porch extends along the front of the house, framed by lush greenery and climbing vines. The wooden deck offers a spacious area, with rocking chairs visible in the background, inviting relaxation and enjoyment of the outdoor surroundings.

Cottage in Palisade

4.96 out of 5 average rating, 67 reviews

A Cozy Orchard Retreat

Come Relax with the whole family; enjoy a float down the river and explore many of outdoor adventures. Or come enjoy a getaway weekend with wineries and vineyards galore, not to mention good food! Some of the best wineries are right down the street, one of which is just a block away. Your a short drive to Grocery stores, bike shops, bakeries, distilleries, breweries, restaurants, parks & more! Your home away from home!

Guest favorite

The image showcases a spacious outdoor area surrounded by a fence, home to several goats and two Great Pyrenees dogs resting. A blue shed is visible in the background, set against a backdrop of rolling mountains and lush greenery.

Camper/RV in Paonia

4.95 out of 5 average rating, 20 reviews

Wild Peony Farm with Mountain Views 1950 Spartan

Immerse yourself in stunning mountain views and starry skies in this lovingly restored 1950 Spartan vintage camper. Nestled against the backdrop of the West Elk mountains and a charming goat farm, this unique accommodation offers the perfect setting for stargazing, close access to hiking trails, wine tasting, farm-to-table dinners, cherry-picking, and more! Reconnect with nature at this unforgettable private escape.

Top guest favorite

A fenced backyard features a white gate, providing access to a grassy common area. Behind the gate, a spacious lawn can be seen, bordered by several residential buildings. The scene is brightened by a clear sky with scattered clouds.

Home in Grand Junction

5 out of 5 average rating, 17 reviews

Brookwillow Retreat- Modern Relaxation

*** New listing*** Discover comfort and convenience in our charming 3-bedroom townhome, ideally located less than five minutes from the bustling heart of Grand Junction's premier shopping corridor. Nestled in a vibrant neighborhood, Brookwillow Retreat offers easy access to an array of movie theaters, sport complexes, diverse restaurants, and boutique shops, making it the perfect retreat for families and friends.

Guest favorite

A cozy yurt is situated on a wooden deck, surrounded by lush greenery. Two blue adirondack chairs are positioned near the entrance, inviting relaxation. A hot tub is located to the left, providing an option for outdoor soaking in a serene natural setting.

Yurt in Grand Junction

4.93 out of 5 average rating, 279 reviews

High Desert Yurt

Get away from it all in our cozy yurt nestled in nature. This retreat offers modern comforts, including a full kitchen, private bathroom, and a hot tub under the stars. With heating and cooling, you'll be comfortable year-round. Enjoy the peaceful surroundings, just a short drive from town. Whether you seek relaxation or adventure, our yurt is the perfect base for your stay.