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Apartment vacation rentals in Lesbos Prefecture

Find and book unique apartments on Airbnb

Top-rated apartment rentals in Lesbos Prefecture

Guests agree: these apartments are highly rated for location, cleanliness, and more.

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Guest favorite
A modern living area features a grey sofa paired with a rustic coffee table on wheels. A large mirror reflects the space, while decorative lanterns and candles are arranged atop the table. The patterned rug adds a contrasting visual element to the floor.
Apartment in Mitilini
4.95 out of 5 average rating, 110 reviews

moonstone house B

Το διαμέρισμα βρίσκεται στον Α όροφο ενός παραδοσιακού κτιρίου! Ανακαινισμένο το 2018 με φροντίδα και προσαρμοσμένο στις σύγχρονες ανάγκες. Είναι ένας μοντέρνος χώρος με κλιματισμο που το κανει καταλληλο για καθε εποχη! Διαθέτει 2 υπνοδωμάτια με διπλα κρεβατια, μεγάλο WC με ντουζιερα, κουζίνα πλήρως εξοπλισμένη που συνδέεται με άνετο καθιστικό! Το σπιτι βρισκεται στο κεντρο της πολης! Τριγυρω θα βρειτε εστιατορια,μπαρ, καταστηματα,μνημεια,συγκοινωνιες !Παντου θα πατε σε 5λεπτα με τα ποδια!

Guest favorite
Two vibrant artworks are displayed on the wall, featuring deer adorned with floral designs and intricate patterns. The left piece depicts a deer with antlers embellished with colorful leaves and the right features a deer with a floral-patterned neck, both set against soft, muted backgrounds.
Apartment in Mitilini
4.96 out of 5 average rating, 207 reviews

Havenly Loft

Welcome to the "Havenly Loft"! Located in the very heart of Mytilene, our small (~35 sq.m.) , yet cozy apartment meets your every need; either for an early morning stroll by the pier, or a late night expedition into the unique culinary/beverage arts, immersing yourself into the hustle and bustle of the commercial district, or just relaxing in the park, your "anchor point" will always be a breath away. An inch away from the bus-stop to the airport and a 10 min walk from the port.

Guest favorite
A cliff-side infinity pool extends towards the blue Aegean Sea, reflecting the clear sky above. Sun loungers are arranged along the edge, providing a tranquil space for relaxation. Lush plants in white pots add a touch of greenery to the serene environment.
Apartment in Podaras
5 out of 5 average rating, 6 reviews

Filoxenia Retreat home with panoramic views

Flioxenia home is set in a beautiful small retreat complex called Aegean Blue. It is one of six self-contained guest apartments offering light, bright and stylish accommodation and all the amenities you could possibly need for an extended stay. All guests have full access to the Aegean Blue cliff-side pool, huge yoga/activity deck, communal facilities and gardens, with plenty of space from which to enjoy the spectacular views of the Aegean Sea and surrounding mountains.

Guest favorite
A small table is set with a pink placemat, featuring several books and brochures. Titles include a culinary guide and a travel book about Lesvos, showcasing colorful images of local cuisine and landscapes. A white router is positioned in the background near a window.
Apartment in Mitilini
4.84 out of 5 average rating, 108 reviews

cute independent apartment in the center

My home is in the city center. It is an independent little décor with all amenities and fast wi-fi, making guest accommodation comfortable and functional. Its picturesque and quiet neighborhood makes it special, although it is only a 2-minute walk from the beach, the market, the supermarkets, the restaurants and the nightlife of the city. The bus stop and the taxi rank are 2 minutes and 5 minutes to the port on foot.

Guest favorite
A spacious terrace is visible, featuring a dining table surrounded by six black chairs. A view of the sea and the surrounding buildings is offered, with warm evening light illuminating the area. Two glass doors lead into the interior spaces, enhancing connectivity.
Apartment in Mitilini
4.88 out of 5 average rating, 68 reviews

Castle View House

Stay in the heart of old Mytilene, in an authentic neighborhood with everything you need right at your doorstep. Wake up on the balcony with castle and sea views, stroll to the market, explore local tavernas, visit the castle, museum, and beach. Our home is comfortable and ideal for guests who want to truly experience the island, relax, and feel at home. We look forward to welcoming you!

Top guest favorite
An airy living area is presented with a comfortable gray couch, a round wooden dining table, and four chairs. The kitchen features light cabinetry and modern appliances, while natural light fills the space through multiple windows. Two woven poufs are placed on the floor.
Apartment in Skala Eresou
4.97 out of 5 average rating, 31 reviews

Depy's apartment 2

Located in the central square of Skala Eresos and 50m from the beach, our studio apartment is ready to welcome you. Fully equipped with electric appliances, wifi, ac, hot water 24/7 and fans above the beds. With anatomical mattresses and pillows and a couch that can become a bed. There is a balcony perfect for your morning coffee. Host name: Popy

Top guest favorite
A modern floor lamp stands next to a comfortable chair in a warmly lit corner. Soft light from the lamp creates a cozy atmosphere that highlights the rich textures of the chair and the nearby decorative plant.
Apartment in Mitilini
4.94 out of 5 average rating, 122 reviews

B DOIRANIS modern luxury apartment

Situated in the heart of the Old City of Mytilene, very close to town, restaurants, coffee shops and the harbor front, this brand new ground floor apartment offers an open living and kitchen area, 2 bedrooms and 1 bathroom. Air conditioning, furnished and equipped with dish washer and washing machine as well as wifi. Sleeps 4.

Guest favorite
A spacious bed is present, adorned with smooth, neutral bedding and pillows. A stylish floor lamp emits warm light beside the bed. Fabrics with subtle patterns cover the window, providing privacy while allowing soft light to filter through.
Apartment in Mitilini
4.8 out of 5 average rating, 386 reviews

Hidden gem now flat Checkpoint-Mytilene

Welcome to the queen of the Aegean sea, the island of Lesvos. Your accommodation is a 45 sq.m. first floor flat, few steps away from Mytilene's street market that can host up to 4 people. A hidden gem of the city, close to everything you may need. THE FLAT WILL BE SANITISED BEFORE EACH STAY.

Guest favorite
Apartment in Mitilini
4.86 out of 5 average rating, 146 reviews

#Tyrtaiou Modern Design Studio

Welcome to Tyrtaeus! It’s a professionally designed studio located in a traditional neighborhood, in one of the most central, yet quiet streets of Mytilene. Why does our proposal pose between the first options in the whole Northern Aegean? Certainly not by chance!

Guest favorite
An inviting sleeping area is equipped with a dark-patterned bedspread on a metal-framed bed. A wooden chair and a small table enhance the space, complemented by a cozy seating area. Wall-mounted artworks and a stone accent wall add character to the room.
Apartment in Mitilini
4.9 out of 5 average rating, 70 reviews

New Studio in the Center of Mytilene

Enjoy easy access to everything you need thanks to the ideal location of your base. It is close to the center of Mytilene, close to cafes, shops, restaurants, banks. 2 minutes to the waterfront and the city market and easy access to the castle and Tsamakia beach.

Top guest favorite
A potted flowering plant is situated on a wooden table, with vibrant orange blooms visible. In the background, the sea is seen gently lapping at the shore, while cars are parked along the coastal road under a clear blue sky.
Apartment in Petra
5 out of 5 average rating, 15 reviews

Colours of Summer - Mimosa

Πρόκειται για έναν καλαίσθητο χώρο ακριβώς μπροστά στη θάλασσα με εύκολο parking. Η πλατεία με τις καφετέριες και τα εστιατόρια καθώς και μαγαζιά, (markets, φαρμακείο, ιδιωτικό πλυντήριο ρούχων) είναι σε κοντινή απόσταση.

Guest favorite
A cozy sleeping area features a spacious bed covered with a vibrant yellow blanket and accented by a decorative pillow. A circular woven rug adds texture to the floor. Natural light filters through a partially covered window, with patterned curtains framing the view.
Apartment in Mitilini
4.71 out of 5 average rating, 78 reviews

COMFORTABLE GROUND FLOOR APARTMENT

A fully furnished and equipped apartment right in the center of Mytilene town. The house is located in the city market in a picturesque neighborhood. Everything is accessible without the use of a vehicle.

Popular amenities for Lesbos Prefecture apartment rentals

When is the best time to visit Lesbos Prefecture?

MonthFebMar
Avg. priceG$14,644 GYDG$14,853 GYD
Avg. temp9°C11°C

Quick stats about apartment rentals in Lesbos Prefecture

  • Total vacation rentals

    Explore 440 vacation rentals in Lesbos Prefecture

  • Nightly prices starting at

    Lesbos Prefecture vacation rentals start at G$4,184 GYD per night before taxes and fees

  • Verified guest reviews

    Over 6,500 verified reviews to help you choose

  • Family-friendly vacation rentals

    80 properties offer extra space & kid-friendly amenities

  • Pet-friendly vacation rentals

    Find 120 rentals that welcome pets

  • Vacation rentals with a pool

    30 properties feature pools

  • Rentals with dedicated workspaces

    110 properties have a dedicated workspace

  • Wi-Fi availability

    400 of Lesbos Prefecture vacation rentals include wi-fi access

  • Popular amenities for guests

    Guests love Kitchen, Wifi, and Pool across Lesbos Prefecture rentals

  • 4.8 Average rating

    Lesbos Prefecture stays are highly rated by guests—averaging 4.8 out of 5!