
Pet-friendly vacation rentals in Lake City
Find and book unique pet-friendly homes on Airbnb
Top-rated pet-friendly home rentals in Lake City
Guests agree: these pet-friendly homes are highly rated for location, cleanliness, and more.
Vacation rentals for every style
Get the amount of space that is right for you
Popular amenities for Lake City pet-friendly home rentals
Pet-friendly house rentals

Collins Quarters

Crystal Place Near MUSC and Mcleod Hospital

2b/1.5bath brand NEW townhouse Closed to MUSC

Spacious 3-Bed Home w/ Deck

Charming and spacious 4-bd 2 full ba WiFi, AC

Hideaway on Lake front for 7 guests

Spacious, Historic Home for 12 - Near Myrtle Beach

Lovely Cottage Close to Downtown w/EV chargers
Pet-friendly home rentals with a pool

Eagle & Birdie - 3 bedroom 3 bath on golf course!

Beach House with indoor pool!

Lakefront Farmhouse Retreat+Pool

Charming 2BR/2BA condo on True Blue golf course

Gray Man House Heated Plunge Pool

Wyboo Retreat at Lake Marion W/Pool

Surf and Turf Getaway!

19th Green @ True Blue Golf 2 bed 2 bath 1st floor
Private, pet-friendly home rentals

Tiny Home Dream!

The Hanna Farmhouse

South Carolina Lowcountry River Cabin

Lakefront Fishing + Grilling | Home Sweet Home!

A Lake Slice of Heaven

Cabin-cozy, Dog-friendly "Suite to Sea"

Big Mama's Lakeside Cottage Lake Marion

Three Little Birds Canal Cottage
Destinations to explore
- Western North Carolina Vacation rentals
- Atlanta Vacation rentals
- Myrtle Beach Vacation rentals
- Charleston Vacation rentals
- Gatlinburg Vacation rentals
- Outer Banks Vacation rentals
- Charlotte Vacation rentals
- Virginia Beach Vacation rentals
- Hilton Head Island Vacation rentals
- Savannah Vacation rentals
- Pigeon Forge Vacation rentals
- Jacksonville Vacation rentals
- Myrtle Beach Boardwalk
- Love's a Beach
- Huntington Beach State Park
- Garden City Beach
- Arrowhead Country Club
- Myrtle Beach National
- Caledonia Golf & Fish Club
- Myrtle Beach State Park
- Litchfield Beach and Golf Resort
- Tupelo Bay Golf Center
- Whispering Pines Golf Course
- Broken Groin
- Shipyard Village Building A - Litchfield By The Sea
- Pawley's Island parking lot South
- Litchfield Country Club
- Prestwick Country Club
- Debidue Beach
- Ceremony - Huntington Beach State Park
- Wild Water & Wheels
- Hyman Vineyards
- Palm Plantation