
Vacation rentals in La Mesilla
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Top-rated vacation rentals in La Mesilla
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Sky-filled “Studio Cielito” @ Rancho Los Sonadores
Welcome to Studio Cielito - a desert-inspired cottage designed with bath lovers in mind. Curated with vintage touches, luxury linens, and everything you need to relax and rejuvenate near the magical Sangre de Cristo Mountains. Just 8 mins from Meow Wolf and 14 mins from The Plaza, but surrounded by nature with a country feel. If your dates are not avail, click on our profile for our other rentals. **Due to COVID-19, we are asking that all guests be vaccinated to help keep our community safe.

Light Airy Spacious Retreat Between Santa Fe Taos
The Loft is a lovingly restored 300 year old adobe on the 2nd story of Rancho Manzana. Located on the historic Plaza del Cerro, in the world famous rural town of Chimayo. The main level features huge picture windows, soaring ceilings, a bedroom with a private claw foot soaking tub, a den with a double bed, & the sleeping loft with a double bed. There is a fully equipped kitchen, one bathroom with shower. Beautiful views and sunsets, overlooking the apple orchards and red cliffs in the distance.

Nambé Farm Stay
Join us on our organic veggie farm, 20 minutes north of Santa Fe and 25 minutes from Los Alamos, in beautiful Nambé. Our guest house is a stand alone casita with a fenced-in yard for your dogs, on our 5 acre working-farm property. The space has a large bedroom with king bed and writing desk, a living room with a comfy leather couch, tv with streaming capacity, a large bathroom with a tub, shower, washer/dryer, and a farmhouse kitchen to cook in. There is WiFi through-out. Pop-up cot available.

Santa Fe Super Dome
*READ ALL property info BEFORE BOOKING* Stay in the coolest spot in the Santa Fe area. New deck! Glamping dome on 8 private acres of ancient canyons, just south of Santa Fe on Hwy 14. Enjoy 360 degree views of every mountain chain in the area - Sangre de Christos, Jemez, Sandias, Ortiz, Manzanos. You even get Mt. Taylor, silhoutted in exquisite sunsets. This is the ultimate high desert glamping experience. Indoor plumbing, heat, stone shower, king bed. Personal Chef services available.

Viento del Rio - Abiquiu Casita W/Private Hot Tub
Viento del Rio is a perfect place to absorb the serenity of the Abiquiu area. Located off the beaten path (but not too far) centrally located to many area wonders. There are numerous places to hike nearby. Views of mountains (including Pedernal) in all directions are stunning. Nearby attractions include Plaza Blanca, Georgia O'Keefe Welcome Center and Ghost Ranch. Easy drive to Taos and Santa Fe. A truly lovely place to rest, relax and take in all the nearby sites and activities.

Hawk House
This cozy 2-story home sits on 10 acres in the Chama River Valley, with views of Cerro Pedernal and the mountains. Rustic, cozy, with all basic amenities. Ideal for the solo artist or couple. Hiking + hot springs nearby, including Ghost Ranch, Poshuouingue ruins & Ojo Caliente Springs! Most pets are welcome (for a pet fee). It's helpful to check in on it, however, due to our contained pups further back on the land. Open to longer stays at discounted price. Write about either to discuss!

Cozy Forest Escape with Private Hot Tub
Escape to a Peaceful Forest Retreat Nestled on a 1.5-acre wooded lot, this relaxing cabin offers the perfect retreat for nature lovers and adventure seekers. Located adjacent to the Valles Caldera National Preserve, our property boasts: - Relaxing Hot Tub: Unwind among the pines - Wildlife watching opportunities - Short drive to Fenton Lake for top-notch fishing - Modern comforts for a peaceful stay - Proximity to outdoor activities for all seasons: hiking, biking, fishing, and skiing

Charming Camper near Santa Fe
Newly renovated modern & spacious camper is located on a private gated 3.5 acre property in historic and beautiful Española River Valley, surrounded by 200 year old cottonwood trees and a running acequia. Located only 27 miles from Santa Fe, 24 miles from Abiquiu, 43 miles from Taos, 21 miles from Los Alamos, 12 miles from Chimayo, and 90 miles from Albuquerque, this relaxing & well-equipped camper provides the perfect getaway and home-base for your stay in Northern New Mexico.

Bonita Vista
Nambé, New Mexico in Santa Fe County quiet rural setting. It is located 20 minutes from Historic Santa Fe, surrounded by Ancient Anasazi hiking trails and ruins. On the High Road to Taos. Enjoy the peace of the country. Safe and friendly. Romantic, comfortable ,within a private compound. All the amenities of home. Star filled nights, quaint, beautiful accommodations and a charming shared garden to relax and enjoy the beauty of the view of the Sangre de Cristo Mountains.

Infinite Views | Ridgetop Retreat | 2 Hot Tubs
There's nothing quite like this in Santa Fe — a genuine Earthship eco-home on a secluded ridgetop, with two hot tubs and views that stretch to the Jemez Mountains. 🛁 2 hot tubs — indoor jetted spa with waterfall & rooftop infinity tub 🌄 Sweeping views of Santa Fe, the Jemez Mountains & National Forest 🌿 Rare Earthship design with living indoor gardens 🧘 Dedicated spa & yoga retreat 🏡 Spacious 2BR entire earth-home, secluded ridgetop setting

The Cabin - Tiny Home near Santa Fe & Los Alamos
Plan your vacation at this cute little cabin! The kitchen is furnished with a refrigerator/freezer, oven/stove, microwave, toaster, coffee pot and more. There is A/C and heating as well as a smart TV and Wifi so you can have a comfortable, relaxing, and productive stay! On top of all that, we are centrally located between Los Alamos, Santa Fe, Pojoaque and Taos so you can easily visit some of our most amazing tourist spots!

Luxury Desert Casita • Chiminea Nights • Views
Stay in a serene casita surrounded by the inspiring landscapes that shaped Georgia O’Keeffe’s art. Located just south of Ojo Caliente and a short drive from Ghost Ranch, this retreat offers effortless access to the area’s best hiking, hot springs, and high-desert beauty. With Ojo Mineral Springs only 14 miles away and dining within walking distance, it’s the perfect base for couples seeking both exploration and relaxation.
Popular amenities for La Mesilla vacation rentals
Other great vacation rentals in La Mesilla

High Moon 4 Ten Thousand Waves Way

Casa Chuparosa (The Hummingbird House)

Charming Chimayo Getaway

A Place of Refuge, Renewal & Escape

Cozy Santa Fe Casita with Views

Private Casita across from The Four Seasons.

Endless View Hot-Tub Chalet

Modern Dome Home near Santa Fe | Los Alamos | Taos
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- Santa Fe Plaza
- Ski Santa Fe
- Meow Wolf
- Sipapu Ski & Summer Resort
- Bandelier National Monument
- Georgia O'Keeffe Museum
- Santa Fe Farmers Market
- Museum of International Folk Art
- Rio Grande Gorge Bridge
- Santa Fe National Forest
- Loretto Chapel
- The Cathedral Basilica Of St. Francis Of Assisi
- El Santuario De Chimayo
- Taos Plaza
- Hyde Memorial State Park
- Pecos National Historical Park
- Valles Caldera National Preserve
- Vivác Winery
- Bandelier National Monument





