
Vacation rentals in La Mesilla
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Top-rated vacation rentals in La Mesilla
Guests agree: these stays are highly rated for location, cleanliness, and more.

Private Casita • Cozy Modern Retreat in Los Alamos
Over 100 five star reviews in 12 months reflect a consistently exceptional stay. Wake up to breathtaking Sangre de Cristo Mountain views in this cozy 350 sqft private casita—perfect for couples or solo travelers seeking comfort, calm, and a peaceful getaway. Enjoy a bright thoughtfully designed space with full privacy, private entrance, and fully equipped kitchen. Sip coffee with mountain views unwind, and relax in a calmed setting that guests love for its comfort, cleanliness, and atmosphere.

Happy Ram: Views! Beautiful. Peaceful. Upscale.
Want a unique, stylish, peaceful stay in Santa Fe? Happy Ram is an architect-designed, professionally decorated home on a 6.4-acre estate. Huge views of the Sangre de Cristo mountains from every room. Thick rammed earth walls create incredible quiet. Bedrooms on opposite sides of the home for maximum privacy. Patio with fireplace. Just 5 minutes to hip Tesuque Village, 6 to Four Seasons Resort, 11 to Santa Fe Opera, 14 to Santa Fe Plaza. Make your Santa Fe dream vacation come true! STRO-40172

Taos Skybox "Horizons" High Desert Retreat
Set on 30 acres of private land on the western edge of town, Taos Skybox "Horizons" studio is a unique vacation home experience, purpose-built to take advantage of the dark skies and endless vistas of the high desert landscape. Sitting at 7,000 ft. above sea level, views abound, as your retreat borders Taos Pueblo Native lands, yet is only 15 minutes from the Taos Plaza. Truly a memorable destination, Horizons is modern and well-equipped with a full kitchen, laundry, and fiber optic internet!

Hilltop Nest
Kick back and relax in this stylish cabin in the forest. Hilltop location with forever views. Just off scenic Route 66 (Hwy 50), up a steep (but short) driveway, sits a 2-bedroom log cabin with plenty of birdsong and pine trees, a porch surrounded by views and furnished with a grill for outdoor dining. Five miles east is the village of Pecos with the Pecos River for fishing, hiking, and exploring. Sixteen miles north is the legendary city of Santa Fe packed with world-class art and culture

Taos Earthship: Modern + Mesa
Located in the world-famous Greater World Earthship Community, this modern off-grid home is one of a kind! Built by hand over 8 years by me, your host, Kirsten. This sustainable house is bright, light, and airy with clean lines and unique details. Like all Earthships this house is built from natural and repurposed materials such as used automobile tires, cardboard, old cans and bottles. All electricity for the house is from solar. All water is from the sky. More comfort, less hippie.

Cozy Forest Escape with Private Hot Tub
Escape to a Peaceful Forest Retreat Nestled on a 1.5-acre wooded lot, this relaxing cabin offers the perfect retreat for nature lovers and adventure seekers. Located adjacent to the Valles Caldera National Preserve, our property boasts: - Relaxing Hot Tub: Unwind among the pines - Wildlife watching opportunities - Short drive to Fenton Lake for top-notch fishing - Modern comforts for a peaceful stay - Proximity to outdoor activities for all seasons: hiking, biking, fishing, and skiing

Top 1% | River Oasis | Hot Springs Nearby
Nestled at the base of a majestic mountain, Casa del Rio offers sweeping views of the mesa and river, with the Jemez River flowing right through the property. Modern amenities meet natural beauty—enjoy sunsets from the deck, s’mores by the riverside firepit, and drift off to the soothing sounds of the water. Just five minutes from hot springs and scenic hikes, and only an hour from Santa Fe or Albuquerque, it’s the perfect place to relax, explore, and make unforgettable memories.

Mary Ann's Mountain Retreat - Casita
Nestled up in the quiet Sangre de Cristo foothills in the sought after east side of Santa Fe, w breathtaking western views of the Jemez Mountains. 4 miles to the heart of town, 3 miles to Canyon Road, 1 mile to museum Hill. Just off of the historic Old Santa Fe Trail, up 3/10 of a mile up a private, maintained dirt road, in a rural gated community. Enter your cozy adobe, pristine casita. Ideal space for a romantic getaway, or solitary retreat. Across the porch from my Casa.

Charming Camper near Santa Fe
Newly renovated modern & spacious camper is located on a private gated 3.5 acre property in historic and beautiful Española River Valley, surrounded by 200 year old cottonwood trees and a running acequia. Located only 27 miles from Santa Fe, 24 miles from Abiquiu, 43 miles from Taos, 21 miles from Los Alamos, 12 miles from Chimayo, and 90 miles from Albuquerque, this relaxing & well-equipped camper provides the perfect getaway and home-base for your stay in Northern New Mexico.

Beautiful View
Nambé, New Mexico in Santa Fe County quiet rural setting. It is located 20 minutes from Historic Santa Fe, surrounded by Ancient Anasazi hiking trails and ruins. On the High Road to Taos. Enjoy the peace of the country. Safe and friendly. Romantic, comfortable ,within a private compound. All the amenities of home. Star filled nights, quaint, beautiful accommodations and a charming shared garden to relax and enjoy the beauty of the view of the Sangre de Cristo Mountains.

Hummingbirds Nest Earthship- Taos
Discover the magic of the Land of Enchantment in this unique, one-bedroom, one-bathroom custom Earthship. This sanctuary is thoughtfully crafted to blend seamlessly with its breathtaking surroundings, providing an immersive experience in luxury off grid living. Designed with sustainability at its core, the Earthship features solar power, rainwater collection, and propane systems, allowing you to minimize your environmental footprint while enjoying maximum comfort.

The Cabin - Tiny Home near Santa Fe & Los Alamos
Plan your vacation at this cute little cabin! The kitchen is furnished with a refrigerator/freezer, oven/stove, microwave, toaster, coffee pot and more. There is A/C and heating as well as a smart TV and Wifi so you can have a comfortable, relaxing, and productive stay! On top of all that, we are centrally located between Los Alamos, Santa Fe, Pojoaque and Taos so you can easily visit some of our most amazing tourist spots!
Popular amenities for La Mesilla vacation rentals
Other great vacation rentals in La Mesilla

High Moon 4 Ten Thousand Waves Way

Fish Abiquiu Lake, Hike Pedernal and Ghost Ranch

100 year old home in El Rancho, “Villa Vigil”

Luxury Tesuque Retreat, Hot Tub, Kiva Fireplaces

CasaAltaVista private with views

Abiquiu House Overlooking Plaza Blanca

The Green House

6-Acre Sanctuary|Dark Sky|Hot Tub|Dogs|Cowboy Pool
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- Ski Santa Fe
- Santa Fe Plaza
- Meow Wolf
- Sipapu Ski & Summer Resort
- Georgia O'Keeffe Museum
- Museum of International Folk Art
- Bandelier National Monument
- Santa Fe National Forest
- Santa Fe Farmers Market
- Rio Grande Gorge Bridge
- El Santuario De Chimayo
- Taos Plaza
- The Cathedral Basilica Of St. Francis Of Assisi
- Loretto Chapel
- Pecos National Historical Park





