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Vacation rentals in Jamestown

Find and book unique accommodations on Airbnb

Top-rated vacation rentals in Jamestown

Guests agree: these stays are highly rated for location, cleanliness, and more.

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Top guest favorite
A welcoming home exterior is displayed, featuring a tidy front yard with seasonal flowers and trees in the background. The spacious white house includes large windows and a covered porch, emphasizing its inviting characteristics.
Home in Georgetown
5 out of 5 average rating, 21 reviews

Luxury/Comfort home 3bedrooms/2 full baths

Unwind in this beautifully designed home, offering the perfect blend of comfort, and Southern charm. Whether you’re visiting for a relaxing getaway, a family vacation, or a business trip, this space has everything you need ✔ Stylish & spacious living areas ✔ Fully equipped kitchen✔ Comfortable bedrooms✔ Fast WiFi & Smart TV✔ Peaceful location, just minutes from historic Georgetown & local attractions.Nestled in the heart of Georgetown, close to scenic waterfront views, charming shops, and dining

Guest favorite
Home in Pawleys Island
5 out of 5 average rating, 7 reviews

Modern Costal Retreat - Close to Beach and Golf

5 minutes to beach. Beautifully renovated coastal home in Litchfield Country Club offering privacy, tranquility, and a prime location. Thoughtfully updated from top to bottom with high-end finishes, warm wood accents, and a bright open layout. Enjoy a peaceful, tree-lined setting with water and golf course views in the backyard. Just minutes to Pawleys Island’s beaches, world-class golf, and top dining. Kick back and enjoy the Lowcountry lifestyle with rare privacy just minutes from everything.

Top guest favorite
The exterior of a two-story house is nestled among tall trees, showcasing a deck with steps leading to the ground. Screened-in porches on both levels provide ample outdoor space and views of the surrounding greenery.
Home in Georgetown
4.98 out of 5 average rating, 184 reviews

Black River Refuge on the Water

The first guest comment I hear is "Wow - pictures don't do this place justice - the house is incredible and the views are spectacular! The next comment is "I thought we were way out in the country but it's only 20 minutes to the waterfront town of Georgetown, with shops, dining, museums and more. Looking to get away? This place is truly a retreat- a 3 bedroom house on the beautiful Black River in Georgetown. Four kayaks provided, swim or fish off the dock just a few steps from the house.

Guest favorite
A serene sunset casts warm hues over the water, with a houseboat moored alongside a covered dock. Silhouetted against the sky, fishing rods stand tall, and tall grasses frame the scene, enhancing the tranquility of this riverside setting.
Home in Georgetown
4.89 out of 5 average rating, 160 reviews

Maggie Jo’s paradise on the river !

Reconnect with nature at this unforgettable escape. Maggie jo is a 1970 completely restore houseboat. She has got a full size refrigerator , gas range ,microwave and toaster oven. Out on the back deck she has a gas grill. The aft berth has 2 full beds that are extremely comfortable. Galley dinette make into bed and the couch in the saloon pulls out also. While on the decks you will see eagles, dolphins , gator or fishing jumping out of the water. I also have 2 tandem kayaks for your use.

Superhost
An antique tugboat is anchored on calm waters, showcasing its sleek black hull and bright white cabin. Large windows provide an unobstructed view, while nearby flags flutter gently in the breeze. The surrounding area features a mix of greenery and docks.
Boat in Georgetown
4.74 out of 5 average rating, 34 reviews

Antique Tugboat on the Harborwalk

Welcome aboard this lovingly restored antique tugboat, moored just steps from the storied streets of Georgetown. Once a proud workhorse of American waterways, this vessel now offers a rare opportunity to experience life as it was in 1907—without sacrificing comfort. Let the scent of old pine and briny air greet you each morning as the harbor stirs to life. Cradle a warm mug of coffee as the sun lifts above the horizon, painting the masts and marshes in amber light. Your voyage awaits.

Top guest favorite
The living area showcases two gray sofas, a blue accent chair, and a dark wooden coffee table. Natural light filters through sheer curtains, with vibrant yellow decor accents on one sofa. A welcoming entry door with a circular window is positioned to the left.
Home in Andrews
4.89 out of 5 average rating, 46 reviews

Graceful Comfort

Discover the charm and comfort of our cozy country Airbnb, nestled in the heart of Andrews, SC. Perfect for a relaxing family getaway. Start your mornings with a cup of coffee on the screened-in porch, listening to the sounds of nature and soaking in the fresh country air. Inside, you'll find a warm and inviting atmosphere with comfortable furnishings, a fully equipped kitchen, and plenty of room for family and friends . Book your stay today and experience the charm of country living .

Top guest favorite
A brick front exterior is shown, featuring a covered porch with a bench and two rocking chairs. Potted plants are arranged neatly on either side, while a flower bed adds color at the base. The grassy lawn extends toward a driveway.
Home in Moncks Corner
4.92 out of 5 average rating, 109 reviews

Our Home is Your Home!

Home in a safe environment on a tidal creek joining the Cooper River. Extra parking on the two lots adjoining the home. 5 to 15 minutes away from Lake Moultrie, river access, and all local restaurants, grocery stores, and Walmart. Experience Berkeley County with a convenient app as a guide to discover local history and plan your outdoor activities. 20 minutes from Summerville and 45 minutes from historic downtown Charleston and the Dock Street Theater ( the first theater in the US).

Top guest favorite
A living area is arranged with floral-patterned seating and a wooden coffee table. Soft light from a nearby window illuminates the space, which features a circular braided rug and a lamp beside a comfortable armchair.
Home in Moncks Corner
4.98 out of 5 average rating, 85 reviews

The Brown Trailer

Welcome to The Brown Trailer in Pinopolis. It's a peaceful 3 bedroom, 2 bathroom older trailer that’s been well taken care of, sleeps up to 9 (7 in beds) with views of a pasture, use of a large backyard, and parking. Bring your boat as lake accesses to Moultrie start a 1/4 mile away with Cooper River accesses near by. Somerset, Wampee, Pineland Place, 108 W Main, Santee Canal as well as MC Regional Complex are minutes away, Summerville is 20’, and Downtown Chas is 45’. Come enjoy!

Top guest favorite
The exterior of the villa is shown, featuring a light-colored stucco façade contrasted by large windows. Surrounding landscaped areas include planters with vibrant greenery and flowers. A gravel pathway leads to the entrance, framed by the natural beauty of trees in the background.
Home in Summerville
4.92 out of 5 average rating, 170 reviews

Guest House/Villa

Enjoy your stay at this immaculately designed new build Villa. Located on a family property surrounded by 2 acres of trees, in a quiet rural neighborhood. Lots of privacy, peace and quiet, yet only 5 minutes from restaurants and stores. 15 minutes from Downtown Summerville, 40 minutes from Charleston and various coastal attractions. The villa is separate from main house and has no shared space other than the driveway. NO smoking, No pets. Laundry service available for long stays.

Top guest favorite
Farm stay in Hemingway
4.96 out of 5 average rating, 238 reviews

Quiet farmhouse near the beach

The best memories are made on the farm. Life is just better away from the hustle and bustle of city lights and busy schedules. Come stay in this recently renovated fourth generation 1950s farmhouse on an 80 acre working farm. Unwind on the porch, walk trails, find millions of years old sharks teeth, build a bonfire, pick blackberries, swim in the ponds, collect walnuts, or just relax while you’re here but don’t forget to wish on a dandelion or a shooting star before you leave.

Top guest favorite
A spacious bedroom features a black metal bed frame adorned with white bedding. Two stylish chairs are positioned beside large windows offering views of the surrounding landscape. A wooden dresser and a woven area rug add elements of comfort and warmth to the room.
Guesthouse in West Ashley
4.98 out of 5 average rating, 245 reviews

Large Guesthouse with Private Dock & Marsh Views

This newly built carriage house is separate from the main house. The cottage is about 1,200 sqft so it very open and spacious and great views of marsh and our tidal creek. We have a separate work area with desk and a massive dinning table if you need more room to work or to gather with friends. Full kitchen, washer and dryer, massive shower, the list goes on. You may not want to leave! Feel free to go sit and have coffee or cocktails on the dock. PERMIT# OP2025-06925

Top guest favorite
A field of blooming yellow flowers is displayed in the foreground, with delicate petals and green stems. In the background, a white farmhouse is visible, providing a serene country setting. The scene captures the tranquility of the flower field adjacent to the cottage.
Tiny home in Moncks Corner
4.95 out of 5 average rating, 162 reviews

The Goose Cottage at Wild Goose Flower Farm

Located next to the family farmhouse at Wild Goose Flower Farm, The Goose Cottage was designed to immerse guests in our calm and peaceful country life. We are located 15 minutes from the hearts of Cane Bay, Nexton and Exit 194 on I-26, and 45 minutes from Downtown Charleston. Two can sleep in the queen size bed but the sofa also extends into a queen-sized sleeper. Please reach out with further questions or if you would like to inquire about an extended stay.

Popular amenities for Jamestown vacation rentals