
Vacation rentals in Jamestown
Find and book unique accommodations on Airbnb
Top-rated vacation rentals in Jamestown
Guests agree: these stays are highly rated for location, cleanliness, and more.

★Delightful guest house near historic plantations★
Nestled in the Historic Plantation District between Summerville & Charleston, our timberframe "bunkhouse" offers privacy, comfort & convenience. This 850+ sq ft retreat includes full kitchen & bath, 2 dbl beds, twin bed & plenty of living space. There's a private entrance, so come & go as you please (we're right next door if you need us). Minutes from Middleton Place, Drayton Hall & Magnolia Gardens, an easy drive to dntn Charleston, historic S'ville, beaches & golf courses. *Now with WiFi*
4.98 out of 5 average rating, 777 reviews
Carolina Wren Cottage: New, Relaxing, Dog-Friendly
Charming dog friendly cottage located minutes away from historic Georgetown only about an hour from Charleston. Whether you want to sit on the large porch and enjoy listening to the birds sing or watch them fly back and forth through the beautiful trees. Maybe have an adventure walking along the Harbor walk do a little shopping and enjoy the great selection of restaurants. If that wasn't enough there are several beautiful beaches to enjoy. You won't be disappointed. For pets see policies.
4.96 out of 5 average rating, 197 reviews
Live Oak Lodge at Mauresina River Plantation
Take it easy at this unique waterfront home! Live Oak Lodge sits right on the Sampit river. It has its own boat ramp and fishing dock. There is a marina on the property where you can dock your boat. The marina is the only shared part of the property . It has oyster bar with fridge and sink. The house has massive decks and porches that give you unbeilable views of river and wildlife! The house has 3 bedrooms, 3 full baths,2 kitchens,2 screened porches, game room and incredible living room!
4.86 out of 5 average rating, 101 reviews
Your home away from home in Pinopolis
Nestled at the end of a quiet cul-de-sac, this house is close to Lake Moultrie & the Cooper River. It’s also very close to popular wedding venues: Somerset Point, Pineland Village, & Old Santee Canal Park. Moncks Corner Recreational Complex, where many tournaments are hosted, is also about 3 miles away. Pinopolis is less than 20 miles from Summerville & the Volvo area, 40 miles from coastal beaches, and just 45 minutes away from Downtown Charleston. It’s a great location for work or play!
4.98 out of 5 average rating, 180 reviews
Black River Refuge on the Water
The first guest comment I hear is "Wow - pictures don't do this place justice - the house is incredible and the views are spectacular! The next comment is "I thought we were way out in the country but it's only 20 minutes to the waterfront town of Georgetown, with shops, dining, museums and more. Looking to get away? This place is truly a retreat- a 3 bedroom house on the beautiful Black River in Georgetown. Four kayaks provided, swim or fish off the dock just a few steps from the house.
4.98 out of 5 average rating, 190 reviews
Luxury Farm Stay | Hot Tub, Pool & Animals
Welcome to The Days End Farm! Where modern comfort meets country charm 🌾 This home is for quiet stays only — no parties or events are allowed. A thoughtfully designed 700 sq ft farm cabin retreat tucked away on 11 acres of peaceful pastures. Located less than 45 min from downtown Summerville, 40 min from I-20, 1 hr from Downtown Charleston, and 25 min from I-95. We are a livestock property and for the safety of our animals we only allow 1 pet per reservation with a strict leash policy.
4.96 out of 5 average rating, 24 reviews
Graceful Comfort
Discover the charm and comfort of our cozy country Airbnb, nestled in the heart of Andrews, SC. Perfect for a relaxing family getaway. Start your mornings with a cup of coffee on the screened-in porch, listening to the sounds of nature and soaking in the fresh country air. Inside, you'll find a warm and inviting atmosphere with comfortable furnishings, a fully equipped kitchen, and plenty of room for family and friends . Book your stay today and experience the charm of country living .
4.91 out of 5 average rating, 57 reviews
Coast to Country
Welcome to Coast to Country, where farm boots and flip-flops both fit right in. Enjoy peaceful country living with easy access to coastal adventures. Wake to birdsong, explore trails or nearby beach towns, then relax under star-filled skies. Bring your horses, dog, or favorite people and enjoy a slower pace without missing the fun. Georgetown is 20 minutes away, Pawley’s Island 40. Cozy comforts, fresh air, and coastal charm make this the perfect escape from everyday chaos.
5.0 out of 5 average rating, 4 reviews
River House Escape
River front living with private dock. Bring the whole family to this great place with lots of room for fun. River House Escape offers an inclusive resort feel with your own private pool, half moon kiddie pool, and private dock with plenty of room to fish or tie up your boat if you plan to enjoy the Cooper River. The space is very close to popular wedding venues, trails at Old Santee Canal Park and just 45 minutes away from Downtown Charleston.
4.86 out of 5 average rating, 37 reviews
The Goose Cottage at Wild Goose Flower Farm
Located next to the family farmhouse at Wild Goose Flower Farm, The Goose Cottage was designed to immerse guests in our calm and peaceful country life. We are located 15 minutes from the hearts of Cane Bay, Nexton and Exit 194 on I-26, and 45 minutes from Downtown Charleston. Two can sleep in the queen size bed and one can sleep on the couch. Please reach out with further questions or if you would like to inquire about an extended stay.
4.95 out of 5 average rating, 174 reviews
Spacious 3-Bed Home w/ Deck
Escape to this spacious two story home. A 3-bedroom, 2-bath home with a relaxing deck and garage. Enjoy a bright, open living space perfect for families or groups. The fully equipped kitchen, cozy bedrooms, and modern amenities ensure a comfortable stay. Unwind on the deck, explore nearby attractions, or simply relax in this inviting retreat. Conveniently located for easy access to dining, shopping, and entertainment. Book your stay today!
4.82 out of 5 average rating, 44 reviews
The Wrenn’s Nest - Quaint National Forest Getaway
The Wrenn's Nest is a cozy two-bedroom cottage in the Francis Marion National Forest. Perfect for outdoor activities like hiking, fishing, and birdwatching, it offers a peaceful retreat with modern comforts. Located in Cordesville, SC, just 15 minutes from Moncks Corner, it’s surrounded by nature with few neighbors. Enjoy amenities like a laundry nook, fire pit, and a spacious lot. Guests are our priority, and we’re always here to help!
5.0 out of 5 average rating, 85 reviewsPopular amenities for Jamestown vacation rentals
Other great vacation rentals in Jamestown

The River House
5.0 out of 5 average rating, 40 reviews
Private Pondside Guest Suite
5.0 out of 5 average rating, 42 reviews
Lo & Billy’s Place a Historic 1940s Newlywed Cabin
4.99 out of 5 average rating, 84 reviews
Lakefront Cabin Compound w Private Dock!
4.96 out of 5 average rating, 25 reviews
The Condo
4.98 out of 5 average rating, 51 reviews
The Boat Shed
4.93 out of 5 average rating, 27 reviews
Moultrie's Lake Breeze - Your Home Away From Home
5.0 out of 5 average rating, 84 reviews
"The Nest" At Maple Hollow
4.96 out of 5 average rating, 23 reviewsDestinations to explore
- Atlanta Vacation rentals
- Sevierville Vacation rentals
- Myrtle Beach Vacation rentals
- Gatlinburg Vacation rentals
- Charlotte Vacation rentals
- Pigeon Forge Vacation rentals
- Savannah Vacation rentals
- Charleston Vacation rentals
- Jacksonville Vacation rentals
- Asheville Vacation rentals
- Hilton Head Island Vacation rentals
- North Myrtle Beach Vacation rentals
- Sullivan's Island Beach
- Garden City Beach
- Isle of Palms Beach
- Huntington Beach State Park
- Charleston City Market
- Bulls Island
- James Island County Park
- College of Charleston
- North Charleston Coliseum & Performing Arts Center
- Waterfront Park
- Rainbow Row
- Riverfront Park
- Shem Creek Park
- Caledonia Golf & Fish Club
- Magnolia Plantation & Gardens
- Hampton Park
- The Charleston Museum
- Lakewood Camping Resort
- Middleton Place
- White Point Garden
- Murrells Inlet Marsh Walk
- Angel Oak Tree
- Cypress Gardens
- Boone Hall Plantation





