
Vacation rentals in Jamestown
Find and book unique accommodations on Airbnb
Top-rated vacation rentals in Jamestown
Guests agree: these stays are highly rated for location, cleanliness, and more.

★Delightful guest house near historic plantations★
Nestled in the Historic Plantation District between Summerville & Charleston, our timberframe "bunkhouse" offers privacy, comfort & convenience. This 850+ sq ft retreat includes full kitchen & bath, 2 dbl beds, twin bed & plenty of living space. There's a private entrance, so come & go as you please (we're right next door if you need us). Minutes from Middleton Place, Drayton Hall & Magnolia Gardens, an easy drive to dntn Charleston, historic S'ville, beaches & golf courses. *Now with WiFi*
4.98 out of 5 average rating, 776 reviews
Carolina Wren Cottage: New, Relaxing, Dog-Friendly
Charming dog friendly cottage located minutes away from historic Georgetown only about an hour from Charleston. Whether you want to sit on the large porch and enjoy listening to the birds sing or watch them fly back and forth through the beautiful trees. Maybe have an adventure walking along the Harbor walk do a little shopping and enjoy the great selection of restaurants. If that wasn't enough there are several beautiful beaches to enjoy. You won't be disappointed. For pets see policies.
4.96 out of 5 average rating, 197 reviews
Live Oak Lodge at Mauresina River Plantation
Take it easy at this unique waterfront home! Live Oak Lodge sits right on the Sampit river. It has its own boat ramp and fishing dock. There is a marina on the property where you can dock your boat. The marina is the only shared part of the property . It has oyster bar with fridge and sink. The house has massive decks and porches that give you unbeilable views of river and wildlife! The house has 3 bedrooms, 3 full baths,2 kitchens,2 screened porches, game room and incredible living room!
4.86 out of 5 average rating, 101 reviews
Black River Refuge on the Water
The first guest comment I hear is "Wow - pictures don't do this place justice - the house is incredible and the views are spectacular! The next comment is "I thought we were way out in the country but it's only 20 minutes to the waterfront town of Georgetown, with shops, dining, museums and more. Looking to get away? This place is truly a retreat- a 3 bedroom house on the beautiful Black River in Georgetown. Four kayaks provided, swim or fish off the dock just a few steps from the house.
4.98 out of 5 average rating, 190 reviews
Your home away from home in Pinopolis
Nestled at the end of a quiet cul-de-sac, this house is close to Lake Moultrie & the Cooper River. It’s also very close to popular wedding venues: Somerset Point, Pineland Village, & Old Santee Canal Park. Moncks Corner Recreational Complex, where many tournaments are hosted, is also about 3 miles away. Pinopolis is less than 20 miles from Summerville & the Volvo area, 40 miles from coastal beaches, and just 45 minutes away from Downtown Charleston. It’s a great location for work or play!
4.98 out of 5 average rating, 180 reviews
Graceful Comfort
Discover the charm and comfort of our cozy country Airbnb, nestled in the heart of Andrews, SC. Perfect for a relaxing family getaway. Start your mornings with a cup of coffee on the screened-in porch, listening to the sounds of nature and soaking in the fresh country air. Inside, you'll find a warm and inviting atmosphere with comfortable furnishings, a fully equipped kitchen, and plenty of room for family and friends . Book your stay today and experience the charm of country living .
4.91 out of 5 average rating, 57 reviews
Our Home is Your Home!
Home in a safe environment on a tidal creek joining the Cooper River. Extra parking on the two lots adjoining the home. 5 to 15 minutes away from Lake Moultrie, river access, and all local restaurants, grocery stores, and Walmart. Experience Berkeley County with a convenient app as a guide to discover local history and plan your outdoor activities. 20 minutes from Summerville and 45 minutes from historic downtown Charleston and the Dock Street Theater ( the first theater in the US).
4.92 out of 5 average rating, 117 reviews
The River House
This magical riverfront home is waiting on you to come make lifelong memories. The sunsets have to be seen to be believed and you'll appreciate the comfortable elegance of both the layout and the décor. The private dock is the perfect place to stargaze or catch some rays during the day. Grill out on the porch or stay inside and use the kitchen, we've supplied anything you need for family meals at the custom built table. Come enjoy a jewel on the Waccamaw River in Pawleys Island, SC.
5.0 out of 5 average rating, 40 reviews
Coast to Country
Welcome to Coast to Country, where farm boots and flip-flops both fit right in. Enjoy peaceful country living with easy access to coastal adventures. Wake to birdsong, explore trails or nearby beach towns, then relax under star-filled skies. Bring your horses, dog, or favorite people and enjoy a slower pace without missing the fun. Georgetown is 20 minutes away, Pawley’s Island 40. Cozy comforts, fresh air, and coastal charm make this the perfect escape from everyday chaos.
5.0 out of 5 average rating, 4 reviews
Resort @ Kit Hall Pool & Gardens, near Charleston
Centrally located between Myrtle Beach, Mount Pleasant and Charleston SC ( closest beach 36 miles by car. A sanctuary with an amazing freshwater (not chlorine or salt but Ionized)swimming pool, between two national parks, The Francis Marion National Forest & Cape Romain Wildlife Refuge. Near waterways, hiking, cycling trails, fishing, low country dining, historical plantations and more. 2 bedrooms & a screened sleeping porch. 4 beds + library, kitchenette & 2 ba
4.96 out of 5 average rating, 161 reviews
River House Escape
River front living with private dock. Bring the whole family to this great place with lots of room for fun. River House Escape offers an inclusive resort feel with your own private pool, half moon kiddie pool, and private dock with plenty of room to fish or tie up your boat if you plan to enjoy the Cooper River. The space is very close to popular wedding venues, trails at Old Santee Canal Park and just 45 minutes away from Downtown Charleston.
4.86 out of 5 average rating, 37 reviews
The Wrenn’s Nest - Quaint National Forest Getaway
The Wrenn's Nest is a cozy two-bedroom cottage in the Francis Marion National Forest. Perfect for outdoor activities like hiking, fishing, and birdwatching, it offers a peaceful retreat with modern comforts. Located in Cordesville, SC, just 15 minutes from Moncks Corner, it’s surrounded by nature with few neighbors. Enjoy amenities like a laundry nook, fire pit, and a spacious lot. Guests are our priority, and we’re always here to help!
5.0 out of 5 average rating, 85 reviewsPopular amenities for Jamestown vacation rentals
Other great vacation rentals in Jamestown

Luxury Farm Stay | Hot Tub, Pool & Animals
4.96 out of 5 average rating, 24 reviews
Private Pondside Guest Suite
5.0 out of 5 average rating, 42 reviews
Lake Moultrie retreat
5.0 out of 5 average rating, 54 reviews
Cutest Cottage on the Lake
4.82 out of 5 average rating, 49 reviews
Lo & Billy’s Place a Historic 1940s Newlywed Cabin
4.99 out of 5 average rating, 82 reviews
Moultrie's Lake Breeze - Your Home Away From Home
5.0 out of 5 average rating, 84 reviews
Spacious 3-Bed Home w/ Deck
4.82 out of 5 average rating, 44 reviews
Quiet Retreat:Secluded & Idyllic
4.85 out of 5 average rating, 55 reviewsDestinations to explore
- Atlanta Vacation rentals
- Myrtle Beach Vacation rentals
- Charlotte Vacation rentals
- Gatlinburg Vacation rentals
- Savannah Vacation rentals
- Pigeon Forge Vacation rentals
- Jacksonville Vacation rentals
- Charleston Vacation rentals
- Hilton Head Island Vacation rentals
- North Myrtle Beach Vacation rentals
- Asheville Vacation rentals
- Raleigh Vacation rentals
- Sullivan's Island Beach
- Garden City Beach
- Isle of Palms Beach
- Huntington Beach State Park
- Charleston City Market
- Bulls Island
- James Island County Park
- College of Charleston
- North Charleston Coliseum & Performing Arts Center
- Waterfront Park
- Rainbow Row
- Riverfront Park
- Shem Creek Park
- Caledonia Golf & Fish Club
- Magnolia Plantation & Gardens
- Hampton Park
- The Charleston Museum
- Lakewood Camping Resort
- Middleton Place
- White Point Garden
- Angel Oak Tree
- Murrells Inlet Marsh Walk
- Cypress Gardens
- Boone Hall Plantation





