Vacation rentals in Isthmus of Panama

Spacious Casita with Bamboo View

Walk 20 minutes to the artisan mercado and restaurants on Ruta 71. Cerro Cara Iguana trailhead is walking distance from the casita. High insulated ceilings and 2 ceiling fans for comfort. Private hammock patio for an afternoon nap. Washer/dryer in the casita. Hot water throughout. Kitchen has a 2 burner cooktop, countertop oven, microwave, instant pot, electric skillet, blender and coffee maker. 2 Internet providers and a small workspace available. * No television set * Non smoking property

Beach House-Amazing Pool & Jacuzzi - Pet Friendly

Majestic Sands! Come relax with the whole family at this piece of paradise.located in a private beach community in Costa Esmeralda, San Carlos. Few minutes from the Pan-American highway and a few minutes from other local beaches such as Gorgona, and Coronado. It is a 5-minute walk to our beach, or if you prefer you can go by car. The home includes an amazing saltwater pool and hot tub with hammocks with views of amazing palm trees.Uninterruptible power with Smart Home Energy Management Systems.

Cozy open space, unique jungle views, river access

An open-style jungle home with mesmerizing treetop and mountain views. Located 10 minute walk to the beach, with a trail that leads to the River. The house is not childproof! It has three individual bedrooms, each with its own key. The price is based on the number of guests. The entire house is always yours. The house offers fiber optic WiFi and two dedicated workspaces. The property is surrounded by large trees, naturally keep the house cool and provide shelter for birds and wildlife.

FACING THE SEA Cacique (Portobello Park)

A house! A real glass island in the heart of the jungle! In the middle of the Portobello National Park (access only by 4x4 AWD) nestled at the top of the hill, between sky/sea, away from all eyes, a transparent house where glass embraces nature on all sides creating a unique connection between the inside and the outside, ideal for resting, disconnecting, comfortable, spacious, cool (central air conditioning), exclusive. It is the witness of a grandiose spectacle that awaits you!

Experience Rio Mar Penthouse

Experience unparalleled luxury in Rio Mar, San Carlos’ premier beachfront community near Coronado. This top-floor penthouse offers breathtaking ocean and mountain views from every room. Enjoy world-class amenities, including a surfing beach, sparkling pools, a spa, gym, and on-site restaurant. Relax in the elegant, open-concept living space with high-end finishes. Perfectly located near shops and attractions, this is the ultimate getaway for relaxation and adventure.

Ocean View Marina Stay in Buenaventura | By Alura

Enjoy an exceptional stay in this elegant and modern apartment, located on the top floor in the marina in Buenaventura, Panama’s most exclusive beach resort. It offers panoramic views of the Pacific Ocean and the Marina. The apartment is fully equipped with high-quality furniture and finishes, thoughtfully designed to provide both comfort and style. You’ll also have access to beach clubs, restaurants, and more, for a truly unforgettable resort experience.

Casco Viejo Dream Loft – Cozy & Central 1BR Apt

Enjoy a unique experience, in this elegant and centrally-located loft. Fully remodeled 1 bedroom apartment, in a central location in Casco Viejo (the old city). You will be just steps away from many restaurants, cafes, museums, and the existing night life casco has to offer. Located in “Casa Neuman",” this restored- colonial building and features unique crafted wall décor, as well as some of the original "calicanto" walls.

New ocean apartment in beautiful beach complex

Modern new condo with breath taking views of the Pacific Ocean. We are in a beautiful new beach complex, Punta Caelo, with direct beach access, a beach club, and several large swimming pools. The Social Area is resort quality with deck chairs, infinity pools, billiards, children’s pools and pool beds. The apartment is open and spacious with a fully stocked kitchen and large terrace directly looking out over the ocean.

Full apartment in Panama

This charming apartment is located in one of the best neighborhoods in Panama, San Francisco, a downtown location where you will find ample cuisine, entertainment venues, close to bus stations, and the city's most important shopping mall, Multiplaza. This central and quiet apartment is an opportunity you won't want to miss. It offers the perfect combination of comfort, beauty, and a convenient location.

Beautiful 1BR Condo Right on the Ocean

Sit back and relax in this newly furnished one-bedroom apartment, delivered in 2025, with a fully equipped kitchen and small family-friendly spaces, including a full bed perfect for children or an extra guest. It can accommodate up to 4 people. Located beachfront with direct access to the beach and several pools, this unit is perfect for a short or long stay and is situated on the 2nd floor.

Luxury Private Cottage in Altos del Maria

This property is situated within the gated community of Altos del Maria. Surrounded by lush forest and rivers, the loft @ Londolozi is for guests who appreciate a sense of luxury while being close to nature. While Altos del Maria enjoys a warm tropical climate, there is a cooling breeze in the mountains that is not often present in the coastal areas.

Luxury 2 Bedroom Condo, Playa Blanca Resort

Stunning Airbnb by Wynter Rosegold Designs, defined by her signature style of plush comfort, nature-inspired palettes, and ambient lighting. From beds you’ll never want to leave and thoughtful details for every need, her spaces are unique, functional, warm and luxurious. Wynter’s motto: "Creating a space you never want to leave."