Vacation rentals in Isla Palenque

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Top-rated vacation rentals in Isla Palenque

Guests agree: these stays are highly rated for location, cleanliness, and more.

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Top guest favorite

A spacious living area offers a direct view of the ocean, framed by large openings. A private pool sits in the foreground, with the horizon and distant islands visible beyond. Natural light fills the space, and outdoor lounging areas are positioned alongside.

Villa in Boca Chica

5 out of 5 average rating, 19 reviews

On the Beach Villa in Boca Chica!

Contemporary on the beach Villa with 180° Panoramic Ocean & island views of the Gulf of Chiriqui National Park. Open concept, indoor/outdoor living with private pool & spacious terraces for lounging, sunsets & stargazing. Perched on a cliff with direct beach access. Ocean breezes, tropical birds, exotic monkeys, iguanas & dolphins in the Bay. Private gated community. Large sand beach, perfect for swimming, boogie boarding, long walks, bocce ball or just relaxing & enjoying the sounds of nature.

Top guest favorite

A spacious living area features a comfortable sofa and two accent chairs surrounding a striped area rug. Floor-to-ceiling windows offer panoramic views of the ocean and surrounding islands, while a flat-screen TV is positioned on a low console for easy viewing.

Villa in Boca Chica

4.96 out of 5 average rating, 98 reviews

Sand Dollar Villa by the sea at Boca Chica Panama

Sand Dollar Villa by the sea This beautiful, very private retreat boasts panoramic views and direct access to a beautiful beach and sheltered bay. Located in Boca Chica, it is only 45 minutes from Panama’s second largest city, David. From your doorstep, you can enjoy island hopping in an archipelago of unexplored islands, or you can choose to soak in the sun on your very own private beach. Sand Dollar Villa offers the perfect décor for gracious living and entertaining in a magical setting!

Top guest favorite

Lush mountain landscapes are showcased under a clear blue sky, with gentle clouds drifting over the peaks. The greenery of the valley below blends with the rugged mountain terrain, providing a sense of tranquility and connection to nature.

Bungalow in Jaramillo

5 out of 5 average rating, 31 reviews

Panoramic Views Pacific to Baru, Boquete

Located in Alto Jaramillo our casita is nestled within a micro coffee plantation@ 4900ft elevation, and only 15 minutes drive from the center of Boquete! At this elevation you will have sweeping views from the Pacific to Volcan Baru and everything in between! Come and visit "SUKHA", and ancient term describing "Bliss" when you are looking to get away from it all, with easy access to all Boquete has to offer. *MAY-NOV IS THE RAINY SEASON, see notes under the property section on what to expect.

Top guest favorite

A welcoming living area features two colorful armchairs and a blue sofa, complemented by a glass coffee table. A modern kitchen with granite countertops is visible in the background, along with bar stools. An LED chandelier provides ambient lighting, and a wall-mounted television adds entertainment options.

Apartment in David

4.9 out of 5 average rating, 63 reviews

A 2 minutos del Centro Comercial

Te sentirás como en una suite de lujo en este espacioso, elegante y cómodo apartamento . Tu auto quedará en una zona segura y privada con cerca perimetral y cámaras de seguridad. A/C y Wifi en todo el apartamento, 2 TV smart. Tendrás una cocina completamente equipada. A menos de 2 minutos en auto podrás encontrar bares, restaurantes, almacenes, cafetería, bancos, supermercados, farmacias y más. Estarás a sólo 50 metros de la vía interamericana y a 2 minutos de la vía Boquete y Tierras Altas.

Top guest favorite

A private outdoor area features a pool surrounded by stone tiles and a covered seating area. Sun loungers are positioned under an umbrella, with views of green landscape and water in the background. The setting provides a serene atmosphere for relaxation.

Home in Playa Hermosa

5 out of 5 average rating, 40 reviews

Entire house with private pool facing beach !

Astonishing views, bird sounds & howler monkeys, Our region is designated by Panama as a Natural Water Preserve with 23 islands, lots of snorkeling, whale watching and beachcombing! One of the top best sport fishing destinations in the world! Casa Tanamera has a large garden set amidst the jungle. it boasts a plunging view on the beach and its entire bay area. the house is large enough for 4 persons, has large bedrooms and bathroom, a large patio with its dining, BBQ and lounge area.

Top guest favorite

A peaceful entrance is shown, framed by a landscaped garden. Soft lighting illuminates the pathway and steps leading to a welcoming door. Rolling hills can be seen in the background, complemented by a misty ambiance. The structure features large windows that enhance natural light.

Cabin in Alto Boquete

5 out of 5 average rating, 44 reviews

Ave Fénix, amplia, acogedora, ¡increíbles vistas!

Disfruta de la sencillez de este alojamiento tranquilo y céntrico. Diseñado para estar comodos, una cama queen "Murphy", la posibilidad de una mesa de patas extensibles donde trabajar. La misma se puede sacar afuera y disfrutar comer al aire libre. A unos 200mts de medios de transporte, o caminar 2km hasta el centro de la ciudad. A pasos de supermercado, estación de servicio, mercado gourmet, cafeteria, restaurantes y pasteleria. Tiene wifi de fibra optica, TV y lugar para el auto afuera.

Top guest favorite

A spacious room is visible through an open door, featuring a double bed with clean linens and a simple design. Natural light illuminates the area. A handcrafted wooden bench is placed in front of the bed. A potted palm adds a touch of greenery to the setting.

Guest suite in David

4.97 out of 5 average rating, 470 reviews

CasaMonèt

Suite con entrada independiente: estacionamiento techado, cama doble, baño sanitario, cocineta y escritorio. Tu espacio personal en el corazón de David. Cuenta con aire acondicionado tipo split, abanico de techo, TV con acceso a netflix, internet wifi gratis, cortinas black out, tanque de reserva de agua, agua caliente, cocineta equipada con estufa eléctrica, refrigerador, cafetera, microondas y utensilios básicos. No cuenta con lavandería, generador eléctrico y aislamiento acústico.

Guest favorite

A wooden cabin with a sloped roof is set amidst a lush green landscape. A well-maintained lawn features decorative plants and trees, while a pathway leads to the entrance. Large glass doors reveal a glimpse of the interior space.

Cabin in Alto Boquete

4.83 out of 5 average rating, 197 reviews

Las cabañas del francés - Nature & comfort

Descubra nuestro complejo de 6 cabañas de madera, equipadas con cocina, cama king y dos individuales en el altillo. Disfrute de una vista espectacular al barranco y un entorno natural impresionante. Estamos a 15 min de Boquete y 25 min de David en carro, lo que permite disfrutar de la tranquilidad sin alejarse de la ciudad. Áreas comunes con piscina y barbacoa para momentos inolvidables. Viva una experiencia única, combinando confort moderno y naturaleza en armonía.

Superhost

A spacious living area features large windows allowing natural light to flood the space. A blue sofa is complemented by decorative pillows. Textile art in various shades of blue adorns the walls. A wooden table with chairs is positioned for dining or relaxation, with greenery visible outside.

Villa in San Lorenzo District

4.82 out of 5 average rating, 17 reviews

Villa Turquesa with sea view in Isla Boca Brava

Welcome to Villa Turquesa, a true hidden gem on the stunning Boca Brava Island. This tropical retreat blends luxury, comfort, and adventure—all with spectacular ocean views. It accommodates up to 8 guests, features a fully equipped kitchen, shared pool, free WiFi, and easy access to Playa Las Cocas, just a 25-minute walk from the villa, as well as trails where you can spot birds and howler monkeys. Book Villa Turquesa now and let the sea breeze do the rest!

Guest favorite

A cozy seating area features a large, colorful sofa adorned with cushions in various shades of green and orange. Wooden chairs are arranged around a small table, and large windows allow natural light to fill the space while offering views of the surrounding greenery.

Home in Dolega District

5 out of 5 average rating, 14 reviews

Wanakaset River Front Charming 2BR, shared Pool

Casa Mariposa is a charming 2-bedroom villa located by the river in the heart of a lush 30-hectare forest at Wanakaset Panama. Ideal for up to 6 guests It offers direct access to the river for refreshing swims and peaceful relaxation. The house features a fully equipped kitchen, 2 modern bathrooms, and access to a large shared pool. Perfect for nature lovers seeking tranquility and comfort, Casa Mariposa is a serene escape surrounded by tropical beauty.

Superhost

Two contemporary cabins are shown, featuring angled roofs and striking orange accents. Floor-to-ceiling windows provide a view into the inviting lounge area. Surrounded by lush greenery and rock formations, the outdoor space offers a peaceful setting beneath a bright blue sky with fluffy clouds.

Cabin in Boquete

5 out of 5 average rating, 4 reviews

Cabaña en Alto Boquete 1

Welcome to Cabañas Piedra del Risco Our cabins were designed to offer the perfect balance between modern comfort and rustic charm. From the terrace, you’ll enjoy breathtaking views of the majestic Volcán Barú and the Caldera River canyon, surrounded by nature and the unique tranquility of Boquete. We’re located just 10 minutes from downtown Boquete—close enough to explore, yet far enough to truly disconnect. We’re Pet Friendly!

Guest favorite

The property features a spacious beachfront villa, framed by lush palm trees and open grass areas. A vibrant red roof contrasts with the white exterior, and the shimmering ocean is visible in the background, providing a serene coastal atmosphere.

Home in Playa Nanzal

4.9 out of 5 average rating, 10 reviews

Private Beachfront Getaway

Forget your worries in this spacious and serene space. Its seclusion is its charm. Escape from the busy city of David and kick back in our private beachfront property! There are little to no lights nearby, making for extraordinary sunsets/sunrises and star gazing. Whether you are a family looking to get away in the summer, a group of friends celebrating a birthday, or just looking for a break from life, this is the spot.