Family-friendly vacation rentals in Isla Grande

Find and book unique family-friendly homes on Airbnb

Top-rated family-friendly rentals in Isla Grande

Guests agree: these family-friendly homes are highly rated for location, cleanliness, and more.

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Guest favorite

A shaded terrace is decorated with a round dining table set for four, featuring white tabletop dishes and vibrant placemats. A hammock hangs nearby, surrounded by lush greenery and tropical plants, creating a serene outdoor setting.

Apartment in Centro

4.94 out of 5 average rating, 355 reviews

Walled City apt | Rooftop Pool + Private Garden

✨ Experience Cartagena’s Walled City with peace of mind. Spacious 1-bedroom retreat (1,066 sq ft) featuring a rooftop pool & private garden—steps from Plaza San Diego and La Serrezuela mall. Enjoy A/C, fast WiFi, hot water & elegant décor. Hosted by Airbnb’s Cartagena Community Leader & Superhost (300+ reviews, 4.95⭐). Trusted, loved & top-rated—book your Old Town escape today! ✨ Limited dates left—reserve now for exclusive rates & VIP local tips. Wake up to history, luxury & Caribbean charm.

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Guest favorite

Home in San Diego

4.91 out of 5 average rating, 411 reviews

Beautiful Private Home in Centro Historico, Pool.

This stylish unique house is located in the Centro Historico of Cartagena, in the trendy neighbourhood of San Diego. It is a tasteful home for a romantic hideout. This property offers a refreshing private pool, a small rooftop terrace perfect for sunset cocktails, A/C where needed and the option to cater for 5 guests. Right next to great bars and restaurants, this stylish Historical Colombian home is filled with great details, high ceilings, wooden beams, antique bath, and quality amenities.

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Guest favorite

A serene pool area is surrounded by tropical greenery, featuring a circular plant island at the center. Plush seating is available beside the pool, with draped curtains providing a sense of privacy. Soft lighting highlights the textured walls, creating a calming ambiance.

Home in Centro

4.91 out of 5 average rating, 235 reviews

Private Heated Pool+Jacuzzi | Colonial Walled City

Step into one of Cartagena's most iconic streets — Calle de las Damas — and into a beautifully appointed colonial home that blends centuries of history with every modern comfort. Located in the heart of the Walled City, Casa Calle de las Damas is the perfect base for experiencing the real magic of Cartagena. Whether you're traveling with family or a group of friends, this spacious 2-bedroom, 2 1/2-bathroom home offers an elegant and relaxed atmosphere you'll never want to leave.

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Top guest favorite

A rooftop terrace features a relaxing hot tub surrounded by lush greenery. Comfortable seating areas include wicker chairs and a wooden table, with stunning views of the city skyline and distant hills under a clear blue sky.

Home in Getsemany

4.99 out of 5 average rating, 130 reviews

Casa O Getsemani Lux Boutique House

Welcome to Casa O Getsemani! Immerse yourself in luxury at this new 4-story haven in in the coolest neighborhoods.Designed by the renowned architect Vladimir Caballero, our house accommodates 6 guests with utmost comfort. Enjoy complimentary delicious breakfast, airport transfer and attentive housekeepers. Elevate your stay with optional catering, entertainment, and exciting tours. Your unforgettable getaway awaits! Book now and create beautiful memories at Casa O Getsemani.

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Top guest favorite

A spacious loft suite is presented with an open layout, featuring a modern spiral staircase leading to a lofted sleeping area. Soft neutral tones and green plant decor enhance the environment. Seating arrangements include a large, curvy couch and a wooden table, creating a comfortable gathering space.

Apartment in Centro

4.99 out of 5 average rating, 109 reviews

Luxury Suite/Loft Apt/CityCenter

1 BR Loft Suite in the heart of Cartagena inspired by some of the finest 5 star Hotels in the world. Located inside the walls of the old city, within walking distance to shops, entertainment, restaurants, nightclubs & bars. Enjoy staying in this Unesco Heritage town full of history & excitement. Fully equipped kitchen with Washer/Dryer, Queen Sized Bed, TV, Netflix and 400MbWi-Fi. Our modern beach vibe apartment is perfect for a couple to enjoy and relax Insta @pombocartagena

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Guest favorite

A tranquil pool is framed by vibrant tropical plants and flowers, with petals scattered across the water's surface. A cozy outdoor space is visible in the background, featuring large pots and light curtains that invite natural light into the villa.

Villa in Getsemany

4.85 out of 5 average rating, 338 reviews

Luxury Villa in Cartagena

This luxurious four-bedroom Spanish-style villa offers 24-hour staff dedicated to ensuring a seamless stay, including daily cleaning and bed-making services. Indulge in gourmet meals prepared by the staff and enjoy exclusive access to a private boat for unforgettable day tours to nearby islands. Nestled in the charming colonial neighborhood of El Getsemaní, the villa is just steps away from the upcoming Four Seasons Cartagena, set to open in mid 2026. Come join us.

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Guest favorite

An aerial view showcases the tropical cabin nestled on a lush green hillside, surrounded by rocky coastline and the vibrant blue sea. The distant skyline of Cartagena adds contrast to the natural landscape.

Cabin in Cartagena

4.98 out of 5 average rating, 129 reviews

PAMADUIH - Cabin on the Ocean Cliff

Pamaduih is an exclusive tropical cabin located in one of the best places on the island of Tierra Bomba, ideal for lovers of the sea and nature looking to disconnect and relax. It is a cozy and heavenly space, with a unique panoramic view of the Caribbean Sea. About 20 minutes from Bocagrande, Cartagena, it offers exclusive access to the sea, a private dock, nearby unspoiled beaches, and surroundings rich in fauna and flora. Definitely an unforgettable experience.

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Guest favorite

A vibrant interior space features a colorful hammock, inviting relaxation. Bold artwork depicting aquatic plants and flowers covers one wall, while a well-equipped kitchen area is visible in the background. Soft lighting from decorative lamps creates a warm and welcoming ambiance.

Apartment in Getsemany

4.87 out of 5 average rating, 166 reviews

Loft in Getsemaní with terrace

RUSTIC AND ARTISTIC apartment on a third and fourth floor, in the traditional, picturesque and CHEERFUL Getsemaní neighborhood, Cartagena's Historic Center, near the bay, Plaza de la Trinidad, and the Clock Tower. On the third level is the bedroom, kitchen, bathroom and living area with private patio, and on the terrace a space with a 360-degree view. To access the apartment we must climb two stairs, one of them a spiral staircase. This is an old building.

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Guest favorite

An open space is showcased, blending a living area with a rustic wooden table and chairs. A blue couch offers seating, while an entertainment unit stands nearby. Natural light filters through large windows and a decorative arch, illuminating the exposed brick walls.

Home in Getsemany

4.89 out of 5 average rating, 209 reviews

Casa San Juan (Gethsemani)

The accommodation is located in the historic and beautiful neighborhood of Getsemani, which is full of colors and a lot of history that you should explore. It has magical streets with a lot of art, but the most valuable thing is its diverse people. The area is safe to walk. The accommodation is located in the historic and beautiful neighborhood of Getsemani, which is full of colors and a lot of history to explore. You can walk around the area safely.

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Guest favorite

A stylish living area features a cozy sofa with soft pillows, paired with two round tables. The warm tones of wood and subtle textures are complemented by an intricate patterned floor. Steps lead to an open kitchen area, visible in the background.

Home in Getsemany

4.88 out of 5 average rating, 214 reviews

Boutique house in the heart of Getsemaní Cartagena

Casa Sarda Getsemani offers an experience unlike any other. We are perfectly located for business travel or couple’s getaways, two minutes from the convention center and a few steps from the historic city center. The ancient walls and alleyways of the Getsemani historic area are full of local culture and bohemian spirit. This neighborhood is ideal to get the real spirit of Cartagena, away from the noisy and crowded streets of the historic center.

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Top guest favorite

An inviting courtyard showcases a small turquoise pool surrounded by lush greenery and potted plants. Rustic wooden beams support a terracotta ceiling, while arch-shaped windows frame the vibrant walls. A casual dining area with metal chairs is visible to one side, enhancing the serene atmosphere.

Home in Centro

4.9 out of 5 average rating, 146 reviews

Casa Rosada | Private Pool in Walled City

Casa Rosada is a beautiful 3-story colonial house in the San Diego neighborhood located within Cartagena's Historic Center. It has 3 bedrooms, sleeps 8. Enjoy this modern private house in the old city. The house is located in one of the most accessible and recognized areas of Cartagena's old town. This house is surrounded by some of the best restaurants, bars, squares, and shopping malls in this Caribbean city.

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Guest favorite

A serene outdoor area features a vibrant blue swimming pool surrounded by natural stone tiles. Lush greenery lines the space, while rustic brick walls and open columns create a seamless connection to the interior. Comfortable seating is visible in the background.

Home in Getsemany

4.91 out of 5 average rating, 161 reviews

Casa Linda

A charming two bedroom, 2 bathroom House in the heart of Getsemani, a few steps from Plaza de la Trinidad and Cartagena’s coveted restaurants, galleries and shops. The property includes a large living room, dining area, kitchen, outdoor patio and swimming pool. You will have a dedicated housekeeper every day (except Sundays & holidays).

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