
Vacation rentals in Isla Grande
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Top-rated vacation rentals in Isla Grande
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Islas del Rosario house with white sand beach.
Private beachfront house just 45 minutes from Cartagena, featuring the most beautiful white sandy beach in Islas del Rosario. • Beach bar & restaurant on site. • Kayak and paddleboard available. • Private dock with direct access to the house. • Perfect for snorkeling, swimming, and relaxing in turquoise waters. • Easy access to coral reefs. • Food and cocktail menu with restaurant service. • Daily housekeeping included. • Ideal for families, friends, or couples seeking comfort and exclusivity.

Enchanting Balcony Loft in Stunning 17th-C Mansion
It is a privilege to stay in a 17th-century mansion with a street-facing balcony in the heart of the Walled City of Cartagena de Indias. From your balcony, with your morning coffee or a glass of wine, enjoy a front-row seat to the vibrant Caribbean life of the iconic Calle Santo Domingo. Just steps from plazas, museums, cafés, and the city’s finest restaurants. The loft, exquisitely furnished, offers a refined experience of art and culture where history and comfort meet. Experience the magic ✨

Beautiful Private Home in Centro Historico, Pool.
This stylish unique house is located in the Centro Historico of Cartagena, in the trendy neighbourhood of San Diego. It is a tasteful home for a romantic hideout. This property offers a refreshing private pool, a small rooftop terrace perfect for sunset cocktails, A/C where needed and the option to cater for 5 guests. Right next to great bars and restaurants, this stylish Historical Colombian home is filled with great details, high ceilings, wooden beams, antique bath, and quality amenities.

Casa O Getsemani Luxury Boutique House
Welcome to Casa O Getsemani! Immerse yourself in luxury at this new 4-story haven in in the coolest neighborhoods.Designed by the renowned architect Vladimir Caballero, our house accommodates 6 guests with utmost comfort. Enjoy complimentary one airport transport, delicious breakfast, and attentive housekeepers. Elevate your stay with optional catering, entertainment, and exciting tours. Your unforgettable getaway awaits! Book now and create beautiful memories at Casa O Getsemani.

Beach House. A/C, Pools, Nature, Minigolf, Hot Tub
Beach House with 3 bedrooms and office, pools surrounded by nature, a rooftop with jacuzzi and minigolf. Perfect to watch the sunset with your loved ones! The home office has highspeed internet, ideal to work remotely while your family enjoys paradise. 2 minute walk from the home is our private community beach club with infinity pool, kid's pool, dock and beach access which you can enjoy at any time. The beach club area is shared with 10 other houses in our community.

Luxury Villa in Cartagena
This luxurious four-bedroom Spanish-style villa offers 24-hour staff dedicated to ensuring a seamless stay, including daily cleaning and bed-making services. Indulge in gourmet meals prepared by the staff and enjoy exclusive access to a private boat for unforgettable day tours to nearby islands. Nestled in the charming colonial neighborhood of El Getsemaní, the villa is just steps away from the upcoming Four Seasons Cartagena, set to open in mid 2026. Come join us.

PAMADUIH - Cabin on the Ocean Cliff
Pamaduih es una exclusiva cabaña tropical ubicada en uno de los mejores lugares de la isla de Tierra Bomba, ideal para los amantes del mar y la naturaleza que buscan desconectarse y relajarse. Es un espacio acogedor y paradisíaco, con una vista panorámica única del Mar Caribe. A unos 20 minutos de Bocagrande, Cartagena, cuenta con acceso exclusivo al mar, muelle privado, playas vírgenes cercanas y entornos llenos de fauna y flora. Sin duda, una experiencia inolvidable.

Casa Estribos | Stylish house inside Walled City!
CASA ESTRIBOS is privileged in its location, right in front of the Santo Domingo church, Cartagena’s first church built in 1573, and just 10 steps away from the Santo Domingo plaza as well as the “Fat Gertrudis” statue by the famous Colombian artist Fernando Botero. This unique space is fully equipped to meet your needs and is close to absolutely everything, making it a strategic spot to plan your visit around this magical city! NO UNREGISTERED VISITORS ALLOWED!

Casa Flamingo | Private Pool in Walled City
Casa Flamingo 🦩 es una hermosa casa colonial de 3 pisos en el Barrio de San Diego ubicada dentro del Centro Histórico de Cartagena. Tiene 4 dormitorios, capacidad para 8 personas. Disfrute de esta moderna casa privada en la ciudad vieja. La casa está ubicada en una de las zonas más accesibles y reconocidas de la ciudad vieja de Cartagena. Esta casa está rodeada de algunos de los mejores restaurantes, bares, plazas y centros comerciales de esta ciudad caribeña.

NOK Iconic 6BR Luxury Villa with Pool at Getsemani
Luxury colonial villa in Getsemaní with 24/7 staff for daily room cleaning and security. This iconic 6BR home features a private pool, rooftop terrace and daily breakfast. Located steps from Café Havana, it blends 200‑year‑old architecture with modern design for an unforgettable Cartagena stay. Recognized by Airbnb for having one of the best swimming pools in the world and featured in international architecture and lifestyle publications.

Tijereta Charming Island Cabin-Isla Grande EH
Our private cabin is a five-minute walk from the Caribbean ocean, on the Rosario Islands, one hour outside of Cartagena. It’s part of family-owned and operated Eco-Hotel Playa Libre, located on Isla Grande. A visit to our marine park island is a great option if you want to get off the beaten path, be immersed in Afro-Caribbean culture, and experience an eco-adventure.

Ojalá - Casa de Mar
🌊⛵🌴🪸✨ "OJALÁ" is an exclusive oceanfront place in the magical cove of Cholón, surrounded by beaches, corals and mangroves. It offers total exclusivity with a private dock, large spaces and exceptional service from our staff. Enjoy the tranquility, the Caribbean flavor and the sunsets that deserve a toast. 🌅🍹 Book and experience the magic of "OJALÁ"!
Popular amenities for Isla Grande vacation rentals
Other great vacation rentals in Isla Grande

Seafront/private/no vendors/near white s. beaches

Fantastic 3 Br House-Baru Grande

Luxury Oasis in Getsemaní | House with Jacuzzi

Casa Gaviota Baru Beach House a pasos del mar!

Cabin, Rosario Islands (Palma Plata)

Hotel Isla Pirata Junior Suite, 2 Bungalows.

King Ocean View Bungalow in Corona Island

Beautiful Premium Double Room with Ocean View
Destinations to explore
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- Cartagena Province
- Bocagrande
- Morros City Apartamentos
- Edificio morros Eco
- Santa Cruz del Islote
- Cholón (Islas del Rosario)
- Karibana Cartagena
- Playa Blanca
- Walls of Cartagena
- Plaza de Santo Domingo
- La Serrezuela
- Centro de Convenciones Cartagena de Indias
- Playa Blanca
- Plaza Bocagrande
- Historical Museum of Cartagena de Indias
- Las Bovedas
- Torre Del Reloj
- Morros Vitri Building
- Museo Naval del Caribe
- Convent of Nuestra Señora de la Candelaria de la Popa
- Catedral Santa Catalina De Alejandria
- Aviario Nacional De Colombia
- Mallplaza El Castillo
- Parque Plaza Fernández Madrid




