Vacation rentals in Edisto Island

4.92 out of 5 average rating, 201 reviews

Tranquility

Tranquility lives up to its name. Peace & quiet are the words guests use most to describe their visit. Less than 4 miles from the beach & 1 mile from the boat landing and hiking/bike trails, this is the place to unplug & reconnect with family & friends. To make sure you have a great vacation and know what to expect during your stay, it is important to read ALL information in our listing carefully. In addition to NOT being on the beach, several features make our home unique and not for everyone.

4.95 out of 5 average rating, 274 reviews

Guesthouse in Beaufort

Sunset River Cottage

Our quaint little River House rests on the beautifully natural marsh grass banks of the Whale Branch River in a quiet rural neighborhood. It is located only 9 miles from Historic Downtown Beaufort and 15 miles from Parris Island Marine Corps Recruit Depot. Hunting Island State Park's sandy beaches, nature tails, and lighthouse tours are a scenic 40 minute drive away. You can swim, fish, kayak or go boating right from the dock in our own back yard. When you arrive; you won't want to leave!

4.98 out of 5 average rating, 102 reviews

Marshfront Villa In The Trees - Near Beach & Bay

"The most unique and relaxing place to enjoy the tranquility and experience of Edisto. We did not want to leave" - Sambo Nestled atop 360-degree marsh views, you'll be immersed in the exotic natural beauty and wildlife of the Edisto sea island. Hear the waves crashing at the beach from the front porch and watch the marsh tides rise and fall from your choice of the many porches. "Nature with luxury.. our group loved floating from the house out to the inlet for private beach days" - JP

Treehouse in Saint Helena Island

4.98 out of 5 average rating, 117 reviews

"A" Secluded Quiet Oasis w/ Beach Pass

You'll love this unique and romantic escape. Architectual design allows you to fully take in the view of the lowcountry marsh. The backdrop of the bed allows you to fall asleep to the majestic starry filled night sky! Soak your cares away with a bath that will surely relax and unwind you. The background is breathtaking! The outside shower allows you to take in the scenery while enjoying a hot shower. This is an "unplug" listing, no tv or internet access. Hunting Island Beach Pass included.

4.94 out of 5 average rating, 112 reviews

Serene Edisto Beach Cottage Among Stately Oaks

Enjoy the island breezes on one of two screened in porches under beautiful oak trees. Located on the 5th fairway at Wyndham Resort. This three bedroom home with its open lofty living area and spacious master suite is the perfect family retreat. Wyndham offers amenities including three swimming pools, beach cabana with restrooms, tennis, gym and putt putt. Availability is not guaranteed. Please check with resort for pricing and availability. Home is wheel chair accessible including a ramp.

Cottage in Saint Helena Island

5 out of 5 average rating, 236 reviews

Harbor River Cottage

Romantic cottage on three-acres surrounded by gorgeous South Carolina waterways with endless views on all sides! Cottage is dog-friendly, has a fully-fenced front yard and screened-in porch. Full kitchen, private parking, washer & dryer, 55" TV with DirecTV. A short 10 minute drive from Hunting Island State Park, and 20 minutes to Downtown Beaufort and all the major attractions. Cottage is beautifully furnished with custom pieces to make this your ultimate low country luxury getaway!

4.9 out of 5 average rating, 58 reviews

Edisto Oceanfront Paradise w Panoramic Views

Fully renovated BEACHFRONT home - with sprawling views of the Atlantic Ocean! Featuring 4-bedrooms and 2-bathrooms! This is the perfect vacation spot on Edisto Beach! The kitchen features brand new appliances and has an expansive island topped with quartz countertops and is well stocked with dishes, pots/pans, utensils, etc. for cooking! This house is Coastal Paradise at it's finest - with charming modern decor and every need imaginable for a vacation home!

4.91 out of 5 average rating, 165 reviews

Condo in Edisto Island

422 Oristo Lodge

This Newly Renovated 1BR/ 1BA Efficiency Is Perfect For Escaping The Mainland Hustle And Bustle. Located Inside Ocean Ridge Resort On Edisto Beach, SC This Villa Has Many Features To Make Your Stay Relaxing And Comfortable. Queen Size Bed, Full Kitchen( Stove/Oven, Refrigerator, Microwave), Full Bath, Washer/Dryer, Cable Tv, Large Sundeck. Bed and Bath Linens Are Provided As Well As Departure Cleaning For Your convenience.

4.88 out of 5 average rating, 146 reviews

Condo in Edisto Island

★2BR Wyndham Condo on Golf Course 1/2m from Beach★

This 2/2 condo is located on the Golf Course in the Wyndham Ocean Ridge Resort, a quick walk to beautiful Edisto Beach. Spacious 1200 sq ft. Newer appliances incl dishwasher and w/d. Stocked kitchen. Extra large patio to enjoy the wildlife and watch the deer or oversee a game of golf. LINENS INCLUDED. Located on a quiet cul-de-sac yet close to conveniences. Note: 2nd floor location - stairs only. No Pets, please.

4.91 out of 5 average rating, 241 reviews

Newland’s Eyeland Steps away from the beach path

Dogs welcome with $100 non refundable pet fee. Our home is a traditional family beach house. A place to relax and refuel. We hope you will enjoy the laid back pace locals often refer to as Edislow. We provide a terrific location, clean home, linens, stocked kitchen, paper products (starter set) and several beach towels/chairs. Our hope is that you will kick up your feet and relax.

4.86 out of 5 average rating, 51 reviews

Little Boho Beach House ( Oceanfront Rental)

If you're looking for the perfect beachfront vacation rental, look no further than the Little Boho Beach House. Nestled right on the sandy shores, this charming getaway is the ideal destination for those craving a relaxing and rejuvenating beach escape. Accommodates up to 5 guests comfortably with 2 bedrooms. Perfect for couples, small families, or anyone looking for a cozy getaway.

4.9 out of 5 average rating, 563 reviews

Tiny home in Ravenel

CHARLESTON TINY HOUSE ON A GOAT MICRO-FARM

**FRESH UPDATES FOR 2025**Charming, award-winning Tiny House minutes from Historic Charleston and beaches! Collect the eggs, feed the goats, sit by the fire pit under the stars! Escape the hustle and bustle! Come relax with us close to the action yet worlds apart! **We prefer a 2 night weekend stay but if you see one night available, message me and we will get you booked!**

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Popular amenities for Edisto Island vacation rentals

Self check-in

Pet friendly

Laptop-friendly workspace

Gym

BBQ grill

Other great vacation rentals in Edisto Island

Cottage in Saint Helena Island

4.87 out of 5 average rating, 215 reviews

Cute Cottage Next to Hunting Island.

LisaRating, 5 stars1 week ago

Wonderful rental. Very clean and super quiet and private. A great place to recharge and enjoy nature. We enjoyed the short bike ride to Coffin Point Beach each day. Such a unique area with beautiful sunrises to view. For swimming, the pass to Hunting Island could not be beat. Location was close to shopping and a short drive to beautiful Beaufort to spend a day exploring the waterfront shops. The space was perfect for my teens and I. The house had everything I could ever need in the kitchen and in every space.

4.98 out of 5 average rating, 105 reviews

Lovely Edisto Beach home/a short walk to the beach

RickRating, 5 stars7 months ago

Absolutely beautiful home close to the beach. We loved the downstairs master, the patio, the spacious well appointed rooms, and the quick walk to the beach. Mary Jayne was responsive, kind, and everything you could ask of a host. Thank you for everything. Rick and Kat

5 out of 5 average rating, 22 reviews

Cozy Edisto Cottage - One block from the beach

KatieRating, 5 stars10 months ago

This house is super cute! We absolutely LOVED all the outdoor entertaining spaces, porches, decks and garage area. Walking distance from the beach and in a perfect location. This house was perfect for riding out tropical storm Debby. The house was one of the only houses on the island whose yard was not completely flooded. At one point during the storm we looked outside to see a ton of deer riding out the storm with us in the yard. We will definitely rent again.

4.92 out of 5 average rating, 24 reviews

The Marshpad, surrounded by nature, mins to beach

KathyRating, 5 stars2 months ago

The Marshpad is in a peaceful neighborhood surrounded by salt marsh, yet close to natural beaches, trails, a driving range and a golf course, and the grocery store and a crab shack for fresh fish. The house has lots of windows and decks to enjoy the views.

Cottage in Saint Helena Island

4.99 out of 5 average rating, 80 reviews

The Hideaway - Luxury Waterfront

KevinRating, 5 stars4 days ago

One of the most unique houses you will ever stay at. Really special.

Guesthouse in Saint Helena Island

4.99 out of 5 average rating, 220 reviews

Charming Waterfront Cottage with Beautiful Views.

HeatherRating, 5 stars1 week ago

Our 2nd stay at Marshsong was just as lovely as the first! Enjoyed morning coffee on the dock on the marsh and afternoon cocktails on the comfy bed swing on the awesome screened in porch by the pool. Mary Ellen has thought of everything and Marshsong is very comfortable, clean, beautifully decorated and well stocked. We enjoyed all the marsh birds, deer and other wildlife on her beautiful southern marsh property. Mary Ellen is a fabulous host & we will be back to her exquisite Marshsong!

5 out of 5 average rating, 131 reviews

Cottage in Beaufort

Private cottage in the pines

BethRating, 5 stars1 week ago

Christopher's beautiful little cabin was exactly what we needed while visiting Beaufort. We will definitely be back to stay everytime we visit!!