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Vacation rentals in Doña Ana County

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Top-rated vacation rentals in Doña Ana County

Guests agree: these stays are highly rated for location, cleanliness, and more.

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Top guest favorite
Guesthouse in Las Cruces
4.96 out of 5 average rating, 210 reviews

Quaint casita for 2

*Sep 2025 New bed/Aug 2024 New A/C mini split* Quiet cul-de-sac and peaceful landing spot within minutes to NMSU and Old Mesilla. Easy access to I-10 and I-25. Close to golf courses, shopping and the beauty of Las Cruces and Mesilla. Private entrance to casita, patio with dining table and a cozy bedroom, bathroom with tub/shower, WiFi, coffee station, refrigerator with small freezer, microwave. Wonderful hiking trails nearby and less than 60 minutes to White Sands National Park and ELP Airport.

Guest favorite
A room features a spacious bed dressed in white linens, complemented by a dark blue throw pillow. Natural light filters in through sheer curtains. A small table with a microwave and refrigerator is visible, along with a black rug on the floor and a fan in the corner.
Guest suite in Las Cruces
4.93 out of 5 average rating, 602 reviews

Tiny Cute Cubby in Telshor Hills, Private Entrance

The Cubby is perfect for overnight or short-term stays. Zero contact check-in and check-out. Access to central Las Cruces. Close to NMSU, Mesilla Valley Mall, major medical centers, and major event facilities. Located in Telshor Hills, a quiet neighborhood with plenty of mature trees and vegetation. Close proximity to observatory, minimal light pollution. Gorgeous views of Organ Mountains and Tortugas Mountain (A Mountain). Ten minute drive from historic Mesilla. Close to various hiking trails.

Top guest favorite
An aerial view of a Pueblo Style home is presented, showcasing a serene pool surrounded by a spacious outdoor area. The home is set against a backdrop of rolling hills and a cloudy sky. Desert vegetation is seen throughout the landscape, enhancing the natural beauty.
Home in Las Cruces
4.97 out of 5 average rating, 153 reviews

Desert Oasis with Pool

Pueblo Style home on 1+ Acre with Pool! This charming 4BR/2BA Pueblo Style home features stunning details throughout. Gorgeous saltillo tile in the living areas with beautiful wood beam accents, and a kiva-style fireplace for cozy winter nights. The primary suite offers direct access to the covered patio for summer dips in the pool and evening Sunsets. The 4th bedroom is huge and could be used as a second living area. The pool is not heated but will be open and cleaned all year. Sorry no pets.

Top guest favorite
A spacious living area is showcased, featuring a large sectional sofa with contrasting black pillows. Light wood beams accent the ceiling, while large windows provide a view of the outdoor space. A modern coffee table sits on a textured area rug, enhancing the inviting atmosphere.
Home in Las Cruces
4.99 out of 5 average rating, 196 reviews

Modern Luxury Home

This Luxury Modern Home is made to suit all guests! Whether you are looking for a weekend getaway or a place for work and play, this home has everything to offer in beautiful Las Cruces, NM. Located in a brand new neighborhood near Red Hawk Golf Course and multiple family-friendly parks. Guests can rest peacefully in one of 4 bedrooms and enjoy amenities such as an outdoor grill, outdoor living area, lawn games, board games, and most kitchen items. High-speed Internet included and SmartTVs.

Guest favorite
An interior space showcases wooden accents and a warm ambiance. A dining table with vintage-style chairs is set for guests, featuring tableware arranged neatly. Various mirrors reflect natural light from skylights above, while unique windows with shutters add character to the room.
Camper/RV in Las Cruces
4.96 out of 5 average rating, 104 reviews

The Stranded Time Traveler; a timeless experience!

Like something out of a fairy tale, the time machine's beauties are enchanting and memorable. Set somewhere in the past and present, it is being held in a large storage yard (plenty of space) because of flux capacitor issues while time marches on. Centrally located, it is about 3 mins. from NMSU, 5 mins. from Old Mesilla, the Billy the Kid court house, and the Farmers Market, 20 mins. from Dripping Springs Natural Area, 40 mins from El Paso, and 45 mins. from White Sands National Park.

Guest favorite
The image captures a clear salt-water pool with sparkling turquoise water under a bright blue sky. Sunlight reflects off the surface, while a yellow flowering tree and lounging chairs are visible in the background, creating a serene outdoor space.
Shipping container in Las Cruces
4.91 out of 5 average rating, 1,061 reviews

Nature Retreat 12-min from Downtown (with pool)

Re-purposed 40-foot shipping container w/Ikea cabinets & furniture at edge of desert. Loft is 1 of 2 dwellings on 5-acre lot, private exterior doors & adjacent reserved parking. Picture window with wonderful view of Organ Mountains. Compact kitchen, Serta PillowTop queen size bed, full bathroom, LED lighting, cooled/heated by modern heat pump, Wi-Fi Internet. Pool access in season (usually April-October). Hike/bike from doorstep. Pet-friendly, see House Rules for details/cost.

Top guest favorite
The entrance features a traditional adobe archway with purple wooden doors flanked by a rustic ladder. A lantern hangs above the opening, while desert vegetation is visible to one side. The backdrop includes distant mountains under a clear blue sky.
Guesthouse in Las Cruces
5 out of 5 average rating, 273 reviews

Desert Peaks Casita

This lovingly remodeled casita just fifteen minutes from downtown Las Cruces is open, spacious, and comfortably equipped for any length stay. Take in the views of the mountains, watch the birds, or relax in the hot tub under the stars. Hike to the Organ Mountains-Desert Peaks National Monument via an arroyo from the casita, take a dip in the pool, or rest in the peaceful and tastefully decorated space. It is a perfect place for a quiet getaway or as a base to explore the area.

Guest favorite
An open living area is showcased, featuring a large sectional sofa facing a mounted television. A wooden coffee table sits in front of the sofa. The kitchen is visible, equipped with modern appliances and bar seating, while large windows provide ample natural light.
Home in Las Cruces
4.89 out of 5 average rating, 241 reviews

Modern Accessorized 3-Bedroom

This fully-furnished modern home is perfect for weekend getaways or longterm stays. With latest in appliances and style, the Powder River Villa offers the comfort of home with a luxury feel. Stream Netflix in front of the stacked stone fireplace, decompress in the pebble rain shower, or simply relax on the back porch to the beautiful New Mexico sunsets. This stylish space can be the romantic escape you're seeking or comfortably fit your group of 7.

Top guest favorite
A modern interior features a wooden dining table with two black chairs, accompanied by a decorative bowl. A wall hanging adds texture, while a metal rack displays clothing and a woven basket. Natural light filters through a nearby window, highlighting the clean lines of the space.
Guesthouse in Las Cruces
4.99 out of 5 average rating, 197 reviews

Yucca Casita in Historic Mesilla

Mesilla STR Permit #0830 We have created a sustainable design, including rainwater harvesting and water saving landscaping, solar energy, energy saving and efficient construction, electric vehicle charger (which is solar powered), composting, organic gardens, firepit, and labyrinth.This is the 3rd unit (Yucca Casita) that we've completed, the 1st being our home and 2nd our other vacation rental property - Ocotillo Casita.

Top guest favorite
A charming casita features a turquoise door and a light exterior, framed by subtle landscaping. The sky is filled with vibrant orange and yellow hues as the sun sets, creating a striking contrast against the white walls and windows.
Guesthouse in Las Cruces
4.99 out of 5 average rating, 200 reviews

Cozy Casita De Mesilla

Cozy casita just steps from Old Mesilla’s historic plaza and coffee shops. Unwind in your private courtyard with a hot tub, or curl up by the fireplace inside the guesthouse. A kitchenette adds comfort for longer stays. Mesilla Bosque State Park by the Rio Grande is only 4 minutes by car—or a short bike ride—perfect for birdwatching, sunsets, and peaceful walks. The ideal spot for a romantic getaway or quiet retreat.

Guest favorite
A spacious outdoor area is captured, featuring a vibrant clay chiminea surrounded by gravel. Nearby, blue and terracotta pots add color. Lush greenery from trees and shrubs is visible, while a stone wall and gated entrance provide a sense of privacy and enclosure.
Home in Las Cruces
4.88 out of 5 average rating, 128 reviews

2 bed in Historic Mesilla, yard, pet friendly

Welcome to Casa de Sapo Verde! Nestled just outside the center of the historic Mesilla Plaza and on the edge of the area’s farmland, this cozy casita is the best of both worlds. Stay in this authentic Adobe home with vigas, coved ceilings, and brick floors and experience all Mesilla has to offer. Restaurants, galleries, and shops are all nearby, or you can stroll the ditch banks by neighboring farms.

Guest favorite
A warm sleeping area features a queen bed with a neutral quilt and accent pillows. Two bedside lamps illuminate the space with soft light. The ceiling showcases rustic wooden beams, while a framed artwork hangs above the bed, complemented by a textured area rug beneath.
Guesthouse in Las Cruces
4.94 out of 5 average rating, 104 reviews

Rustic Downtown Hideaway

This Rustic home has all the amenities, 1 Queen bed, couch sleeps small person or child, and walk-in shower. Inspired by the old west, this guest home has reclaimed wood and tin roof from an old barn in New Mexico. Within walking distance to cafes, restaurants, bars, and shops. Easy private access, keyless entry, and off street parking.

Popular amenities for Doña Ana County vacation rentals