Pet-friendly vacation rentals in DeSoto County

Find and book unique pet-friendly homes on Airbnb

Top-rated pet-friendly home rentals in DeSoto County

Guests agree: these pet-friendly homes are highly rated for location, cleanliness, and more.

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Guest favorite

Home in Hernando

4.91 out of 5 average rating, 211 reviews

Hernando Hideaway (Entire Lakehouse)

Enjoy our 2000 sq ft lake house in a private peaceful community with panoramic views of the lake. We are a licensed BNB with DeSoto County and the State of Mississippi until the year 2035. (Lic # 20110070) You will have the entire lake house to yourself and we provide coffee and pastries for breakfast. We are 15 minutes from Tunica Expo, 5 minutes to Tunica National Golf Course, 10 Minutes to the casinos; 38 minutes to Beale St, Bass Pro Shop, Peabody Hotel, Graceland and The Lorraine Hotel.

Jan 13 – 20

G$41,784 GYD per night

Guest favorite

Home in Southaven

4.9 out of 5 average rating, 58 reviews

Newly constructed, peaceful and cozy home

Newly constructed home built in 2019. The neighborhood is very quiet and safe. The home is 10 minutes from Memphis Airport; 2 minutes from I-55; less than 15 minutes from downtown Memphis, Orpheum Theater, FedEx Forum, Beale Street, Bass Pro Shop, and many other attractions; 2 minutes from North Creek Golf Course; 5 minutes away from restaurants, malls, grocery stores, Walmart, Target, movies theaters, etc. The perfect place to relax after a long eventful day! 6 exterior security cameras.

Jan 24 – 31

G$53,450 GYD per night

Guest favorite

Home in Southaven

4.82 out of 5 average rating, 148 reviews

Near Memphis, TN Mi Casa Es Su Casa

CLOSE TO MEMPHIS, TN 10 MINUTES AWAY VERY big house!! Walk-in closets. A 26X21 area with a pool table, playing card table, plenty of room for kids to play, entertain OR hang out. Front porch to enjoy the nights AND back porch to have your cookout. Driveway for several vehicles. Two homes on the property, rented separately. Like in the country BUT in the city. Tranquil, Safe, Close to shopping areas, gas stations, close to highways. Close to Snowden Grove. Very close to Memphis, TN

Feb 10 – 17

G$60,761 GYD per night

Superhost

Home in Hernando

4.77 out of 5 average rating, 61 reviews

Glamorous Vacation Home With Pool Table&Fireplace!

Bring your whole group to this newly remodeled and luxurious home! Great for families, friends, birthdays, and bachelor / bachelorette parties! We have a 3 bedroom 3 full bathroom house with a pool table, darts, cornhole, board games, fast Wi-Fi ,smart tv’s in every room ! Fully stocked Kitchen! Great location close by lots of restaurants and fun attractions! House sits on 5 acres of land with a pond in the backyard and yes you can fish if you like. Parking is free! Book Today!!!

Sep 3 – 10

G$28,947 GYD per night

Guest favorite

Guesthouse in Hernando

5.0 out of 5 average rating, 83 reviews

Cozy 2 Bedroom Guesthouse in a Relaxing Setting

Our two bedroom, two bath guesthouse is the perfect get-a-way from it all, yet close enough to everything you're looking to do: 3 minutes to the historic Hernando Town Square, 10 minutes to the MS River Delta and Historic Hwy 61, 12 minutes to Tanger Outlets & Landers Center in Southaven, 20 minutes to Snowden Grove Ballfields & Amphitheatre in Southaven, 23 minutes to Tunica Casino Strip, 25 minutes to Midtown/Downtown Memphis, 1 hour to Oxford, MS and 1 hour to Clarksdale, MS.

Jul 25 – Aug 1

G$29,161 GYD per night

Guest favorite

Home in Hernando

5.0 out of 5 average rating, 16 reviews

Studio Downtown! Clean, great location, sleeps 4!

Enjoy a stylish modern experience at Studio Downtown! Featuring 1 king bed and queen size sofa bed. Galley kitchen w/Keurig coffee machine, microwave, range and refrigerator. Full bathroom with walk in double shower. Laundry room with washer and dryer. Smart 65” tv and Wi-Fi. Very safe location in the historic district of downtown Hernando. Enjoy the multiple outdoor seating areas and corn hole boards. Within walking distance to restaurants and the town square. Owner/Agent.

Jan 2 – 9

G$30,966 GYD per night

Superhost

Cottage in Coldwater

4.95 out of 5 average rating, 162 reviews

Wynnewood - Odel Cottage

Country get-away! Only 30 Minutes from Downtown Memphis, TN, yet out in the country on a 62 acre estate. Nature trails through the property allow for beautiful, peaceful strolls. We have fishing (in season). **** This cottage is set back in the woods and there is not a TV in this unit. We have created a serene and unplugged experience. We have the "Wynnewood Elizabeth Cottage" and the "Wynnewood Jettie Jewel cottage" on our property that are listed separately.

Jan 28 – Feb 4

G$17,510 GYD per night

Guest favorite

Farm stay in Southaven

5.0 out of 5 average rating, 75 reviews

“The Longhorn House” at Blue Haze Farms

Get away from it all when you stay under the stars at our rustic tiny house. Kayak the lake or just take a hike. Sink into the memory foam mattress with luxurious linens and watch a movie on one of the smart TVs. Listen to some of our vintage records or play some old fashion board games ! Just want to relax? Curl up in the swing chair and watch our miniature Longhorns graze. Conveniently located south of Memphis, TN & Graceland. Relax. Unwind. Rejuvenate.

Sep 25 – Oct 2

G$41,430 GYD per night

Guest favorite

Guesthouse in Hughes

4.89 out of 5 average rating, 46 reviews

Horseshoe lake guest cabin

Near Memphis, TN This guest house is an open space L shaped concept. It will sleep 3 comfortably a king and full futon sofa in the living room. There is a full kitchen with all new appliances.This house is very comfortable with wifi and cable TV. There is a fenced yard for kids and animals to play. There is a charcoal grill. This house is across the street from the lake with ample parking and easy access to the lake for fishing and watching sunsets.

Dec 7 – 14

G$24,019 GYD per night

Guest favorite

Home in Horn Lake

4.97 out of 5 average rating, 60 reviews

The Vacation Home Thats Close To It All!

This home resides in a quiet cove in the Memphis Metro area of Horn Lake. Located: 15 minutes to Memphis International Airport 20 minutes from Midtown, Beale street, and the Fed Ex Forum. 5 minutes from the Landers Center. 5 minutes to Tanger Outlet Mall 4 minutes to I-55. 12 minutes Trips to Graceland ( The Home of Elvis Presley) 25 minutes to Horseshoe casino (Tunica) 25 minutes to Southland Casino (West Memphis)

Oct 17 – 24

G$59,382 GYD per night

Guest favorite

Cottage in Lake Cormorant

4.95 out of 5 average rating, 22 reviews

Green River Place House

Enjoy a historic getaway at this brand new farmhouse overlooking the beautiful Mississippi Delta. This is an experience you must see to believe. Artifacts from the Delta can be found throughout this beautiful establishment and the view from the front patio is breathtaking.

Apr 17 – 24

G$70,091 GYD per night

Guest favorite

Townhouse in Hernando

4.91 out of 5 average rating, 70 reviews

Charming Family Friendly Home

The house is nestled on a cove in a quiet family friendly neighborhood. You will experience a small town atmosphere and still be close to all the action. We are located approx 30 minutes from downtown Memphis or 30 minutes to the casinos in Tunica, MS.

Jul 22 – 29

G$31,919 GYD per night