House vacation rentals in DeSoto County

Find and book unique houses on Airbnb

Top-rated house rentals in DeSoto County

Guests agree: these houses are highly rated for location, cleanliness, and more.

%{current} / %{total}1 / 1
Superhost
The lake house is nestled among lush greenery, featuring large windows that provide views of the surroundings. Warm lights illuminate the exterior, creating a welcoming ambiance. A wooden deck leads to the entrance, surrounded by trees and natural landscaping.
Home in Hernando
4.87 out of 5 average rating, 246 reviews

Hernando Hideaway (Entire Lakehouse)

Enjoy our 2000 sq ft lake house in a private peaceful community with panoramic views of the lake. We are a licensed BNB with DeSoto County and the State of Mississippi until the year 2035. (Lic # 20110070) You will have the entire lake house to yourself and we provide coffee and pastries for breakfast. We are 15 minutes from Tunica Expo, 5 minutes to Tunica National Golf Course, 10 Minutes to the casinos; 38 minutes to Beale St, Bass Pro Shop, Peabody Hotel, Graceland and The Lorraine Hotel.

Top guest favorite
The en-suite bathroom features a spacious layout with an oversized vanity equipped with dual sinks and illuminated by elegant light fixtures. A glass-enclosed walk-in shower and a freestanding soaking tub are present, with a chandelier adding a touch of sophistication to the ambiance.
Home in Hernando
5 out of 5 average rating, 27 reviews

Peace of Heaven on a Hill

This Charming 2-Bedroom, 1 1/2 bath guest home is nestled on 4 acres right outside the city limits of Historic Hernando. Ideal for couples or small families, this home offers the perfect escape. Featuring an open concept kitchen/living space & a large master BR w/ an elegant bath suite. Enjoy time outdoors watching tv, relaxing on the porch swing, cooking on the grill, or gathering around the fire pit for s'mores. This home is located 10 miles from Snowden Grove & 1 Mile from Bolin Grove Farms

Top guest favorite
The kitchen features modern white cabinetry and a spacious countertop. Stainless steel appliances, including a refrigerator, microwave, and oven, provide functionality. A double sink is set into the countertop, while a window offers natural light with gray curtains adorning each side.
Home in Southaven
4.95 out of 5 average rating, 41 reviews

Close to Memphis NOT IN Memphis

Welcome to the Charleston Charmer. It is a peaceful centrally-located home. Nashville or Little Rock 3 hours. Interstate 55 2 miles. Graceland 15 minutes. Downtown Memphis 20 minutes (Grizzlies, Redbirds, Orpheum, FedEx Forum). Baptist Hospital 3 miles. Snowden Grove 7 miles. Enjoy all amenities of the city without the hustle and bustle. Minutes from restaurants, malls and shopping. Completely renovated inside. Private lock, dedicated workspace and large TV in all bedrooms. Come stay with us!

Top guest favorite
Home in Southaven
5 out of 5 average rating, 22 reviews

Stylish & Cozy~5 min to Landers CTR+ Fenced Yard!

Step into this stylish and comfortable living area. The home features two spacious bedrooms and a double futon for extra guests. Located just minutes from great dining and shopping. Fully fenced yard! ☆18 min to Memphis Airport ☆12 min to Snowden Grove ☆5 min to Landers ☆17 min to Graceland ☆Fenced yard ☆USB plug in ☆Free parking ☆Dedicated workspace ☆Washer/Dryer ☆Roku TV in both bedroom ☆BBQ ☆Patio with Pergola ☆Fully stocked kitchen ☆Self check-in/digital guide book ☆5 min walk to park

Guest favorite
A versatile living space features a large wall-mounted television opposite a desk with an adjustable lamp. A classic arcade machine adds a playful touch. Natural light enters through two windows, complemented by decorative mirrors and a potted plant in the corner.
Home in Southaven
5 out of 5 average rating, 34 reviews

Your Stay at The Top of Mississippi

*Stylish Renovated Townhome in Southaven, MS* - Features 2 bedrooms, each with its own vanity. Primary bedroom with king bed, the second bedroom features two full-size beds. - Free wifi, fully equipped kitchen, washer and dryer. - Situated just 12 minutes from Memphis Airport, 20 minutes from downtown Memphis, and only minutes from local restaurants and parks. Plus, it’s only 5 minutes from the local hospital, making it a great choice for medical professionals or visitors. -No smoking

Top guest favorite
The front of a two-story brick house features a gabled roof and a white garage door. A well-maintained driveway leads to the entrance, bordered by green grass and trees in the background. A clear blue sky provides a bright backdrop.
Home in Southaven
4.88 out of 5 average rating, 50 reviews

Family Getaway Home

Bring the family to enjoy. We offer lots of room for you to enjoy during your stay. 4 bedrooms with one of them having a full size air hockey table. Home offers a covered patio to sit and enjoy as well. Home is located in a nice quiet cove in the heart of DeSoto County. This home is convenient to lots of great restaurants and things to do. Downtown Memphis is a short 25 minute drive as well , home of the Memphis Tigers. Come , relax , and enjoy . Note - This is a nonsmoking home 😊

Top guest favorite
The studio features a spacious sleeping area with a king bed, complemented by a soft green sofa and a decorative area rug. A dining table with chairs is positioned nearby, and warm wood cabinetry can be seen in the background, opening to the galley kitchen.
Home in Hernando
5 out of 5 average rating, 44 reviews

Studio Downtown! Clean, great location, sleeps 4!

Enjoy a stylish modern experience at Studio Downtown! Featuring 1 king bed and queen size sofa bed. Galley kitchen w/Keurig coffee machine, microwave, range and refrigerator. Full bathroom with walk in double shower. Laundry room with washer and dryer. Smart 65” tv and Wi-Fi. Very safe location in the historic district of downtown Hernando. Enjoy the multiple outdoor seating areas and corn hole boards. Within walking distance to restaurants and the town square. Owner/Agent.

Guest favorite
Home in Hernando
4.88 out of 5 average rating, 8 reviews

Three Bedroom Home - King Bed - Full Kitchen

Beautiful Colonial home perfect for up to 6 guests. Complete with three bedrooms, three and a half baths, master bedroom has its own private bathroom, full kitchen, appliances, washer and dryer, wi-fi, TV, and security system -- all to yourself. Very quiet and peaceful – centered on the historic Hernando Square. Relax and spend your day with free access to the nearby Hernando Golf & Racquet Club as part of your stay with dinning, swimming pool, golf and tennis available.

Guest favorite
Home in Southaven
5 out of 5 average rating, 5 reviews

Memphis/Southaven Entire Home

Perfect for traveling nurses, Doctors, workers, insurance claims OR long stay or short stay peaceful and centrally-located place. Close to hospitals, University college, Delta College, Graceland, Beal Street, Snowden Grove Baseball Complex, Landers Stadium & Arena, Memphis Airport, Casino, Church, Walmart, Hospitals, Sam’s, Eating Places Spacious and very quiet one bedroom, full kitchen with washer and dryer, salon bath. Pet welcome.

Guest favorite
A well-appointed bathroom features a double vanity with stylish round mirrors above each sink. Soft lighting is provided by decorative sconces, enhancing the serene color palette of light blue cabinetry and neutral walls. A spacious shower area is separated by a white curtain, and plush bath mats are placed on the floor.
Home in Southaven
5 out of 5 average rating, 12 reviews

Casa de Magnolia Townhome near Tanger Outlet Mall

Casa de Magnolia is conveniently located in North Mississippi! A stones throw to Graceland, Home of Elvis, Tanger Outlet Mall, Casinos, and all things Memphis and Mid South. This beautifully decorated two-bedroom, 2 ½ bath home is perfect for families or friends looking to relax and unwind. Casa de Magnolia is perfect for families. She is first class all the way. Casa de Magnolia has everything you need for a restful stay.

Top guest favorite
Home in Olive Branch
5 out of 5 average rating, 14 reviews

Suburban Comfort - 7 minutes from Silo Square!

Kick back and relax in this calm, cozy space! This beautiful home is located in between Southaven, MS and Olive Branch, MS. Conveniently located near the Silo Square, South Point Grocery Store, Bank Plus Amphitheatre, Landers Center, Snowden Grove Park, Target, Tanger Outlets, local restaurants, grocery shopping, parks, hospital, schools, and many more! A perfect place to stay for vacation, work, visiting family, etc.

Guest favorite
A bright and airy living area features a yellow sofa adorned with dark, textured pillows. A wooden coffee table sits in front, accompanied by decorative candles. Light-colored curtains frame a window, while artwork depicting floral scenes is displayed on the wall, adding a touch of elegance.
Home in Southaven
4.9 out of 5 average rating, 84 reviews

Pocketful of Sunshine

Enjoy a stylish experience at this centrally-located house. Close to the Tanger Outlet Mall, Southaven Town Center, Tons of restaurants. Only 9 Miles from the Memphis International Airport, 11 Miles from Graceland, 17 Miles from Beale Street. Two Bedrooms, Two Baths with all the amenities of home. Come and enjoy your private home away from home.

Popular amenities for DeSoto County house rentals