
House vacation rentals in DeSoto County
Find and book unique houses on Airbnb
Top-rated house rentals in DeSoto County
Guests agree: these houses are highly rated for location, cleanliness, and more.
Vacation rentals for every style
Get the amount of space that is right for you
Popular amenities for DeSoto County house rentals
House rentals with a pool

The Memphian Manor - Your Private Estate

Luxe Midtown Pool Home-Beale St, Graceland-10 mins

Eclectic 4 Bedroom Getaway!

Entire Estate in the Heart of Memphis!

Family Friendly home near Graceland

Spacious Southaven Home on 8 Acres w/ Private Pool

Cori's Pool House

Mini-Golf ~ Heated Pool ~ Hot Tub ~ Game Room
Weekly house rentals

Escape to Green T Lake Retreat

Cozy Cottage in Horseshoe Lake

perfect place for travelers

Cozy Miss - Peaceful - Modern - Comfy Bungalow!

Peace of Heaven on a Hill

The 4BR Vacation home Close To All

Pickleball House at Bonne Terre

Casa de Magnolia Townhome near Tanger Outlet Mall
Private house rentals

Classy 4bdr Home Newly built

Cheerful 3Bed/3bath home with Fireplace & patio!

center of southaven home

Spacious home in Southaven.

The Hideaway at Horseshoe Lake

A Serene Stay in Southaven

Family & Pet Friendly - Backyard - Patio

The home away from home
Destinations to explore
- Kid-friendly rentals DeSoto County
- Rentals with pools DeSoto County
- Rentals with a fireplace DeSoto County
- Rentals with outdoor seating DeSoto County
- Rentals with a washer and dryer DeSoto County
- Pet-friendly rentals DeSoto County
- Rentals with a patio DeSoto County
- Fitness-friendly rentals DeSoto County
- Rentals with lake access DeSoto County
- Rentals with a fire pit DeSoto County
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- Memphis Zoo
- FedExForum
- Shelby Farms Park
- Overton Park
- Orpheum Theatre
- Memphis Botanic Garden
- Village Creek State Park
- Spring Creek Ranch
- The Ridges at Village Creek
- Memphis Country Club
- de terra Vineyard & Wines of Somerville
- Mississippi River State Park
- Chickasaw Country Club
- Stax Museum of American Soul Music
- National Civil Rights Muesum
- Old Millington Winery