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Family-friendly vacation rentals in DeSoto County

Find and book unique family-friendly homes on Airbnb

Top-rated family-friendly rentals in DeSoto County

Guests agree: these family-friendly homes are highly rated for location, cleanliness, and more.

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Home in Venice

4.78 out of 5 average rating, 113 reviews

South Venice, FL. Ideal vacation home.

Located in a desirable community of South Venice . Venice, Manasota and Sharky's beaches are located only 5 miles away. The Historic Venice avenue of unique shops, restaurants, special events, Farmer's Market, tennis courts and Children's Fountain are close by. Newly Renovated home in a quite and peaceful area is an ideal place for any season gateway. A great place for biking, running, walking. My place is good for couples, solo adventurers, families (with kids), and furry friends (pets).

Nov 8 – 15

G$22,310 GYD per night

Home in Port Charlotte

4.85 out of 5 average rating, 213 reviews

Peaceful Port Charlotte 2Bd/2Ba on water

Are you ready to unwind with your friends, partner or the entire family? Look no further than the Comfy Conway. It is close to restaurants, beaches, family-friendly activities and peaceful spots to re-energize. Whether here for business or pleasure, your stay will exceed expectations. I take great pride in making sure guests are comfortable and well taken care of. Stay and enjoy the house amenities or venture out to the great amenities offered by the beautiful surrounding Port Charlotte area.

Jun 1 – 8

G$30,692 GYD per night

Home in Venice

4.9 out of 5 average rating, 162 reviews

Venice Pool Villa with Bikes Kayaks Great Beaches!

Relaxing pool home with 2 bedrooms, 1 king bed, 1 queen bed, 1 sofa double bed and one single foldout bed. 2 bathroom pool home just a 8 minute ride away from Manasota beach. Venice beach and caspersons beaches close by too. A great selection of restaurants and plenty of shopping and convenient grocery stores just 5 minutes away!. Also close to bike trails with two FREE bikes at the house and FREE kayaks too. My home is great for everyone! Pets welcome with pet fee, large fenced yard!

Dec 7 – 14

G$31,991 GYD per night

Condo in Englewood

4.94 out of 5 average rating, 116 reviews

Gulf Side Condo Englewood Florida

A cozy 2 bed 2 bath condo with a full kitchen, dining area, living room, a king size master bedroom and a small 2nd bedroom. The coastal decor and furnishings create the ambiance of an island home. The condo opens onto a wide porch which has beautiful views of the Gulf of Mexico. Wander down the sandy path to a private beach and the turquoise waters of the Gulf. Enjoy sunsets from the porch or the beach. Unwind and let all of your cares float away on the Gulf breezes.

Sep 14 – 21

G$39,878 GYD per night

Home in Englewood

4.96 out of 5 average rating, 104 reviews

Waterfront Cottage by Manasota Key

A 2 bedroom 2 bathroom* waterfront house on Forked Creek in Englewood, Florida 2.5 miles away from Manasota Key. This is a 1,100 sq. ft. single family home on a natural deep water creek with a boat dock. House comes fully furnished and fully equipped. King size and queen size beds in the 2 bedrooms. Full size sofa and IKEA recliners in the "Florida Room", high speed wireless internet and cable and Netflix ready TV, towels, beach chairs, grill, etc. Air mattress is provided.

Sep 12 – 19

G$28,535 GYD per night

Home in Lake Placid

4.86 out of 5 average rating, 112 reviews

Beautiful Home across the street from Lake June!

This property is a 1673 square feet under air, 3 Bedroom, 2 bathroom fully remodeled home w/ 2 car garage and all new furnishing located in Lake Placid across the street from fabulous Lake June (3400 acres) w/ access to a private park w/ BBQ, Playground, & a boat ramp just 300 feet away from the home. The home has 2 twin beds, 2 full size beds, 1 Queen bed. It can host 8 people. It has a pool table, free wi-fi internet access, netflix, and washer/dryer.

Oct 26 – Nov 2

G$33,401 GYD per night

Cottage in Sebring

4.93 out of 5 average rating, 126 reviews

Second Story Bunkhouse

Our Bunkhouse is a quite little get away. My place is close to Sebring, Lake Placid, and Sebring International Raceway. Close to the lake for fishing and several golf courses. You’ll love my place because of we are in a quiet location with a view of the cows and calves. Sometimes the wild turkeys and fox come through. We have recently added an outdoor firepit area. No Smoking or Vaping inside the house. No pets, no animals of any kind. No parties.

Sep 29 – Oct 6

G$15,951 GYD per night

Villa in Englewood

4.92 out of 5 average rating, 111 reviews

Magnificent Waterfront! Kayaks-Pool-Beach! gs

Fantastic Manasota Key Location! Upstairs at Blue Island Inn, waterfront “Seaglass Villa” dazzles with spectacular Bay views! 2 cozy bedrooms; 1 bathroom, kitchen & cozy family room. On-site resort pool overlooks stunning Lemon Bay. 5-minute walk to ocean-side beach or enjoy “Bay-front beach” out back. Quiet island street. low-key quiet respectful vacationers. 1 car parking spot. No visitor parking. No boats. No pets. No smoking. Free use of kayaks!

Oct 20 – 27

G$31,764 GYD per night

Home in Port Charlotte

4.84 out of 5 average rating, 150 reviews

Waterfront property - Cute place

Our home is in small quiet neighborhood and completely ready for your vacation, extended stay, or work away from home. We are located on a canal with a dock with quick access to the Peace River and the intracoastal waterway via boat. There are many local restaurants, activities, and fun things to do. Watch the sunset from your dock or take a 5 minute car ride to Punta Gorda to watch from numerous local restaurants on the water.

Dec 9 – 16

G$26,123 GYD per night

Home in Sebring

4.87 out of 5 average rating, 135 reviews

Comfortable and Convenient

This light and airy open concept design house with a lanai is a comfortable home base for exploring Florida. It is located in the heart of Florida and is less than 2 hours from either coast and Disney attractions. Or, stay home and enjoy Sebring's golf courses, racetrack and many opportunities for fishing and water sports. Highlands Hammocks State Park is nearby for hiking, picnicking and biking.

Oct 8 – 15

G$21,717 GYD per night

Home in Punta Gorda

4.93 out of 5 average rating, 123 reviews

Tropical themed Island style home!

Beautiful tropical theme private home with screened pool/lanai on deep sailboat water. This home has a boat lift that will handle a boat up to 25' and 10,000 pounds - only V-hull style boats - the aluminum walkway dock is elevated beside the boat lift Minutes to Charlotte Harbor by boat. Close to Fisherman's Village. Venice Beach and Fort Myers Beach only 30-40 minutes away.

Apr 6 – 13

G$45,861 GYD per night

Home in Avon Park

4.94 out of 5 average rating, 198 reviews

Lake Letta Lakehouse

This is a great lakefront home on beautiful Lake Letta a 478 acre lake. Face west for beautiful sunsets and great view of undeveloped land nature at it's best. The home is very open and spacious with family room, with wet bar, beautiful stone fireplace, and mid-sized pool table. Xfinity internet is also offered, as well as you tube tv and Amazon Prime streaming packages.

Oct 15 – 22

G$28,635 GYD per night

Vacation rentals for every style

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Popular amenities for DeSoto County family-friendly rentals

Free parking on premises

Air conditioning

Family-friendly home rentals with a hot tub

Home in Port Charlotte

5.0 out of 5 average rating, 74 reviews

Elegant heated pool canal home in very quiet area.

Dec 3 – 10

G$50,083 GYD per night

Apartment in Venice

4.7 out of 5 average rating, 214 reviews

Gulf Getaway, pool, hot tub, kayaking to beach.

Apr 10 – 17

G$31,923 GYD per night

Townhouse in Lake Placid

4.85 out of 5 average rating, 72 reviews

Beautiful Lakefront Townhouse with Pool

Aug 7 – 14

G$31,295 GYD per night

Home in Port Charlotte

5.0 out of 5 average rating, 72 reviews

Myakka River Retreat In Port Charlotte

Dec 4 – 11

G$103,548 GYD per night

Home in Punta Gorda

4.79 out of 5 average rating, 47 reviews

Luxury Home, w/ Pool, Spa, Lanai

Apr 17 – 24

G$39,983 GYD per night

Villa in Rotonda West

4.94 out of 5 average rating, 52 reviews

Shangri-La, full refund*, heated pool, sleeps 6

Jun 2 – 9

G$44,858 GYD per night

Home in Lake Placid

4.95 out of 5 average rating, 38 reviews

Escape to the Lake: Pool, Peaceful & Great Fishing

Dec 17 – 24

G$62,809 GYD per night

Home in Englewood

5.0 out of 5 average rating, 51 reviews

"Peaceful Sol" - large 3 bd, just steps to BEACH!

Feb 5 – 12

G$131,176 GYD per night

Family- and pet-friendly home rentals

Bungalow in Venice

4.9 out of 5 average rating, 78 reviews

Bright, comfy, and near the beach! Kayaks, bikes!

May 8 – 15

G$27,035 GYD per night

Home in Venice

4.63 out of 5 average rating, 104 reviews

Gorgeous House in Venice

May 13 – 20

G$22,050 GYD per night

Home in Englewood

4.85 out of 5 average rating, 52 reviews

Turtle Nest Retreat - Manasota Key (upper unit)

Oct 26 – Nov 2

G$54,503 GYD per night

Home in Punta Gorda

5.0 out of 5 average rating, 8 reviews

Waterfront PGI Heated Pool! Near Fishermen's!

Apr 25 – May 2

G$105,660 GYD per night

Cottage in Englewood

4.77 out of 5 average rating, 73 reviews

Casitas On The Key Directly on Gulf of Mexico #5

Oct 10 – 17

G$45,734 GYD per night

Condo in Englewood

4.89 out of 5 average rating, 55 reviews

Key Condo located on Manasota Key

Aug 26 – Sep 2

G$54,461 GYD per night

Home in Englewood

4.87 out of 5 average rating, 31 reviews

Englewood Cozy Comfy Home B

Oct 11 – 18

G$22,096 GYD per night

Villa in Rotonda West

5.0 out of 5 average rating, 35 reviews

Comfortable 4/2, large pool deck and canal view

Sep 14 – 21

G$54,222 GYD per night

Family-friendly home rentals with a pool

Home in Rotonda West

4.9 out of 5 average rating, 152 reviews

❤ROTONDA RETREAT❤*Spacious*Fully Furnished*Pool*

Oct 24 – 31

G$43,188 GYD per night

Home in Englewood

4.99 out of 5 average rating, 102 reviews

Paradise on the Bay

Nov 21 – 28

G$87,907 GYD per night

Home in Port Charlotte

4.94 out of 5 average rating, 109 reviews

Luxury Bungalo with Pool in Port Charlotte

May 5 – 12

G$28,207 GYD per night

Home in North Port

4.78 out of 5 average rating, 145 reviews

3 bdrm Pool Home / Quiet Cul De Sac

Nov 26 – Dec 3

G$34,890 GYD per night

Home in Sarasota

4.88 out of 5 average rating, 120 reviews

LAKE SARASOTA VACATION HOME Cable! Sport channels!

Apr 24 – May 1

G$54,334 GYD per night

Condo in Englewood

4.89 out of 5 average rating, 54 reviews

Manasota Key Unit 20B across from private beach

Dec 21 – 28

G$35,002 GYD per night

Condo in Placida

4.96 out of 5 average rating, 52 reviews

Beachfront Island Condo w/ Pool &Ferry Service Inc

Oct 31 – Nov 7

G$54,334 GYD per night

Home in Englewood

4.85 out of 5 average rating, 95 reviews

Lemon Bay Luxury 6 BR Villa with Pool&Tennis Court

Aug 23 – 30

G$89,035 GYD per night

Destinations to explore