Vacation rentals in De Soto

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Top-rated vacation rentals in De Soto

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Top guest favorite
A cabin with wooden exterior is surrounded by tall trees and shaded ground. A spacious porch is visible at the front entrance. A calm dog sits on the ground in the foreground, offering a glimpse of the natural tranquility of the setting.
Cabin in Alto Pass
4.99 out of 5 average rating, 317 reviews

Ma's Cabin, Alto Pass, IL. Fine country lodging.

Cute and country remodel done in 2019. Recent new appliances, furnishings, flooring, heat & A/C, washer & dryer. Cabin is secluded and quiet plus 1/2 mile from Alto Pass Lookout Point and right in the middle of many award-winning wineries. 15 miles from Carbondale 4 miles from Giant City 30 miles from Garden of the Gods 6 lakes within 10-mile radius Hundreds of miles of hiking trails in nearby Shawnee National Forest 6 miles from Bald Knob Cross Please, no dogs! No smoking in cabin!

Top guest favorite
A cozy living area is presented, featuring a stone fireplace with a mounted television above. Comfortable seating options include a leather armchair and a soft couch, arranged around a wooden coffee table. Natural light filters in through the window, enhancing the tranquil environment.
Cabin in Makanda
4.98 out of 5 average rating, 165 reviews

Sanctuary Cabin- Hot Tub & Woods

Hi, hello, welcome! We invite you to take it easy at this unique and tranquil getaway. The kitchen is stocked, the hot tub is ready to go, and the local area boasts many wineries, state parks for hiking, and beautiful scenery. This spacious cabin features a comfortable King bed, 55” TV above a gas fireplace, and recently had a top to bottom renovation! The spacious back deck features a large hot tub just steps from the back door, hooks for the provided terry cloth robes, and a Weber grill.

Superhost
Home in De Soto
5 out of 5 average rating, 5 reviews

Awesome House in DeSoto

Welcome to this Awesome Home centrally located in Southern Illinois available for your enjoyment while in the area. Featuring a Large Furnished Kitchen, Livingroom, Laundry Room, Three Fully furnished Bedrooms, including TVs, Two Bathrooms, Large Driveway, Extended Wi-Fi Service, and Large Fenced in Backyard with Secure Gated Access for RV's, with 30-amp Electric Plugs and Water available for slight upcharge. I am personally available to ensure that your check-in and stay is enjoyable.

Top guest favorite
Home in Herrin
4.97 out of 5 average rating, 109 reviews

Charming 3 bedroom retreat

Four friends have joined forces to create this cozy space for you to feel right at home in. We've made the space fun, with each bedroom having a unique theme. Our coffee bar also offers a variety of mugs, so each person can pick their favorite. We had your comfort in mind when we selected new queen mattresses, soft bedding, and plush towels. The couch and extra seating are very comfy. For our likeminded germaphobe friends, we chose light bedding to ensure utmost cleanliness.

Top guest favorite
Cabin in Carbondale
4.97 out of 5 average rating, 89 reviews

Charmful Cabin Artist respite next to refuge

This Veteran owned Charmful Cabin is stocked with fine Art supplies and ready for your creative Oasis. Sip on your favorite cocktail on the balcony or snuggle up next to the fireplace. 1 bedroom, 1 bathroom whole home sanctuary. We are walking distance to the Crab Orchard Wildlife Refuge. A short drive to the Artsy community of Makanda. and an even shorter drive to the food and fun in the college town of Carbondale, LOVE the wine trail? We are aptly located near many wineries.

Top guest favorite
An inviting modern cabin exterior is illuminated at dusk. The deck features outdoor seating with a table and chairs, complemented by a hot tub nearby. Soft lighting outlines the steps, providing a warm glow against the backdrop of a deep blue sky.
Cabin in Pomona
5 out of 5 average rating, 147 reviews

Modern Cabin at Trillium Ridge

Tucked into the rolling hills of the Shawnee National Forest, our modern cabin offers a welcoming retreat where comfort and nature meet. Wander down a private trail to explore or climb at the Holy Boulders, or take an easy drive to local wineries and see the iconic sights of Little Grand Canyon, Inspiration Point, and Pomona Natural Bridge. When you’re ready to slow down, return to soak in the hot tub, unwind in the sauna, and settle into our cabin made for rest and connection.

Top guest favorite
The treehouse is elevated on wooden stilts, surrounded by lush greenery. A wooden deck with a railing extends from the entrance, creating a welcoming outdoor space. Large windows brighten the upper level, while a sun art piece adorns the side of the structure.
Treehouse in Makanda
4.96 out of 5 average rating, 431 reviews

Panthers Inn Treehouse

Come nestle amongst the leaves at Panthers Inn Treehouse. This secluded, well equipped, elevated cabin has the perfect combination of natural beauty and artful luxury. Isolated yet conveniently located 2 minutes from Blue Sky and Feather Hill wineries, within 5 minutes of Panthers Den hiking trail and the Shawnee Hills canopy tour and only 10 min from I-57 exit 40. Panthers Inn is the perfect starting and ending point to your Shawnee Hills Wine Country vacation!

Guest favorite
A cozy living area is furnished with a large sectional sofa and a matching armchair, complemented by decorative cushions. Light filters through window blinds, and a soft area rug covers the hardwood floor. A small table is positioned nearby.
Home in Carbondale
4.86 out of 5 average rating, 314 reviews

Relaxing 3 Bedroom Cottage in Quiet Neighborhood

This happy 3 bedroom duplex will be a family favorite on your next trip to Southern Illinois. You'll enjoy 3 cozy bedrooms each equipped with a TV, 1 bathroom, ample deck space and firepit. We are located on a quiet street within walking distance of all Carbondale has to offer – Downtown Carbondale, restaurants and pubs (.8 miles), the Memorial Hospital of Carbondale (.5 miles), Carbondale Civic Center (.8 miles), Amtrak Station (.9 miles), and SIU (1.1 miles).

Guest favorite
A newly constructed treehouse sits elevated on stilts among tall trees. Wooden stairs lead to an entrance, and the structure features a mix of natural wood siding with a distinct gabled roof. Surrounding greenery adds to the secluded atmosphere of the wooded area.
Treehouse in Carterville
4.91 out of 5 average rating, 34 reviews

Koopers Landing Treehouse

Escape to the pines at Koopers Landing! This newly built treehouse offers a private getaway and a home town feel all in one. You can go for a walk around the wooded 5 acres or sit inside and enjoy the scenery from the huge windows of the treehouse. Sleeps 4-6. Come and enjoy a stay with us at Koopers Landing! We are booking 1 night stays on weekends in January! Just send us an inquiry and we can approve it☺️

Guest favorite
The exterior of a single-story cabin is displayed, featuring a gabled roof and light grey siding. A spacious wooden deck extends alongside the cabin, equipped with two chairs and a welcoming entrance door. Nearby greenery provides a natural backdrop.
Guesthouse in Alto Pass
4.9 out of 5 average rating, 116 reviews

Cabin on the Wine Trail!

This cabin is in the village of Alto Pass, in the Shawnee National Forest and along the Southern IL wine trail. Adjacent to a Victorian home, it is a separate cottage with 2 bedrooms, 1 bathroom, washer/dryer, fully-equipped kitchen, dining/living area, TV (Amazon/wifi), and deck with views of woods and valley. (The couch's foot rests work by plugging in the couch and are in good working condition.)

Top guest favorite
A serene private lake is surrounded by lush trees, reflecting a blue sky. A kayak is on the water, while a small wooden ladder leads to the water's edge. Smooth stones line the shore, creating a peaceful setting for relaxation or water activities.
Cabin in Du Quoin
4.97 out of 5 average rating, 165 reviews

H & B's...Come experience the magic of nature!

The Cabin is nestled in the woods, a few hundred feet from a beautiful private lake. If it's total solitude you are looking for, this is the place. Keyless entry makes it perfect if you want total privacy. If you want lake access, come down and have coffee with us for orientation. Our pantry items, coffee, granola, half & half, and spices are perfect for your full-service kitchen.

Guest favorite
Apartment in Carbondale
4.91 out of 5 average rating, 113 reviews

Modern Queen Suite Near SIU Carbondale

Stay in Suite 3 at Wall Street Suites, a modern queen suite near SIU Carbondale. This newly renovated micro-suite blends industrial charm with stylish urban design. Enjoy a full kitchen, Smart TV, queen bed & updated bath, plus a shared lobby workspace. Perfect for mid-term or monthly stays near SIU East Campus. Note: Access via stairwell.

Popular amenities for De Soto vacation rentals

  1. Airbnb
  2. United States
  3. Illinois
  4. Jackson County
  5. De Soto