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Vacation rentals in Cuipo

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Top-rated vacation rentals in Cuipo

Guests agree: these stays are highly rated for location, cleanliness, and more.

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Top guest favorite
An indoor shower area features a wall of glass block, allowing natural light to filter in. The walls are finished in a smooth concrete texture. Simple wooden shelves hold toiletries, and a showerhead is mounted above a sleek, open shower space.
Guesthouse in El Valle de Antón
4.99 out of 5 average rating, 124 reviews

Spacious Casita with Bamboo View

Walk 20 minutes to the artisan mercado and restaurants on Ruta 71. Cerro Cara Iguana trailhead is walking distance from the casita. High insulated ceilings and 2 ceiling fans for comfort. Private hammock patio for an afternoon nap. Washer/dryer in the casita. Hot water throughout. Kitchen has a 2 burner cooktop, countertop oven, microwave, instant pot, electric skillet, blender and coffee maker. 2 Internet providers and a small workspace available. * No television set * Non smoking property

Guest favorite
A traditional bohio with a thatched roof is set amidst lush greenery. A pathway leads to a serene pool, flanked by vibrant tropical plants and flowers. The surrounding landscape features distant mountains, softly illuminated by the warm light of dusk.
Guesthouse in El Valle de Antón
4.93 out of 5 average rating, 101 reviews

The Retreat in El Valle - Casita del Jardin

Welcome to your serene retreat in El Valle, Panama! Nestled amid lush nature, our two-bedroom casitas offer a peaceful escape with breathtaking views, exotic wildlife, and flora. Each casita features a queen bed, choice of king or twin beds in the second room, a small fridge, coffee station, Wi-Fi, and large terrace. Enjoy the shared pool, meditation and healing sessions by appointment, and explore world-class hiking nearby. Just a short walk to restaurants and El Valle’s famous artisan market!

Top guest favorite
Home in Costa Esmeralda
4.98 out of 5 average rating, 211 reviews

Beach House-Amazing Pool & Jacuzzi - Pet Friendly

Majestic Sands! Come relax with the whole family at this piece of paradise.located in a private beach community in Costa Esmeralda, San Carlos. Few minutes from the Pan-American highway and a few minutes from other local beaches such as Gorgona, and Coronado. It is a 5-minute walk to our beach, or if you prefer you can go by car. The home includes an amazing saltwater pool and hot tub with hammocks with views of amazing palm trees.Uninterruptible power with Smart Home Energy Management Systems.

Top guest favorite
The exterior of the cabin is showcased amidst lush greenery, featuring a sloped roof and large glass windows. A wooden staircase leads up to the entrance, while a stone pathway meanders through the garden, enhancing the natural surroundings.
Cabin in Penonome
4.98 out of 5 average rating, 132 reviews

Aqeel cabin in the nature

Relax at this unique and tranquil getaway surrounded by nature. If you're lucky, you may wake up to see white-faced capuchins from your bedroom window and spot an abundance of birds, such as the crested oropendola or a toucan. The property offers river access with a sandy, beach-like area, and there is a 1 km walking trail alongside the river. With satellite high-speed internet access, you'll stay connected, though the river and sandy area may not be accessible during rainy days.

Guest favorite
A serene swimming pool is depicted surrounded by lush palm trees, with the tranquil sea visible in the background. The water's clear blue tiles reflect the sky and nearby greenery, while the gentle curvature of the pool edge invites relaxation.
Villa in Portobelo
4.96 out of 5 average rating, 84 reviews

Entire Villa with pool in front of beach!

Beautiful spacious 4 bedroom villa right in front of the sea. Enjoy the swimming pool with your family, then take a dip into the sea only steps away. Very pet friendly! Take a boat trip for the day with a local certified tour guide from portobelo town. Every room has full AC, including the living room - but please be conscious of the environment when using ACs. Excellent WiFi ! Open Kitchen, with breakfast included. We can also arrange for lunch - fresh lobster!

Top guest favorite
A balcony is visible with colorful tiled tables and black wrought iron chairs. Lush potted greenery adds a natural touch, while surrounding buildings with terracotta roofs can be seen in the background. The scene is illuminated by daylight, enhancing the vibrant colors.
Loft in Panama
4.99 out of 5 average rating, 174 reviews

Patty’s Casco 2BR Loft | Balcony & Personal Touch

“Feel at home in Casco Viejo—personally welcomed by your hosts, Patty & Rudy.” Stay in the Heart of Casco Viejo with Patty’s Casitas! Prime Casco Viejo Location | Quiet, Convenient & Charming Stay steps from restaurants, cafés, bars, and plazas—right by the El Rey boutique supermarket and the waterfront promenade. This peaceful spot is rare in Casco, tucked away from rooftop noise and perfectly located at the entrance of the neighborhood for easy in & out access!

Top guest favorite
A covered patio area displays a mix of seating options, including two wicker chairs and a small glass-top table surrounded by greenery. A hammock hangs gracefully in the foreground, adding a touch of comfort to this relaxed outdoor setting.
Cottage in El Valle de Antón
4.99 out of 5 average rating, 161 reviews

Casa Campestre Los Macos, El Valle de Antón

🏡 Bienvenidos a Casa Campestre Los Macos, un refugio acogedor ubicado en el corazón verde de El Valle de Antón, dentro de un cráter volcánico extinto, el más grande habitado en el mundo. Es una experiencia de descanso total, en una zona segura y tranquila, ideal para amantes de la naturaleza, el silencio y el aire puro. Despertarás con el canto de los pájaros, disfrutarás una taza de café en el jardín y pasarás tardes familiares en una casa totalmente equipada.

Superhost
A tranquil dipping pool is framed by lush greenery, featuring white loungers and a large umbrella for shade. The pool area exudes a serene vibe with vibrant bougainvillea in the background, enhancing the inviting outdoor space.
Home in Taboga Island
4.94 out of 5 average rating, 216 reviews

Casa Rosie - Dream Home on Tabogá Island

Casa Rosie is a gorgeous villa on Taboga island with an intimate vibe and spectacular views of the ocean. The perfect place for couples, small groups, and families to unwind and make magical memories! . With great wifi, fully equipped kitchen, 3 inviting bedrooms, and a spacious yet personal feel… Casa Rosie is your home away from home. Included in every stay is free pick up and drop off to the ferry terminal - please let us know the details of your arrival.

Guest favorite
Home in Altos del Maria
4.76 out of 5 average rating, 147 reviews

Villa Acuario

Relaxation is guaranteed in this one-of-a-kind glass house nestled in the lush mountains of Altos del María. Surrounded by nature and designed with floor-to-ceiling glass walls on all sides— as if you’re living inside a crystal ball. With no direct neighbors, panoramic forest views, it is perfect for a family getaway, a quiet reset, or an extended stay. The home offers light-filled interiors during the day and unforgettable stargazing nights from the rooftop.

Guest favorite
A spacious outdoor deck features modern furniture arranged for relaxation, overlooking a lush mountainous landscape. Verdant hills and a colorful sky at dawn create a tranquil environment, inviting guests to enjoy the natural beauty and serenity of the surroundings.
Villa in El Copé
4.92 out of 5 average rating, 190 reviews

Mountain retreat

Our beautiful, modern, comfortable house is designed in an eco-friendly manner in harmony with nature. It is an ideal place to relax and also a base to explore the area which is in a beautiful part of Panama near a cloud forest national park with amazing hiking to waterfalls and local communities. The house is large, sleeping 12, within 17 acres of forest with rivers for swimming. We can arrange tours and hosted retreats for yoga, cooking and more.

Top guest favorite
Camper/RV in El Valle de Antón
4.99 out of 5 average rating, 264 reviews

Armadillo Shelter & Garden. Valle de Anton

Es un alojamiento unico y especial que hemos diseñado para que experimentes el Valle de Anton de una forma mas consciente y natural. Es un RV o remolque remodelado, para hacerlo acogedor>funcional y cómodo >estilo tiny house. El espacio tiene una pequeña y completa cocina, agua caliente, wifi, café y te. Se encuentra rodeado por un lindo jardín. Con entrada independiente y un area para estacionar el auto. Es ideal para 1 o 2 personas.

Top guest favorite
A bright dining area features a round wooden table surrounded by six turquoise chairs. Large windows allow natural light to fill the space, showcasing a cozy atmosphere. A wooden dresser and potted plants add touches of comfort. Arched openings lead to other rooms.
Home in El Valle de Antón
4.96 out of 5 average rating, 188 reviews

Rustic family mountain home - 5 min walk to town!

Rustic family home with exquisitely landscaped garden complete with bridge over natural stream. Outdoor chill out space with barbecue and terrace under roof with hammocks on one side of the house, and a pergola with lounge area and gas grill on opposite side of the house. Centrally located to main attractions, only a 7 minute walk to the main market. Peaceful, relaxing refuge surrounded by views of nature and the cloud forest.

Popular amenities for Cuipo vacation rentals

  1. Airbnb
  2. Panama
  3. Colón Province
  4. Cuipo