
Apartment vacation rentals in Colón Province
Find and book unique apartments on Airbnb
Top-rated apartment rentals in Colón Province
Guests agree: these apartments are highly rated for location, cleanliness, and more.

In the heart of Casco, remodeled and with parking
Escape and discover the old town in this remodeled, comfortable and central accommodation in the heart of Casco Viejo. Our location is the best, it will make you come back. Close to restaurants, bars, impressive churches, and museums. The property dates back to the 17th century (1756) history and good atmosphere. You can explore the area on foot, fully equipped kitchen, European king bed, you will feel right at home, surrounded by the famous calicanto walls. -A large living room -Fully-equiped kitchen

Best Location – Fancy Apartment in Casco Viejo
Experience absolute luxury in our fully remodeled loft, with access to a spectacular 360° rooftop terrace, where you'll enjoy breathtaking views of the city and skyline. The building also features an elevator for your convenience. Located right in front of a vibrant plaza with renowned restaurants, the location is truly unbeatable, and security in the area is excellent. Relax in the rooftop, enjoy sunset views from the terrace, and experience the unique charm of Panama’s historic Casco Antiguo

Apto 4 min from Tocumen Airport | 24-hr check-in
Layover in Panama? Stay where everything is easy and comfortable Just 4 minutes from Tocumen International Airport – perfect for early flights or quick stopovers A modern, comfortable, and secure apartment with: • Fast WiFi and air conditioning • Smart lock and flexible check-in • 24/7 security • Pool, gym, and fully equipped kitchen • Steps from the ITSE Metro station Ideal for layover travelers, curious tourists, or business trips. 🌴 Just arrive — everything’s ready for you. We’ll be waiting!

Peaceful Stay in the Heart of Casco
Enjoy a quiet and comfortable apartment in the center of Casco Viejo. It’s a great place to relax after walking around the neighborhood, with everything you need for a nice stay. Restaurants, cafés, and main attractions are just a short walk away. Casco Viejo, UNESCO World Heritage Site, known for its colonial buildings, and iconic streets. Just steps from Fonda Lo Que Hay, ranked among Latin America's Top 50 culinary destinations. Close to MYKA Greek Yogurt and the iconic La Compañía Hotel.

Spacious 4Br Beachside Getaway at Playa Escondida
Escape to Playa Escondida Resort & Marina for the ultimate luxury getaway. Our 4Br beachfront apartment is ideal for families and friends seeking relaxation in the Caribbean Sea. Indulge in plush rooms, white sand beaches, and unforgettable sunsets. Our fully equipped apartment provides everything you need for an exceptional stay, and our unparalleled service ensures you'll never want to leave. Best of all, it's just an hour away from Panama City. Book now for a truly unforgettable experience.

The View of Casco: Designer Loft with best Balcony
Sip your morning coffee or evening wine on the balcony, taking in a stunning, panoramic view of the city skyline! Experience the absolute best of Casco Viejo from this elegant, fully remodeled 1-bedroom loft. Nestled inside a beautifully restored 1850 colonial building—featuring historic, original calicanto walls—this stylish space puts the entire city at your doorstep. You are just steps away from world-class dining, vibrant cafes, museums, and Casco's legendary nightlife

KasaKai Penthouse · Caribbean Sea View· Beachfront
This exclusive beachfront penthouse offers one of the closest true beach experiences from Panama City. Wake up to panoramic Caribbean Sea views, enjoy direct private access to the water, and relax in your own green outdoor area, ideal for quiet moments or private barbecues. Perfect for travelers seeking privacy, comfort, and nature, this penthouse combines a unique feet-in-the-water experience with high-end amenities, creating an unforgettable seaside stay.

Gorgeous Flat in the best location in Casco Viejo
This cute and stylish studio is perfectly located in the heart of Casco Viejo, Panama City’s most charming historic district. Recently renovated, it combines modern comfort with classic charm inside a beautiful colonial building—just steps from top restaurants, bars, monuments, and attractions. The space includes a comfortable sofa bed, making it ideal for a couple or a small family looking to enjoy the vibrant atmosphere of Casco right outside their door.

Beachfront Paradise in a 5-star resort
Perfect vacation in the Panamanian Caribbean. Just 1h from Panama City. This private resort of Arena Blanca and Aguas Turquesa is your closest paradise with Access to Private Islands through Muelle , Pádel , Infinity Pool, Children's Games, Restaurants and Bar . Beautiful and comfortable Apartment with Sea View, Autonomous Access, Spacious Living and Dining Room, Terrace , Full Kitchen, 3 Rooms , 5 beds , 2 Full Bathrooms, A/C and Wifi , 8 guests max .

Private parking & rooftop | Studio Casco Center
This beautiful restored studio from the 1870s blends history with modern design. Enjoy a private rooftop terrace with seating and BBQ, plus private PARKING—ideal after exploring Casco's best restaurants, galleries, and nightlife steps away. ✨ Highlights: - Historic Charm: Original tile floors and exposed colonial stone walls. - Comfort: King bed, living room, and full kitchen. - Amenities: Private rooftop & private PARKING. - Great location

Modern, central and comfortable (104)
Moderno y acogedor estudio en el corazón de Panamá. Perfecto para explorar el Casco Antiguo, la Cinta Costera y más. Cocina completa, cama queen, sofá cama doble, aire acondicionado, WiFi rápido y baño privado. Ideal para 1–4 personas. Acceso privado, ascensor y check-in autónomo. Rodeado de restaurantes, transporte y sitios turísticos. ¡Tu base ideal para conocer la ciudad! 🧳 Estancias largas bienvenidas (descuentos aplicables)

The best view of the Old Town
Welcome to this charming accommodation located in the heart of Casco Viejo, on the third floor facing one of the most iconic squares in Panama, Plaza Catedral! Thanks to its privileged location, you will enjoy a unique view of the square and the imposing Cathedral Church. Right in this lively square, you will have at your disposal a wide variety of restaurants and shops where you can buy souvenirs of this wonderful trip.
Popular amenities for Colón Province apartment rentals
Weekly apartment rentals

Duplex in Casco Antiguo across from the Sofitel

Luxury Centric 2BR Apartment in Casco Viejo

Lovely & Cozy central apartment in Casco Viejo

Luxury Apartment | Walk to Restaurants & Shops

Walk to Everything | Luxury Stay in Casco Viej

Colonial style with calicanto and private balcony

Villas La Fontana Spacious ApartaSuite - Pool 104

Panoramic Casco Viejo Lookout in The Sands
Private apartment rentals

Historic 2BR Loft at Casa del Horno, Old Town

Elegant Apt in Costa del Este. Premium Amenities

Luxury apt in Panama City 2 Rooms 3 Baths

Amazing loft with Casco charm in the best location

Apartment Casco Antiguo Panama I Walk everywhere

Sunrise Caribbean at Playa Escondida Resort & Marina

Cozy Apartment in the Heart of Casco Viejo

811 San Felipe
Apartment rentals with a hot tub

Ocean View - Playa Escondida Resort

New Flat with Ocean + City Views

Ocean View Apt in Panama, Yoo&Arts

Marina House at Playa Escondida Resort

Apartment at Playa Escondida Resort & Marina

Apartment in a hidden beach

Tropical Paradise at Playa Bonita

View and Comfort Apartment with Home Warmth
Destinations to explore
- Rentals with a sauna Colón Province
- Rentals with pools Colón Province
- Guesthouse rentals Colón Province
- Bed and breakfasts Colón Province
- Rentals with a kayak Colón Province
- Rentals with lake access Colón Province
- Family-friendly rentals Colón Province
- House rentals Colón Province
- Pet-friendly rentals Colón Province
- Chalet rentals Colón Province
- Boutique hotels Colón Province
- Nature eco lodge rentals Colón Province
- Private suite rentals Colón Province
- Villa rentals Colón Province
- Condo rentals Colón Province
- Beachfront rentals Colón Province
- Rentals with breakfast Colón Province
- Hostel rentals Colón Province
- Tiny house rentals Colón Province
- Cottage rentals Colón Province
- Townhouse rentals Colón Province
- Waterfront rentals Colón Province
- Serviced apartment rentals Colón Province
- Vacation home rentals Colón Province
- Shipping container rentals Colón Province
- Rentals with a hot tub Colón Province
- Loft rentals Colón Province
- Rentals with beach access Colón Province
- Hotel rooms Colón Province
- Cabin rentals Colón Province
- Ski-in/ski-out rentals Colón Province
- Rentals with an accessible height bed Colón Province
- Apartment rentals Panama
- Things to do Colón Province
- Sightseeing Colón Province
- Sports activities Colón Province
- Nature and outdoors Colón Province
- Food and drink Colón Province
- Tours Colón Province
- Art and culture Colón Province
- Things to do Panama
- Nature and outdoors Panama
- Sports activities Panama
- Sightseeing Panama
- Tours Panama
- Food and drink Panama
- Art and culture Panama





