Apartment vacation rentals in Colón Province

4.96 out of 5 average rating, 254 reviews

In the heart of Casco, remodeled and with parking

Escape and discover the old town in this remodeled, comfortable and central accommodation in the heart of Casco Viejo. Our location is the best, it will make you come back. Close to restaurants, bars, impressive churches, and museums. The property dates back to the 17th century (1756) history and good atmosphere. You can explore the area on foot, fully equipped kitchen, European king bed, you will feel right at home, surrounded by the famous calicanto walls. -A large living room -Fully-equiped kitchen

4.93 out of 5 average rating, 155 reviews

Apto 4 min from Tocumen Airport | 24-hr check-in

Layover in Panama? Stay where everything is easy and comfortable Just 4 minutes from Tocumen International Airport – perfect for early flights or quick stopovers A modern, comfortable, and secure apartment with: • Fast WiFi and air conditioning • Smart lock and flexible check-in • 24/7 security • Pool, gym, and fully equipped kitchen • Steps from the ITSE Metro station Ideal for layover travelers, curious tourists, or business trips. 🌴 Just arrive — everything’s ready for you. We’ll be waiting!

A well-lit dining area features a large wooden table surrounded by upholstered chairs. Exposed wooden beams contrast with the smooth, light-colored walls, creating an open and airy feel. Two sets of shuttered windows allow natural light to enhance the space.

4.89 out of 5 average rating, 141 reviews

Colonial Luxury Apartment – Best Location in Old T

Welcome to our spacious colonial-style apartment, designed to comfortably host up to 8 guests in the heart of Casco Viejo. Located directly across from one of the most beautiful plazas in the historic district, you’ll be surrounded by renowned restaurants, cafés, and vibrant city life. The building features an elevator for your convenience and access to a rooftop terrace with a swimming pool, where you can enjoy stunning views of Casco Antiguo. Its prime location allows you to explore all the

Apartment in Maria Chiquita

A tranquil view of the clear, shallow waters of the Caribbean Sea is displayed, with gentle waves lapping against the shore. Smooth stones are partially visible above the waterline, and a distant mountain range is seen against a backdrop of scattered clouds.

4.95 out of 5 average rating, 141 reviews

Spacious 4Br Beachside Getaway at Playa Escondida

Escape to Playa Escondida Resort & Marina for the ultimate luxury getaway. Our 4Br beachfront apartment is ideal for families and friends seeking relaxation in the Caribbean Sea. Indulge in plush rooms, white sand beaches, and unforgettable sunsets. Our fully equipped apartment provides everything you need for an exceptional stay, and our unparalleled service ensures you'll never want to leave. Best of all, it's just an hour away from Panama City. Book now for a truly unforgettable experience.

4.96 out of 5 average rating, 113 reviews

A spacious living room features a comfortable brown sofa and an armchair beside a decorative coffee table. Natural light enters through large glass doors draped with sheer curtains, illuminating the warm wood floors and elegant decor.

Apartment in Panama City

Luxury Mid-Century Apartment In Casco Viejo

Luxury mid-century one bedroom Boutiqe 72 m2 apartment. Step into the elegant, functional and comfortable place that we offer with love. The apartment located within a beautiful two-floors antique building in the heart of Casco Viejo. The apartment includes a well equipped brand new kitchen, a dining area and a spacious living room, also a balcony with a view of the lively streets below. The tranquil bedroom has an ensuite bathroom and a walking closet that fitting perfectly to your needs.

4.98 out of 5 average rating, 124 reviews

Apartment in Panama City

The View of Casco: Designer Loft with best Balcony

Sip your morning coffee or evening wine on the balcony, taking in a stunning, panoramic view of the city skyline! Experience the absolute best of Casco Viejo from this elegant, fully remodeled 1-bedroom loft. Nestled inside a beautifully restored 1850 colonial building—featuring historic, original calicanto walls—this stylish space puts the entire city at your doorstep. You are just steps away from world-class dining, vibrant cafes, museums, and Casco's legendary nightlife

4.92 out of 5 average rating, 49 reviews

Casco Antiguo Apartment with Balcony & Stone Wall

Elegante apartamento en el corazón de Casco Antiguo. Disfruta de un espacio colonial con paredes de piedra expuesta, iluminación cálida y un encantador balcón con vista a calles vibrantes. Ubicado en Avenida B, a pasos de restaurantes, cafeterías, rooftop bars y lugares históricos. Capacidad para hasta 5 huéspedes. Perfecto para vivir la cultura y energía de Casco Viejo. Debido al ambiente animado del área, puede escucharse ruido nocturno los fines de semana.

Apartment in Juan Gallego

A dining table made of wood is set for four, featuring yellow plates and cups. Green plants are positioned on either side, with a backdrop of the sparkling sea and distant islands visible through an open balcony. The scene conveys a relaxed outdoor dining experience.

4.88 out of 5 average rating, 107 reviews

KasaKai Penthouse · Caribbean Sea View· Beachfront

This exclusive beachfront penthouse offers one of the closest true beach experiences from Panama City. Wake up to panoramic Caribbean Sea views, enjoy direct private access to the water, and relax in your own green outdoor area, ideal for quiet moments or private barbecues. Perfect for travelers seeking privacy, comfort, and nature, this penthouse combines a unique feet-in-the-water experience with high-end amenities, creating an unforgettable seaside stay.

Apartment in Maria Chiquita

A panoramic view showcases the turquoise waters meeting a sandy beach under a clear sky, with palm trees lining the shore. The area features several beachside structures, including pools and relaxation spaces, inviting tranquility and connection with nature.

4.91 out of 5 average rating, 143 reviews

Beachfront Paradise in a 5-star resort

Perfect vacation in the Panamanian Caribbean. Just 1h from Panama City. This private resort of Arena Blanca and Aguas Turquesa is your closest paradise with Access to Private Islands through Muelle , Pádel , Infinity Pool, Children's Games, Restaurants and Bar . Beautiful and comfortable Apartment with Sea View, Autonomous Access, Spacious Living and Dining Room, Terrace , Full Kitchen, 3 Rooms , 5 beds , 2 Full Bathrooms, A/C and Wifi , 8 guests max .

5 out of 5 average rating, 35 reviews

Private parking & rooftop | Studio Casco Center

This beautiful restored studio from the 1870s blends history with modern design. Enjoy a private rooftop terrace with seating and BBQ, plus private PARKING—ideal after exploring Casco's best restaurants, galleries, and nightlife steps away. ✨ Highlights: - Historic Charm: Original tile floors and exposed colonial stone walls. - Comfort: King bed, living room, and full kitchen. - Amenities: Private rooftop & private PARKING. - Great location

4.93 out of 5 average rating, 120 reviews

A cozy sitting area is highlighted by a large window offering views of the vibrant plaza and cathedral. Two comfortable armchairs are positioned beside a small coffee table on a textured rug. Natural light fills the space, enhancing the warm tones of the wooden floor.

Apartment in Panama City

The best view of the Old Town

Welcome to this charming accommodation located in the heart of Casco Viejo, on the third floor facing one of the most iconic squares in Panama, Plaza Catedral! Thanks to its privileged location, you will enjoy a unique view of the square and the imposing Cathedral Church. Right in this lively square, you will have at your disposal a wide variety of restaurants and shops where you can buy souvenirs of this wonderful trip.