Colleton County vacation rentals

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Top-rated vacation rentals in Colleton County

Guests agree: these vacation rentals are highly rated for location, cleanliness, and more.

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Guest favorite

Barn in Early Branch

5.0 out of 5 average rating, 103 reviews

Unique escape! 7 acres of woodsy paradise

Escape to Grays Inn - a peaceful and private setting located in the beautiful South Carolina Low Country! 7 acres all to yourself with woods surrounding the spacious yet cozy barndominium. Ideal for visiting hunters 🦌 , stargazers 💫 , tourists 📸 , golfers 🏌️‍♂️, or anyone desiring a peaceful escape🌲. Clean, newly renovated and furnished with unique decor. Secluded community not far from wildlife management areas, The Congaree Golf Club, and convenient enough for day trips to Low Country hotspots.

Jun 1 – 8

G$23,339 GYD per night

Guest favorite

Guest suite in Beaufort

4.96 out of 5 average rating, 510 reviews

Shady Rest #1 near historic downtown Beaufort

Nestled among oaks, this secure, private suite is attached to our home with a separate entrance. We're close to great views, restaurants and shopping, family-friendly activities, nightlife, and the beach. You’ll love our place because of the coziness, the views, and especially the location. It's about a mile from downtown Beaufort, adjacent to the Spanish Moss Biking and Hiking Trail, 6 miles from Parris Island MCRD, convenient to Hilton Head Island, and halfway between Charleston and Savannah.

Oct 27 – Nov 3

G$26,298 GYD per night

Guest favorite

Guesthouse in Beaufort

4.96 out of 5 average rating, 208 reviews

Sunset River House

Our quaint little River House rests on the beautifully natural marsh grass banks of the Whale Branch River in a quiet rural neighborhood. It is located only 9 miles from Historic Downtown Beaufort and 15 miles from Parris Island Marine Corps Recruit Depot. Hunting Island State Park's sandy beaches, nature tails, and lighthouse tours are a scenic 40 minute drive away. You can swim, fish, kayak or go boating right from the dock in our own back yard. When you arrive; you won't want to leave!

Dec 22 – 29

G$22,330 GYD per night

Guest favorite

Guesthouse in Beaufort

4.96 out of 5 average rating, 198 reviews

Spacious Carriage House with Pool & King Bed

Forget your worries in this serene space. Located on 5-acres of secluded wooded land with extensive gardens. This quiet space is on the second floor above a detached garage. The spacious area has just been refurbished: includes a kitchenette and bathroom. Private entry through gated courtyard. Central HVAC; new King bed and TV; Private pool exclusively for guests. LGBTQ welcome. Driving times: 25 min. to Hunting Is. St. Park and Parris Island; 15 min. to historic downtown Beaufort.

Feb 8 – 15

G$23,898 GYD per night

Guest favorite

Guesthouse in Beaufort

4.98 out of 5 average rating, 196 reviews

Buddy's Cottage near everything in Beaufort, SC

Who is Buddy? He was our black Labrador of 12 years. You'll see his photo as you enter. This brand new guest cottage has a private bedroom, 1 full bathroom, a sleeper sofa , 2 TV's, a full kitchen and all the amenities of home. Downtown Beaufort is 2 miles away, Parris Island is less than 5 miles away. In a quiet neighborhood. Are coming for a fishing trip and bringing your boat? Come stay with us , we have room for your boat. You can flush your engine and rinse your boat down.

Aug 27 – Sep 3

G$27,041 GYD per night

Guest favorite

Guest suite in Ehrhardt

4.95 out of 5 average rating, 158 reviews

Lazy Dog Acres Bridal Suite!

Relax by one of the 2 ponds with water features or on the patio. Take a walk around the pond with Isaac or Isabella (Great Danes)as your guide on our 13 acres. Sorry no pets allowed! There is a a micro, fridge & coffee mkr in ur suite. Cook your meal in our shared kitchen. All linens are sanitized w/ high temp sanitizing wash. You have your own private entrance so come and go as you please! Airbnb designated parking. I live on the 2nd floor should u need assistance !

Sep 5 – 12

G$24,935 GYD per night

Guest favorite

Apartment in Beaufort

4.98 out of 5 average rating, 251 reviews

Lady's Island Cottage

Our spacious one-room studio apartment is attached to our home but offers complete privacy. Guests have their own private entrance and parking spot in driveway. The accommodation is not shared with the hosts, however we live on the property. We are located on Lady's Island, SC which is a 20 minute drive to Hunting Island Beach, Parris Island, and MCAS, as well as Historic Downtown Beaufort.The apartment is located in a peaceful residential neighborhood.

Oct 4 – 11

G$21,599 GYD per night

Guest favorite

Apartment in Summerville

4.91 out of 5 average rating, 153 reviews

Full Kitchen, 2 Bed, 2 Bath W/ Laundry & Fish Pond

Hosted by a Superhost with multiple listings in Summerville, this charming, two bedroom, two bathroom apartment features a full kitchen, a washer/dryer combo, and a picturesque 1 acre fishing pond. Resting on a small farm on the outskirts of Summerville, this one-of-a-kind shabby-chic suite will have you in a southern state of mind in no time. Just don't be surprised if you see a chicken or two running around...

Oct 15 – 22

G$24,030 GYD per night

Guest favorite

Bungalow in Beaufort

4.97 out of 5 average rating, 157 reviews

Vintage Cottage near downtown Beaufort

Vintage Cottage at Pigeon Point Enjoy your visit to historic Beaufort with a stay at Vintage Cottage. Walk or bike to downtown shops, restaurants,pubs, churches and riverfront festivals. Stop along the way for ice cream, dessert, coffee or a glass of wine and view the beautiful antebellum homes along the riverfront. Be sure to include a guided carriage ride thru the historic district in your visit!

Oct 28 – Nov 4

G$34,646 GYD per night

Guest favorite

Tiny home in Ravenel

4.9 out of 5 average rating, 484 reviews

CHARLESTON TINY HOUSE ON A GOAT MICRO-FARM

**FRESH UPDATES FOR 2023** Charming, award-winning Tiny House minutes from Historic Charleston and beaches! Collect the eggs, feed the goats, sit by the fire pit under the stars! Escape the hustle and bustle! Come relax with us close to the action yet worlds apart! **We prefer a 2 night weekend stay but if you see one night available, message me and we will get you booked!**

Oct 30 – Nov 6

G$14,915 GYD per night

Guest favorite

Cottage in Saint Helena Island

4.88 out of 5 average rating, 152 reviews

Cute Cottage Next to Hunting Island.

Lovely 1-bedroom 1 bath cottage surrounded by 3 acres of quite peaceful lot. Ideal for a couple, or family with kids. Located short distance (0.4miles) from Coffin Point beach. Cottage has queen bedroom, futon bed, bathroom, kitchen, laundry, Wi-Fi, 2 smart TVs, Disney and Hulu included. You have everything you need to enjoy the nature, and outdoor activities.

Feb 15 – 22

G$30,445 GYD per night

Guest favorite

Tiny home in Beaufort

4.93 out of 5 average rating, 285 reviews

Belle of Beaufort a Luxury Tiny Home with king bed

Ever wonder what this whole tiny house movement is about? This is your chance to enjoy a luxury tiny house experience! Located on Lady's Island in Beaufort, SC, we are just 2 miles from the historic downtown waterfront, and less than 10 minutes to Parris Island. Easy access to Hunting Island State Park and beaches.

Sep 24 – Oct 1

G$22,442 GYD per night