Vacation rentals in Cherokee

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Top-rated vacation rentals in Cherokee

Guests agree: these stays are highly rated for location, cleanliness, and more.

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Top guest favorite

A cozy bedroom features a spacious bed adorned with layered pillows and a light-colored throw. Two bedside lamps provide soft illumination on either side. A dresser in a calming blue hue is positioned against the wall, complemented by a decorative mirror and a potted plant.

Apartment in Johnson City

5 out of 5 average rating, 8 reviews

Fox Den Retreat

Tucked away in a peaceful setting, Fox Den is the perfect blend of cozy charm and moody style. Whether you're house hunting, traveling for work, or simply in need of a serene escape, we’d love to host you. Our thoughtfully designed 1-bedroom, 1-bath apartment home offers everything you need for a comfortable, relaxing stay. On-site coin laundry is conveniently just steps away. Conveniently located 0.8 miles from JC Medical Center, 3 miles from ETSU, and 5 miles from a variety of restaurants.

Top guest favorite

A cozy sleeping area features a full bed adorned with a quilt and decorative pillows. Soft lighting from string lights enhances the calming pastel walls. A charming wooden sign reading 'Johnson City' is displayed, with a view of the private bathroom visible in the background.

Guesthouse in Johnson City

4.95 out of 5 average rating, 204 reviews

Cozy Private Studio- Private Entrance

Enjoy a private studio featuring a comfy full bed with plush linens, Temperpedic pillow and blackout curtains. You have your own private bathroom and private entrance with 24/7 keypad entry. Enjoy a workspace with fast WiFi, microwave, fridge & free snacks. Right across the street from ETSU. You'll love being a mere 1 minute drive/5 minute walk from Timber! upscale dining and Tennessee Hills Brewstillery. A lovely walk to downtown Johnson City via the Historic Tree Streets’ tree-lined streets.

Top guest favorite

A comfortable living area features an Italian leather couch and chair, arranged around a coffee table. A vibrant area rug with a geometric pattern sits beneath. Soft lighting is provided by a floor lamp beside the couch, and a framed artwork of a highland cow adorns the wall.

Loft in Johnson City

4.93 out of 5 average rating, 198 reviews

PET Friendly! Quiet and Cozy Newton’s Nest Unit#1

Beautiful duplex located minutes away from East TN State University, Johnson City Medical Center, and both downtown JC and Jonesborough. Newly renovated !! Fresh paint, new appliances, doors, and more! Contains a unique, stunning loft area that adds so much beauty and character to the home. For any questions regarding booking, additional pictures, or renovations please feel free to contact us! We are so excited to potentially have you in this home away from home! Contact us at 423-676-3956

Guest favorite

The exterior of the apartment features a welcoming green door and a small pathway lined with white stones. A grill is positioned on the patio, surrounded by lush greenery and flowering plants. A picnic table is visible nearby, offering an outdoor dining option.

Apartment in Johnson City

4.87 out of 5 average rating, 77 reviews

Apartment in Tree Streets, great location

Enjoy this quaint 1 BR apartment in a family neighborhood in the Tree Streets historic district. The space is newly renovated, full of light, and is completely private and quiet - with an extra sleeper sofa. On the second floor. A short walk to the heart of JC or to the ETSU campus. This space is perfect for a single person, or a couple traveling with or without a child, and has everything you need to settle in for a night or two, or a week or two. Easy in, easy out. Private patio and grill.

Top guest favorite

The living area features a cozy seating arrangement with a dark sofa and two gray armchairs. A round wooden coffee table is centered on a textured area rug. Exposed brick walls add character, complemented by wall art and a flat-screen TV.

Apartment in Johnson City

4.97 out of 5 average rating, 74 reviews

Chic 1 B/1 B Downtown Johnson City w/parking

Chic Downtown Loft in Johnson City, TN w/ Parking WELCOME to Suite310, a 1 bed, 1 bath that offers the perfect blend of comfort and sophistication. Leave your car parked in the private lot and enjoy your proximity to trendy restaurants, lively bars, coffee shops and charming boutiques. Enjoy the private entrance and elevator up to a modern space with keyless entry, Wi-Fi, 2 TVs, YouTube TV app included & in-unit laundry. Business or pleasure, you'll find everything for a memorable visit.

Top guest favorite

A spacious living room is showcased, featuring a comfortable sofa adorned with decorative pillows and textured throws. Two accent chairs in vibrant yellow add a pop of color, while a patterned area rug enhances the room's warmth. Framed landscape artwork is displayed above the sofa.

Condo in Johnson City

4.99 out of 5 average rating, 154 reviews

Dog & Kid Friendly+1 King & 2 Queen Beds+Location

Welcome to our charming home, thoughtfully designed to provide everything you need for an ideal visit to Johnson City. The space features a relaxing open living room, plus a built-in dog room, where you & your loved ones will create unforgettable moments. Dine & enjoy time together over a meal cooked in the fully stocked Kitchen. Two comfortable bedrooms offer a retreat to relax & unwind after exploring our beautiful area. Wake with a smile & enjoy our thoughtfully supplied coffee & tea bar.

Top guest favorite

A vintage 1966 Streamline Camper is situated on a gravel area, surrounded by natural landscapes. A wooden picnic table is positioned nearby, accompanied by decorative plants. String lights are draped above, creating a relaxed outdoor atmosphere under a clear blue sky.

Camper/RV in Jonesborough

4.97 out of 5 average rating, 39 reviews

The Countess

Enjoy the rustic setting of this romantic spot in nature in the heart of the Appalachian Mountains. Pick your wildflowers, feed the sheep, and make your own campfires, all while enjoying the luxuries this vintage 1966 Streamline Camper has to offer. Enjoy hiking the local Appalachian Mountains, plan a visit to the Biltmore Estate, and explore Jonesborough - Tennessee’s oldest (and possibly most charming) town. Conveniently located 7 minutes from Jonesborough and 8 minutes from Johnson City.

Top guest favorite

The image showcases a vintage camper positioned beneath a covered wooden structure. Two decorative chairs are situated around a fire pit made of natural stones, surrounded by mulch. Lush greenery and trees provide a tranquil outdoor setting.

Camper/RV in Unicoi

4.95 out of 5 average rating, 214 reviews

1955 Restored Vintage Aljoa Camper "Nellie Belle"

Blackberry Blossom Farm is often referred to as " A magical place, BEST Airbnb we've ever been to!" The Nellie Belle vintage 1955 Aljoa Camper overlooking the Unaka Mts. is cute as a button! Bathroom accommodations are at our super clean Campground Bathhouse, located beside the Nellie Belle camper. Vintage decorated, clean, 1 comfortable full foam mattress bed, outdoor kitchenette on covered deck, dining table, chairs, fire pit. 100 acre farm, cool, clean air and gorgeous mountain view.

Top guest favorite

A serene creek runs through the landscape, featuring gently flowing water beside lush green grass and trees. A large rock sits near the water's edge, framed by a backdrop of distant mountains under a clear blue sky.

Home in Johnson City

4.98 out of 5 average rating, 141 reviews

Creekside Charmer near I-26 w/ POOL TABLE

Take it easy at this unique and tranquil getaway. Easy convenience to everything just two minutes to I-26. 8 minutes to ETSU and 10 minutes to Johnson City mall area. 40 minutes to Asheville NC and 30 minutes to Bristol Motor Speedway. Visit the new Hard Rock Casino. Enjoy a romantic getaway for just the two of you or bring the family and friends. Enjoy dinner by the creek and roast marshmallows by the fire. Beautiful Mountain View’s. Enjoy the Pool Table for great entertainment.

Top guest favorite

The living area features a pair of green sofas adorned with decorative pillows, set against a light wall. A dark trunk serves as a coffee table, while a vibrant floral artwork is displayed above. Two standing lamps provide additional lighting, enhancing the relaxing environment.

Home in Johnson City

4.98 out of 5 average rating, 141 reviews

Art Haven Unit 2

Close to everything! Remodeled one level duplex w/king bed. LOVE ART? This unit is filled with original art available for purchase. Walk to Dunkin Donuts for your morning coffee or use the Keurig provided. Located on the Medtech Pkwy walking trail which spans 3.5 miles. Close to everything, ETSU, Milligan College, Johnson City Medical Center/Mountain States, Franklin Woods Hospital, Bristol Motor Speedway, Jonesborough, Winged Dear Park, and many more attractions.

Guest favorite

An open living area features a vibrant blue sofa and stylish armchairs arranged around a patterned area rug. A dining table with black chairs complements the space. Natural light streams through the large window, illuminating the neutral-toned walls and modern decor.

Guesthouse in Johnson City

4.95 out of 5 average rating, 113 reviews

Teal We Meet Again

This garage apartment is situated on 2.5 acres of tree bordered land. We have lovely views and quiet surroundings, but our central location make it quick and easy to get anywhere in the Tri-Cities (less than 1 mile from ETSU). Decorated with items that show our love for ETSU, Johnson City and travel, we want you to be comfortable and relaxed. Guests can also enjoy the quiet backyard and patio for a bit of fresh mountain air and relaxation! Great for families!

Guest favorite

A spacious living area features exposed brick walls and hardwood flooring. Multiple seating options, including a leather sofa and armchairs, provide comfort. Natural light floods in through large windows, accented by light-colored curtains. A decorative pouf and indoor plants enhance the welcoming atmosphere.

Loft in Johnson City

4.93 out of 5 average rating, 204 reviews

Spacious 2 Bed Loft in Johnson City

Welcome to your sanctuary in Johnson City, TN. - Spacious 2 Bed 2 Bath loft with a king bed and bunk bed. - Cozy atmosphere with hardwoods and exposed brick. - Stocked kitchen and bathrooms for a home-away-from-home experience. - Laundry room with washer and dryer. - Explore nearby attractions like Founder's Park and The Tweetsie Trail. - We stock the space with little extras and everything you need for a home-away-from-home experience.