Boutique hotel vacation rentals in Cambridge

Find and book unique boutique hotel rentals on Airbnb

Top-rated boutique hotel rentals in Cambridge

Guests agree: these boutique hotel rentals are highly rated for location, cleanliness, and more.

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Hotel room in Cambridge
New place to stay

Modern Cambridge Stay | Near MIT & Harvard

You’ll be at the heart of Cambridge with stunning Charles River vistas, immersed in culture with MIT and Harvard nearby, steps from Inman Square’s shops, and a short walk to Faneuil Hall and Boston's top attractions. Step into our luxurious retreat and soak in the comfort and style. Enjoy a dip in our indoor pool under a breathtaking glass atrium roof. Keep up with your routine in our top-notch fitness center, or treat your taste buds at our on-site restaurant. Perfect for your Cambridge explorations or college visits, this we’ll be your cozy home base. From your spacious room or suite, marvel at the iconic Charles River and Boston skyline views. PLEASE NOTE: This listing is specifically for a hotel room located within a hotel, distinguishing it from typical residential or apartment accommodations. - The property requires a damage deposit of $75/day/unit on the credit/debit card provided. The deposit is required for EACH UNIT and is refunded IN FULL upon check-out. - A mandatory resort fee of $26/night/unit plus tax will be collected upon arrival. The resort fee includes fitness center access, Wi-Fi, 2 in-room bottled waters, in-room coffee & tea, $10 daily food & nonalcoholic beverage credit, free local calls, indoor pool. Please note that the resort fee is not included in the daily rate. - Early check-in is subject to availability upon arrival. - Following property rules, the minimum age required for check-in is 21 years old. Please ensure you have a valid ID for check-in, as it is mandatory for entry. We're delighted you're considering RoomPick’s curated selection of boutique hotels, condo hotels, and resorts worldwide. This room comes with: THE SPACE This 250sf King - City View features: - 1 King bed; - City views; - Coffee maker, mini fridge; - Flat-screen TV; - Work desk; - All linens, towels, and bathroom essentials are provided. You don’t need to bring a thing!! THE PROPERTY Our family-friendly property provides the following on-site amenities: - 24/7 Front desk and Security; - Indoor swimming pool; - Loungers, umbrellas, and towels by the pool; - On-site restaurant; - Fitness center; - Business center; - ATM/cash machine on site; - Rollaway beds are available for an additional fee of $20; PARKING Private parking is available (parking slot reservation is not required in advance) and costs USD 42 per day. PET POLICY Pets are allowed for an additional fee of $75. Up to two pets are permitted per suite. Please ensure you have a valid ID for check-in, as it is mandatory for entry.

Guest favorite
Hotel room in Coolidge Corner
4.93 out of 5 average rating, 30 reviews

Longwood Area | Perfect for Long Stays & Visits

Stay in a charming 1886 Victorian home in the heart of Brookline, Boston. Perfect for long stays, with cozy parlors and timeless charm. 🏡 Location & Accessibility Public Transport Nearby: Just a block from Saint Mary's Street Station, offering easy access to downtown Boston and surrounding areas. Restaurants & Local Shops: The vibrant Coolidge Corner neighborhood is only about 1 mile. Museums & Cultural Attractions: Fenway Park, Boston’s iconic baseball stadium, is about 1.2 miles away.

A well-lit bedroom features a modern wooden bed with a white bedding set. Colorful wall art adds visual interest above the bed. Nightstands with lamps are positioned on either side, and a flat-screen TV is mounted on the wall. Air conditioning and light wood flooring complete the space.
Hotel room in Winthrop
4.88 out of 5 average rating, 34 reviews

(S300) Winthrop Boutique Hotel Airbnb

🌊 Welcome to Winthrop! Discover the charm of this quaint seaside town just minutes from downtown Boston. From your doorstep, you can stroll to 🏖️ serene beaches, 🌳 scenic parks, and cozy local eateries that capture the spirit of New England’s coast. Whether you’re seeking a peaceful retreat by the ocean or planning to explore Boston’s historic landmarks, vibrant neighborhoods, and world-class dining, ✨ Enjoy the calm of the shoreline with the convenience of quick access to the city.

Superhost
A studio room features a queen bed with white linens and blue accent pillows. A blue sofa bed offers additional seating and sleeping space. A small dining table for two is set by a large arched window that allows natural light to brighten the space.
Hotel room in Winthrop
4.6 out of 5 average rating, 15 reviews

(S304) - Cozy Studio Retreat with Parking

🌊 Welcome to Winthrop! Discover the charm of this quaint seaside town just minutes from downtown Boston. From your doorstep, you can stroll to 🏖️ serene beaches, 🌳 scenic parks, and cozy local eateries that capture the spirit of New England’s coast. Whether you’re seeking a peaceful retreat by the ocean or planning to explore Boston’s historic landmarks, vibrant neighborhoods, and world-class dining, ✨ Enjoy the calm of the shoreline with the convenience of quick access to the city.

The room features two double beds with white linens and decorative pillows against a muted grey wall. A warm wooden floor extends throughout the space. Wall-mounted lights provide illumination, and a piece of framed artwork adds visual interest. A door on the far side leads to a hallway.
Hotel room in Woburn
4.75 out of 5 average rating, 4 reviews

Getaway with Friends! 3 Units Close to Downtown!

Just minutes from the hustle and bustle of downtown Boston, this property offers a convenient, budget-friendly stay in the Boston area. Head to the nearby Stone Zoo or the Liberty Ride Trolley Tour for a fun day with the family. If you’re visiting the area for a campus visit, MIT, Harvard, Tufts, Boston University, and several other schools are just minutes away. Close to all the action, but away from the crowds, this property is a great choice for your Boston area getaway!

Guest favorite
A deluxe king room features a spacious bed with a neutral-colored bedspread. A bar area equipped with a microwave, fridge, and sink is located to the left. Light walls are complemented by elegant sconces, while natural wood flooring adds warmth.
Hotel room in Aggasiz - Harvard University
4.88 out of 5 average rating, 59 reviews

Prentiss House by Thatch | Deluxe King #8

Prentiss House by Thatch is a 20-room boutique hotel nestled between Harvard and Porter Square in an iconic Cambridge neighborhood setting. Built in 1843 and renovated in 2022, the building’s rich architecture is complimented by modern amenities and fresh design, providing an upscale yet laid-back atmosphere. Using state of the art technology, roaming staff and a virtual front desk, most guests enjoy their stay without ever needing assistance from our staff.

A standard room features a full size bed with textured bedding and a decorative pillow. Wooden bedside tables and a sleek headboard complement the warm color palette. Framed artwork adorns the wall above the bed. The bathroom is visible through an open door, showcasing modern fixtures.
Hotel room in Back Bay
4.77 out of 5 average rating, 90 reviews

A Boutique Hotel Room in Copley, Charlesmark Hotel

Originally built in 1886 as a private residence in the heart of Boston's Back Bay neighborhood, the hotel has been completely renovated. Our European style boutique hotel features a hip cocktail lounge with an outdoor patio. (Lounge currently unavailable) Premier location. Exceptional value. European ambiance. The Charlesmark combines it all to create a memorable lodging experience. Ambiance - Genuine, Intimate Service

A spacious living area is defined by large windows allowing ample natural light. A comfortable sofa faces a television, while a round coffee table is centered on a textured rug. A dining table with black chairs is positioned nearby, accented by decorative items.
Hotel room in Cambridgeport
4.74 out of 5 average rating, 43 reviews

Sonder 907 Main | Stellar King Suite+ w/ Balcony

Welcome to 907 Main, a gorgeous brownstone in the heart of historic Central Square. Each space features an airy warmth with large windows and hints of exposed brick. Arriving early? We’ve provided luggage storage in the lobby. When you’re ready to explore, head to Massachusetts Avenue for local boutiques, eclectic restaurants, and buzzing taverns. And no matter where your curiosity leads, it all begins at 907 Main.

A spacious room features two large beds dressed in crisp white linens, complemented by a decorative throw pillow. Natural light filters through sheer curtains, illuminating a cozy seating area with a modern couch and accent lamp. A flat-screen TV is mounted above a dark wooden dresser.
Hotel room in West End

The Whitney Boston, Classic Double Queen

The newly-opened Whitney rocks a classic brick townhouse vibe in lovely Beacon Hill, with thoughtful perks like house bikes and a Mediterranean-inspired restaurant, starring creative, seasonally-driven menus. Your room charge will be paid prior to your arrival. The remaining balance of taxes (14.95%) will be charged upon arrival. A refundable security deposit of $XX will also be collected.

Superhost
The exterior of the Harborside Inn is displayed at dusk, showcasing its robust stone facade and illuminated signage. Outdoor seating is visible on the patio, accompanied by bright lights. The contemporary design integrates seamlessly with the historic architecture, providing a welcoming entrance.
Hotel room in Financial District
4.86 out of 5 average rating, 166 reviews

Harborside Inn-Boutique Hotel

Originally built in 1846 as a mercantile shipping warehouse on the Boston Harbor. Here, a modern design with a nautical theme is accented with the latest high technology amenities to satisfy the most savvy business or leisure traveler. Premier location. Exceptional value. Stylish decor. The Harborside Inn combines it all to create a unique lodging experience.

A compact hotel room is presented, featuring a queen bed with crisp white linens. A small desk with a laptop and a chair are positioned beside the bed. A large mirror reflects the room, and built-in cabinetry enhances the functional design.
Hotel room in Back Bay

Welcoming Room in the Heart of Boston's History

Explore historic Boston from our ideal location in Back Bay. Enjoy nearby elite shopping, fine dining, and arts, with the Boston Common and Public Garden close by. The charm of Beacon Hill and the buzz of the Theater District are just a short walk away. All major landmarks, including the Freedom Trail, are less than a mile from our doorstep.

Top guest favorite
A well-appointed sleeping area features a queen size bed dressed with crisp linens and two fluffy pillows. A piece of colorful artwork adorns the wall above the headboard, while natural light filters through a nearby window, accompanied by patterned curtains. A bedside lamp provides additional lighting.
Hotel room in Cambridge
4.93 out of 5 average rating, 61 reviews

(SQ) Perfect WFH set up in Harvard/MIT

Enjoy this Victorian era house built in 1867 with modern amenities. This is a simply decorated WFH-style room with private bathroom consist of one queen size bed, a study desk, and a mini fridge. Comes with linen and shower towel/person, shared common areas include living room, dining room, and kitchen; high speed WiFi.

Popular amenities for Cambridge boutique hotel rentals

When is the best time to visit Cambridge?

MonthJanFebMarAprMayJunJulAugSepOctNovDec
Avg. priceG$28,450 GYDG$32,844 GYDG$38,283 GYDG$41,211 GYDG$42,257 GYDG$34,308 GYDG$46,860 GYDG$50,416 GYDG$69,243 GYDG$61,712 GYDG$39,329 GYDG$29,496 GYD
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Quick stats about boutique hotel rentals in Cambridge

  • Total vacation rentals

    Explore 40 vacation rentals in Cambridge

  • Nightly prices starting at

    Cambridge vacation rentals start at G$10,460 GYD per night before taxes and fees

  • Verified guest reviews

    Over 2,130 verified reviews to help you choose

  • Rentals with dedicated workspaces

    30 properties have a dedicated workspace

  • Wi-Fi availability

    40 of Cambridge vacation rentals include wi-fi access

  • Popular amenities for guests

    Guests love Kitchen, Wifi, and Pool across Cambridge rentals

  • 4.8 Average rating

    Cambridge stays are highly rated by guests—averaging 4.8 out of 5!

  • Nearby attractions

    Cambridge's top spots, include Boston Common, Boston Public Garden, and Harvard University

Destinations to explore