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Vacation rentals in Barro Colorado Island

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Top-rated vacation rentals in Barro Colorado Island

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Top guest favorite
Apartment in Panamá
4.93 out of 5 average rating, 101 reviews

Apto 4 min from Tocumen Airport | 24-hr check-in

Layover in Panama? Stay where everything is easy and comfortable Just 4 minutes from Tocumen International Airport – perfect for early flights or quick stopovers A modern, comfortable, and secure apartment with: • Fast WiFi and air conditioning • Smart lock and flexible check-in • 24/7 security • Pool, gym, and fully equipped kitchen • Steps from the ITSE Metro station Ideal for layover travelers, curious tourists, or business trips. 🌴 Just arrive — everything’s ready for you. We’ll be waiting!

Guest favorite
An open-concept loft is showcased with a high, sloped ceiling and large windows that invite natural light. Comfortable seating is arranged around a glass table, while a dining area and a cozy sleeping space can be seen in the background. Nature views are visible through the windows.
Home in Santa Rita Arriba
5 out of 5 average rating, 8 reviews

The Bird's Nest in the Clouds

Escape to the Clouds: A Nature Lover’s Retreat. Welcome to The Bird's Nest, a serene loft in Santa Rita Arriba, Colón, 50 minutes from the city. Perched in the mountains, this open-concept space offers breathtaking views, fresh breezes, and the sounds of nature - rain and birds. Sleep with doors open, no AC. Perfect for nature lovers, not for those needing silence or climate control. Pool with breathtaking view, wifi and modern comforts included. PLEASE READ ENTIRE DESCRIPTION BEFORE BOOKING.

Guest favorite
The image captures a serene beach scene featuring a sandy shoreline and clear turquoise waters. Thatched-roof gazebos are visible near the water, alongside a wooden pier extending into the sea. Various boats are moored in the distance, surrounded by tropical greenery.
Vacation home in Maria Chiquita
4.91 out of 5 average rating, 67 reviews

Dreamy, Modern Caribbean Home at Playa Escondida

Have fun with the whole family at Casa Capri, a dreamy place which is a perfect fit both for adults & kids. The apartment is at Playa Escondida, a stylish resort with white sand beaches and crystal clear ocean water, several amenities such as a restaurant (with a broad range of great food, including fresh seafood and sushi!), pools to chill or swim, plus fantastic and diverse children playgrounds. Whether you'd like to have a resting vacation or a fun getaway, Casa Capri got you covered. Enjoy!

Top guest favorite
A charming apartment building is nestled among lush greenery and tall trees. The exterior features a welcoming porch with railings and is surrounded by tropical plants, creating a serene environment. Natural sunlight filters through the leaves, highlighting the vibrant foliage.
Guesthouse in Gamboa
4.94 out of 5 average rating, 80 reviews

Gamboa Toucan Apartment casa # 126

Welcome to Gamboa! Only 35 minutes from downtown Panama, Gamboa. Situated in Soberanía National Park and on the shores of the Panama Canal, is a Mecca for Birdwatchers and Nature enthusiasts! Watch the wildlife right from the backyard of your fully equipped apartment. Feel the magic songs of thousands of birds welcoming the twilight of sunrise and dusk in this century old community. Easily explore wildlife on trials through the surrounding old growth jungle and by boat on the Panama Canal.

Guest favorite
A scenic view is presented from the balcony, showcasing lush greenery and the town of Gamboa. The Panama Canal and distant hills are visible under a bright sky filled with clouds. A hummingbird feeder is hung nearby, attracting local wildlife.
Cottage in Gamboa
4.77 out of 5 average rating, 56 reviews

Gamboa rainforest lodging

Our restored canal zone home sits on a cul-de-sac in historic Gamboa. It is surrounded by trees and overlooks the town with Panama Canal and passing ships in the distance. An original Damon Kyllo mural adorns one large wall. You will love the balcony, high ceilings, artwork, breezes, and the cacophony of frogs, monkeys, and parrots. This is a great place for birdwatchers and a starting point for exploring the Panama Canal, Soberanía National Park, and the Chagres River.

Guest favorite
A serene swimming pool is depicted surrounded by lush palm trees, with the tranquil sea visible in the background. The water's clear blue tiles reflect the sky and nearby greenery, while the gentle curvature of the pool edge invites relaxation.
Villa in Portobelo
4.97 out of 5 average rating, 77 reviews

Entire Villa with pool in front of beach!

Beautiful spacious 4 bedroom villa right in front of the sea. Enjoy the swimming pool with your family, then take a dip into the sea only steps away. Very pet friendly! Take a boat trip for the day with a local certified tour guide from portobelo town. Every room has full AC, including the living room - but please be conscious of the environment when using ACs. Excellent WiFi ! Open Kitchen, with breakfast included. We can also arrange for lunch - fresh lobster!

Top guest favorite
An aerial view of a resort along a coastline shows a series of buildings surrounded by lush greenery and sandy beaches. Clear turquoise waters gently lap against the shore, and pathways meander throughout the area, connecting various facilities and natural landscapes.
Condo in Maria Chiquita
4.98 out of 5 average rating, 103 reviews

Apartment in Playa Escondida.

Recap Playa Escondida is a small 'paradise' an hour from the city. It is located in the Republic of Panama, in the coastal area of Costa Arriba in the Caribbean Sea. You can spend the day preparing your barbecue in a waterfront Bohío or if you prefer, savor the delights of the restaurants. And if you decide on physical activities, you will find soccer fields, volleyball, fishing or paddling, and it has water games for children that they will undoubtedly enjoy.

Top guest favorite
Apartment in Panamá
4.96 out of 5 average rating, 27 reviews

Gorgeous Flat in the best location in Casco Viejo

This cute and stylish studio is perfectly located in the heart of Casco Viejo, Panama City’s most charming historic district. Recently renovated, it combines modern comfort with classic charm inside a beautiful colonial building—just steps from top restaurants, bars, monuments, and attractions. The space includes a comfortable sofa bed, making it ideal for a couple or a small family looking to enjoy the vibrant atmosphere of Casco right outside their door.

Guest favorite
The entrance to the building is framed by manicured trees and architectural elements. Large glass doors lead into the space, reflecting warm lighting from chandeliers overhead. A pathway lined with tiles guides the way, creating a welcoming approach.
Condo in Panamá
4.97 out of 5 average rating, 38 reviews

Modern and luxurious apartment in Cinta Costera

Experience the luxurious PH Yoo overlooking the city in this elegant apartment with a king-size bed and floor-to-ceiling windows. Enjoy world-class amenities: swimming pool, gym, squash court, spa, and more. Prime location near tourist areas, restaurants, bars, and shopping malls. Inside the building there are dining options with exclusive discounts and free valet parking. Modern, spacious and sophisticated space for an unforgettable getaway.

Top guest favorite
A private pool area is framed by lush tropical plants and trees, with lounge chairs situated nearby. The pool’s clear blue water reflects the surrounding greenery and the structure in the background, which includes a covered patio for relaxation.
Home in Las Colinas de Caceres de Arraijan
4.98 out of 5 average rating, 222 reviews

Tropical Haven with Yoga Platform

Tropical "open-concept" Airbnb, with a private pool and yoga/meditation platform, located in a typical village, 20 minutes outside the hustle of Panama City, Panama - Central America. This modern contemporary tropical home is located in the hills of Caceres on a 5 acre finca full of tropical trees, birds, and a manicured grounds. Outdoor gas and charcoal barbecue off of back patio with vertical herb garden for perfect relaxation retreat.

Guest favorite
Apartment in Panamá
4.99 out of 5 average rating, 136 reviews

Full apartment in Panama

This charming apartment is located in one of the best neighborhoods in Panama, San Francisco, a downtown location where you will find ample cuisine, entertainment venues, close to bus stations, and the city's most important shopping mall, Multiplaza. This central and quiet apartment is an opportunity you won't want to miss. It offers the perfect combination of comfort, beauty, and a convenient location.

Guest favorite
A bright, open living area features large sliding glass doors that provide a view of the water. A light-colored sectional sofa is positioned next to a modern coffee table, and a sleek television is mounted on the wall. Natural light fills the room, creating a relaxed atmosphere.
Condo in Maria Chiquita
5 out of 5 average rating, 45 reviews

Playa Escondida, Ocean View

Excellent two-bedroom luxury apartment with beautiful ocean views in Playa Escondida. Equipped with everything you need. Access to the exclusive white sand spas, several pools, playground, water park, gym, restaurants, barbecue, bohios, spa, paddle court, soccer field, night entertainment, and various other amenities. It is a unique, beautiful and exclusive place to spend with family and friends.

Popular amenities for Barro Colorado Island vacation rentals