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Vacation rentals in Barro Colorado Island

Find and book unique accommodations on Airbnb

Top-rated vacation rentals in Barro Colorado Island

Guests agree: these stays are highly rated for location, cleanliness, and more.

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Guest favorite
The image captures a serene beach scene featuring a sandy shoreline and clear turquoise waters. Thatched-roof gazebos are visible near the water, alongside a wooden pier extending into the sea. Various boats are moored in the distance, surrounded by tropical greenery.
Vacation home in Maria Chiquita
4.86 out of 5 average rating, 101 reviews

Dreamy, Modern Caribbean Home at Playa Escondida

Have fun with the whole family at Casa Capri, a dreamy place which is a perfect fit both for adults & kids. The apartment is at Playa Escondida, a stylish resort with white sand beaches and crystal clear ocean water, several amenities such as a restaurant (with a broad range of great food, including fresh seafood and sushi!), pools to chill or swim, plus fantastic and diverse children playgrounds. Whether you'd like to have a resting vacation or a fun getaway, Casa Capri got you covered. Enjoy!

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Guest favorite
An open-concept loft is showcased with a high, sloped ceiling and large windows that invite natural light. Comfortable seating is arranged around a glass table, while a dining area and a cozy sleeping space can be seen in the background. Nature views are visible through the windows.
Home in Santa Rita Arriba
4.95 out of 5 average rating, 19 reviews

The Bird's Nest in the Clouds

Escape to the Clouds: A Nature Lover’s Retreat. Welcome to The Bird's Nest, a serene loft in Santa Rita Arriba, Colón, 50 minutes from the city. Perched in the mountains, this open-concept space offers breathtaking views, fresh breezes, and the sounds of nature - rain and birds. Sleep with doors open, no AC. Perfect for nature lovers, not for those needing silence or climate control. Pool with breathtaking view, wifi and modern comforts included. PLEASE READ ENTIRE DESCRIPTION BEFORE BOOKING.

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Top guest favorite
A charming apartment building is nestled among lush greenery and tall trees. The exterior features a welcoming porch with railings and is surrounded by tropical plants, creating a serene environment. Natural sunlight filters through the leaves, highlighting the vibrant foliage.
Guesthouse in Gamboa
4.94 out of 5 average rating, 87 reviews

Gamboa Toucan Apartment casa # 126

Welcome to Gamboa! Only 35 minutes from downtown Panama, Gamboa. Situated in Soberanía National Park and on the shores of the Panama Canal, is a Mecca for Birdwatchers and Nature enthusiasts! Watch the wildlife right from the backyard of your fully equipped apartment. Feel the magic songs of thousands of birds welcoming the twilight of sunrise and dusk in this century old community. Easily explore wildlife on trials through the surrounding old growth jungle and by boat on the Panama Canal.

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Top guest favorite
Apartment in San Felipe
4.98 out of 5 average rating, 130 reviews

The View of Casco: Designer Loft with best Balcony

Sip your morning coffee or evening wine on the balcony, taking in a stunning, panoramic view of the city skyline! ​Experience the absolute best of Casco Viejo from this elegant, fully remodeled 1-bedroom loft. Nestled inside a beautifully restored 1850 colonial building—featuring historic, original calicanto walls—this stylish space puts the entire city at your doorstep. ​You are just steps away from world-class dining, vibrant cafes, museums, and Casco's legendary nightlife

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Superhost
A stone guesthouse with a traditional thatched roof is surrounded by lush greenery. Banana plants and palm trees are visible in the foreground, while a small outdoor seating area with chairs is featured in front of the house, providing a welcoming ambiance.
Guesthouse in Santa Rosa
5.0 out of 5 average rating, 12 reviews

Chagres River Lodge

You stay in our guest house on the River Chagres, in the village Santa Rosa. it is a stone house with a beautiful Panama rancho over it, so the house stays nice and cool. In our garden you have large trees with many birds such as parrots. We have a sloth in the tree. In the morning you can hear the monkeys on the other side and you can explore the area with the canoe. Or take a dip in the river to cool off. A boat to Gamboa or the Panama Canal is a 20 minute boat ride.

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Superhost
A tranquil dipping pool is framed by lush greenery, featuring white loungers and a large umbrella for shade. The pool area exudes a serene vibe with vibrant bougainvillea in the background, enhancing the inviting outdoor space.
Home in Taboga Island
4.94 out of 5 average rating, 223 reviews

Casa Rosie - Dream Home on Tabogá Island

Casa Rosie is a gorgeous villa on Taboga island with an intimate vibe and spectacular views of the ocean. The perfect place for couples, small groups, and families to unwind and make magical memories! . With great wifi, fully equipped kitchen, 3 inviting bedrooms, and a spacious yet personal feel… Casa Rosie is your home away from home. Included in every stay is free pick up and drop off to the ferry terminal - please let us know the details of your arrival.

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Top guest favorite
The private outdoor pool is set against a backdrop of lush greenery and the home's elegant architecture. Comfortable seating arrangements are positioned nearby on the pool deck, inviting relaxation. Large windows reflect natural light, enhancing the spaciousness of the surrounding area.
Villa in San Francisco
4.97 out of 5 average rating, 119 reviews

Beautiful House in Panama w/ King Beds + Pool

Beautiful home in Punta Paitilla featuring 6 bedrooms, 5.5 bathrooms, and 8 beds, comfortably accommodating up to 16 guests. Enjoy a private pool, in-home gym, and spacious, modern living areas designed for families, groups, or business travelers. The layout offers both privacy and comfort across two levels. Located in one of Panama City’s most exclusive neighborhoods, just minutes from restaurants, shopping centers, supermarkets, and the Cinta Costera.

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Superhost
The villa's modern exterior is illuminated at night, showcasing a sleek facade with clean lines. Lush landscaping with palm trees frames the entrance. A vehicle is parked in front, highlighting the spacious driveway. The large front steps lead to the welcoming double doors.
Home in Veracruz
4.94 out of 5 average rating, 32 reviews

Luxury beachfront villa!

Discover luxury in our new oceanfront villa in Veracruz Chumical, just 30 minutes from Panama City. With 5 bedrooms, 6 bathrooms, 5 king beds and 2 double cabins, it is ideal for families and friends. Relax in the infinity pool with spectacular views or enjoy the equipped kitchen, spacious living room and barbecue area. Take in the illuminated ships on the rooftop and enjoy a unique experience. Book now and enjoy being the first in our beautiful Villa!

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Top guest favorite
A private pool area is framed by lush tropical plants and trees, with lounge chairs situated nearby. The pool’s clear blue water reflects the surrounding greenery and the structure in the background, which includes a covered patio for relaxation.
Home in Distrito Arraijan
4.98 out of 5 average rating, 234 reviews

Tropical Haven with Pickleball/Yoga Platform

Tropical "open-concept" Airbnb, with a private pool and yoga/meditation platform, located in a typical village, 20 minutes outside the hustle of Panama City, Panama - Central America. This modern contemporary tropical home is located in the hills of Caceres on a 5 acre finca full of tropical trees, birds, and a manicured grounds. Outdoor gas and charcoal barbecue off of back patio with vertical herb garden for perfect relaxation retreat.

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Top guest favorite
Apartment in Maria Chiquita
5.0 out of 5 average rating, 16 reviews

Luxury Beachfront Escape | Playa Escondida Resort

Luxury beachfront apartment literally on the sand in Playa Escondida. Designer furniture, premium mattresses, private bathroom in every bedroom, guest half bath, split A/Cs + central A/C with aromatherapy. Professional kitchen, filtered hot/cold water, dishwasher, full laundry, luxury BBQ & oceanview balcony. 5 min walk to beach club, restaurants, gym, spa & convenience store. Family friendly. No dogs allowed. 1.5 hrs from Panama City.

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Guest favorite
Home in Gamboa
4.86 out of 5 average rating, 111 reviews

BirdHouse — Gamboa, Panama Canal Rainforest

BirdHouse: Let's inhabit the space. Designed for people who want to experience the tropics, not shut them out. Open the screens, feel the breeze, listen to the rain, cool off in the pool, and wake to birds and howler monkeys. Located in historic Gamboa, BirdHouse is a place to slow down and experience one of the world’s richest tropical forests from the comfort of a thoughtfully designed home.

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Guest favorite
A bright living area features large glass doors that provide a panoramic view of the beach and ocean. A spacious sectional sofa is positioned near natural light, complemented by a wooden dining table. Elegant decor elements include woven light fixtures and fresh greenery.
Condo in Maria Chiquita
4.99 out of 5 average rating, 91 reviews

Playa Escondida with the Best Direct Ocean View

Wake up to the Caribbean blue from your private balcony, coffee in hand. Enjoy direct beach access, breathtaking ocean views, and a peaceful escape just one hour from the city. 4 rooms & 4 bathrooms ⭐ Premium - Fully stocked kitchen - In-unit washer and dryer - Nespresso/Drip/French Press coffee machine - High-speed WiFi - Ergonomic desk and office chair - Baby crib - High chair (baby)

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Popular amenities for Barro Colorado Island vacation rentals