House vacation rentals in Tower Grove South

A spacious living area features a plush blue sofa and a light gray armchair, complemented by a coffee table. A dining nook with red chairs is visible through large windows, while a modern kitchen is seen in the background, highlighting bright cabinetry and a clean layout.

4.91 out of 5 average rating, 208 reviews

Comfy Private Family Home next to Community Garden

Sit on white Eames chairs and a built-in bench in an inviting dining nook where antique and modern accents mingle. Pull stools up to an island in a kitchen overlooking a grassy, fenced backyard. Child-friendly touches include toys and books for use. Truly in the heart of it all, we are only steps away from the Morganford Business district with local eateries, pubs, coffee/tea shops, and grocer. We are next door to the Community garden space, of which there is a free Little Library out front. We are several blocks from Tower Grove Park, the neighborhood's 289 acre gem that holds countless events throughout the year. Additionally, we are centrally located to all of St. Louis' main attractions as listed below: -1.4 mi (6 min) from the famous Missouri Botanical Gardens -2.5 mi to Historic Soulard and Anheuser-Busch Brewery -4.0 mi from St. Louis Zoo and St. Louis Science Center, (both are Free!) -5.0 mi from the Jewel Box in Forest Park -5.0 mi (10 min) from Busch Stadium -5.5 mi from America's Center Convention Center and The Gateway Arch -18 mi (25 min) from STL Airport For families traveling with kids we offer extras that you are welcome to use: Pack N Play with mattress + sheet, baby gates, booster seat, high chair, night lights, sound machines, rainbow light machine, baby bouncer, toys/books. Guests will have access to the entire house and fenced backyard We love sharing our slice of the city with guests! We give you your space. We live nearby and are available to help you with recommendations and are only a phone call away in the case any issues come up. This home is in the bustling Tower Grove South neighborhood, in the heart of the Morganford Business District. Eateries, coffee shops, and groceries are just steps away. The 289-acre park nearby offers stunning views, playgrounds, and lots of events! Although St. Louis metro area is generally easier to enjoy by car, staying here puts you steps away from the bus stop at Morganford and Connecticut, which offers easy transfer to the Metro Rail at Grand Center, which connects with Amtrak and St. Louis Lambert Airport. Ridesharing (Uber, Lyft) and taxi services are also available. There is street parking in front of the house, as well as a dedicated parking pad for 2 cars in the back (alley access) if you are bringing or renting a car. *** IMPORTANT, PLEASE READ *** There are approximately 6 steps up from the sidewalk to the main floor. Watch out for the step halfway between the sidewalk and the main steps. For those who have decreased mobility, the master suite is located on the main floor. There is dual-zone central heating and air conditioning, with Nest thermostats downstairs (hallway to master) and upstairs (just outside bedroom door to the left at top of stairs).

A well-lit guest room features tall vaulted ceilings with exposed wooden beams and skylights. A cozy bed is adorned with patterned bedding, while decorative plants are placed around the space. Large windows allow natural light to fill the room, complemented by soft curtains.

4.91 out of 5 average rating, 422 reviews

Sunny South City Guest House

Newly-rehabbed & cozy guest house. Everything you need is located here in the historic Bevo Mill neighborhood. In the heart of south St. Louis city, you’re steps away from local businesses, including the picturesque, historical Das Bevo. Step into a vintage-styled oasis, featuring large windows with plenty of natural light, tall vaulted ceilings, comfy queen bed, unique fridge, breakfast bar, sizable bathroom with a large walk-in shower. Hang outside at the picnic table under cute string lights.

Home in Shaw Historic District

The modern living room features a comfortable white leather couch, a coffee table with magazines, and a cozy armchair. Natural light floods in through large windows, illuminating the space with warm tones. The open kitchen can be seen in the background, equipped with stainless steel appliances.

4.91 out of 5 average rating, 127 reviews

Magnolia House | Botanical Garden | Parkside Shaw

Welcome to Magnolia House, a modern, renovated 1st floor flat in the historic Shaw Garden District. Designed for short and long-term stays, the spacious living room, fully equipped kitchen, dedicated workspace, backyard w/grill and picnic table, and two king-size hotel-quality bedrooms make it the perfect home away from home. Conveniently located on Tower Grove Park and the Botanical Gardens w/easy access to highways, hospitals, and STL's best neighborhoods. Message for discounted 30+ day stays!

4.99 out of 5 average rating, 129 reviews

The living room features a brown leather sofa with decorative yellow pillows and a coffee table with a rustic wooden top and slender metal legs. A cozy armchair is positioned nearby, accompanied by a soft throw blanket. Natural light illuminates the space through sheer curtains.

Home in Lindenwood Park

Near Forest Park, The Hill, WashU-Private Backyard

Backyard is private, large, fully fenced. Sitting area w/ solo stove & Adirondack chairs. Cleaned & maintained by host. Inside 1 bedroom you will find comfy king bed, queen sofa in living room. Modern amenities, fully stocked kitchen, & coffee bar. First floor laundry. Centrally-located, newly updated near The Hill & Forest Park. 1 min. from highway & no more than 10 mins from most everything STL-restaurants, downtown, hospitals, zoo, science center, coffee shops, stadiums & more! Dogs allowed!

Colorful flowers and greenery line the flower bed in front of the cottage. Several flowering plants are visible, accompanied by neatly trimmed boxwood shrubs. The pathway is paved, leading up to the home's entrance, with a mix of sunlight and shade enhancing the natural landscape.

4.96 out of 5 average rating, 122 reviews

New: Cozy Cottage Near The Hill

Enjoy full access to this adorable cottage, also known as “The Blue Abode.” It is a small house with a large fenced-in backyard, and 2 off-street parking spaces nestled along the 15-acre Sublette Park in Southwest Gardens, within walking distance to restaurants and shops on The Hill. Freshly updated with modern renovations and stylish furnishings, this cozy pet-friendly home ($100 pet fee) is perfect for a solo traveler and spacious enough for up to 4 guests. Body wash and shampoo dispenser.

4.99 out of 5 average rating, 112 reviews

Kalisto House: 420 Retreat w/Concierge & Hottub

Take it easy at this tranquil BNB retreat in historic Tower Grove Heights, St. Louis. Nestled in a preserved 120-year-old flat, Kalisto House offers an immersive experience for the canna-curious to the Cannaseur. With cannabis-inspired art, a serene meditation room, and concierge service, this sanctuary invites you to explore, unwind, and connect. From personalized pairings to guided rituals, every detail is curated for an unforgettable, elevated escape. Ask about premium & bespoke experiences.

Superhost

The dining area features a wooden table surrounded by six chairs, illuminated by a chandelier above. A colorful piece of wall art and a vase with fresh flowers adorn the table. Large windows provide natural light, enhancing the warm atmosphere.

4.87 out of 5 average rating, 196 reviews

* Historic/Renovated * Hot Tub * Fireplace*Yard

• HotTub! • 7 Minute drive to downtown STL • 5 Minute walk to Tower Grove Park • Onsite, parking for 1 vehicle with free street parking • Fireplace! • Bike Score 91 ('Biker's Paradise') • Onsite washer + dryer Our spacious family home is ready to share with STL visitors looking for a cozy and spacious place to stay. With a comfy living room with a fireplace, you might just want to move right in. You will have full access to the property with easy access to all the fun St. Louis has to offer!

A rustic brick wall serves as a backdrop for a decorative mantel adorned with candles and memorabilia. A small, lit Christmas tree enhances the cozy atmosphere, while a television sits atop a wooden stand, completing the living space's vintage charm.

4.92 out of 5 average rating, 484 reviews

The 1904 WORLD’S FAIR RETREAT

The World's Fair Retreat will not only give you one of the most unique and enjoyable stays in the Midwest, but it will also take you back in time to 1904 when St. Louis was not only a major industrial empire, but a crown jewel of the ENTIRE WORLD - thanks to the 1904 World's Fair held in the Forest Park of St. Louis. This retreat is situated in the cozy & hip Tower Grove East neighborhood, where true STL city locals live, shop, eat, drink, and be merry! A one-of-a-kind St. Louis experience!

A wooden bookshelf is filled with an assortment of dog-themed figurines and decorations, arranged alongside a framed portrait of a dog. Pink wallpaper with a dog print serves as the backdrop, while small lace doilies add a decorative touch. A collection of DVDs is neatly displayed below.

4.96 out of 5 average rating, 139 reviews

Granny's DOG House - KING BED - One of a Kind!

ONE OF A KIND HOUSE - Welcome to Granny's Dog House! This cozy 2BR/1BA retreat, designed for dog lovers, offers a king bed in BR1, two twin beds in BR2, and charming dog-themed décor. Enjoy our fully-equipped kitchen, pristine bathroom, & fenced backyard for your furry friends. Unwind in a lovingly curated home, surrounded by dog photos, sculptures, and the warmth of canine camaraderie. Experience love, laughter, and wagging tails at our house for you and your four-legged family members!

4.99 out of 5 average rating, 196 reviews

Sparkling Vintage Charmer, King Bed, Quiet Comfort

The Fairview is a vintage modern 2BR home in desirable North Hampton (south StL city). We've taken special care to offer a unique, memorable experience while providing the convenient, clean comfort you expect in an overnight stay. You'll have easy access to two major highways which means most StL attractions will be minutes away. (The drive to Barnes Hospital is less than 10 min.) The Fairview is nearby restaurants, coffee shops and shopping––it's the perfect place to live like a local!

The house showcases classic craftsman architecture with a decorative front porch and intricate wooden details. A well-maintained lawn surrounds the entrance, and neighboring buildings provide a glimpse of the charming neighborhood. Windows allow natural light to illuminate the facade.

4.99 out of 5 average rating, 245 reviews

Spacious Family & Friends House Across From Tower Grove Park

Climb the front steps of a remarkably preserved craftsman period house with its exterior character intact. Inside is a modern space that's been remodeled top to bottom to a high level of quality and style, including a chef's kitchen and formal dining area. The house is the perfect place for large groups and families wanting plenty of space to spread out, relax and spend time together. Very kid friendly with porta cribs, highchairs, strollers and a baby monitor available for your use.

The spacious living area features a dining table with six chairs and pendant lighting above. A comfortable seating arrangement surrounds a cozy fireplace, with a mounted TV on the adjacent wall. Hardwood floors add warmth to this inviting space.