Boutique hotel vacation rentals in St. Louis County

Find and book unique boutique hotel rentals on Airbnb

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Popular amenities for St. Louis County boutique hotel rentals

Family-friendly boutique hotels rentals

Guest favorite
The room features a spacious bed adorned with a patterned blanket, complemented by a bright artwork above. A warm lamp provides soft light, and a ceiling fan is visible. The room has light blue walls and two windows dressed with light curtains, enhancing the natural light.
Hotel room in St. Louis
4.86 out of 5 average rating, 766 reviews

The Maple Room Queen Bed at BnB in CWE!

CodyRating, 5 stars3 weeks ago
I’ve stayed here twice now. Both stays went perfectly well. Even though this is a shard bathroom/kitchen, you will hardly even notice. The real + is the amount of amenities that the bathroom has and that the kitchen has comparable to a hotel room is unbelievable! You have to see the shower it’s huge! He also responds immediately to any questions or requests that I’ve had. Every time I stay in St. Louis, I will always go back to Brandon’s.
Guest favorite
A spacious room features a King-sized bed adorned with a patterned throw, accompanied by a pullout sleeper sofa. Two pieces of wall art add a touch of color, while a large television and a dark wood cabinet provide functionality. Soft lighting enhances the inviting ambience.
Hotel room in St. Louis
4.9 out of 5 average rating, 901 reviews

King Redwood Bedroom at BnB in CWE!

Alexandra NoelRating, 5 stars2 weeks ago
Brandon and Sam’s Place was perfect for us it was close to the city. It was easy to take Ubers. we loved walking down the street to Whole Foods. There was also a beautiful Catholic cathedral with mosaics that we went to go explore around the corner Their place was so homey it felt like we were staying with family!! It was very peaceful and quiet. The bed was so comfortable and cozy! I honestly can’t wait to come back. Brandon and Sam are very generous. We enjoyed a bagel one morning!
Guest favorite
A bright bedroom is adorned with a light blue wall, creating a serene atmosphere. The spacious bed is covered with a decorative blanket, flanked by crisp white linens. A bedside table and a dresser provide practical storage, while a large window allows natural light to fill the room.
Hotel room in St. Louis
4.87 out of 5 average rating, 720 reviews

Blue Spruce Room Queen Bed at BnB in CWE!

TannerRating, 5 stars1 month ago
Great stay, second time in this location, will be interested in coming back
Guest favorite
A welcoming guest room features a queen-sized bed with a brass frame and patterned bedding. A wooden side table is positioned beside the bed. A small work desk and chair are situated near the window, while soft lighting casts a warm glow in the space.
Hotel room in St. Louis
4.87 out of 5 average rating, 634 reviews

Evergreen Room Queen Bed at BnB in CWE

JocelynRating, 5 stars1 month ago
We really enjoyed this Airbnb! They had such clear instructions both in the bathroom and kitchen - I wish more Airbnb’s were that thorough.

Boutique hotels rentals with a patio

Guest favorite
An open living area with high, wooden ceilings features a spacious kitchen adorned with dark granite countertops. Intricate stained glass windows fill the space with natural light, while a grand staircase and wooden dining area are visible, creating a welcoming atmosphere.
Hotel room in St. Louis
4.97 out of 5 average rating, 35 reviews

Luxury Retreat, Hot Tub,En-Suite Bath, Location+

TimRating, 5 stars1 month ago
We really loved our stay and we will definitely be back. One of my favorite Air BNB stays to date.
A clean bathroom is featured, containing a shower-tub combination. A gray shower curtain hangs to one side, with a white towel neatly placed on the edge. The doorway leads into the guest room, visible in the background.
Hotel room in Saint Charles
4.68 out of 5 average rating, 233 reviews

1st Capitol Mansion Boutique Hotel - Suite 301

AaronRating, 5 stars1 week ago
We stayed in a small unit - It is just a bedroom and a bathroom - but it was all we needed. I liked it because we couldn't have made use of anything else so the price was excellent AND we there is comfy little coffee shop across the street and I was able to walk into the historic area and around by the river. If I was looking for something super fancy - this wouldn't be it. It was clean, matched expectations, instructions were clear. We would stay again!
Top guest favorite
The exterior of a restored Gothic-style church features a red brick facade and intricate architectural details. Two prominent stained glass windows are showcased, while a tower rises elegantly, capped with a rooftop area. Lush greenery and flowering plants enhance the entrance, contributing to the inviting atmosphere.
Hotel room in St. Louis
5 out of 5 average rating, 13 reviews

Luxury Retreat, Hot Tub,En-Suite Bath, Location+

MeganRating, 5 stars2 months ago
We cannot say enough good things about this place. The hot tub had an incredible view, and the room itself was so comfortable and luxurious. The whole place was very clean and well-maintained. We are already planning our next trip to the Gothic Heights Inn!
Top guest favorite
The exterior of the historic Gothic-style church showcases a unique blend of brick and stone architecture, featuring decorative arched windows and a prominent turret. Lush greenery surrounds the property, while an outdoor patio area with stone seating adds to the inviting atmosphere.
Hotel room in St. Louis
5 out of 5 average rating, 26 reviews

Luxury Retreat, Hot Tub,En-Suite Bath, Location+

StephanieRating, 5 stars1 month ago
Absolutely wonderful stay! Had a kitchen for use! Also was very thoughtful and had random necessities for use if you forgot yours during travel! Very beautiful and would definitely stay again!!!
Top guest favorite
The spacious bedroom features a king-size bed covered with a soft white bedspread. A vibrant mural adorns one wall, while exposed brick adds a historical touch. Hardwood flooring contrasts with the patterned black and white area rug. A large window allows natural light to fill the room.
Hotel room in Saint Charles
5 out of 5 average rating, 16 reviews

#3 Betty Bloomer Le Velo Inn

RachelRating, 5 stars4 days ago
I can’t say enough about Susanne ! She is truly the BEST! Very very sweet , accommodating, understanding and very caring! I rented the boutique for my son and his wife and she went above and beyond my expectations to make it the perfect stay as possible. I am truly thankful for her and God has really blessed her. I haven’t experienced so much kindness ever since I’ve been booking Airbnb’s. I am definitely going to book a stay at one of her boutiques with me and my husband. I am just so overjoyed of how accommodating and sweet she truly is.
Superhost
A spacious loft area is characterized by green walls and exposed brick accents. A comfortable green sofa is paired with a wooden coffee table, while a king-sized bed is positioned nearby. Natural light enters through large windows, framed by soft curtains.
Hotel room in Saint Charles
5 out of 5 average rating, 3 reviews

#6 The Green Tyke Le Velo Inn

SierraRating, 5 stars2 weeks ago
The best Airbnb i’ve ever stayed at. The aesthetics are amazing. I took pictures for inspiration -from the glasses to drink out of to the wall decorations - to the couch. I felt right at home & I have such a peaceful experience when I stayed here. I can’t wait to come back.

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