
Boutique hotel vacation rentals in St. Louis County
Find and book unique boutique hotel rentals on Airbnb
Top-rated boutique hotel rentals in St. Louis County
Guests agree: these boutique hotel rentals are highly rated for location, cleanliness, and more.
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Guest favorite

Hotel room in St. Louis
4.86 out of 5 average rating, 766 reviewsThe Maple Room Queen Bed at BnB in CWE!
CodyRating, 5 stars3 weeks ago
I’ve stayed here twice now. Both stays went perfectly well. Even though this is a shard bathroom/kitchen, you will hardly even notice. The real + is the amount of amenities that the bathroom has and that the kitchen has comparable to a hotel room is unbelievable! You have to see the shower it’s huge! He also responds immediately to any questions or requests that I’ve had. Every time I stay in St. Louis, I will always go back to Brandon’s.
Guest favorite

Hotel room in St. Louis
4.9 out of 5 average rating, 901 reviewsKing Redwood Bedroom at BnB in CWE!
Alexandra NoelRating, 5 stars2 weeks ago
Brandon and Sam’s Place was perfect for us it was close to the city. It was easy to take Ubers. we loved walking down the street to Whole Foods. There was also a beautiful Catholic cathedral with mosaics that we went to go explore around the corner Their place was so homey it felt like we were staying with family!! It was very peaceful and quiet. The bed was so comfortable and cozy! I honestly can’t wait to come back. Brandon and Sam are very generous. We enjoyed a bagel one morning!
Guest favorite

Hotel room in St. Louis
4.87 out of 5 average rating, 720 reviewsBlue Spruce Room Queen Bed at BnB in CWE!
TannerRating, 5 stars1 month ago
Great stay, second time in this location, will be interested in coming back
Guest favorite

Hotel room in St. Louis
4.87 out of 5 average rating, 634 reviewsEvergreen Room Queen Bed at BnB in CWE
JocelynRating, 5 stars1 month ago
We really enjoyed this Airbnb! They had such clear instructions both in the bathroom and kitchen - I wish more Airbnb’s were that thorough.
Boutique hotels rentals with a patio
Guest favorite

Hotel room in St. Louis
4.97 out of 5 average rating, 35 reviewsLuxury Retreat, Hot Tub,En-Suite Bath, Location+
TimRating, 5 stars1 month ago
We really loved our stay and we will definitely be back. One of my favorite Air BNB stays to date.

Hotel room in Saint Charles
4.68 out of 5 average rating, 233 reviews1st Capitol Mansion Boutique Hotel - Suite 301
AaronRating, 5 stars1 week ago
We stayed in a small unit - It is just a bedroom and a bathroom - but it was all we needed. I liked it because we couldn't have made use of anything else so the price was excellent AND we there is comfy little coffee shop across the street and I was able to walk into the historic area and around by the river. If I was looking for something super fancy - this wouldn't be it. It was clean, matched expectations, instructions were clear. We would stay again!
Top guest favorite

Hotel room in St. Louis
5 out of 5 average rating, 13 reviewsLuxury Retreat, Hot Tub,En-Suite Bath, Location+
MeganRating, 5 stars2 months ago
We cannot say enough good things about this place. The hot tub had an incredible view, and the room itself was so comfortable and luxurious. The whole place was very clean and well-maintained. We are already planning our next trip to the Gothic Heights Inn!
Top guest favorite

Hotel room in St. Louis
5 out of 5 average rating, 26 reviewsLuxury Retreat, Hot Tub,En-Suite Bath, Location+
StephanieRating, 5 stars1 month ago
Absolutely wonderful stay! Had a kitchen for use! Also was very thoughtful and had random necessities for use if you forgot yours during travel! Very beautiful and would definitely stay again!!!
Top guest favorite

Hotel room in Saint Charles
5 out of 5 average rating, 16 reviews#3 Betty Bloomer Le Velo Inn
RachelRating, 5 stars4 days ago
I can’t say enough about Susanne ! She is truly the BEST! Very very sweet , accommodating, understanding and very caring! I rented the boutique for my son and his wife and she went above and beyond my expectations to make it the perfect stay as possible. I am truly thankful for her and God has really blessed her. I haven’t experienced so much kindness ever since I’ve been booking Airbnb’s. I am definitely going to book a stay at one of her boutiques with me and my husband. I am just so overjoyed of how accommodating and sweet she truly is.
Superhost

Hotel room in Saint Charles
5 out of 5 average rating, 3 reviews#6 The Green Tyke Le Velo Inn
SierraRating, 5 stars2 weeks ago
The best Airbnb i’ve ever stayed at. The aesthetics are amazing. I took pictures for inspiration -from the glasses to drink out of to the wall decorations - to the couch. I felt right at home & I have such a peaceful experience when I stayed here. I can’t wait to come back.
Destinations to explore
- Rentals with a patio St. Louis County
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- Rentals with a fire pit St. Louis County
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- Busch Stadium
- Six Flags St. Louis
- Central West End
- Saint Louis Zoo
- Enterprise Center
- Gateway Arch National Park
- Missouri Botanical Garden
- City Museum
- Cuivre River State Park
- St. Louis Aquarium at Union Station
- Pere Marquette State Park
- The Winery at Aerie's Resort
- Meramec State Park
- Saint Louis Science Center
- Cathedral Basilica of Saint Louis
- Castlewood State Park
- Grafton Winery the Vineyards
- Adventure Valley Zipline Tours and Paintball Park
- Raging Rivers WaterPark
- St. Louis Country Club
- Missouri History Museum
- Norwood Hills Country Club
- Hidden Valley Ski Resort
- Boone Valley Golf Club