Vacation rentals in Sisters Creek

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Top-rated vacation rentals in Sisters Creek

Guests agree: these stays are highly rated for location, cleanliness, and more.

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Superhost
Guest suite in Jacksonville Beach
4.89 out of 5 average rating, 306 reviews

Suite Dreams@Waterfront Oasis@JaxBeach/Mayo/TPC

This 💦waterfront 🏖Studio Suite is 1 of a kind! French Doors that lead into✨Suite Dreams has been described by many as🤩 💫Mesmerizing & Relaxing. ✨ Mayo is 3 miles away! 🏖is 6min & ⛳️Jax Golf a 2min drive, this is your perfect Oasis✨ A private walkway leads to a beautifully 🕯lit custom built deck.✨ Until you experience it, can you truly appreciate the tranquility of this ✨Stunning Oasis Suite Dreams is designed to make you feel relaxed as you will find spa-like items & may never want to leave!

Top guest favorite
Home in Jacksonville
5 out of 5 average rating, 31 reviews

Guests Rave “Cleanest Airbnb”| Near Mayo & Beaches

• Central location- Mayo Clinic, Beach, Dining, Parks • Game Room with Ping Pong & Foosball • Kid-friendly + travel crib + highchair + utensils • Fast Wi-Fi + Dedicated Workspace • Books, Board Games & Video Games • Fast Wi-Fi + dedicated workspace • Fully stocked kitchen • Luxe bathrooms + sound system • Safe, quiet neighborhood • Washer + dryer • Three coffee makers—Nespresso, Keurig, and drip— fully stocked with coffee, cream, and sweeteners. • 1 mile from Ed Austin Park- Playgrounds & trails

Guest favorite
Cottage in Neptune Beach
4.92 out of 5 average rating, 368 reviews

Beach Getaway with Outdoor Space. Steps to Sand

30secs walk to the beach! This modern beach house is exactly the getaway you need! Easy 15 mins walk to both JAX Beach downtown and Beaches Town Center restaurants, but quiet neighborhood & access to less crowded part of the beaches 1 block away. Completely renovated with luxurious, modern and chic decor. Private entrance to UPSTAIRS of a beach duplex with private balcony and yard w/outdoor shower. No shared space. 2 dedicated parking spaces. Dogs ok, NO cats. No longer offer fire pit for safety

Top guest favorite
A cozy living space showcases a dark leather sofa and two patterned armchairs, providing a comfortable seating area. A decorative ottoman sits in front of the sofa, with a small table positioned nearby. Natural light filters through the windows, illuminating the warm wood flooring.
Guesthouse in Jacksonville
4.9 out of 5 average rating, 125 reviews

Location! Pelican Point riverfront with oceanview

LOCATION,Private! Island Life Mouth of St.John's River.Deep water, great fishing. Atlantic Ocean! In Preserves surrounded by beaches, nature, creeks, inlets, rivers. On A1A Buccaneer Trail scenic hwy. Pelicans, dolphins, manatees, huge ships, yachts, shrimpboats, etc. seen daily Located between Jax & Amelia Island/Fernandina.20 mins airport/Zoo. Slow down in our peaceful, private, rustic, not fancy but clean home. Dock fishing. Limited to 2 adult guest. No Pets/children/guest of guest!!

Top guest favorite
The image captures a serene view of the St. Johns River at sunset. Soft hues of orange and blue blend in the sky, reflecting onto the water's surface. A rocky shoreline frames the foreground, emphasizing the natural beauty of the river and the evening sky.
Tiny home in Jacksonville
4.93 out of 5 average rating, 144 reviews

Little Pink Cottage By the Sea

Little Pink Cottage welcomes you to Fanning Island overlooking the St Johns River from your private deck~Cozy studio, brand new, comfy Queen bed, table for 2 or enjoy morning coffee or evening drink on the deck and enjoy the amazing, ever changing views of our wonderful river. Dolphins, pelicans, egrets can often be found playing, frolicking and fishing around the dock. Fishing poles are available for you & bait shops are near by. Come rest, relax & rejuvenate in our little paradise by the sea.

Top guest favorite
A spacious studio is featured with warm orange walls and natural light from multiple windows. A dark bed is positioned against a textured headboard. A cozy loveseat and table are situated nearby, complemented by a workspace with a desk. A bathroom area is visible in the background.
Guest suite in Ponte Vedra Beach
4.98 out of 5 average rating, 380 reviews

Palm Valley Escape with Private Studio Entry

Fabulous Private Studio in a Natures Wonderland. Lots of privacy in the "jungle room" Private driveway . Walk to rear of house and up the steps to the entry door on right. You'll be given the code prior to entry- Light and bright private studio is warm and welcoming. Make use of the Coffee Bar with lots of amenities, WIFI and YoutubeTV. You control the AC Separate air unit in the studio. Come and go as you want to privately without interruption. 10 min drive(30 min bike ride) to the ocean.

Top guest favorite
A neatly arranged living space features a spacious bed with a patterned black and white comforter. A wall-mounted TV and a small desk with a chair are visible. Light flows in through the window, adorned with dark curtains, while a potted plant decorates the coffee table.
Tiny home in Jacksonville
4.95 out of 5 average rating, 274 reviews

Sugarberry Tiny Home on 2.5 Acres with Pond/Patio

Relax at this quaint and laid-back getaway located close to restaurants, airport, cruise terminal and major highways. The property is near nature preserves and state parks that are ideal for hiking , fishing and boating or just relax in any of our many beautiful beaches and enjoy all the fine dining. For entertainment and event venues , Riverside/Downtown is under 30 minutes away. A great place to relax and rest after a day of activities or on your way to your final travel destination.

Top guest favorite
Guesthouse in Jacksonville
4.95 out of 5 average rating, 600 reviews

Jax Backyard Bungalow

Rent this dog friendly guest house in our quiet well-groomed backyard. Studio comes with queen-size bed, couch, closet, mini fridge, Keurig, microwave, table & chairs. Enjoy DirecTV & dedicated WiFi router. Savor a peaceful cup of coffee or evening cocktail on the attached wood deck. Well behaved dogs are encouraged to run free in the fully fenced in yard. Our black lab would love the company! Get to TIAA Bank Field in less than 5 mins or the beach in about 25 mins. Must be 25 to book

Guest favorite
A comfortable sleeping area features a spacious bed adorned with decorative pillows and a light quilt. A flat-screen TV is mounted on the wall opposite the bed. Soft lighting highlights the relaxed atmosphere, while a doorway leads to a bathroom in the background.
Apartment in Jacksonville
4.93 out of 5 average rating, 350 reviews

White Rock Studio

Parking for 1 vehicle only Studio apt. attached to our house but privately separated. Centrally located in Jacksonville, only a ten minutes to the beaches, 12 minutes to mayo clinic. Unit has all you need for a week long stay or just one night. Full Kitchen and laundry. Decorative Lighted patio available for all guests. Comfortable Queen sized bed easily sleeps 2, crib available on request for infants younger than 2. Hosts are friendly and answer communications immediately. Thank you.

Guest favorite
The treehouse is illuminated at night, showcasing its elevated wooden structure supported by stilts. Surrounding palm trees are visible, and soft lighting highlights the entrance and balcony area, creating a welcoming outdoor space.
Treehouse in Jacksonville
4.85 out of 5 average rating, 175 reviews

Treehouse Hideaway in the Timucuan Preserve

Our treehouse is located on 1 of the many islands located within the Timucuan Ecological Preserve and has been branded as the North Florida Keys(it is accessible by car). The Hideaway was just recently remodeled with modern taste and simple design to ensure that our guests feel comfortable in every aspect of their stay. The space has 1 bedroom, kitchen, bathroom and living room. The house also sits on a large lot so our guests can bring their boats or pwc’s to enjoy the local waters.

Top guest favorite
A peaceful riverfront scene is depicted, featuring the sun rising above calm waters. Silhouetted trees frame the view, while colorful clouds reflect on the water. Adjoining the shore, a dock extends into the water, complemented by wooden chairs placed on the grassy lawn.
Apartment in Jacksonville
5 out of 5 average rating, 106 reviews

Riverfront Relaxation | Fish, Boat, Unwind

Welcome to Sunrise Suite — a private 2,000 sq ft retreat with breathtaking sunrise views and no shared indoor spaces. Located above the garage, this spacious guest suite features one bedroom, one bathroom, and three comfortable beds within an airy open layout. Large windows fill the space with natural light, creating the perfect place to relax and recharge. Nestled in nature yet minutes from Jacksonville International Airport and major highways for easy access.

Top guest favorite
A modern kitchen is highlighted by sleek white cabinetry and stainless steel appliances. Pendant lights hang above the countertop, providing illumination. Behind the kitchen area, a cozy living space with large windows allows natural light to fill the room, showcasing plants and decorative elements.
Home in Jacksonville
4.98 out of 5 average rating, 188 reviews

Luxe Home &Dreamy Backyard 20min from Mayo Clinic

Have fun with the whole family at this stylish newly renovated home. Everything is modern & BRAND NEW! Enjoy a nice cozy evening in the backyard next to the fire. We have a king size bed in the master including a private FULL bathroom with a stand-up glass shower. The 2nd bedroom has a queen size bed next to the 2nd bedroom that has a garden tub. The living room couch pull outs & makes for queen bed. Each room has a smart tv with all your favorite shows.

Popular amenities for Sisters Creek vacation rentals

  1. Airbnb
  2. United States
  3. Florida
  4. Duval County
  5. Jacksonville
  6. Sisters Creek