House vacation rentals in Simpsonville

Find and book unique houses on Airbnb

Top-rated house rentals in Simpsonville

Guests agree: these houses are highly rated for location, cleanliness, and more.

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Guest favorite
A serene bedroom features a spacious bed dressed in white linens, complemented by decorative pillows. Two bedside tables with lamps frame the bed, while a television is mounted on the wall across from it. Natural light filters through sheer curtains, enhancing the calming atmosphere.
Home in Simpsonville
4.93 out of 5 average rating, 111 reviews

Hidden Gem - Private Home - 3 BDRM In 5 Forks

Freshly renovated 3 bedroom home in highly sought after 5 Forks area. Beautiful space for family or multiple couples to enjoy inside or outside with open living and big back deck. Stay in and cook in our gorgeous kitchen that any woman would want to bring home with them OR go out and have many options at your fingertips on Woodruff Road. Come back to our comfortable queen sized beds in each bedroom and enjoy the peace and quiet of our home and 1.5 acre lot. Pet fee is required for furry friend

Top guest favorite
A screened porch is highlighted, featuring comfortable wooden seating with light cushions and a matching table. Natural light is allowed through large windows and a skylight, providing a view of the surrounding greenery. A small potted plant decorates the table, enhancing the relaxing atmosphere.
Home in Greenville
4.96 out of 5 average rating, 154 reviews

The Greenville Nest - Retreat & Relaxation Home

This beautifully one-level home offers 3 queen beds and 2 baths, accommodating up to 6 guests. Centrally located in a peaceful neighborhood. 8-minute drive to GSP airport, 15-minute drive to downtown Greenville, minutes from I-85/385, and minutes from Woodruff and Pelham Rd. You'll appreciate the easy access to food delivery and restaurants. Enjoy a stylish Experience for entertaining, working, and relaxing with high-speed Wi-Fi. Quiet and safe with an enjoyable private screened porch and Grill.

Guest favorite
A bright living room features a comfortable gray sofa, patterned accent chairs, and a glass coffee table. Large windows allow natural light to fill the space. In the outdoor area, a playground with a slide and climbing structure is visible within a fenced yard, perfect for children.
Home in Simpsonville
4.89 out of 5 average rating, 122 reviews

Spacious 4 BR Escape w/ Fenced Yard Near Downtown

Welcome to your stylish retreat, conveniently located just 3 minutes from the shopping & dining in charming Downtown Simpsonville & convenient to everything that Greenville has to offer. With 4 bedrooms, 2 full baths & a fenced in yard, this house has everything you need for your stay. Located in a safe & quiet neighborhood just 20 minutes from downtown Greenville & 5 minutes to all of your daily needs. <B>Traveling with a large group? Ask about our other 4BR house across the street!<B>

Top guest favorite
The living area features a light-colored sofa with decorative pillows, a matching loveseat, and a wooden coffee table. A large flat-screen TV is mounted on the wall, while a stone accent wall adds texture. Natural light enters through double doors leading to an outdoor space.
Home in Greenville
4.99 out of 5 average rating, 175 reviews

Peaceful Retreat - Perfect Location

SUPER CLEAN HOUSE!!! This house promises comfort, relaxation and close-by shopping and awesome restaurants!! Check out beautiful Greenville!! vacations, tournaments, holidays -- IN PERFECT LOCATION!! **Perfectly located near I-85 and I-385 with easy access to downtown (8.5 miles), GSP Airport (8.5 miles), **Close to best shopping in town. **Quiet neighborhood!! **Small park in neighborhood. **Many wonderful restaurants. **Close to ICAR, GE, BMW. **Trampoline Park close by.

Guest favorite
A living area features contrasting armchairs in orange and a gray sofa, complemented by a coffee table with a decorative tray. A wooden mantel with a mounted television overlooks an electric fireplace, while natural light filters through two windows draped with light-colored curtains.
Home in Fountain Inn
4.92 out of 5 average rating, 100 reviews

Carolina's Olde Mill, family friendly

Your family will be close to everything when you stay at this centrally-located house. New 2023 build in a quiet neighborhood, 1 mile from downtown Fountain Inn and 18 miles to Greenville. Just 2 blocks from Interstate 385. Olde Mill is located only a few miles to Walmart, grocery store, restaurant's and shopping. Spacious place to unwind after a day of exploring or stay in and play cards/board games provided. Hot out... let kiddos run thru the sprinkler! Enjoy grilling on covered deck.

Guest favorite
The exterior of a light yellow cottage is visible, framed by lush greenery. A covered entrance leads to the front door, flanked by two windows. Soft sunlight casts gentle shadows, enhancing the natural surroundings. The peaceful setting is complemented by well-maintained shrubs and trees.
Home in Simpsonville
4.91 out of 5 average rating, 102 reviews

Simple Circle Cottage - Quiet. Quaint. Close.

Just 3 blocks from the heart of downtown Simpsonville - come enjoy all that our charming town has to offer without giving up the peace & quiet of a country retreat! Walk to a variety of small retail shoppes and restaurants including Southern-style BBQ, Mexican, Thai, Pizza, authentic crêpes, gourmet coffee, ice cream and more! The police & fire stations are within 1 block, as well as City Park. 3 min to Heritage Park Amphitheater <15 min to downtown Greenville 20 min to GSP AIrport

Top guest favorite
The image features four panels: a ping pong table in a well-lit space, a decorated bedroom with a king bed and ambient lighting, a cozy children's room with a twin over full bunk bed and cheerful decor, and a bedroom showcasing a playful wall with vibrant colors and an umbrella design.
Home in Greenville
4.95 out of 5 average rating, 126 reviews

Family home w/ PingPong & Playset-Central location

This is a very family friendly home with a playset, toys, and ping pong. It’s centrally located with all the shopping & restaurants you need just a couple miles away, and downtown Greenville is a 14 minute drive! The Millennium Campus and St. Francis Millennium Hospital are just a couple minutes away. The house is in a very safe neighborhood, with a nice walking trail nearby. It is a very comfortable and clean home that features all new mattresses, beds, washer, dryer, & much more!

Guest favorite
A contemporary living area features a comfortable gray sofa with accent pillows, positioned beside a coffee table. A flat-screen TV is mounted on a shiplap wall above an electric fireplace. Natural light floods the space through window coverings, illuminating the stylish decor.
Home in Simpsonville
4.97 out of 5 average rating, 146 reviews

Modern Farmhouse in Downtown Simpsonville, SC

Newly renovated two-bedroom home located in downtown Simpsonville, within easy walking distance of an excellent variety of restaurants, shops and places of interest. A spacious private balcony, leading off from the main bedroom suite overlooks a peaceful backyard... a great place to relax outdoors! The kitchen is fully equipped for preparing great meals. Our home is thoroughly and professionally cleaned & sanitized. ***Please note there is a train that runs midday and late at night.

Top guest favorite
Home in Greenville
4.97 out of 5 average rating, 124 reviews

4b Home w/ Private Porch Near Furman- New Kitchen!

This 4 bedroom, 2.5 bath home sleeps 8 guests. Located centrally- less than ten minutes from downtown Greenville, Cherrydale, Travelers Rest, Paris Mountain, Furman, North Greenville, and Timmons Arena. Newly remodeled kitchen! Food delivery & rideshare is readily available in this area. This newly renovated home is spacious, with a beautiful backyard patio in a fenced yard. Equipped with good wifi, washer and dryer, fully stocked kitchen, luxury linens, TV's, full sized fridge.

Top guest favorite
A split-level home is set amidst a well-maintained lawn, featuring a welcoming entrance with a front door framed by windows. Lush greenery and trees surround the property, and a pathway leads to the entrance, providing easy access.
Home in Greenville
4.99 out of 5 average rating, 192 reviews

2 Living Spaces -2800 ft.²- Sleeps 10

This spacious split-level house is in a quiet neighborhood and has plenty of room for 10 guests. Enjoy a king bed in the master bedroom, and 3 additional bedrooms, each featuring a queen bed. 2 single trundle beds are also available for the little ones. This home has space to gather everyone together or spread out and have some quiet time. Some fun features of this home are an outdoor fire pit, pool table, fenced backyard, deck with grill, and 3 smart TVs. 4 bedroom 3 bath home.

Top guest favorite
Home in Simpsonville
5 out of 5 average rating, 20 reviews

Comfy, Dog-Friendly, Nice Community w a Pool

Need good rest on a comfy mattress with soft cotton sheets? Need to be less than 5 minutes away from a grocery store, urgent care and some shops and restaurants? Fenced-in yard?! Then book our place! :) Relax and recharge in our recently refreshed and stylish house with a fenced in yard and patio. Enjoy your nights at a fire-pit making s’mores and grilling dinner on a charcoal grill. Comfortable beds with cotton linens and fluffy down comforters assure a restful sleep!

Top guest favorite
The treehouse structure features a distinctive A-frame design with large glass paneling allowing for abundant natural light. Surrounded by trees, an outdoor deck with seating complements the lush woodland setting. The rooftop deck above adds to the unique architectural appeal.
Home in Greenville
4.99 out of 5 average rating, 259 reviews

Cozy Treehouse

Situated at the back of a wooded 2 acre lot, only 10 minutes from downtown Greenville, this is a little oasis in the city! While most treehouses take you on a "roughing it" adventure, Cozy Treehouse is the glamping version of treehouses, boasting 9' ceilings, 1.5 baths, 3 LED TV's and many outdoor living options. If you are looking for a unique getaway just minutes from one of the top growing cities in the south, Cozy Treehouse is the perfect destination for you.

Popular amenities for Simpsonville house rentals

When is the best time to visit Simpsonville?

MonthJanFebMarAprMayJunJulAugSepOctNovDec
Avg. priceG$26,308 GYDG$27,143 GYDG$27,143 GYDG$25,264 GYDG$26,517 GYDG$26,517 GYDG$24,846 GYDG$26,725 GYDG$25,890 GYDG$26,725 GYDG$23,593 GYDG$26,308 GYD
Avg. temp6°C8°C12°C16°C20°C25°C27°C26°C23°C17°C11°C7°C

Quick stats about house rentals in Simpsonville

  • Total vacation rentals

    Explore 70 vacation rentals in Simpsonville

  • Nightly prices starting at

    Simpsonville vacation rentals start at G$6,264 GYD per night before taxes and fees

  • Verified guest reviews

    Over 2,510 verified reviews to help you choose

  • Family-friendly vacation rentals

    40 properties offer extra space & kid-friendly amenities

  • Pet-friendly vacation rentals

    Find 20 rentals that welcome pets

  • Rentals with dedicated workspaces

    40 properties have a dedicated workspace

  • Wi-Fi availability

    70 of Simpsonville vacation rentals include wi-fi access

  • Popular amenities for guests

    Guests love Kitchen, Wifi, and Pool across Simpsonville rentals

  • 4.8 Average rating

    Simpsonville stays are highly rated by guests—averaging 4.8 out of 5!