House vacation rentals in Simpsonville

The Greenville Nest - Retreat & Relaxation Home

This beautifully one-level home offers 3 queen beds and 2 baths, accommodating up to 6 guests. Centrally located in a peaceful neighborhood. 8-minute drive to GSP airport, 15-minute drive to downtown Greenville, minutes from I-85/385, and minutes from Woodruff and Pelham Rd. You'll appreciate the easy access to food delivery and restaurants. Enjoy a stylish Experience for entertaining, working, and relaxing with high-speed Wi-Fi. Quiet and safe with an enjoyable private screened porch and Grill.

Fenced in Yard, 2 Queen Beds, Downtown!

Hard to beat this amazing value! Nestled on a quiet street 5 minutes from downtown, this 2bed/1bath property is perfect for your visit to Greenville. Each bedroom has a queen bed and plenty of closet space with hangers. Out back, there's a spacious deck to relax on, and the property has a fenced in yard which would be ideal for your curious furry friend. This property is minutes from hospitals & interstate 85. Ideal for work travelers, or simply curious visitors. There's a driveway for parking.

Spectacular home 1 mile from Main St Greenville!

Enjoy your stay in this charming up to date house 1 mile from Main St Greenville! Take a walk through the Historic Pinckney district on your way to Greenville’s museums, restaurants, theaters, and stunning Reedy River Falls Park. Easy access to the Swamp Rabbit biking and walking trail, and just 4 blocks from the upcoming Unity Park. House is located on quiet residential street with private driveway. Relax on rocking chairs on front porch or around a portable fire pit in large backyard.

Pet-Friendly 2BR • Fenced Yard Near Downtown GVL

Located in Greenville’s Historic Dunean District, this cozy 2BR home is less than 10 minutes to Downtown Greenville, Unity Park, Falls Park, and the Swamp Rabbit Trail. Enjoy a pet-friendly stay with a fully fenced backyard, enclosed sunroom with hammock, garden views, and high-speed fiber WiFi. This is an allergy-friendly, fragrance-free home using only non-toxic cleaning and laundry products—no scented candles or air fresheners. Nestled in a quiet, safe neighborhood close to restaurants.

2BR Greer Condo: Pet-Friendly, King Beds, Fire Pit

Discover our stunning 2BR/2BA single-level home, just 1 mile from Downtown Greer & a 30-min drive to Downtown Greenville. This beautifully designed retreat accommodates 4 guests, offering a King bed in each bedroom for a restful stay. Unwind in style with a shared community fire pit, perfect for cozy evenings. Experience the charm of local attractions, dining, & shopping while enjoying a comfortable and stylish home away from home. Book now for an unforgettable stay in this idyllic haven.

Near Downtown! 1 Bed Minutes to Everything!

Cozy 1 Bedroom duplex within walking distance to restaurants and shopping. One mile to Bon Secours Wellness Arena and 3 minute drive to downtown Greenville. 1.5 Miles to Bob Jones University. Perfect for a business traveler or couple for a getaway trip to our great city! Pet friendly, Free parking, king sized bed, extra comfy linens, clean towels, and a comfortable atmosphere to relax during your stay. Space comes with VERY FAST and FREE WIFI, SMART TV and a fully stocked kitchen.

Modern Farmhouse in Downtown Simpsonville, SC

Newly renovated two-bedroom home located in downtown Simpsonville, within easy walking distance of an excellent variety of restaurants, shops and places of interest. A spacious private balcony, leading off from the main bedroom suite overlooks a peaceful backyard... a great place to relax outdoors! The kitchen is fully equipped for preparing great meals. Our home is thoroughly and professionally cleaned & sanitized. ***Please note there is a train that runs midday and late at night.

Simpsonville Southern Comfort

Welcome to Simpsonville Southern Comfort! Our home offers a comfortable, completely remodeled space with all of the amenities of home to make your stay enjoyable. This home is in a GREAT location just a 5-minute drive from the conveniences of the Five Forks area, and a short 7-minute drive to the enjoyment of The Square in Downtown Simpsonville. Our home is also a quick 20-minute drive from GSP International Airport, and 20 minutes from Downtown Greenville. Enjoy your stay!

Greenville Prime Location-Steps from Swamp Rabbit

You'll love the abundant natural light in this peaceful one bedroom retreat. We are located in the Pettigru Historic District and are just a 5 minute walk from Bon Secours Wellness Arena and a 15 minute walk to Main Street. This is an upstairs unit (1 of 3 total units located within the triplex) and has a private, exterior entrance. There's a kitchen with all the utensils, pots, bowls, plates, cups, etc. that you could need for your stay as well as a stocked Nespresso machine!

Greenville Modern Retreat - 8 minutes to Downtown

Decorated in a mid century modern theme, this home is perfect for couples and business travelers looking for a peaceful, modern aesthetic filled with natural light. This home is located in San Souci just 2.5 mi (8min drive) to downtown Greenville. It is also conveniently located 1/2 mi to the Swamp rabbit trail and the Swamp Rabbit Grocery. Please see “Where you’ll be” section for further description of location and the neighborhood. We're excited to have you join us!

Family & Pet Friendly Home - Sleeps 8

Our home is absolutely perfect for entertaining, work and relaxation. Enjoy fast wifi and free coffee. Connect over a meal at our spacious dining table. Families will love the large, fenced-in backyard, toys and board games in our huge rec room, complete with ping pong table! Quiet and easy connections to Greenville & Simpsonville. Only 5 mins from Discovery Island Waterpark. Community park and playground accessible with lots of space to roam with family or pets.

Cozy Treehouse

Situated at the back of a wooded 2 acre lot, only 10 minutes from downtown Greenville, this is a little oasis in the city! While most treehouses take you on a "roughing it" adventure, Cozy Treehouse is the glamping version of treehouses, boasting 9' ceilings, 1.5 baths, 3 LED TV's and many outdoor living options. If you are looking for a unique getaway just minutes from one of the top growing cities in the south, Cozy Treehouse is the perfect destination for you.