House vacation rentals in Simpsonville

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Top-rated house rentals in Simpsonville

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Top guest favorite
A welcoming entryway features a brick patio surrounded by trees, providing a natural setting. Two chairs and a small table sit on one side, with a cozy seating area visible. The home showcases large windows that allow for ample natural light.
Home in Greenville
4.98 out of 5 average rating, 210 reviews

A Tranquil Place (near downtown Greenville)

A Tranquil Space is conveniently located close to Downtown Greenville. The large suite includes the bedroom, living area, kitchenette (fridge/freezer/convection oven), bathroom, and study/eating area. It is newly renovated area on the end of my home with a private entrance. The space is welcoming and inviting...a perfect space to get away from the hustle. Although minutes from Downtown, the suite feels like you're in the mountains with a private back yard and many trees. Enjoy your stay!

Top guest favorite
A serene bedroom is highlighted by a four-poster bed adorned with decorative pillows and a soft blanket draped at the foot. Natural light filters through the sheer curtains on the left, while a gold-toned coffee table sits in front of the bed, providing a modern touch.
Home in West End
4.91 out of 5 average rating, 150 reviews

Last Minute Best City Nest w Parking-Walk Downtown

Experience the fun of downtown GVL! Walk the illuminated Main St. Trolley,bike, walk to eateries-breweries-shops-Falls/bridge-trails-theaters/venues & fun. Singles, couples-co-workers-friends-art/music lovers +. Entire 2nd floor. Newly renovated spacious historic loft- 9' ceiling-wood floors-lg glass shower. Relax on private balcony,cook in large kitchen, fast wifi/desk & record player.1300 sq ft.3 beds & luxe bath. SMART TV.Less busy area 1/2 block fr Main St.Sleeps 4.AGES 12+ per safety info

Superhost
A cozy living area features a leather couch adorned with pink cushions, positioned near a decorative glass coffee table. Sunlight filters through the windows, illuminating a flat-screen television above a white mantel. A small side table and a bookshelf add functional charm to the space.
Home in Greenville
4.82 out of 5 average rating, 172 reviews

Fenced in Yard, 2 Queen Beds, Downtown!

Hard to beat this amazing value! Nestled on a quiet street 5 minutes from downtown, this 2bed/1bath property is perfect for your visit to Greenville. Each bedroom has a queen bed and plenty of closet space with hangers. Out back, there's a spacious deck to relax on, and the property has a fenced in yard which would be ideal for your curious furry friend. This property is minutes from hospitals & interstate 85. Ideal for work travelers, or simply curious visitors. There's a driveway for parking.

Top guest favorite
An open-concept living area features a modern kitchen with stainless steel appliances and a spacious island, complemented by a dining table. A cozy living room is equipped with a soft sectional sofa facing a mounted television and warm electric fireplace. Natural light enhances the inviting atmosphere.
Home in Greenville
4.98 out of 5 average rating, 132 reviews

Greenville GEM Luxurious Retreat in Prime Location

Beautifully renovated 3 beds, 2 baths haven! This gem is a tranquil & stylish retreat, blending modern & cozy charm. Spacious bedrooms, each with plush bedding and storage. Two Bathrooms with soaking tub and a spacious walk-in shower. Cozy living room with a fireplace, TV, and comfy seating.  Fully equipped kitchen, Wi-Fi, Private deck and gazebo, fenced yard. Close to the city's best attractions, dining, and entertainment options. This is the perfect home base for your Greenville adventures.

Guest favorite
A bright living room features a comfortable gray sofa, patterned accent chairs, and a glass coffee table. Large windows allow natural light to fill the space. In the outdoor area, a playground with a slide and climbing structure is visible within a fenced yard, perfect for children.
Home in Simpsonville
4.9 out of 5 average rating, 114 reviews

Spacious 4 BR Escape w/ Fenced Yard Near Downtown

Welcome to your stylish retreat, conveniently located just 3 minutes from the shopping & dining in charming Downtown Simpsonville & convenient to everything that Greenville has to offer. With 4 bedrooms, 2 full baths & a fenced in yard, this house has everything you need for your stay. Located in a safe & quiet neighborhood just 20 minutes from downtown Greenville & 5 minutes to all of your daily needs. <B>Traveling with a large group? Ask about our other 4BR house across the street!<B>

Guest favorite
The living room features a green sectional sofa arranged around a round wooden coffee table. A textured area rug anchors the seating area. A desk with a lamp and chair is positioned against the wall, complemented by decorative plants and wall art.
Home in Greenville
4.93 out of 5 average rating, 108 reviews

Pet-Friendly 2BR • Fenced Yard Near Downtown GVL

Located in Greenville’s Historic Dunean District, this cozy 2BR home is less than 10 minutes to Downtown Greenville, Unity Park, Falls Park, and the Swamp Rabbit Trail. Enjoy a pet-friendly stay with a fully fenced backyard, enclosed sunroom with hammock, garden views, and high-speed fiber WiFi. This is an allergy-friendly, fragrance-free home using only non-toxic cleaning and laundry products—no scented candles or air fresheners. Nestled in a quiet, safe neighborhood close to restaurants.

Guest favorite
An open living space features a vibrant accent wall adorned with botanical wallpaper. A custom emerald green sofa and accent chair provide seating around a rustic wooden coffee table. The kitchen and dining area are visible, showcasing an inviting atmosphere with modern appliances and ample seating.
Home in Pleasant Valley
4.96 out of 5 average rating, 152 reviews

3BR Retreat Near Augusta Rd & Downtown w/ Patio

Tucked away just off Augusta Rd near Downtown Greenville, Flora Sanctuary is your custom oasis to relax and recharge. At our home, you are less than 2 miles from I-85 for easy access to all the upstate has to offer. Our home is thoughtfully designed to provide an upscale experience for our guests both inside and out. We are: ~Less than a mile from Greenville Country Club Chanticleer Golf Course ~Less than 5 miles from N Main St and Falls Park ~5 miles from Bon Secours Wellness Arena

Guest favorite
A contemporary living area features a comfortable gray sofa with accent pillows, positioned beside a coffee table. A flat-screen TV is mounted on a shiplap wall above an electric fireplace. Natural light floods the space through window coverings, illuminating the stylish decor.
Home in Simpsonville
4.96 out of 5 average rating, 133 reviews

Modern Farmhouse in Downtown Simpsonville, SC

Newly renovated two-bedroom home located in downtown Simpsonville, within easy walking distance of an excellent variety of restaurants, shops and places of interest. A spacious private balcony, leading off from the main bedroom suite overlooks a peaceful backyard... a great place to relax outdoors! The kitchen is fully equipped for preparing great meals. Our home is thoroughly and professionally cleaned & sanitized. ***Please note there is a train that runs midday and late at night.

Top guest favorite
A bright living room features two leather sofas positioned around a cozy area rug. Large windows provide ample natural light, with a mounted TV above a wooden mantel. Decorative wall frames add character to the space, complemented by a soft throw draped over one of the sofas.
Home in Simpsonville
4.96 out of 5 average rating, 156 reviews

Simpsonville Southern Comfort

Welcome to Simpsonville Southern Comfort! Our home offers a comfortable, completely remodeled space with all of the amenities of home to make your stay enjoyable. This home is in a GREAT location just a 5-minute drive from the conveniences of the Five Forks area, and a short 7-minute drive to the enjoyment of The Square in Downtown Simpsonville. Our home is also a quick 20-minute drive from GSP International Airport, and 20 minutes from Downtown Greenville. Enjoy your stay!

Guest favorite
A living area features large windows that allow ample natural light, complemented by soft white drapes. A comfortable sofa and two armchairs are arranged around a light area rug, with a small table nearby. A television is mounted above a modern fireplace.
Home in Greenville
4.89 out of 5 average rating, 138 reviews

Greenville Prime Location-Steps from Swamp Rabbit

You'll love the abundant natural light in this peaceful one bedroom retreat. We are located in the Pettigru Historic District and are just a 5 minute walk from Bon Secours Wellness Arena and a 15 minute walk to Main Street. This is an upstairs unit (1 of 3 total units located within the triplex) and has a private, exterior entrance. There's a kitchen with all the utensils, pots, bowls, plates, cups, etc. that you could need for your stay as well as a stocked Nespresso machine!

Top guest favorite
A charming exterior view of the home features light beige siding and a welcoming blue front door. Windows with blinds allow natural light to brighten the interior. The manicured front yard includes low shrubs, and a concrete walkway leads to the entrance.
Home in Greenville
4.94 out of 5 average rating, 125 reviews

Greenville Modern Retreat - 8 minutes to Downtown

Decorated in a mid century modern theme, this home is perfect for couples and business travelers looking for a peaceful, modern aesthetic filled with natural light. This home is located in San Souci just 2.5 mi (8min drive) to downtown Greenville. It is also conveniently located 1/2 mi to the Swamp rabbit trail and the Swamp Rabbit Grocery. Please see “Where you’ll be” section for further description of location and the neighborhood. We're excited to have you join us!

Top guest favorite
A calming bedroom features a spacious bed with crisp white linens and decorative pillows. A ceiling fan enhances airflow, while a large TV is mounted on the wall. A potted plant adds a touch of greenery, and soft light is provided by bedside lamps.
Home in Greenville
4.99 out of 5 average rating, 146 reviews

Family & Pet Friendly Home - Sleeps 8

Our home is absolutely perfect for entertaining, work and relaxation. Enjoy fast wifi and free coffee. Connect over a meal at our spacious dining table. Families will love the large, fenced-in backyard, toys and board games in our huge rec room, complete with ping pong table! Quiet and easy connections to Greenville & Simpsonville. Only 5 mins from Discovery Island Waterpark. Community park and playground accessible with lots of space to roam with family or pets.

Popular amenities for Simpsonville house rentals

When is the best time to visit Simpsonville?

MonthJanFebMarAprMayJunJulAugSepOctNovDec
Avg. priceG$26,970 GYDG$26,134 GYDG$25,507 GYDG$25,297 GYDG$26,552 GYDG$26,552 GYDG$24,879 GYDG$26,761 GYDG$25,925 GYDG$26,552 GYDG$25,297 GYDG$27,806 GYD
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Quick stats about house rentals in Simpsonville

  • Total vacation rentals

    Explore 80 vacation rentals in Simpsonville

  • Nightly prices starting at

    Simpsonville vacation rentals start at G$6,272 GYD per night before taxes and fees

  • Verified guest reviews

    Over 2,360 verified reviews to help you choose

  • Family-friendly vacation rentals

    40 properties offer extra space & kid-friendly amenities

  • Pet-friendly vacation rentals

    Find 20 rentals that welcome pets

  • Vacation rentals with a pool

    10 properties feature pools

  • Rentals with dedicated workspaces

    40 properties have a dedicated workspace

  • Wi-Fi availability

    80 of Simpsonville vacation rentals include wi-fi access

  • Popular amenities for guests

    Guests love Kitchen, Wifi, and Pool across Simpsonville rentals

  • 4.8 Average rating

    Simpsonville stays are highly rated by guests—averaging 4.8 out of 5!