
Vacation rentals in Santiago
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Top-rated vacation rentals in Santiago
Guests agree: these stays are highly rated for location, cleanliness, and more.

Santiago lake Route
Enjoy a comfortable and peaceful stay in the heart of Santiago de Veraguas. Our accommodation offers a prime location, ideal for those seeking comfort and convenience. Just a 3-minute walk from Avenida Central, you will have everything within easy reach: supermarkets, grocery stores, restaurants, etc. It's the perfect space to relax before or after a great adventure. We look forward to welcoming you and providing you with a cozy place where your stay will be truly comfortable. We look forward to seeing you!
LocationNearbySleep quality

Casa Valle de Barbarena
Excelente ubicación cerca del centro a tan solo 2 kilómetros un lugar tranquilo. Cerca del mall Casa de dos cuartos y dos camas Doble un sofá cama Espacio de Lavandería o depósito de almacenamiento Ve vecindario tranquilo Nice location near the city 2 km Away from the center of Santiago close to the mall It has 2 rooms each with a doble bed and a sofa bed in the living room Laundry room with nice space to bring in your bike or any thing that you will like to store inside the house.
FamilyLocationNearby

House minutes from Santiago, U Latina, HospChichoF.
Spacious, comfortable and fully equipped house in a strategic location in Santiago. Perfect for all types of guests: families, business travelers, students, people coming to medical appointments or those looking for a quiet and accessible space. The house is located very close to Dr. Chicho Fábrega Hospital, Clínica Norte, U.Latina, Oxford School, shops, supermarkets, pharmacy, restaurants, and minutes from downtown Santiago. A safe place for short and long stays.
LocationFamilyHospitality

San Juan Loft
San Juan Loft is a comfortable apartment located in the heart of Santiago de Veraguas, ideal for staying one or more nights. It features a bedroom with air conditioning, a private bathroom, an equipped kitchen, a living room, a dining room, Wi-Fi, and private parking. We also provide complimentary coffee, tea, sugar, and salt. In addition, we offer self-check-in. Perfect for travelers, work, or relaxation in one of the most important cities in inland Panama.
LocationAccessQuiet

Santiago city, home w/ spacious living & office
Spacious and peaceful home in a safe area of Santiago. 4 bedrooms (ideal for families and groups), bright living-dining area and large kitchen to share with family or friends, plus a private office for working comfortably. High-speed Wi-Fi, air conditioning and fans in all rooms, fully equipped kitchen, washer/dryer, and safe for valuables. Self check-in with smart lock, parking for several cars, and a coffee station with board games and karaoke.
FamilyLocationNearby

La Casita de Yary
My place is special for its comfort and location. This place is perfect to enjoy on business trips, as a group, or to relax as a family. Strategically located at the entrance to the city of Santiago, it puts you close to everything: supermarkets, restaurants, shopping malls, and more. 🏡 The space Enjoy a comfortable, modern, and welcoming environment that will make your stay an unforgettable experience. Smoking inside the property is prohibited.
LocationHospitalityComfort

Comfortable and safe apartment in downtown Santiago
Family apartment in downtown Santiago — comfortable, safe and fully equipped Enjoy a prime location in the heart of Santiago de Veraguas, a short walk from the cathedral, municipal park, and main avenue. Everything you need is within walking distance: supermarkets, pharmacies, banks, shops, restaurants and transportation. Ideal for families, professionals, business travelers, or people visiting the city for paperwork or events.
LocationFamilyAccuracy

Cozy and belle apartment
Whether you are going for a trip to the city of Santiago, Veraguas, or for work, in this beautiful apartment you will find comfort and tranquility so you can rest and disconnect from the daily grind. Its cozy spaces, carefully decorated and equipped, will make you feel at home from the moment you arrive. Located in a quiet and safe area, it is the ideal place to relax after a day of work, sightseeing or shopping in the city.
LocationAmenitiesComfort

2A Apartment
Accessible apartment in downtown Santiago, located 300 meters from the Transportation Terminal and within walking distance of supermarkets and businesses. With a good layout, fresh and bright, and with all the basic amenities. The apartments provide a harmonious balance in the middle of the characteristic comings and goings of the center, perfect for stays of families, friends, professionals, couples.
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d'rosas apartments 3PB
Discover comfort in our cozy accommodation in the heart of Santiago, Veraguas. Just a 5-minute walk from the city center, you'll enjoy a well-equipped space that includes all the necessary amenities for a relaxing stay. Ideal for exploring the local culture and resting after a day of adventures. We look forward to seeing you!
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2 bedroom house in Santiago
centric, well located, walking distance to downtown. Near the Panama Canal Museum, park Juan Demostenes Arosemana, and the Santiago Cathedral Juan Pablo Apostol. A few meters from central avenue.
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3BD, 2BTHS, furnished house
House with 3 bedrooms, 2 bathrooms, central, furnished, security booth, kitchen, automatic washing machine, A/A, Wi-Fi, cable TV, new construction in a nice residential area.
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Popular amenities for Santiago vacation rentals
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