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House vacation rentals in Sant'Antioco

Find and book unique houses on Airbnb

Quick stats about house rentals in Sant'Antioco

  • Total vacation rentals

    Explore 80 vacation rentals in Sant'Antioco

  • Nightly prices starting at

    Sant'Antioco vacation rentals start at G$10,439 GYD per night before taxes and fees

  • Verified guest reviews

    Over 1,990 verified reviews to help you choose

  • Family-friendly vacation rentals

    40 properties offer extra space & kid-friendly amenities

  • Pet-friendly vacation rentals

    Find 20 rentals that welcome pets

  • Rentals with dedicated workspaces

    30 properties have a dedicated workspace

  • Wi-Fi availability

    50 of Sant'Antioco vacation rentals include wi-fi access

  • Popular amenities for guests

    Guests love Kitchen, Wifi, and Pool across Sant'Antioco rentals

  • 4.8 Average rating

    Sant'Antioco stays are highly rated by guests—averaging 4.8 out of 5!

Top-rated house rentals in Sant'Antioco

Guests agree: these houses are highly rated for location, cleanliness, and more.

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Superhost
The exterior of the villa is shown, featuring a combination of stone and plaster walls. Wooden shutters are closed over the windows. A small paved area is visible with drainage grates, surrounded by greenery that enhances the natural setting.
Home in Maladroxia
4.9 out of 5 average rating, 21 reviews

Villa Ludi

Villa Ludi, located in Maladroxia, Blue Flag 2026, is the perfect choice for an unforgettable holiday on the island of Sant'Antioco. Just 100 meters from the sea, close to the nature trail in the protected area of Serra Is Portus, the villa offers 2 double bedrooms, a living room with a kitchenette and a double sofa bed, 2 bathrooms, a terrace with a relaxation area, an outdoor shower, air conditioning, TV, microwave, and Wi-Fi. Reserved parking space. Perfect for those looking for the sea and nature. CIN IT111071C2000R0458

LocationFamilyQuiet

Guest favorite
Home in Sant'Antioco
5.0 out of 5 average rating, 6 reviews

My second home in ReC IT111071C2000T0990

The house is accessed through a private alley from the main road. The parking lot is located both on the main street and about 15 meters in a large space. The house is located near the historic area of Sant'Antioco, a 5-minute walk from the beautiful Basilica of Sant'Antioco, where you will find essential services such as cafés, a convenience store, a produce shop, a fishmonger, and a pizzeria. In a 15-minute walk you can reach the tree-lined course, Via V. Emanuele, our village center. PETS ARE NOT ALLOWED.

LocationNearbyWalkability

Top guest favorite
The image captures an outdoor space visible through large glass doors. A barbecue area is situated in the garden, surrounded by greenery and shaded by trees, with a stone path leading towards it.
Home in Sant'Antioco
4.96 out of 5 average rating, 53 reviews

Mint and Rosemary - space 2

Bright apartment, furnished with all amenities, 15 minutes from the historic center. Consisting of an open-plan space with a fully equipped kitchen (oven, microwave, dishwasher, coffee maker, etc.); a living room with a TV and sofa. The two bedrooms – one double and one with two single beds – are equipped with spacious wardrobes. Comfortable bathroom with spacious shower. Garden with outdoor tables and barbecue. You can park on the property. Accommodation tax: each guest pays €1 per day

LocationValueLaundry

Superhost
An outdoor terrace is visible, featuring a white dining table and wooden chairs. Beyond the railing, a lush garden is seen, leading to a view of the sea. The area is surrounded by greenery and trees, suggesting a tranquil environment.
Home in Calasetta
4.76 out of 5 average rating, 37 reviews

"A Cà da Mamma" where the sea meets the soul

A house that smells of memories and slow time, a refuge that has seen seasons pass and smiles remain. Between walls that hold stories and a garden that smells of the sea, you will find bright rooms, enveloping silence and an atmosphere that only an authentic house full of soul can give. Ideal for those who want to breathe the beauty of small things and rediscover the magic of a space that feels like home. If you want to enter a place that embraces you, then my home is waiting for you.

LocationFamilyDecor

Guest favorite
An outdoor patio area features rustic stone walls and terracotta flooring. Lounge chairs and a dining table provide comfortable seating options. Lush greenery surrounds the space, with a scenic view of the sea and distant hills visible in the background under a cloudy sky.
Home in Domus de Maria
4.93 out of 5 average rating, 125 reviews

A haven of well-being with stunning ocean views

Casa Francesca sits on a gentle hill and offers a stunning view of Monte Gogoni beach and the lagoon, home to beautiful flamingos. Enjoy peace and total relaxation while the sun accompanies you from morning until evening. In just 4–5 minutes by bike, you can reach some of the most beautiful beaches in Italy, supermarkets, the Chia Laguna Hotel, and a variety of excellent restaurants. I know the area like the back of my hand and will be happy to help you discover it like a local.

LocationValueShared spaces

Guest favorite
A private pool is surrounded by neatly trimmed greenery and comfortable lounge chairs. A smooth stone patio offers ample space for relaxation, with vibrant grass and lush plants framing the pool area, creating an inviting outdoor retreat.
Home in Calasetta
4.92 out of 5 average rating, 142 reviews

Private pool Villa close to the beach

Brand-new two-level house with a huge garden (3,000 m² -32292ft² ), a private swimming pool, and just a 7-minute walk from Spiaggia Grande Beach. Set in the countryside and surrounded by unspoiled nature, it offers peace and privacy while staying close to the sea. Every year we focus on improving our guests’ comfort. For 2026, we completely renovated the kitchen and added a dishwasher and a large fridge, plus an automatic gate at the entrance for easier access.

LocationValueCheckout

Top guest favorite
Home in Calasetta
5.0 out of 5 average rating, 8 reviews

Villa Mameli – Just Steps from the Sea

Villa Mameli is a spacious holiday home in the charming seaside village of Calasetta, just a few steps from the sea. It accommodates up to 6 guests and features 3 air-conditioned bedrooms, 2 bathrooms, a large air-conditioned living room, a fully equipped kitchen and 4 balconies. Calasetta marina is only about 100 metres away, while the beautiful beaches of Sottotorre, Le Saline and Spiaggia Grande are all within easy reach.

FamilyLocationNearby

Top guest favorite
Home in Sant'Antioco
4.99 out of 5 average rating, 101 reviews

old and modern with design

Every detail of the house has been carefully considered and researched over time so that you can enjoy total relaxation. Complete with every accessory. The staircase is modern, so you have to be careful with children. We don't want to block it with "not suitable for children" because we love our little guests. The house has two outdoor areas, one of which allows you to organize relaxing outdoor dinners.

LocationFamilyAccuracy

Top guest favorite
A rectangular swimming pool is surrounded by a sunbathing area featuring several loungers. The clear water reflects the blue sky and nearby greenery, while the stone-paved patio provides a spacious environment for relaxation.
Home in Portoscuso
4.98 out of 5 average rating, 125 reviews

The Oasis of Relaxation

Cozy cottage immersed in the Mediterranean scrub with swimming pool, with a cool covered veranda, barbecue area, indoor and outdoor bathroom, double bedroom, both air-conditioned, living room including eat-in kitchen and air conditioning. 2 km from the sea and the town of Portoscuso and about 50 minutes from Elmas Airport.

LocationFamilyKitchen

Superhost
A bright living area features a spacious white sofa facing large windows showcasing a serene view of the sea and distant mountains. A dining table is set with tableware, complementing the light-colored decor. Air conditioning is visible on the wall, adding comfort.
Home in Sant'Antioco
4.85 out of 5 average rating, 92 reviews

Beachfront house

Elegant and comfortable apartment, beach front, suitable for a family or two couples. Wide habitable entrance, living room and kitchen from which to admire a wonderful view. Two bedrooms, a bathroom, a large entrance. Air-conditioned, equipped, and furnished with all comforts. Seaview, fantastic sunrise in the lagoon

FamilyValueBreakfast

Superhost
An outdoor dining area is shaded by a large umbrella, featuring a round table surrounded by four chairs. The ground is covered with colorful pavers, and greenery is provided by two trees and hedges that enhance the tranquil setting.
Home in Calasetta
4.91 out of 5 average rating, 58 reviews

Casa Simona

In the countryside of Calasetta in the locality of Cussorgia, a quiet and relaxing place 5 minutes from the center with the possibility of grilling and eating outdoors. Due to space issues, we do not accept campers, vans, and caravans. i.u.n. code S0682 separate cleaning with payment at the property

FamilyValueHospitality

Guest favorite
A panoramic view showcases the sun setting over the ocean, with its reflection glistening on the water. The scene includes rooftops of nearby white buildings and vibrant bougainvillea, enhancing the serene coastal ambiance. A bell tower can be seen in the foreground, adding architectural interest.
Home in Calasetta
4.94 out of 5 average rating, 70 reviews

OCEAN ALL AROUND

COZY, BRIGHT & OCEAN VIEW apartment, 150 meters from the shore but still in the center of the village. Enjoy the silence and be overwhelmed by the astonishing ocean view while seating on the roof top.

FamilyLocationAccuracy

Popular amenities for Sant'Antioco house rentals

When is the best time to visit Sant'Antioco?

MonthJanFebMarAprMayJunJulAugSepOctNovDec
Avg. priceG$17,537 GYDG$17,119 GYDG$16,911 GYDG$17,746 GYDG$18,163 GYDG$18,998 GYDG$20,669 GYDG$24,218 GYDG$19,416 GYDG$16,493 GYDG$16,702 GYDG$16,911 GYD
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