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Vacation rentals in Santa Cruz Tlaxcala

Find and book unique accommodations on Airbnb

Top-rated vacation rentals in Santa Cruz Tlaxcala

Guests agree: these stays are highly rated for location, cleanliness, and more.

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Guest favorite
Home in Santa Ursula Zimatepec
4.92 out of 5 average rating, 26 reviews

Casa Lozada – Spacious and beautiful home in Apizaco

Enjoy a comfortable, spacious and cozy home in Santa Ursula that will make you feel at home. It has 3 bedrooms, 2.5 bathrooms, equipped kitchen, terrace and garage for 2 cars. Strategic location: 10 minutes from the high-performance sports center, 10 minutes from downtown Apizaco, 20 minutes from Tlaxcala capital, 30 minutes from Huamantla and 25 minutes from the industrial corridor With easy access to transportation, supermarkets and schools. Ideal for relaxing and sharing unforgettable moments with family or friends

Guest favorite
The exterior entrance features a pathway bordered by greenery, leading to a modern façade with large windows. Plants are positioned for visual interest beside the pathway, while soft evening light enhances the welcoming appearance of the entrance.
Home in Apizaco
4.87 out of 5 average rating, 71 reviews

Complete House with 2 Bedrooms, Garden and Barbecue

Enjoy a comfortable and pleasant stay in this house with functional design and good taste. Perfect for families, couples or travelers, our house has everything you need to feel at home; comfortable rooms and hot water 24/7. Whether you are coming for work, tourism or visiting, you will find comfort and tranquility. 3 minutes from Chedraui, FEMSA, UATX, 7 minutes from the Apizaco Center, 8 from the Regional Hospital, 12 minutes from Ciudad Judicial, 20 from CIX I, and 30 minutes from La Malinche.

Guest favorite
A spacious two-story house features a warm exterior and large glass doors that connect the indoor and outdoor areas. In the foreground, a patio set with six chairs surrounds a glass table, situated on a green lawn that extends to the house.
Home in Santa María Atlihuetzia
4.88 out of 5 average rating, 24 reviews

Beautiful house with a large garden

Less than two hours from Mexico City, spacious and cozy house very well lit with large garden, ideal for resting in a peaceful place, meeting and living with family or friends, appreciate the majesty of the Malinche, have breakfast or roast a meat outdoors, even play volleyball or basketball, or relax in the jacuzzi. Strategically located 20 minutes from downtown Tlaxcala and less than an hour from tourist attractions such as El Santuario de las Luciérnagas and Val'Quirico.

Guest favorite
Loft in San Benito Xaltocan
4.89 out of 5 average rating, 46 reviews

Midnight Oasis II

Bienvenido al Oasis Natural, donde la naturaleza y el confort se fusionan para ofrecerte una experiencia única de relajación. Hemos cuidado cada detalle de nuestra habitación para brindarte una estancia agradable. Si buscas un espacio relajante en donde además puedas trabajar este es el lugar ideal. En cuanto a la ubicación, tenemos a unos pasos tiendas de conveniencia, restaurantes, bares nocturnos y farmacias, todo para que no te falte nada durante tu estancia.

Guest favorite
Home in Ocotlán
4.95 out of 5 average rating, 20 reviews

House with garden near downtown Tlaxcala.

Comfortable and quiet stay with a large garden. Just 10 minutes from downtown Tlaxcala. The space: • Entire private house • Fully equipped kitchen area •Spacious garden (150 m2) • Private and secure parking. •Terrace with breakfast area • 1 full bathroom • Ambient lighting •Heaters and fan • Screen with Roku •High speed Wi-Fi • Clean, private street with surveillance •Quiet and safe area

Guest favorite
Home in San José Tetel
4.92 out of 5 average rating, 25 reviews

5 minutes from the High-Performance Deportiva de Alto Rendimiento (High Performance Sports Complex)

Stay in this spacious and cozy house, ideal for you or your family, in a quiet, safe, and private residential development in the heart of Apizaco. Central location to explore iconic places such as: Huamantla, La Trinidad, La Malinche volcano, Cacaxtla archaeological zone, Firefly Sanctuary, Barca de la Fe and more! 5 minutes from Plaza de Toros and Ciudad Deportiva, and 8 minutes from downtown Apizaco. “Book now and enjoy a most pleasant stay”

Guest favorite
A spacious sleeping area features a wooden four-poster bed with soft gray bedding. Natural light fills the room through large windows, framed by minimalistic light fixtures. A small table and chair are positioned beside the window, offering a serene view of the surrounding greenery.
Loft in Santa Agueda
4.98 out of 5 average rating, 140 reviews

Exclusive Penthouse, Val`Quirico

Perfect romantic escape for couples or solo travellers looking to unwind and relax. The private penthouse apartment is just a five minute walk away from the heart of Val’Quirico, includes free parking and a fully equipped kitchen. The private terrace is perfect for romantic dinners, star gazing and has amazing views of the Malinche mountain where the sunrises. An ideal space to recharge, celebrate love and enjoy an unforgettable experience.

Top guest favorite
A bright living area is showcased with large windows covered by sheer curtains, allowing natural light to fill the space. A circular marble coffee table sits atop a soft area rug, accompanied by two chocolate brown armchairs and a dark sectional sofa. A television is positioned on a wooden stand.
Apartment in Apizaco
4.98 out of 5 average rating, 51 reviews

A complete and centrally located apartment

Excellent full apartment with privileged location in Apizaco Tlax. Ideal for short and long stays, located on the second floor of a building, in front of the only Soriana in the center, 5 minutes from the city's main park and with a fast route to the main roads. It has two full bedrooms, a full kitchen, a full bathroom and a living room with all amenities. Free street parking or a boarding service a block and a half away at no extra cost.

Guest favorite
Cottage in Santa Cruz Tlaxcala
4.92 out of 5 average rating, 39 reviews

Spectacular Ranch 5 minutes from Trinidad IMSS

Bring the whole family to this fantastic place, enjoy the tranquility of nature, without leaving aside the fun both outside and inside, with the bar, pool table or movie night! Relax at this ranch located in the municipality of Santa Cruz Tlaxcala. Enjoy the views from the hillside, walk around the property, or visit the La Trinidad Holiday Center. At night, immerse yourself in the incredible views of the galaxy in the open field.

Guest favorite
A decorative stone fountain features a multi-tiered design, with flowing water cascading down. Surrounding the fountain are vibrant red poinsettias in black planters, creating a welcoming focal point in the outdoor space.
Home in Apizaco Centro
4.94 out of 5 average rating, 215 reviews

AMAZING "CASA CARMELA" in the center of Apizaco

THIS SPACE FOLLOWS AIRBNB'S ADVANCED CLEANING PROTOCOL. Cozy and wonderful 1-story house, located in downtown Apizaco. Excellent location a few blocks from restaurants, bars, convenience stores, cinema, among others. The house has excellent essential services (Internet, Netflix), as well as a garage (5.0 meters long) for a small or medium-sized sedan or SUV. We accept small or medium-sized pets; large pets with prior approval.

Guest favorite
An open living space features a modern dining area with a glass table and dark chairs. A cozy seating area includes a gray sofa, while a mounted television is positioned against a textured accent wall. Bright artwork and plants add lively touches to the environment.
Apartment in Apetatitlán
4.93 out of 5 average rating, 68 reviews

Comfortable apartment in Tlaxcala

Excellent cozy apartment in a quiet area. Enjoy a good space equipped with all the amenities, ideal for family vacations or business trips. Discover it and feel at home. Located 5.4 km from the historic center (12 min), 2.8 km from the Altiplano Zoo and Gran Patio Tlaxcala (6 min). Nearby you will have convenience stores and food outlets. Quiet area.

Guest favorite
Home in Santa María Atlihuetzian
5 out of 5 average rating, 13 reviews

Malintzi Garden House | Pet Friendly. We invoice

This beautiful accommodation is ideal for weekends with family, friends or as a couple, large garden with barbecue for gatherings and children's games, everyone will enjoy the beautiful view of the Malintzi, in addition to all the comforts of a charming, relaxing place full of harmony with nature.

Popular amenities for Santa Cruz Tlaxcala vacation rentals

  1. Airbnb
  2. Mexico
  3. Tlaxcala
  4. Santa Cruz Tlaxcala