
Vacation rentals in Santa Cruz Tlaxcala
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Top-rated vacation rentals in Santa Cruz Tlaxcala
Guests agree: these stays are highly rated for location, cleanliness, and more.

Beautiful house with a large garden
Less than two hours from Mexico City, spacious and cozy house very well lit with large garden, ideal for resting in a peaceful place, meeting and living with family or friends, appreciate the majesty of the Malinche, have breakfast or roast a meat outdoors, even play volleyball or basketball, or relax in the jacuzzi. Strategically located 20 minutes from downtown Tlaxcala and less than an hour from tourist attractions such as El Santuario de las Luciérnagas and Val'Quirico.

Beautiful house with a garden. Close to downtown Tlax.
Comfortable and quiet stay with a large garden. Just 10 minutes from downtown Tlaxcala. The space: • Entire private house • Fully equipped kitchen area •Spacious garden (150 m2) • Private and secure parking. •Terrace with breakfast area • 1 full bathroom • Ambient lighting •Heaters and fan • Screen with Roku •High speed Wi-Fi • Clean, private street with surveillance •Quiet and safe area

Piacere loft Val'Quirico. Bed, Jacuzzi & Coffee
Lotf Piacere features a unique design and a private Jacuzzi. In addition (we can rent you a car for 4 people) This space is located in the heart of Val' Quirico, in an excellent location—you can go out and find charming restaurants, cafes, shops, bars, etc., just a few steps away. In special cases, we can rent you a car for four people so you can explore the pre-Hispanic region, such as Cacaxtla, Xochitecalt and Tlaxcala City, which is 20–30 minutes away.

La Cabaña
Experience the serenity of nature at its finest! Discover our luxurious cabin with a unique style, located just 15 minutes from the majestic La Malinche National Park and 20 minutes from the vibrant center of Tlaxcala. Immerse yourself in breathtaking landscapes, surrounded by fruit trees and forests that invite you to tranquility and relaxation. Come and live the best experience of contact with nature in our incomparable home! Invoices are issued.

5 minutes from the High-Performance Deportiva de Alto Rendimiento (High Performance Sports Complex)
Stay in this spacious and cozy house, ideal for you or your family, in a quiet, safe, and private residential development in the heart of Apizaco. Central location to explore iconic places such as: Huamantla, La Trinidad, La Malinche volcano, Cacaxtla archaeological zone, Firefly Sanctuary, Barca de la Fe and more! 5 minutes from Plaza de Toros and Ciudad Deportiva, and 8 minutes from downtown Apizaco. “Book now and enjoy a most pleasant stay”

Exclusive Penthouse, Val`Quirico
Perfect romantic escape for couples or solo travellers looking to unwind and relax. The private penthouse apartment is just a five minute walk away from the heart of Val’Quirico, includes free parking and a fully equipped kitchen. The private terrace is perfect for romantic dinners, star gazing and has amazing views of the Malinche mountain where the sunrises. An ideal space to recharge, celebrate love and enjoy an unforgettable experience.

Spectacular Ranch 5 minutes from Trinidad IMSS
Bring the whole family to this fantastic place, enjoy the tranquility of nature, without leaving aside the fun both outside and inside, with the bar, pool table or movie night! Relax at this ranch located in the municipality of Santa Cruz Tlaxcala. Enjoy the views from the hillside, walk around the property, or visit the La Trinidad Holiday Center. At night, immerse yourself in the incredible views of the galaxy in the open field.

AMAZING "CASA CARMELA" in the center of Apizaco
THIS SPACE FOLLOWS AIRBNB'S ADVANCED CLEANING PROTOCOL. Cozy and wonderful 1-story house, located in downtown Apizaco. Excellent location a few blocks from restaurants, bars, convenience stores, cinema, among others. The house has excellent essential services (Internet, Netflix), as well as a garage (5.0 meters long) for a small or medium-sized sedan or SUV. We accept small or medium-sized pets; large pets with prior approval.

Giuseppe, Tuscan Charming Loft in Val'quirico
Enjoy a unique getaway in this Tuscan-inspired loft, ideal for unwinding and relaxing. A warm and cozy space where every detail is designed for your relaxation: from a comfortable bed to a perfect atmosphere for enjoying your morning coffee. Located in the heart of Val'Quirico, it is ideal for couples, friends, or travelers looking for a unique, peaceful, and charming experience.

Comfortable apartment in Tlaxcala
Excellent cozy apartment in a quiet area. Enjoy a good space equipped with all the amenities, ideal for family vacations or business trips. Discover it and feel at home. Located 5.4 km from the historic center (12 min), 2.8 km from the Altiplano Zoo and Gran Patio Tlaxcala (6 min). Nearby you will have convenience stores and food outlets. Quiet area.

Comfortable apartment with an excellent view
Cozy, quiet and luxurious apartment, ideal for family and friends who come to visit "located 3 minutes from the Trinidad Vacation Center, 5 minutes from Apizaco Centro, 15 minutes at the foot of Volcán la Malinche and 20 minutes from Huamantla" Excellent view and location ! Don't think about it and take advantage of your stay !

Adobe cabin in Tlaxcala, Pet Friendly
Disconnect from the hustle and bustle of the city and breathe fresh air at Casa Los Capulines! Beautiful cabin built with bio-construction techniques, located in San Dionisio, Yauhquemehcan, Tlaxcala, a very quiet town 5 minutes from Apizaco and 15 minutes from downtown Tlaxcala, where you can enjoy the countryside.
Popular amenities for Santa Cruz Tlaxcala vacation rentals
Other great vacation rentals in Santa Cruz Tlaxcala

Apartment near downtown.

House near IMSS Trinidad

Casa Lozada – Spacious and beautiful home in Apizaco

Ideal place in Tlaxcala

Midnight Oasis

A complete and centrally located apartment

Comfortable apartment (Netflix included)

Beautiful Loft, near the socket and carousel
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