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Vacation rentals in Santa Cruz Mixtepec

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Top-rated vacation rentals in Santa Cruz Mixtepec

Guests agree: these stays are highly rated for location, cleanliness, and more.

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Top guest favorite
A dining area features a small round table surrounded by four upholstered chairs. A vase of sunflowers adds a pop of color to the table's center. In the background, a kitchen with modern appliances is visible, along with an art piece hanging on the wall.
Apartment in Oaxaca de Juárez
4.96 out of 5 average rating, 136 reviews

Apartment with terrace and view – Xochimilco neighborhood

Bienvenidos a su hogar en el barrio más antiguo y pintoresco de Oaxaca, nuestro departamento de 2 habitaciones combina la tranquilidad de Xochimilco con todas las comodidades para que solo se preocupen por disfrutar. *Detalles que importan: cocina equipada, café local de cortesía, agua purificada, Wi-Fi de alta velocidad. *Terraza privada para relajarte tras un día intenso. *Ubicación premium, camina entre las calles empedradas, acueductos, talleres. Estamos a 12 minutos a pie de Santo Domingo.

Top guest favorite
Loft in Oaxaca Centro
4.94 out of 5 average rating, 103 reviews

Casa Besos loft 1, tub and garden, St Domingo area

Discover your refuge in the heart of Oaxaca. Casa Besos offers lofts and villas with vernacular design, steps from the Santo Domingo Temple, with the comfort of a boutique hotel and the authentic charm of the city. Want to relax? Enjoy your outdoor tub under the stars. Would you rather explore? All the folklore, gastronomy, art and culture are just a few steps away.” "DON'T FORGET TO SEE MY OTHER BOUTIQUE ACCOMMODATIONS IN MY PROFILE, (LOFTS and VILLAS) steps from the Santo Domingo temple".

Top guest favorite
A vibrant Alebrije sculpture featuring bright orange and red colors is displayed on a wooden base. A textured rug in varied hues provides a warm foundation beneath it. In the background, a potted fern adds a touch of greenery, complementing the artistic decor.
Loft in Oaxaca Centro
4.89 out of 5 average rating, 221 reviews

Alebrije Loft, Center of the City, "Merced house"

Bonito Mini Loft, ubicado a cuatro calles de la plaza principal de la ciudad. En la zona mas tranquila del centro histórico. Disfruta de la comida tradicional de la ciudad, de los lugares mas emblemáticos del centro, Santo Domingo, catedral, mercados tradicionales, museos, comida tradicional, a solo unas calles del alojamiento. En la casa observaras otros alojamientos y viajeros que al igual que tu disfrutan de la tranquilidad de la casa. Disfruta la hermosa decoración con artistas locales.

Guest favorite
A serene temazcal room is featured, showcasing curved stone walls gently illuminated by candles. A small potted plant and a decorative drum are placed within the space, creating a calming atmosphere. The room is designed for relaxation and holistic experiences.
Home in Oaxaca
4.92 out of 5 average rating, 225 reviews

Casa MaryFer

Casa MaryFer is located 1.5 km from Oaxaca City's International Airport and 10.3 km from the city's Zócalo and Santo Domingo church. What sets it apart is that it is located in the tranquility of a picturesque village, as well as the friendliness of its people and their traditions. The Mexican-style decoration offers its guests the comfort and friendliness of "being at home", in addition to having a temazcal bath for 6 people and therapeutic massages (at an extra cost and by appointment).

Guest favorite
The spacious living area is characterized by warm tones and textured walls, featuring an inviting sofa next to a striking coffee table. A kitchenette, adorned with simple cabinetry, includes essential appliances. Lush plants are positioned throughout, enhancing the tranquil ambiance.
Apartment in Oaxaca Centro
4.94 out of 5 average rating, 148 reviews

Magical Restored house, KS Bed/AC in Oaxaca heart

Step into CASA Espíritu Fuego, where the spirit of Oaxaca is reimagined through thoughtful design and handcrafted beauty. Earthy textures, native clay, and woven textiles tell stories in every corner. Located just 3 blocks from Santo Domingo, the city’s best galleries, fine dining, and cultural gems unfold at your doorstep. You’ll be immersed in the city soul where art, cuisine, and vibrant culture await. A curated stay for the discerning traveler seeking authenticity and beauty. .

Superhost
An A-frame design is displayed, featuring a spacious sleeping area on a wooden platform. A large window offers a view of the agave fields and mountains. Soft lighting highlights the warm tones of the wooden interior, creating a comfortable ambiance.
Cabin in Teotitlan Del Valle
4.95 out of 5 average rating, 132 reviews

Cabin 1 on the mezcal route

Cabin with sleeping platform and terrace viewpoint located on the mezcal route. While you rest, enjoy the scenery of the agave fields, mountains, and stars. Outside there is a shared kitchen that you can use to prepare your own food. The cabin is located on the international highway that connects the capital with tourist places such as Tlacolula de Matamoros, Mitla or Hierve el Agua. All kinds of public transportation pass by on the road: bus, van, or taxi.

Guest favorite
A spacious living area features natural light flooding in through large glass doors, enhancing the connection to the outdoors. Comfortable seating arrangements include soft floor cushions, a cozy sofa, and a wooden coffee table, complemented by greenery visible through the windows.
Home in Santa Cruz Amilpas
4.96 out of 5 average rating, 51 reviews

Casa Zá - Modern home, Gardens, A/C

Architect-designed home, a collaboration with architect Daniel Lopez Salgado. The thoughtfully planned layout, soaring ceilings and abundant light create a calming atmosphere, perfect for unwinding after a day of exploring. 15-minute taxi/car ride from Oaxaca Centro, our home offers a perfect balance of tranquility and accessibility. While you won't find tourist spots nearby, you'll be able to find flavors of Oaxaca at local family owned restaurants nearby.

Top guest favorite
Apartment in Oaxaca Centro
4.92 out of 5 average rating, 497 reviews

The House of Don Mario /November 20. Downtown

Located on one of Oaxaca's main streets, "La casa de don Mario" is close to everything Oaxaca is a walkable city, and having a lodging space downtown is a great plus. Staying in an old house that is part of the city's history is a privilege. Decorated with furniture made from parts of the old oil factory and rebuilt while bearing in mind the idea of a vintage atmosphere, the house has many features to enjoy Oaxaca and its heart full of flavor and color.

Guest favorite
A cozy living area is presented with a wooden dining table beside a sofa. Natural light enters through large windows, highlighting the rustic wooden beams on the ceiling. A chair is positioned near the door, adding to the inviting ambiance of the space.
Bungalow in San Andrés Huayápam
4.89 out of 5 average rating, 124 reviews

Perfect Peacefull Bungalow

Beautifully decorated rustic bungalow nested in a quiet location 20 minutes drive from downtown Oaxaca. In this peaceful location you will be able to enjoy spectacular views while finding everything you need within walking distance: local restaurants, nature hikes and abarrotes. Our bungalow is the perfect place for those seeking to spend a few days in the Oaxaca Valley, getting to know all the beautiful pueblos while staying away from tourist crowds.

Guest favorite
A studio space is presented featuring a spacious bed adorned with colorful striped linens. Light filtered through sheer curtains brightens the room, enhancing the earthy tones of the decor. In the background, an open kitchen area can be seen, equipped with a dining table and cactus plants.
Loft in Oaxaca Centro
4.78 out of 5 average rating, 325 reviews

Sweet Studio downtown

Nice little studio with air conditioning two blocks from the Zócalo of the city. Walk to all attractions in 10 minutes. The place is nicely furnished with simple Oaxacan charm. Everything is provided. Please note that since it is in a restaurant area there might be some noise at night... We do have double glazed windows, however it is not recommended for light sleepers (hence we kept the reasonable price for this list)...

Top guest favorite
A wooden desk with a matching chair is positioned against a warm, terracotta wall. Above the desk, a round mirror reflects natural light. A framed floral painting adds a pop of color, enhancing the rustic decor of the space.
Apartment in Guelaguetza
4.94 out of 5 average rating, 393 reviews

Apartment with balcony and breakfast included

An authentic home where you'll feel like family. Wake up to homemade breakfasts on our terrace overlooking the mountains and let yourself be guided by local tips. Ideal location: a quiet neighborhood just a 10-minute walk from the city center. Enjoy comfortable beds, fast Wi-Fi, and unparalleled warmth. A space full of color, light, and peace, designed for experiencing Oaxaca like a local.

Guest favorite
Loft in Santa Lucía del Camino
5 out of 5 average rating, 6 reviews

From Marijo

Located on the rooftop of our home, this charming apartment is the ideal retreat for one couple or up to three people looking for rest and privacy in Oaxaca. Enjoy wonderful views of the Cerro de Oaxaca, unforgettable sunsets and an atmosphere full of calm. Every detail is designed for you to live a comfortable and special stay. A loft for perfect rest and relaxation

Popular amenities for Santa Cruz Mixtepec vacation rentals

  1. Airbnb
  2. Mexico
  3. Oaxaca
  4. Santa Cruz Mixtepec