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Hotel vacation rentals in Santa Cruz Island

Find and book unique hotel rentals on Airbnb

Top-rated hotel rentals in Santa Cruz Island

Guests agree: these hotel rentals are highly rated for location, cleanliness, and more.

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A well-lit room features two spacious Queen beds with decorative pillows. A wooden desk with a TV is positioned against the wall. A window with sheer curtains allows natural light to enter, while air conditioning is visible on the side wall.
Hotel room in Puerto Ayora
4.78 out of 5 average rating, 118 reviews

Amplia y Espaciosa Habitación Twin en Santa Cruz

Aquí encontraras comodidad en una linda habitación con dos camas Queen, amplia, iluminada y ventilada, con TV y aire acondicionado nuevo, baño privado con agua caliente y productos de higiene biodegradables. Puedes tomar sol junto a la piscina, disfrutar de un café Galapagueño o un cálido té y agua filtrada disponible para ti libremente en nuestra área social. Sera un gusto ser tus anfitriones y ayudarte en lo que necesites, nos encargaremos de hacerte sentir como en casa.

Superhost
The living area features orange sofas and a wooden coffee table on a light rug. A dining table with bright chairs is positioned nearby, while a hammock hangs against the wall. Natural light enters through large windows adorned with curtains.
Casa particular in Puerto Ayora
4.91 out of 5 average rating, 32 reviews

Jardin de Galápagos

Nuestra casa ha sido diseñada pensando en el respeto y la conservación del entorno natural único de las Islas Galápagos. hemos preparado una guía personalizada con recomendaciones locales, desde restaurantes con delicias autóctonas hasta lugares secretos que solo los lugareños conocen. "Jardín de Galápagos" les espera para ofrecerles comodidad, lujo y una conexión auténtica con este paraíso natural. Permítannos ser su anfitrión en esta experiencia inolvidable!

Superhost
Shared hotel room in Puerto Ayora
4.67 out of 5 average rating, 3 reviews

Share Room, Hostal Tintorera, Galapagos-Santa Cruz

En Tintorera Guest House ofrecemos habitaciones compartidas ideales para quienes desean una estadía cómoda y accesible en Puerto Ayora, Isla Santa Cruz. Cada cama cuenta con colchón cómodo, ropa de cama y almohada. Los huéspedes disponen de baños compartidos con limpieza regular, lockers individuales para mayor seguridad, aire acondicionado o ventilador (según la categoría) y WiFi en las áreas comunes.

Superhost
A comfortable sleeping area features two spacious beds, each adorned with neatly arranged towels. Light streams in through large windows, illuminating the room's contemporary decor, which includes an artistic wall piece and simple furnishings.
Hotel room in Puerto Ayora

Hostal Patty's House Galápagos comodidad

Incluye desayuno variado para cada día No te pierdas esta gran promoción Disfruta del fácil acceso a tiendas y restaurantes populares desde este encantador espacio para quedarte. Incluye desayuno variado para cada día No te pierdas esta gran promoción Habitación confortable Tu mejor aventura comienza aquí, porque nos preocupamos de hacer tu visita un recuerdo inolvidable.

Superhost
A cozy space is shown with a table adorned by a small flower arrangement, complemented by two chairs. Beyond, a sleeping area is visible featuring a warm-toned bedspread on a spacious bed and artwork displayed on the wall, softly illuminated by overhead lighting.
Hotel room in Puerto Ayora
5 out of 5 average rating, 3 reviews

The Galapagos Pearl Hotel - Patio Room #2

Patio Room with Garden View (#2) The Galapagos Pearl is a charming bed and breakfast retreat in a quiet, residential neighborhood in Puerto Ayora, Santa Cruz Island. It is located one and a half blocks away from Charles Darwin Avenue, the main tourist street of downtown. It is a convenient walking distance from the heart of town and a block and a half away from the sea.

Guest favorite
A calm outdoor area is visible, featuring hammocks strung between wooden posts. Comfortable seating options, including a wooden table and chairs, enhance the space. Lush greenery and colorful plants surround the area, providing a serene atmosphere. Bright blue skies and sunlight contribute to the overall warmth.
Private room in Puerto Ayora
4.87 out of 5 average rating, 187 reviews

Galapagos M Glory

Galapagos M Glory, stay in the heart of Puerto Ayora—just steps from the Fish Market, bars, restaurants, travel agencies, the main port, and the Charles Darwin Station. 🌿 Relax in our quiet garden with hammocks, and enjoy comforts like AC, hot showers, and fast Starlink Wi-Fi. We provide fresh towels, soap, and daily cleaning—everything to make you feel at home.

Guest favorite
A comfortable room features a spacious bed with a patterned cover and additional towels neatly arranged. A water cooler is positioned in the corner, beside a wooden chair and a small table. Natural light filters through sheer curtains, brightening the space.
Private room in Puerto Ayora
4.78 out of 5 average rating, 147 reviews

Sleeping room in Puerto Ayora

The room is comfortable and well located. It has internet, air conditioning and a private bathroom. It is also close to shops, restaurants and pharmacies, one block from the fishermen's pier. It is a little noisy at night because of the cars since it is a main avenue. The neighborhood is very safe and in general the people are very friendly.

Guest favorite
Private room in Puerto Ayora
4.89 out of 5 average rating, 19 reviews

Alojamiento tranquilo con vistas

Habitación con baño privado completo, aire acondicionado, wifi y todos los servicios básicos para disfrutar de su visita. La casa está ubicada en un lugar tranquilo desde donde se puede disfrutar de hermosas vistas de toda la bahía de Puerto Ayora, La Lobería y Santa Fe. Relájate en este lugar único, rústico y acogedor

A private balcony is depicted, showcasing a table and chairs positioned against a white wall. The sky is bright with scattered clouds, and palm trees are visible in the background, framing a view of nearby buildings.
Casa particular in Puerto Ayora

Casa familiar Galápagos con terraza privada

Tu familia estará cerca de todo cuando te quedes en este alojamiento céntrico. Zona tranquilo puede caminar a pie a los restaurantes bares que están en la avenida Charles Darwin a 300 metros . Al frente de la casa hay una panadería y desayunos deliciosos.

Guest favorite
An outdoor terrace is featured with blue chairs surrounding a wooden table. A vibrant mural of marine life adorns the wall, while a brick grill is positioned nearby. Lush greenery and potted plants surround the space, enhancing the inviting atmosphere.
Private room in Puerto Ayora
4.93 out of 5 average rating, 40 reviews

Nelyza's Suites & Adventure

We welcome you to experience the life of a true Galapagenian in suites that are close to the port and the accessible to all the beautiful nature. Like true locals, we know the best places to visit, and this is what we like to share with you.

The room features two spacious beds dressed in white linens, complemented by blue accents. A wooden table and chair are positioned near a closet without doors, while a split air conditioning unit is mounted above. Light enters from the doorway leading to a dark hallway.
Hotel room in Puerto Ayora
4.62 out of 5 average rating, 29 reviews

Darwin Hostal in Galápagos

Disfruta del fácil acceso al Malecón, Muelle turístico, restaurantes populares, desde este encantador espacio para quedarte. Enjoy the easy access to the Harbour, turistic pier, popular restaurants, from this lovely place to stay.

Guest favorite
Private room in Puerto Ayora
5 out of 5 average rating, 15 reviews

Departamento privado en Galapagos, Santa Cruz

2 double rooms with private bathroom in my house . You have also access to the kitchen and a washer.

Popular amenities for Santa Cruz Island hotel rentals

Kitchen
Wifi
Pool
Free parking on premises
Air conditioning

Family-friendly hotel rentals

Superhost
A well-lit swimming pool is featured in the foreground, surrounded by a patio area with colorful flags strung overhead. The building displays large windows on either side, and a hammock is visible on the wall, creating a sense of leisure and relaxation.
Hotel room in Puerto Ayora

The Galapagos Pearl Hotel - Room #12

Superhost
A room features three comfortable beds with simple linens. A mirror is mounted on a wall, and two wooden nightstands are positioned beside the beds. Natural light enters through a window, and an air conditioning unit is visible on the wall.
Hotel room in Puerto Ayora

Private Triple Room - Santa Cruz, Galápagos

A spacious room features wooden beams across the ceiling, enhancing the bright atmosphere. A cozy bed with a blue throw is complemented by a desk and chairs near a window, allowing natural light to fill the space. A television is mounted on the wall.
Hotel room in Puerto Ayora
4.61 out of 5 average rating, 75 reviews

Hermosa Suite con Terraza en Puerto Ayora

Superhost
An outdoor seating area is framed by greenery and features a small table with chairs. The room entrance is visible, showcasing a spacious bed with green linens. Natural light filters through the windows, enhancing the inviting atmosphere of the space.
Hotel room in Puerto Ayora

The Galapagos Pearl Hotel - Patio Room #1

A serene walkway meanders through a lush garden, featuring potted plants and flowering shrubs. White walls frame the pathway, while trees provide natural shade. The scene is enhanced by soft greenery and the tranquility of the area.
Hotel room in Puerto Ayora
4.7 out of 5 average rating, 10 reviews

Habitación en Galápagos, Darwin Hostal

A spacious bed is adorned with an orange accent pillow and a white pillow. The bedding features a light-colored throw that complements the wooden headboard, which displays a simple design. Warm light filters softly through a nearby window.
Private room in EC
4.62 out of 5 average rating, 34 reviews

Hostal Estrella de Mar (Double Room).

Superhost
An open layout features a spacious bed with crisp white linens and a bright artwork depicting ocean waves on the wall. A sleek desk and chair are positioned near a window, with additional details including a small refrigerator and natural light streaming in from the window.
Hotel room in Puerto Ayora
4.64 out of 5 average rating, 11 reviews

Galapagos Dreams Matrimonial

Superhost
A well-lit room features two independent beds draped in vibrant green covers, accentuated by decorative swan towel arrangements. A small seating area includes a couch and a round table with two chairs. Large windows provide natural light, and a television is positioned for viewing.
Hotel room in Puerto Ayora
4.74 out of 5 average rating, 31 reviews

Galapagos Dreams Doble

Hotel rentals with a pool

Superhost
A welcoming patio area is presented, featuring a small table with green cushions and two wooden chairs. Through an arched doorway, a bedroom is visible, accented by framed artwork depicting marine life. Natural light filters through the windows, illuminating the interplay of indoor and outdoor spaces.
Hotel room in Puerto Ayora
4.67 out of 5 average rating, 3 reviews

The Galapagos Pearl Hotel- Patio Room #3

A sea lion is positioned on a rocky shore, facing upwards. The backdrop features a vibrant blue sea and distant mountains, along with patches of green seaweed scattered along the beach. The scene reflects a serene natural environment.
Hotel room in Puerto Ayora
4.33 out of 5 average rating, 3 reviews

Galapagos Homes

Superhost
A cozy outdoor seating area features a green and white hammock suspended between two walls, inviting relaxation. An open door leads to a sleeping space with a blue bedspread, while a colorful wall art piece adds a splash of brightness to the white walls.
Hotel room in Puerto Ayora
5 out of 5 average rating, 5 reviews

The Galapagos Pearl Hotel- Room #11

A sparkling blue swimming pool is surrounded by lush greenery and tropical plants. Comfortable lounge chairs are arranged nearby, offering a space for relaxation. A rock waterfall feature adds a touch of natural beauty, enhancing the outdoor setting beneath a bright sky.
Hotel room in Bellavista
4.75 out of 5 average rating, 4 reviews

Oferta de temporada

A bright room features two spacious beds with orange and white accents. Large windows with heavy green curtains allow natural light to brighten the space. A wooden desk is situated against the wall, complemented by warm wooden cabinetry and coastal artwork.
Hotel room in Puerto Ayora
4.54 out of 5 average rating, 13 reviews

Habitación Twin Familiar

A bright sleeping area features two beds, one with a vibrant teal cover and the other in a deep blue hue. A decorative arrangement of swan-shaped towels with flowers is displayed on the teal bed, enhancing the welcoming ambiance of the room.
Hotel room in Puerto Ayora
4.33 out of 5 average rating, 3 reviews

Hostal España - Habitación Doble

Superhost
A view of the hotel’s exterior showcases a staircase leading to upper levels, flanked by lush green plants and flowering bushes. Arch-shaped windows and wooden doors create a welcoming facade. A covered seating area is visible, offering a tranquil spot amidst the greenery.
Hotel room in Puerto Ayora
4.81 out of 5 average rating, 59 reviews

The Galapagos Pearl Hotel- Balcony Room #6

An aerial view captures a large, inviting pool complemented by a circular jacuzzi. Surrounding lounges are positioned near the water, while lush greenery frames the area. The tile deck is interspersed with terracotta-roofed structures, blending seamlessly with the tranquil surroundings.
Hotel room in El Garrapatero
4.64 out of 5 average rating, 11 reviews

Enchanted Lodge

Hotel rentals with a patio

A spacious bedroom features a king-size bed adorned with decorative pillows and a light blanket. Soft lighting enhances the modern décor, complemented by a framed artwork of a coastal scene. Nearby, a mini-refrigerator is discreetly positioned within the room.
Hotel room in Puerto Ayora

Standard Room at Hotel Santa Fe

A serene courtyard is framed by vibrant green plants, with a stone planter at the center. The walls are adorned with mosaic tiles, and a large window in the background offers a glimpse of the indoor space. A balcony with wooden railing is visible above.
Hotel room in Puerto Ayora
4.54 out of 5 average rating, 13 reviews

Habitación sencilla en GPS

A well-lit room features two beds, one with a simple white bedspread accented by a blue sash. The floor is tiled with a geometric pattern. A decorative mirror reflects the space, while a small wooden table is visible beside one bed.
Hotel room in Puerto Ayora

Alojamiento Santa Cruz - HAB. DOBLE

A bright bedroom features a spacious bed adorned with a white quilt and a red accent. Tall windows dressed with sheer curtains allow natural light to fill the room, enhancing the fresh ambiance. A small potted plant adds a touch of greenery.
Hotel room in Puerto Ayora
4.63 out of 5 average rating, 19 reviews

Hermosa Habitación matrimonial frente al mar.

A spacious room features a large wooden bed adorned with decorative towels shaped into swans. Above the bed, a vibrant artwork of a turtle adds a focal point. Natural light fills the room, highlighting the sleek, tiled floor and minimalist design.
Hotel room in Puerto Ayora

Hotel Galapagos Santa Cruz

An inviting entrance is framed by a wooden gate, providing a view of a pathway lined with greenery. The pathway leads up to a spacious building adorned with large windows and a welcoming atmosphere, surrounded by tropical plants and palm trees.
Hotel room in Bellavista

SUYMARecolodge, Lobo

A compact bedroom features a double bed with a turquoise throw draped across it, complemented by a rolled towel. A small nightstand is positioned beside the bed, and a television is mounted on the wall. Neutral-toned tiles cover the floor.
Hotel room in Puerto Ayora

Habitación matrimonial en el centro de pto. ayora

A spacious room is visible through an archway, featuring two beds with light bedding. Decorative wall art complements the wooden headboards. Natural light enters through windows with ornate frames, illuminating the tiled floor and a small chair in the corner.
Hotel room in Puerto Ayora

Spacious & Comfotable Twin Room with Pool

Destinations to explore

  1. Airbnb
  2. Ecuador
  3. Galápagos
  4. Santa Cruz Island
  5. Hotel rentals