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Vacation rentals in Santa Ana

Find and book unique accommodations on Airbnb

Quick stats about vacation rentals in Santa Ana

  • Total vacation rentals

    Explore 90 vacation rentals in Santa Ana

  • Nightly prices starting at

    Santa Ana vacation rentals start at G$6,277 GYD per night before taxes and fees

  • Verified guest reviews

    Over 1,210 verified reviews to help you choose

  • Family-friendly vacation rentals

    50 properties offer extra space & kid-friendly amenities

  • Pet-friendly vacation rentals

    Find 50 rentals that welcome pets

  • Rentals with dedicated workspaces

    20 properties have a dedicated workspace

  • Wi-Fi availability

    40 of Santa Ana vacation rentals include wi-fi access

  • Popular amenities for guests

    Guests love Kitchen, Wifi, and Pool across Santa Ana rentals

  • 4.7 Average rating

    Santa Ana stays receive an average rating of 4.7 out of 5 from guests

Top-rated vacation rentals in Santa Ana

Guests agree: these stays are highly rated for location, cleanliness, and more.

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Top guest favorite
Home in Santa Ana
4.93 out of 5 average rating, 42 reviews

House with heated pool for families and groups

Enjoy tranquility and comfort in this beautiful and spacious house in Balneario Santa Ana, 2 blocks from the beach, with a heated pool and a heat pump that reaches 40 degrees Celsius (104 degrees Fahrenheit) in winter. Equipped for 8-10 people. Two bedrooms, 6 single beds, one double bed, plus a sofa bed in the living room. Located 1 block from the main street, where two COPSA lines pass. Supermarket, butcher shop and bakery 3 blocks away. Ideal for vacations with family or friends, birthdays or bachelor parties.

Top guest favorite
Home in Pan de Azucar
5 out of 5 average rating, 34 reviews

"Arrayanes de las Ánimas" Chakra

Located in the heart of the Sierras de las Ánimas, this country house is perfect to disconnect and enjoy nature. It sleeps up to 7 people and features 3 bedrooms, 2 bathrooms (one en suite), a barbecue, an outdoor Nordic bath, a fire pit under the stars, and a pergola with dining and lounge space. It also has a kids’ outdoor play area. Surrounded by native plants and wildlife, it's ideal for hiking and relaxing with family or friends. Come experience the Uruguayan countryside like never before!

Guest favorite
Home in Santa Ana
4.93 out of 5 average rating, 14 reviews

Beachfront house with a view of the hills

Beautiful house on the Rambla with a unique view of the ocean and the hills of Piriapolis. The location allows you to see the sunrise and sunset over the sea in summer. The main house has a living room with a large window facing the beach and a high-performance wood-burning stove. Semi-integrated kitchen with exit to the barbecue. The barbecue is spacious and covered and has a grill and a wood oven for pizza. 15 minutes from Piriapolis and 30 minutes from Punta del Este.

Superhost
A modern cabin is set on a gently sloping hillside, surrounded by natural vegetation. The structure features a wooden exterior and large windows, allowing for ample natural light. A distant cabin can be seen on the hill, further integrating the property with the surrounding landscape.
Place to stay in Nueva Carrara
5 out of 5 average rating, 10 reviews

Piedra de las Ánimas Cabin

Cozy cabin with a queen bed and a living-dining room integrated with the kitchen, ideal for relaxing in spacious and bright spaces. Its large windows offer a privileged view of the mountains, connecting you with nature. The kitchen is equipped with an under-counter refrigerator, a stove and everything you need for cooking (dishes and basic utensils). It includes a full bathroom, a wood-burning stove, a deck with a pergola and a Paraguayan hammock to enjoy the outdoors.

Top guest favorite
Tiny home in Sauce de Portezuelo
4.98 out of 5 average rating, 91 reviews

BondiHouse - Converted Bus

Welcome to BondiHouse! A space we built with lots of love and care. ** Adults-only accommodation ** Perfect for romantic getaways 😍 This tiny house is ideal for disconnecting, relaxing, and enjoying the peace of nature and all its comforts. We invite you to experience a stay full of unique details and amenities, thoughtfully designed with a boutique feel—where you won’t miss a thing. Every corner was crafted with love so you feel right at home… or even better. ✨

Guest favorite
A sunshade is positioned over a deck area, providing a view of rolling hills and a serene body of water. Two lounge chairs are visible in the distance, and colorful cushions rest on the deck, creating a relaxed outdoor setting.
Cottage in Pan de Azucar
4.93 out of 5 average rating, 14 reviews

Casa Mara Sierra- 3

A unique place with style! The house has an area of 40 meters. It is located in a prime location high in the mountains, surrounded by beautiful scenery. It is part of a complex consisting of three houses in total. The house is for two people. It offers a spacious bedroom with an en-suite bathroom and a modern fully integrated kitchen. In addition, it has a high-performance wood-burning stove. Outside it has its private deck with a barbecue grill.

Top guest favorite
An open living area is presented with large windows allowing natural light to fill the space. A seating area features a wooden couch with orange cushions and a coffee table. A dining table with wicker chairs and a decorative bowl completes the inviting setting.
Home in Playa Verde
4.97 out of 5 average rating, 105 reviews

Playa Verde is 70 meters from the sea. Panoramic.

House 70 meters from the beach, on a street with access to the beach. Bright, spacious, airy, with ocean views, sunset and sunrise to enjoy every day. Two bedrooms and a bathroom on the ground floor. Upstairs, integrated kitchen, dining room and living room plus roofed terrace. Air conditioning in all rooms. Outdoor shower with hot water. More roofed space with grill. Located on 300 meters of land, with several floors and native trees growing.

Top guest favorite
A sunlit living area features expansive glass doors that offer views of the surrounding greenery. Two wicker chairs are arranged around a wooden coffee table, while a comfortable bench with striped pillows provides additional seating. A television is positioned for easy viewing.
Home in Punta Colorada
4.97 out of 5 average rating, 176 reviews

Oceanfront house in Punta Colorada

Overlooking the ocean. Very well lit. It has two bedrooms on the lower floor (with a crib available for the little ones) and a kitchen, living-dining room, and a terrace with a grill on the upper floor. A/C and high-performance wood-burning stove. The double room has air conditioning and a French window that opens onto the front of the house. The rooms have a closet. The house is located just 100 meters from the beach (across the street).

Guest favorite
A charming house features a sunlit exterior painted in warm yellow, complemented by brown stone accents. A tiled roof adds character, while a wooden fence encloses a lush garden area. Nearby greenery and flowers enhance the inviting atmosphere of this peaceful retreat.
Home in Santa Ana
4.87 out of 5 average rating, 30 reviews

I WANT IT, I CAN DO IT, AND I DESERVE IT!!

Our house is brand new and meets disinfection requirements for an excellent stay. Welcome to MARCOR, located in a strategic area, a minute from the splendor of Piriápolis and about 50 km from Punta Del Este. We have natural waters that make it extremely unique and unparalleled. Santa Ana links the rustic with the harmonious where native animals of the fauna coexist. We also have OSE and UTE connections, which is no small thing.

Superhost
Home in Balneario Argentino
4.86 out of 5 average rating, 28 reviews

House with enclosed jacuzzi, pool and barbecue grill

Private ✨ Heated Salt Water Pool October-May ♨️ Private Jacuzzi to enjoy and relax in Roofed 🍽️ grill and outdoor furniture 🚗 Parking 📶 WiFi 📺 -Smart TV 40” with Netflix, Disney+ Full 👩‍🍳 kitchen microwave, coffee maker, toaster, blender, blender and electric jug ❄️ A/C 🛏️ Bed linens and towels included 🏐 Volleyball Court 🧺 Washing machine 🚿 Outdoor shower. 💇‍♀️ Hair dryer 👕 Iron 🧴shampoo, rinse cream

Top guest favorite
A sunlit outdoor area features a calming pool surrounded by wooden lounge chairs, positioned on a deck of pale wood. Lush greenery and swaying palm-like plants add a touch of nature, with a clear blue sky in the background.
Cabin in Punta Negra
4.97 out of 5 average rating, 139 reviews

House with pool near the sea.

House with a private heated pool, just 30 meters from the sea in Barra de Portezuelo. Ideal for relaxing all year round, with a fenced-in garden, barbecue, and a quiet setting. It features Wi-Fi, air conditioning in the living room, a wood-burning stove, and parking. Perfect for couples or families seeking privacy, comfort, and proximity to the beach. *We accept pets. *Heated pool available from September to mid-April.

Guest favorite
A bright living area is highlighted by large windows offering views of lush greenery and the ocean. Two comfortable armchairs and a sofa are arranged around a coffee table, while a dining table for four sits nearby. Floral decor adds a touch of elegance.
Home in Araminda
4.94 out of 5 average rating, 96 reviews

Beautiful house with ocean views

Relax in this unique and quiet getaway. Fall in love with this place like we did. Enjoyable in summer for its beaches and also in winter for its tranquility, incredible views and its bio diversity that surprises you when you see hares, apereases, birds of all kinds including vultures and eagles. We think about enjoying it year-round. Accommodation for adults (except for teenagers 13 years of age and older)

Popular amenities for Santa Ana vacation rentals

When is the best time to visit Santa Ana?

MonthJanFebMarAprMayJunJulAugSepOctNovDec
Avg. priceG$15,064 GYDG$14,645 GYDG$13,390 GYDG$12,762 GYDG$10,670 GYDG$12,762 GYDG$12,762 GYDG$12,972 GYDG$12,972 GYDG$12,972 GYDG$12,972 GYDG$14,227 GYD
Avg. temp23°C22°C21°C18°C14°C11°C11°C12°C13°C16°C19°C21°C

Frequently Asked Questions

  • Are there family-friendly vacation rentals in Santa Ana?

    Santa Ana has more than 50 family-friendly stays. Amenities on the property may include high chairs, travel cribs, or strollers.

  • How much does it cost to stay in house rentals in Santa Ana?

    Experience the best of Santa Ana with our house rentals, starting at about $30 per day, before taxes and fees. Embrace comfort and style while staying within your budget in your home away from home.

  • Are there pet-friendly vacation rentals in Santa Ana?

    Four-legged friends are welcome in Santa Ana. Choose from more than 50 vacation rentals for guests traveling with pets.

  • Are there vacation rentals with a dedicated workspace in Santa Ana?

    Yes! Work meets play with ease at over 20 vacation rentals in Santa Ana featuring dedicated workspaces. Stay connected and productive in your home away from home.

  • Do house rentals in Santa Ana have air conditioning?

    Absolutely! We offer over 30 house rentals with air conditioning in Santa Ana. Enjoy a tailored experience with all the comforts you desire.

  • Do house rentals in Santa Ana have a kitchen?

    Absolutely! We offer over 60 house rentals with a kitchen in Santa Ana. Enjoy a tailored experience with all the comforts you desire.

  • Do house rentals in Santa Ana have wifi?

    Absolutely! We offer over 30 house rentals with wifi in Santa Ana. Enjoy a tailored experience with all the comforts you desire.

  • Do house rentals in Santa Ana have free parking?

    Absolutely! We offer over 50 house rentals with free parking in Santa Ana. Enjoy a tailored experience with all the comforts you desire.

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