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Vacation rentals in San Luis

Find and book unique accommodations on Airbnb

Top-rated vacation rentals in San Luis

Guests agree: these stays are highly rated for location, cleanliness, and more.

Guest favorite

Cottage in Apoyo Lagoon

4.9 out of 5 average rating, 72 reviews

Casa Castillo: Million Dollar View Of Lake Apoyo

This property is truly one of a kind. We’d love for you to experience both the breath taking view outside and the Spanish revival elements of the house inside. Located on the northwest rim of an extinct volcano in the Apoyo Lagoon Natural Reserve, the view is...spectacular! Looking out from the Castillo terrace, in front of you lies the ancient volcanic Apoyo lake. In the distance, you can see the Mombacho volcano, Lake Nicaragua, the city of Granada and the Isletas ,and sometimes Concepcion.

Aug 20 – 27

G$41,828 GYD per night
Guest favorite

Home in Granada

4.92 out of 5 average rating, 12 reviews

Stunning modern colonial home.

A Beautiful luxury colonial style house with a modern take on the traditional designs. Garden courtyard, swimming pool and all mod cons. Two large bedrooms with ensuite bathrooms and one guest toilet downstairs. Open plan kitchen/dining area, large Sala with double storey roof featuring traditional reed roofing. There are spacious courtyards with many different chill out areas around the pool. Garage space for two cars. Situated in central Granada, it is a 5 minutes walk from main square.

May 13 – 20

G$20,520 GYD per night
Superhost

Home in Granada

4.83 out of 5 average rating, 413 reviews

Beautiful Colonial House w Pool in Center

Villa 'Casa Blanca' in the center of old town Granada, located just 2 blocks from the buzzing main street La Calzada, with restaurants & nightlife. Colonial meets modern, you'll love staying in this oasis because of the spacious living and full kitchen, the private pool area, 2 Air-conditioned Bedrooms with 2 Private bathrooms and 1 Mezzanine Bedroom. Both the living area and bedroom have Netflix TVs. The house sleeps 10. We have fast and reliable WIFI internet. The reviews say it all!

Sep 12 – 19

G$20,280 GYD per night

Popular amenities for San Luis vacation rentals

Other great vacation rentals in San Luis

Guest favorite

Home in Veracruz

4.88 out of 5 average rating, 42 reviews

Cozy Pool Side House

Feb 28 – Mar 7

G$19,164 GYD per night
Guest favorite

Home in Managua

4.95 out of 5 average rating, 21 reviews

Cozy Townhouse in Managua!

Jul 1 – 8

G$22,638 GYD per night
Superhost

Guesthouse in Ticuantepe

4.93 out of 5 average rating, 92 reviews

Nice Vacation Guest House,Managua

Jun 29 – Jul 6

G$10,625 GYD per night
Guest favorite

Home in Managua

5.0 out of 5 average rating, 24 reviews

Apt in house/residential, independent, 3 pers.

Jun 18 – 25

G$7,496 GYD per night
Superhost

Home in Granada

4.84 out of 5 average rating, 81 reviews

Fabulous Colonial Home in Old Town Granada

Aug 22 – 29

G$30,918 GYD per night
Guest favorite

Home in Apoyo Lagoon

4.94 out of 5 average rating, 87 reviews

Luxury Waterfront @ Laguna de Apoyo

Sep 7 – 14

G$61,632 GYD per night
Superhost

Home in Granada

4.84 out of 5 average rating, 103 reviews

Casa La Sultana - Your luxury home away from home.

Jul 10 – 17

G$68,246 GYD per night
Superhost

Vacation home in Pochomil Viejo

4.8 out of 5 average rating, 20 reviews

Pacific Paradise

Feb 16 – 23

G$88,197 GYD per night
Guest favorite

Home in Gran Pacifica Resort

4.95 out of 5 average rating, 20 reviews

Casa Costa Blanca

Sep 2 – 9

G$58,714 GYD per night
Guest favorite

Guesthouse in Laguna de Apoyo

5.0 out of 5 average rating, 39 reviews

Casita Café - Lakefront Love Nest with Kitchen

Nov 2 – 9

G$12,047 GYD per night
Superhost

Apartment in Gran Pacifica Resort

5.0 out of 5 average rating, 7 reviews

Condo 113 Gran Pacifica

Oct 6 – 13

G$27,268 GYD per night
Guest favorite

Home in San Rafael

5.0 out of 5 average rating, 33 reviews

Casa Tranqui

Mar 18 – 25

G$20,697 GYD per night

Destinations to explore

  1. Airbnb
  2. Nicaragua
  3. Managua Region
  4. Tipitapa
  5. San Luis