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Vacation rentals in Distrito San Francisco

Find and book unique accommodations on Airbnb

Top-rated vacation rentals in Distrito San Francisco

Guests agree: these stays are highly rated for location, cleanliness, and more.

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Guest favorite
A scenic view of rolling hills under a colorful sky at sunset. Shades of orange, pink, and purple blend, creating a vibrant horizon. Lush trees are scattered across the landscape, adding a touch of greenery to the terrain.
Cottage in Olá
4.94 out of 5 average rating, 16 reviews

Casa de Campo en Olá, ríos, cascadas, Los Picachos

Finca La Terapia hace honor a su nombre, se encuentra entre las montañas del pintoresco pueblo de Olá de Penonomé, en la cual podrás desconectarte del ajetreado día a día de la ciudad. Cuenta con 42 Hectáreas privadas para explorar la naturaleza. El distrito de Olá, se caracteriza por tener lo mas hermosos paisajes Naturales entre los que podemos mencionar, Los Chorros de Olá, Chorros las Mesitas, Cerros los Picachos, Rio San Antonio, Balneario Brujas, entre otros a muy poco minutos de la Finca.

Guest favorite
Tiny home in El Copé, La Pintada
5 out of 5 average rating, 7 reviews

Serena Lodge & Camping - El Copé

Escape to Serena Lodge, a cozy mountain cabin tucked among pine trees in El Copé, Panama. Wake up to birdsong, stunning valley views, and total privacy—just minutes from waterfalls (Las Yayas, Tigrero, Santa Maria, El Harino river, Rio Grande, Chorro Grande) and the Omar Torrijos National Park. Perfect for couples, families, friends, remote workders and nature lovers seeking fresh air, and a true disconnect in the mountains. 🌧️ Rainy Season (May–November) ☀️ Summer Season (December–March)

A modern cabin with a unique architectural design is showcased, featuring an orange and stone exterior. A covered porch area provides shelter and views of the surrounding greenery. A gray vehicle is parked in front, illustrating easy access to this welcoming space.
Cabin in Santa Fe
4.71 out of 5 average rating, 14 reviews

Cabaña Rincón de Cielo

Disfruta de la naturaleza y una experiencia con estilo en este alojamiento ubicado en el centro de Santa Fe y cerca de Rios, Cascadas y montañas. La propiedad tiene hermosas vistas a las montañas y a un pequeño lago. La propiedad puede alojar más de dos huéspedes previa coordinación y por un precio adicional por persona. La cabaña es elegante y cuanta con una habitación con A/C , lavandería, cosina y sala/comedor. El uso de la cocina y la lavandería tiene un costo adicional de $10.00

A cozy corner is shown with a light-toned futon, paired with a small wooden table and two modern chairs. Natural light enters through two windows, complementing the warm wooden paneling on one wall.
Condo in Panama City
4.67 out of 5 average rating, 30 reviews

Departamento 2E - BEST place in town.

Accessible apartment in the heart of Santiago, located 300m from the Central Bus Station and within walking distance of supermarkets and businesses. With good distribution of space, fresh and illuminated and with all basic services. The apartments provide a harmonious balance in the middle of the rush characteristic of the city, perfect for stays of families, friends, professionals, couples.

Superhost
A tranquil garden scene is depicted, featuring a winding pathway of smooth stones and pebbles. Surrounding areas are adorned with various flowering plants and a small pond, enhancing the peaceful ambiance. Lush greenery is visible in the background, contributing to the serene atmosphere.
Farm stay in Santa Fe
4.89 out of 5 average rating, 300 reviews

Santa Fe villa with a espectacular view

Spectacular contemporary style villa surrounded by local flowers and woods. The villas design enhances the relationship with the outside environment with panoramic windows which are found in the dining room and kitchen, this offers an awesome view of the mountains and green flora. The villa is located in a organic quiet farm, with abundant vegetation and great presence of birds.

Superhost
Cottage in Santa Fe
5 out of 5 average rating, 4 reviews

k* Casa Matilde | 2BR Santa Fe Retreat by River

Escape to Casa Matilde, a renovated 100 m² home in Santa Fe de Veraguas. With 2 bedrooms and 3 beds (1 queen & 2 twins), it’s perfect for families or remote workers. Enjoy a bright living room, modern bath with hot water, A/C, and fast Starlink Wi-Fi. Relax by the private creek, explore the river just 200 m away, and take in mountain views—all with total privacy and comfort.

Superhost
A small dining area is featured with a round table and two folding chairs. Large windows offer views of lush greenery outside, while sheer white curtains partially filter natural light.
Apartment in Santiago
4.88 out of 5 average rating, 8 reviews

d'rosas apartamentos 3PB

Descubre la comodidad en nuestro acogedor alojamiento en el corazón de Santiago, Veraguas. A solo 5 minutos a pie del centro de la ciudad, disfrutarás de un espacio bien equipado que incluye todas las comodidades necesarias para una estancia relajante. Ideal para explorar la cultura local y descansar después de un día de aventuras. ¡Te esperamos!

Superhost
Cabin in Calobre
4.71 out of 5 average rating, 24 reviews

La Yeguada - Forest Point Cabin

Lleva a toda la familia a este fantástico lugar con muchas zonas para divertirse, totalmente equipada cabaña de campo con cocina amplia, sala de estar con acceso a televisión, hamacas, refrigerador, estufa, agua caliente y todo lo que necesitas para pasar un buen momento alejado del ruido y convivir con la naturaleza.

Guest favorite
A spacious living area is surrounded by large windows, offering panoramic views of the lush landscape. Comfortable seating is arranged in a circular layout, adorned with colorful cushions. A central coffee table is complemented by decorative plants and a warm wooden floor enhances the inviting ambiance.
Farm stay in Santa Fe
5 out of 5 average rating, 9 reviews

Mansion en Granja Orgánica Piscina Climatizada

Relájate con toda la familia y amigos hasta 30 personas en esta acogedora casa en una granja organica con animales, sembradios, pesca de tilapia, café , rios, contamos con piscina Climatizada, terraza techada de 120 mts para que celebres tus ocasiones especiales.

A cozy sleeping area features a spacious bed, surrounded by natural wooden walls made from woven materials. A wooden dresser holds neatly arranged towels, with soft lighting creating a serene ambiance. A textured area rug complements the wooden floor.
Cabin in Santa Fe
4.79 out of 5 average rating, 53 reviews

Cabane vue sur la riviere

Détendez-vous dans ce logement unique et tranquille. Goutez l'experience unique de la nature dans votre chambre et salon : -) Cabane confortable. (glamping). Acces a la riviere. Vue panoramique. tres calme, tres zen. Massages et osteophathie sur demande.

Guest favorite
A contemporary cabana is nestled among lush greenery, showcasing a unique stone accent wall. Large windows offer expansive views of the natural surroundings, complemented by a covered terrace that invites outdoor relaxation.
Home in Las Trancas
4.91 out of 5 average rating, 22 reviews

Cabana Vergara Santa Fe

Kick back and relax on this 2 acre ( 1 hectare) private mountain side property, on the Santa Maria River. Equipped with all the amenities you will need to make your stay a home away from home!

Guest favorite
A single-story house features an arched entry with decorative windows. The front porch is equipped with seating, surrounded by greenery. A paved driveway leads to the home, providing access for vehicles, while the roof offers ample shade.
Home in Santiago
4.92 out of 5 average rating, 12 reviews

Casa Nuevo San Juan

Acceso facil desde la Panamericana. Es un área céntrico tiene disponibilidad de supermercado, farmacia, restaurante, hospital.

Popular amenities for Distrito San Francisco vacation rentals