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Vacation rentals in De Soto

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Top-rated vacation rentals in De Soto

Guests agree: these stays are highly rated for location, cleanliness, and more.

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Guest favorite
Home in De Soto
5 out of 5 average rating, 8 reviews

De Soto Bay Retreat

This home has just undergone a complete head to toe remodel. Everything is new and fresh from the electrical and plumbing, paint, beds, linens and appliances. This two story house with a view of the river has an indoor/plumbed fish and game cleaning station. Walking distance to Pike's Bar, Bright Spot Diner and the gas/bait station. Parking has space for 1 truck & trailer in front of the neighbors, 1 truck & small trailer (boat) in front of our home, and 1 truck & trailer in the driveway.

Superhost
A hot tub is positioned on a deck, offering views of the Mississippi River and surrounding greenery. The water reflects sunlight, creating a calming atmosphere. The scene includes a bridge in the distance under a partly cloudy sky.
Cabin in De Soto
4.88 out of 5 average rating, 80 reviews

Eagles Nest Hideaway w/outdoor hot tub

This cozy property that overlooks the Mississippi River on 1/2 acre is your next perfect getaway. Having 2 separate buildings to split the group makes this location ideal for families , friend gatherings & fishing trips. Main cabin has 2 bedrooms & 1 bath as well as a full kitchen and hot tub. Garage has an upstairs loft with mini kitchenette , 2 queen size beds, small deck overlooking river & another bathroom. - Hot tub overlooks the Mississippi River & outdoor gas grill in screened in porch

Top guest favorite
The exterior of a modern house is framed by lush green trees, showcasing a multi-level design. A spacious deck is visible with seating arrangements. A smaller building with a dark facade is located nearby, suggesting additional space or utility.
Cabin in De Soto
5 out of 5 average rating, 70 reviews

Driftless Cabin - Sauna, Firepit, BBQ

With central proximity to Viroqua, LaCrosse and Prairie du Chien, experience the Driftless region in style & comfort. Nestled in the woods, 5 mins from the Mississippi, enjoy peace and relaxation with friends and family. Lay back in the sauna and sweat out your stress. Sit by the firepit, share stories and gaze at the star-studded skies. Listen to music in the sunroom and watch birds dart across the backyard. Sway in the hammock and let the sun warm your body. Visit and return rejuvenated.

Guest favorite
Cabin in De Soto
4.81 out of 5 average rating, 64 reviews

Cozy Ridge Retreat

Welcome to the beauty of nature along the Mississippi! This cabin has it all from modern amenities and an authentic log cabin feel to the beautiful soaring views of the Mississippi. You and your guests will enjoy the convenient location, only 12 minutes from Lansing, IA or 7 minutes to the nearest boat landing. Take in the wildlife that frequently passes through the peaceful wooded hillside on the large covered screened porch. Once you arrive you will agree the drive was well worth the visit!

Top guest favorite
A deck with a circular wooden table and two chairs overlooks the water, with trees framing the view of the expansive landscape. The soft hues of dusk provide a serene backdrop to the scene, highlighting the natural beauty of the surroundings.
Cabin in Ferryville
5 out of 5 average rating, 28 reviews

Great River Cabin

Welcome to the mighty Mississippi River, the famous Driftless Area and Great River Cabin. This brand new 2 bedroom 1 bath cabin is fully equipped for a relaxing getaway including 2 private bedrooms, bathroom with walk-in shower, toilet and vanity, kitchenette with stove, full size fridge, microwave and peninsula for dining. There is a TV and futon for extra sleeping space. The jewel of the property is the deck running the full length of the cabin with expansive views of the Mighty Mississippi.

Guest favorite
Cabin in De Soto
4.9 out of 5 average rating, 151 reviews

Barn On The Ridge / HOT TUB / Sleeps 6

Kick back & relax in this cozy, stylish cabin with beautiful river views during all seasons. Enjoy evening dinners on the screened in porch, sip your coffee from the upper deck & unwind in a luxurious hot tub! This loft style cabin was crafted in 2020 & has sleeping space for up to 6 guests, featuring a king bed, full size bed & full size futon. You’ll be minutes from De Soto & Lansing area and only 30 minutes to the La Crosse area! See all 7 properties with Hot Tubs at Rentals Justin Time.

Top guest favorite
Cabin in Ferryville
4.99 out of 5 average rating, 100 reviews

Aspenshire Cabin: A Nod to English Charm

Aspenshire Cabin is nestled in a valley overlooking a private stream. The Driftless Region is known for its rolling hills and beautiful landscapes. This newly remodeled cabin stands in striking contrast to the woods surrounding it. Inspired by the cozy + sophisticated vibes of Old English Charm, a nod to this design style is evident throughout. Guests are welcomed into a space curated for rest and relaxation, whether through a quiet retreat for the arts or a getaway with family and friends.

Top guest favorite
An outdoor deck features a cedar hot tub and seating area, surrounded by natural landscapes. In the background, a fire pit is set up with chairs, while a picturesque sunset casts a warm glow over the serene surroundings.
Cabin in Viola
4.99 out of 5 average rating, 171 reviews

Secluded cabin,cedar sauna & hot tub,outdoorshower

360 views in the middle of 75 organic acres, no neighbors in site. Outdoor Cedar hot tub & infrared sauna, heated outdoor shower, two king loft bedrooms, full kitchen, back deck with custom hibachi grill to watch sunrise and front covered deck to watch sunset. Indoor/ outdoor fire places. Wildflower fields.We try to give our couples priority booking when they rent our wedding venue 2 miles down the hill (Chapters on the Horizon) that is why we do not instant book.

Guest favorite
A park model home is positioned on a stone terrace, surrounded by lush greenery. Large windows offer expansive views of the surrounding landscape. A wooden deck with seating is visible, extending the living space outdoors, with a tranquil atmosphere conveyed by the scenic backdrop.
Cabin in De Soto
4.96 out of 5 average rating, 148 reviews

Paradise Point sleeps 2 Hot Tub

1 bedroom 1 bath with loft. Cozy home where you can see Paradise. This memorable place is anything but ordinary. Views for miles of the Mississippi River, bluff tops and you can soar with the Eagles. What a place to relax in the newly added hot tub while you enjoy the view in what is call "God's Country". This is promised to be a one of a kind view. The Deck with comfortable outdoor seating Located in the heart of WIsconsin's Driftless Region.

Guest favorite
A red cabin with a covered porch is seen, featuring a sign that reads 'RIVER VIEW.' The porch is furnished with seating and surrounded by greenery. Nearby, another red cabin structure is visible, set against a backdrop of trees and a clear blue sky.
Cabin in De Soto
4.93 out of 5 average rating, 14 reviews

De Soto Riverview Cabins # 4

Cabin #4 is a two bedroom cabin, fully furnished with kitchen and bath, featuring two (2) queen beds. You'll love the exposed beams and vaulted ceilings. Max occupancy is 4 adults/children. Located in the village of DeSoto, WI. The area offers numerous activities including year round fishing, hiking, seasonal hunting, snowmobile trails, motorcycle riding, bicycling trails, wineries, breweries, Amish Bakeries.

Top guest favorite
A rustic cabin with log siding is set against a clear blue sky. The front porch is covered and features steps leading up to the entrance. Lush greenery surrounds the cabin, with a gravel pathway leading to it. The structure includes two gabled roofs.
Cabin in De Soto
4.96 out of 5 average rating, 79 reviews

Cedar Lookout a top the Mississippi River.

Cedar Lookout a rustic cabin sits above the Mississippi River & is a great place to relax and get away from it all. This quiet little cabin can be a reading place, romantic or cozy get away, family adventure or fishermen's retreat. Just a few miles from the river, small town shopping, a hiking park across the river, fresh air and wildlife.

Guest favorite
Home in De Soto
4.98 out of 5 average rating, 49 reviews

Mississippi Escape

Completely remodeled 3-bedroom house in Desoto, WI. Located right off the beautiful, Mississippi. Perfect for a peaceful getaway or outdoor activities. Great for fishing/boating and outdoor recreation. Desoto is located about 5 miles from Lansing, IA, and 30 miles south of La Crosse, WI.

Popular amenities for De Soto vacation rentals

  1. Airbnb
  2. United States
  3. Wisconsin
  4. Vernon County
  5. De Soto