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Vacation rentals in De Soto

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Top-rated vacation rentals in De Soto

Guests agree: these stays are highly rated for location, cleanliness, and more.

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Top guest favorite
A cozy cabin is situated among lush greenery, featuring a spacious deck that extends from the entrance. The gravel driveway leads up to the cabin, surrounded by trees and wild foliage, creating a serene, natural atmosphere.
Cabin in Westby
4.99 out of 5 average rating, 140 reviews

Nature's Nest

Unwind and immerse yourself in nature at this cozy cabin overlooking Timber Coulee Creek. Large living room windows and a spacious deck provide you with a bird’s eye view of the rippling river and many types of wild life. Deer amble through the property; eagles soar and keep an eagle eye on everything. Turkeys, squirrels, coons, and myriad of birds go about their business in this serene environment. Trout fishing is an excellent pastime for those who care to cast a line. Rest, at Nature’s Nest.

Superhost
A hot tub is positioned on a deck, offering views of the Mississippi River and surrounding greenery. The water reflects sunlight, creating a calming atmosphere. The scene includes a bridge in the distance under a partly cloudy sky.
Cabin in De Soto
4.87 out of 5 average rating, 78 reviews

Eagles Nest Hideaway w/outdoor hot tub

This cozy property that overlooks the Mississippi River on 1/2 acre is your next perfect getaway. Having 2 separate buildings to split the group makes this location ideal for families , friend gatherings & fishing trips. Main cabin has 2 bedrooms & 1 bath as well as a full kitchen and hot tub. Garage has an upstairs loft with mini kitchenette , 2 queen size beds, small deck overlooking river & another bathroom. - Hot tub overlooks the Mississippi River & outdoor gas grill in screened in porch

Top guest favorite
The exterior of a modern house is framed by lush green trees, showcasing a multi-level design. A spacious deck is visible with seating arrangements. A smaller building with a dark facade is located nearby, suggesting additional space or utility.
Cabin in De Soto
5 out of 5 average rating, 67 reviews

Driftless Cabin - Sauna, Firepit, BBQ

With central proximity to Viroqua, LaCrosse and Prairie du Chien, experience the Driftless region in style & comfort. Nestled in the woods, 5 mins from the Mississippi, enjoy peace and relaxation with friends and family. Lay back in the sauna and sweat out your stress. Sit by the firepit, share stories and gaze at the star-studded skies. Listen to music in the sunroom and watch birds dart across the backyard. Sway in the hammock and let the sun warm your body. Visit and return rejuvenated.

Top guest favorite
A charming farmhouse is nestled among lush greenery, surrounded by tall trees. The two-story structure features a gabled roof and a covered front porch. Natural landscaping, including shrubs and grass, frames the house, creating a serene and private atmosphere amidst the forested hills.
Cabin in Gays Mills
4.98 out of 5 average rating, 380 reviews

Driftless Region Cabin/ Stream and Sauna

Settle into a quaint farmhouse nestled in a valley in the rolling, forested hills of the Driftless Region. Start your day with a cup of local coffee on the front porch. Go on a long walk or bike ride, then return to the cottage to cook, play board games, listen the record collection or visit Viroqua (25 minutes) for a farm-to-table 5-star dinner, or check out local music. Build a warm fire outdoors/ warm up by the gas stove indoors, or go down to the stream for a sauna by the cool water creek.

Guest favorite
An outdoor fire pit area is surrounded by four comfortable chairs on a concrete pad. Stacked logs are neatly arranged beside the fire pit, and verdant grass and trees provide a serene natural backdrop.
Home in De Soto
4.92 out of 5 average rating, 76 reviews

Cozy Sportsman's Hideaway

Enjoy the outdoors in this cozy getaway. Sportsman will love the close to 14 acres of hunting, hiking hiking and Coulee Creek which is a class 1 trout stream just 1/2 mile down the road (shown in pictures). The cabin boasts a large deck for enjoying the woodland views. On those chilly evenings warm yourself beside the outdoor fire pit. Why compromise when this cabin offers a pleasant stay decorated with rustic decor, comfortable Hickory furniture, modern amenities and peaceful surroundings.

Guest favorite
Cabin in De Soto
4.9 out of 5 average rating, 148 reviews

Barn On The Ridge / HOT TUB / Sleeps 6

Kick back & relax in this cozy, stylish cabin with beautiful river views during all seasons. Enjoy evening dinners on the screened in porch, sip your coffee from the upper deck & unwind in a luxurious hot tub! This loft style cabin was crafted in 2020 & has sleeping space for up to 6 guests, featuring a king bed, full size bed & full size futon. You’ll be minutes from De Soto & Lansing area and only 30 minutes to the La Crosse area! See all 7 properties with Hot Tubs at Rentals Justin Time.

Top guest favorite
Cabin in Ferryville
5 out of 5 average rating, 94 reviews

Aspenshire Cabin: A Nod to English Charm

Aspenshire Cabin is nestled in a valley overlooking a private stream. The Driftless Region is known for its rolling hills and beautiful landscapes. This newly remodeled cabin stands in striking contrast to the woods surrounding it. Inspired by the cozy + sophisticated vibes of Old English Charm, a nod to this design style is evident throughout. Guests are welcomed into a space curated for rest and relaxation, whether through a quiet retreat for the arts or a getaway with family and friends.

Top guest favorite
A park model home is positioned on a stone terrace, surrounded by lush greenery. Large windows offer expansive views of the surrounding landscape. A wooden deck with seating is visible, extending the living space outdoors, with a tranquil atmosphere conveyed by the scenic backdrop.
Cabin in De Soto
4.96 out of 5 average rating, 140 reviews

Paradise Point sleeps 2 Hot Tub

1 bedroom 1 bath with loft. Cozy home where you can see Paradise. This memorable place is anything but ordinary. Views for miles of the Mississippi River, bluff tops and you can soar with the Eagles. What a place to relax in the newly added hot tub while you enjoy the view in what is call "God's Country". This is promised to be a one of a kind view. The Deck with comfortable outdoor seating Located in the heart of WIsconsin's Driftless Region.

Top guest favorite
A welcoming entrance features a spacious patio surrounded by green lawns and decorative plants. Comfortable seating arrangements invite relaxation, while large windows provide views of the river. A pathway leads to the front door, highlighting the property’s connection to nature.
Home in Genoa
4.98 out of 5 average rating, 43 reviews

River Road Haven

Welcome to River Road Haven, a peaceful 3BR/2BA retreat Looking over the Mississippi River in Genoa, WI. Enjoy stunning sunsets, bald eagle sightings, and passing barges from your private deck. Just minutes from the fishing dam and hatchery, it's a perfect spot for anglers and nature lovers. Relax in comfort with river views, a full kitchen, and cozy living spaces. Unwind, reconnect, and experience the beauty of river life on the Great River Road.

Guest favorite
A red cabin with a covered porch is seen, featuring a sign that reads 'RIVER VIEW.' The porch is furnished with seating and surrounded by greenery. Nearby, another red cabin structure is visible, set against a backdrop of trees and a clear blue sky.
Cabin in De Soto
4.9 out of 5 average rating, 10 reviews

De Soto Riverview Cabins # 4

Cabin #4 is a two bedroom cabin, fully furnished with kitchen and bath, featuring two (2) queen beds. You'll love the exposed beams and vaulted ceilings. Max occupancy is 4 adults/children. Located in the village of DeSoto, WI. The area offers numerous activities including year round fishing, hiking, seasonal hunting, snowmobile trails, motorcycle riding, bicycling trails, wineries, breweries, Amish Bakeries.

Top guest favorite
A rustic cabin with log siding is set against a clear blue sky. The front porch is covered and features steps leading up to the entrance. Lush greenery surrounds the cabin, with a gravel pathway leading to it. The structure includes two gabled roofs.
Cabin in De Soto
4.96 out of 5 average rating, 74 reviews

Cedar Lookout a top the Mississippi River.

Cedar Lookout a rustic cabin sits above the Mississippi River & is a great place to relax and get away from it all. This quiet little cabin can be a reading place, romantic or cozy get away, family adventure or fishermen's retreat. Just a few miles from the river, small town shopping, a hiking park across the river, fresh air and wildlife.

Guest favorite
The single-story house features a subtle brick exterior and a sloped metal roof. A landscaped garden with a small sign is visible in the front yard, surrounded by a green lawn. Large windows let in natural light, adding to the welcoming appearance.
Home in De Soto
4.98 out of 5 average rating, 47 reviews

Mississippi Escape

Completely remodeled 3-bedroom house in Desoto, WI. Located right off the beautiful, Mississippi. Perfect for a peaceful getaway or outdoor activities. Great for fishing/boating and outdoor recreation. Desoto is located about 5 miles from Lansing, IA, and 30 miles south of La Crosse, WI.

Popular amenities for De Soto vacation rentals

  1. Airbnb
  2. United States
  3. Wisconsin
  4. Vernon County
  5. De Soto