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Vacation rentals in De Soto

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Top-rated vacation rentals in De Soto

Guests agree: these stays are highly rated for location, cleanliness, and more.

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Top guest favorite
A cozy cabin is situated among lush greenery, featuring a spacious deck that extends from the entrance. The gravel driveway leads up to the cabin, surrounded by trees and wild foliage, creating a serene, natural atmosphere.
Cabin in Westby
4.99 out of 5 average rating, 128 reviews

Nature's Nest

Unwind and immerse yourself in nature at this cozy cabin overlooking Timber Coulee Creek. Large living room windows and a spacious deck provide you with a bird’s eye view of the rippling river and many types of wild life. Deer amble through the property; eagles soar and keep an eagle eye on everything. Turkeys, squirrels, coons, and myriad of birds go about their business in this serene environment. Trout fishing is an excellent pastime for those who care to cast a line. Rest, at Nature’s Nest.

Superhost
A hot tub is positioned on a deck, offering views of the Mississippi River and surrounding greenery. The water reflects sunlight, creating a calming atmosphere. The scene includes a bridge in the distance under a partly cloudy sky.
Cabin in De Soto
4.86 out of 5 average rating, 74 reviews

Eagles Nest Hideaway w/outdoor hot tub

This cozy property that overlooks the Mississippi River on 1/2 acre is your next perfect getaway. Having 2 separate buildings to split the group makes this location ideal for families , friend gatherings & fishing trips. Main cabin has 2 bedrooms & 1 bath as well as a full kitchen and hot tub. Garage has an upstairs loft with mini kitchenette , 2 queen size beds, small deck overlooking river & another bathroom. - Hot tub overlooks the Mississippi River & outdoor gas grill in screened in porch

Top guest favorite
An aerial view shows a modern wooden cabin surrounded by greenery. A spacious deck features seating areas, while a firepit is positioned nearby. A hammock is visible to the side, and a small shed is present in the yard, enhancing the rustic charm of the outdoor space.
Cabin in De Soto
5 out of 5 average rating, 61 reviews

Driftless Cabin - Sauna, Firepit, BBQ

With central proximity to Viroqua, LaCrosse and Prairie du Chien, experience the Driftless region in style & comfort. Nestled in the woods, 5 mins from the Mississippi, enjoy peace and relaxation with friends and family. Lay back in the sauna and sweat out your stress. Sit by the firepit, share stories and gaze at the star-studded skies. Listen to music in the sunroom and watch birds dart across the backyard. Sway in the hammock and let the sun warm your body. Visit and return rejuvenated.

Top guest favorite
A charming farmhouse is nestled among lush greenery, surrounded by tall trees. The two-story structure features a gabled roof and a covered front porch. Natural landscaping, including shrubs and grass, frames the house, creating a serene and private atmosphere amidst the forested hills.
Cabin in Gays Mills
4.98 out of 5 average rating, 373 reviews

Driftless Region Cabin/ Stream and Sauna

Settle into a quaint farmhouse nestled in a valley in the rolling, forested hills of the Driftless Region. Start your day with a cup of local coffee on the front porch. Go on a long walk or bike ride, then return to the cottage to cook, play board games, listen the record collection or visit Viroqua (25 minutes) for a farm-to-table 5-star dinner, or check out local music. Build a warm fire outdoors/ warm up by the gas stove indoors, or go down to the stream for a sauna by the cool water creek.

Top guest favorite
A serene view of the Mighty Mississippi River is captured during sunset. Soft hues of orange and purple fill the sky, while the landscape is framed by lush green trees and gentle mists rising from the water, creating a tranquil atmosphere.
Home in Lynxville
4.86 out of 5 average rating, 268 reviews

Highland Hideaway

A cozy, secluded two bedroom cabin located in the driftless region with incredible views of the Mighty Mississippi!!! If you’re looking for peace & quiet, beautiful sunsets, watching wildlife or barges cruise this is your place. Only 20 minutes from Wyalusing or pikes peak state park, The Effigy Mounds (Indian Burial Grounds)and Historic Villa Louis. This beautiful cabin centers you 30 miles from amazing hiking, fishing, hunting and nature for a weekend of disconnecting from busy life.

Guest favorite
Cabin in De Soto
4.9 out of 5 average rating, 144 reviews

Barn On The Ridge / HOT TUB / Sleeps 6

Kick back & relax in this cozy, stylish cabin with beautiful river views during all seasons. Enjoy evening dinners on the screened in porch, sip your coffee from the upper deck & unwind in a luxurious hot tub! This loft style cabin was crafted in 2020 & has sleeping space for up to 6 guests, featuring a king bed, full size bed & full size futon. You’ll be minutes from De Soto & Lansing area and only 30 minutes to the La Crosse area! See all 7 properties with Hot Tubs at Rentals Justin Time.

Superhost
A log cabin is nestled among trees, showcasing a rustic design with a sloped roof and wooden siding. A front porch with several chairs is visible, along with an adjacent path leading to a gravel driveway. Autumn foliage adds vibrant color to the surroundings.
Cabin in De Soto
4.9 out of 5 average rating, 118 reviews

Murph's: Cozy 3BR/2BA cabin w/ hot tub + fireplace

Murph's Hideaway is a log cabin located high on the bluffs overlooking the Mississippi River valley. This three-bedroom/two-bathroom property features a full kitchen and living room, finished basement, a large deck, charcoal grill (you supply the charcoal and lighter fluid) and hot tub! Enjoy the spectacular sunsets, hike the woods and relax by the gas fireplace. - Our hot tubs operate year-round - Pets are allowed, but must be preapproved, and there is a separate, nonrefundable pet fee

Guest favorite
A spacious living room features a modern fireplace with a black brick surround. Comfortable seating options include a gray sofa and colorful armchairs. A wooden coffee table sits centrally, while a large television is mounted on the wall. Light filters in through sliding glass doors, enhancing the room's inviting ambiance.
Cottage in Stoddard
4.91 out of 5 average rating, 329 reviews

Stylish 1 bedroom cottage on the Mississippi River

This unique place has a style all its own. Conveniently located by the Mississippi River and highway 35. The place gives you a cabin feel close to La Crosse! 15 minute drive to downtown La Crosse and 3 miles North of Stoddard puts you in a great central location for the area. Mt. La Crosse is super close to enjoy skiing/snowboarding. Goose Island is 5 minutes away. Great spot for bird watching, fishing, kayaking, boat launches, hiking or frisbee golf. Pets are welcome. No cleaning fee!

Top guest favorite
A covered porch features sturdy wooden beams and railings, with two woven chairs adorned with soft cushions. The flooring is dark wood, enhancing the natural ambiance created by surrounding greenery. Soft lights line the porch, providing a warm glow in the evening.
Cabin in Mindoro
5 out of 5 average rating, 135 reviews

Stunning Views! - Krueger Cabin @HighPointRetreats

Perched in the solitude of nature, our ridge top cabin offers a picturesque view at one of the top elevations in all La Crosse County. Cozy up to your loved ones, relax with friends, or find inspiration in this luxury cabin in the woods. Krueger cabin is named after Krueger Summit located just southwest of the cabin. Krueger sleeps four and is non-smoking. Get your front row sunset seats on the private patio and relax by the fire. Immerse yourself in the tranquility and come stay us.

Top guest favorite
The cabin's exterior is showcased against a backdrop of lush trees. A sloped metal roof complements the wooden siding. A welcoming entry is framed by a set of stairs leading to the front porch. Gravel surfaces surround the cabin, enhancing its secluded feel.
Cabin in Eastman
5 out of 5 average rating, 104 reviews

SereniTree Cabin-Modern Rustic Getaway

Modern Rustic Family Getaway- Our cabin is not a place to stay while on vacation...our cabin is the vacation! You can come and enjoy the surrounding areas if you want, but you can also just come and spend the entire time away from the outside world. It is a quiet, peaceful, relaxing place to just unwind. Located up on a bluff, between Prairie Du Chien and Ferryville, this cabin gets you about 5 minutes from the river but allows you the serenity of being tucked away in the trees.

Top guest favorite
The interior of the silo guesthouse features a circular design with wooden beams overhead. A cozy seating area includes a large sectional sofa and a stylish ottoman. Natural light enters through multiple windows, enhancing the space, while a staircase leads to a loft area.
Farm stay in Caledonia
4.99 out of 5 average rating, 108 reviews

Silo Loft Guesthouse

Our silo guesthouse provides a beautiful country retreat surrounded by hundreds of acres of woods and farm land. This working dairy farm is the perfect stay for a tranquil get away or the full dairy farm experience. If you’re looking for a CLEAN, peaceful & unique stay, this is the place for you! Recent guests say it’s the “hidden gem” of MN! Just 10-30 minutes from local coffee shops, restaurants, and many outdoor activities, this getaway has something for everyone!

Top guest favorite
A cabin exterior is showcased, featuring dark wood siding and a steeply pitched roof. A spacious deck with chairs and potted plants invites relaxation. Large windows allow for natural light, and a balcony is visible above the entrance, enhancing the overall charm of the space.
Cabin in Viola
5 out of 5 average rating, 147 reviews

River Valley Cabin

Very private on-the-grid cabin overlooking the Kickapoo River. Kitchen & bath, dining room, one bedroom and futon in the large living room. TV and internet, laundry and cooking. Bring your own phone. Two additional cots provided. Stunning views for every season, a unique and colorful experience in nature any day of the year. The best hunting and fishing, canoeing and horse riding, nature trails, morels and foraging.

Popular amenities for De Soto vacation rentals

  1. Airbnb
  2. United States
  3. Wisconsin
  4. Vernon County
  5. De Soto