
Vacation rentals in Quartiere San Lorenzo, Rome
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Top-rated vacation rentals in Quartiere San Lorenzo, Rome
Guests agree: these stays are highly rated for location, cleanliness, and more.

Lamperini 79 historic palazzo
A quaint apartment in the San Lorenzo district, renovated with due respect for the building's historical/cultural identity, used as the set of Mario Monicelli's film "I Soliti Ignoti" (Big Deal on Madonna Street). Quiet, yet located in a lively neighborhood full of various bars and restaurants, preserving an authentic, non-touristy nature Connections: bus to the historic center (71 and 492) 20m away, tram 3 to Colosseum and Trastevere and tram 19 to San Pietro, 15 min walk from Roma Termini (metro A and B), very close to La Sapienza University
ValueLocationAmenities
4.94 out of 5 average rating, 255 reviews
central cozy & nice apartment, Rome
Relax in this serene and centrally located space. The apartment, quiet and surrounded by restaurants, supermarkets, and services, enjoys a strategic location just a 15-minute walk from Rome Tiburtina station. Excellent connections to the airports are available via trains and buses. The historic city center is just 6 metro stops away. Equipped with *two bathrooms with showers*, air conditioning, ultra-fast Wi-Fi, and a 36-inch TV, the apartment also provides linens and towels for your convenience
ValueLocationSolo travel
4.95 out of 5 average rating, 186 reviews
Charming Cozy Flat in San Lorenzo
Cozy and tastefully renovated flat in the heart of San Lorenzo. Small but very charming, with a fully equipped kitchen and a beautifully redone bathroom. Comfortable and functional, perfect for relaxing after a day in Rome. 15–20 min walk to Termini (direct train to Fiumicino Airport) and 15 min to Metro A (Manzoni) for easy access to the historic center and the Vatican. You can access many parts of the city with the convenient bus 3 just at the doorstep. Perfect for couples or solo travellers!
ValueLocationComfort
5.0 out of 5 average rating, 10 reviews
Super garden terrace in the heart of Rome
Imagine waking up with breakfast in the sun, a sunset aperitif or a moment of pure relaxation on our garden terrace: a cozy oasis where you can recharge and feel right at home. Let yourself be enveloped by the neighborhood’s authentic and youthful energy, with its traditional flavors, characteristic venues, and exciting atmosphere. In the heart of the city, just a 10-minute walk from Termini and 20 minutes from the Colosseum, to experience Rome with the freedom of having it always within reach.
ValueLocationAccess
4.97 out of 5 average rating, 117 reviews
Independent apartment at San Lorenzo
Independent apartment for up to 4 guests in the authentic and vibrant San Lorenzo district, on the ground floor of a historical building. Fully equipped for the most comfortable stay in Rome — like home, but better. Bedroom with king-size memory foam bed and Smart TV, marble bathroom with washer/dryer, all-electric Miele kitchen, living area with sofa bed and second Smart TV. Free streaming apps and high-speed Wi-Fi. Restaurants, wine bars, shops and public transport all at walking distance.
FamilyLocationAccess
5.0 out of 5 average rating, 225 reviews
Oliva | S. Lorenzo Home in Rome!
Are you looking for a stylish, newly renovated, and comfortable apartment with two rooms? You are in the right place! :) my house will be perfect for your stay. Cleanliness for me is a priority, so you will find your new home in Rome spotless and fully furbished with fluffy towels and soft hotel style linen. Fast wifi, A/C, separated and well equipped kitchen to satisfy your culinary caprices. You will stay in San Lorenzo, a neighborhood famous for its vibrant nightlife and easy connections!
LocationValueView
4.89 out of 5 average rating, 107 reviews
"At my parents' house" in the heart of San Lorenzo
In the characteristic neighborhood of San Lorenzo you can stay "A casa dei miei", between tradition and modern comforts. All amenities are within reach. Restaurants, pizzerias, supermarkets, train station and public transport that will take you to the heart of Rome in no time. For example, the trams below the house will take you to the Colosseum, Circus Maximus, Trastevere or Villa Borghese in a short time. Please note: The price includes the tourist tax.
LocationFamilyKitchen
4.95 out of 5 average rating, 63 reviews
Giancarla Luxury Apartment Rome San LorenzoTermini
Elegance and Comfort in the Heart of Rome Experience an unforgettable stay in this refined flat in the heart of Rome. Just 10 minutes' walk from Termini Station and 2 km from the Colosseum and Roman Forum, the location is ideal for exploring the city. From Termini, reach Florence, Naples and the whole of Italy: art, culture and authentic flavours. Elegant, pet-friendly and equipped with every modern comfort. Book now and discover Rome in style!
LocationValueIndoor spaces
5.0 out of 5 average rating, 28 reviews
Apartment in Rome VestiniHouse
Cozy independent apartment with double bedroom that can be converted into two single beds with the possibility of an additional bed for a child or teenager. A kitchen equipped with every comfort: a set of dishes, glasses, pots, kettle, induction hob, refrigerator, microwave, and espresso machine for pleasant relaxation. The accommodation has air conditioning to cool the rooms in summer and heating for winter and fast wifi.
LocationValueLaundry
4.97 out of 5 average rating, 176 reviews
Comfortable loft-style studio apartment in San Lorenzo.
PLEASE READ THE DESCRIPTION IN DETAIL BEFORE BOOKING! Located on the ground floor of a quiet building, inside the condominium courtyard. A unique, comfortable environment with a well-stocked kitchen, a sofa, a smart TV, and ultra-fast WiFi. Spacious bathroom with overhead shower. The sleeping area is upstairs and has the option of either one double bed or two twin beds. Let me know which option you prefer.
ValueFamilyQuiet
4.91 out of 5 average rating, 313 reviews
BoHo Studio & Terrace
Bohemian studio in the heart of San Lorenzo. Bright and quiet environment with all the comforts for travelers. Two bedrooms, a kitchen with a peninsula and a large internal terrace make it the perfect spot to relax and plan your Roman stay. Close to major attractions, the lively San Lorenzo neighborhood is well-connected, near Tiburtina and Termini stations, and rich in typical restaurants and bars.
LocationValueKitchen
5.0 out of 5 average rating, 24 reviews
Tibersail: bright two-room apartment in San Lorenzo
With its newly furnished modern interiors and sunny spaces, TiberSail is a cozy and comfortable starting point to take a look at the most local and authentic side of Rome. The apartment can comfortably accommodate a couple or even a family with children or a small group of friends, with the two additional guests who can comfortably sit in the pull-out sofa bed in the living room.
LocationValueHeating
4.88 out of 5 average rating, 90 reviewsPopular amenities for Quartiere San Lorenzo, Rome vacation rentals
Other great vacation rentals in Quartiere San Lorenzo, Rome

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Cozy Apartment in San Lorenzo
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4.8 out of 5 average rating, 99 reviews
Casa Frugalis - Elegant house near the City Center
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5.0 out of 5 average rating, 41 reviews
Mary's gallery
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4.95 out of 5 average rating, 60 reviews
Cozy Loft San Lorenzo neighbourhood and Termini
LocationAccessQuiet
5.0 out of 5 average rating, 17 reviewsDestinations to explore
- Colosseum
- Trastevere
- Roma Termini
- Trevi Fountain
- Roma Termini
- Pantheon
- Stadio Olimpico
- Piazza Navona
- Campo de' Fiori
- Spanish Steps
- Pigneto
- Lake Bracciano
- Terminillo
- Piazza di Spagna
- Lago del Turano
- Ponte Milvio
- Roma Trastevere
- Vatican Museum
- Sapienza University of Rome
- Villa Borghese
- Roma Tuscolana
- Piazza del Popolo
- Circus Maximus
- Re di Roma





