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Vacation rentals in Quartiere San Lorenzo, Rome

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Top-rated vacation rentals in Quartiere San Lorenzo, Rome

Guests agree: these stays are highly rated for location, cleanliness, and more.

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Guest favorite
A bright and airy bedroom features a spacious bed with neatly arranged white linens and a decorative throw. Natural light filters through a sheer curtain at the window. A small TV and chair enhance the space, while a pendant light provides warmth.
Condo in Rome

Lamperini 79 historic palazzo

A quaint apartment in the San Lorenzo district, renovated with due respect for the building's historical/cultural identity, used as the set of Mario Monicelli's film "I Soliti Ignoti" (Big Deal on Madonna Street). Quiet, yet located in a lively neighborhood full of various bars and restaurants, preserving an authentic, non-touristy nature Connections: bus to the historic center (71 and 492) 20m away, tram 3 to Colosseum and Trastevere and tram 19 to San Pietro, 15 min walk from Roma Termini (metro A and B), very close to La Sapienza University

ValueLocationAmenities

4.94 out of 5 average rating, 255 reviews
Top guest favorite
A cozy living area features a comfortable sofa adorned with patterned cushions. A small table with blue chairs is positioned nearby, complemented by vibrant artwork on the walls. Natural light enters through an open window, creating a welcoming atmosphere.
Condo in Rome

central cozy & nice apartment, Rome

Relax in this serene and centrally located space. The apartment, quiet and surrounded by restaurants, supermarkets, and services, enjoys a strategic location just a 15-minute walk from Rome Tiburtina station. Excellent connections to the airports are available via trains and buses. The historic city center is just 6 metro stops away. Equipped with *two bathrooms with showers*, air conditioning, ultra-fast Wi-Fi, and a 36-inch TV, the apartment also provides linens and towels for your convenience

ValueLocationSolo travel

4.95 out of 5 average rating, 186 reviews
Guest favorite
Apartment in Rome

Charming Cozy Flat in San Lorenzo

Cozy and tastefully renovated flat in the heart of San Lorenzo. Small but very charming, with a fully equipped kitchen and a beautifully redone bathroom. Comfortable and functional, perfect for relaxing after a day in Rome. 15–20 min walk to Termini (direct train to Fiumicino Airport) and 15 min to Metro A (Manzoni) for easy access to the historic center and the Vatican. You can access many parts of the city with the convenient bus 3 just at the doorstep. Perfect for couples or solo travellers!

ValueLocationComfort

5.0 out of 5 average rating, 10 reviews
Top guest favorite
A private garden terrace showcases a mix of colorful chairs and small black tables among flourishing greenery. A shaded area with a slatted roof provides comfort, while a spacious dining table stands ready for gatherings. The tranquil setting invites relaxation and enjoyment.
Condo in Rome

Super garden terrace in the heart of Rome

Imagine waking up with breakfast in the sun, a sunset aperitif or a moment of pure relaxation on our garden terrace: a cozy oasis where you can recharge and feel right at home. Let yourself be enveloped by the neighborhood’s authentic and youthful energy, with its traditional flavors, characteristic venues, and exciting atmosphere. In the heart of the city, just a 10-minute walk from Termini and 20 minutes from the Colosseum, to experience Rome with the freedom of having it always within reach.

ValueLocationAccess

4.97 out of 5 average rating, 117 reviews
Top guest favorite
A spacious living area features a combination of modern and vintage design elements. A comfortable brown sofa and a floral armchair provide seating. A wooden dining table for four stands nearby, while a sleek kitchen is visible in the background with ample cabinetry.
Apartment in Esquilino

Independent apartment at San Lorenzo

Independent apartment for up to 4 guests in the authentic and vibrant San Lorenzo district, on the ground floor of a historical building. Fully equipped for the most comfortable stay in Rome — like home, but better. Bedroom with king-size memory foam bed and Smart TV, marble bathroom with washer/dryer, all-electric Miele kitchen, living area with sofa bed and second Smart TV. Free streaming apps and high-speed Wi-Fi. Restaurants, wine bars, shops and public transport all at walking distance.

FamilyLocationAccess

5.0 out of 5 average rating, 225 reviews
Superhost
A spacious living area features a comfortable sofa bed, adorned with colorful cushions. Above the sofa, two framed artworks display the words 'Roma' and 'viaggiare.' A modern floor lamp stands beside the sofa, providing soft lighting.
Apartment in Rome

Oliva | S. Lorenzo Home in Rome!

Are you looking for a stylish, newly renovated, and comfortable apartment with two rooms? You are in the right place! :) my house will be perfect for your stay. Cleanliness for me is a priority, so you will find your new home in Rome spotless and fully furbished with fluffy towels and soft hotel style linen. Fast wifi, A/C, separated and well equipped kitchen to satisfy your culinary caprices. You will stay in San Lorenzo, a neighborhood famous for its vibrant nightlife and easy connections!

LocationValueView

4.89 out of 5 average rating, 107 reviews
Guest favorite
A cozy living area is presented, featuring a round dining table surrounded by ornate chairs. A vintage wooden sideboard adds character, while a flat-screen TV is positioned nearby. Soft natural light enters through the window, illuminating the warm yellow walls and traditional decor.
Condo in Rome

"At my parents' house" in the heart of San Lorenzo

In the characteristic neighborhood of San Lorenzo you can stay "A casa dei miei", between tradition and modern comforts. All amenities are within reach. Restaurants, pizzerias, supermarkets, train station and public transport that will take you to the heart of Rome in no time. For example, the trams below the house will take you to the Colosseum, Circus Maximus, Trastevere or Villa Borghese in a short time. Please note: The price includes the tourist tax.

LocationFamilyKitchen

4.95 out of 5 average rating, 63 reviews
Top guest favorite
Apartment in Rome

Giancarla Luxury Apartment Rome San LorenzoTermini

Elegance and Comfort in the Heart of Rome Experience an unforgettable stay in this refined flat in the heart of Rome. Just 10 minutes' walk from Termini Station and 2 km from the Colosseum and Roman Forum, the location is ideal for exploring the city. From Termini, reach Florence, Naples and the whole of Italy: art, culture and authentic flavours. Elegant, pet-friendly and equipped with every modern comfort. Book now and discover Rome in style!

LocationValueIndoor spaces

5.0 out of 5 average rating, 28 reviews
Guest favorite
Condo in Rome

Apartment in Rome VestiniHouse

Cozy independent apartment with double bedroom that can be converted into two single beds with the possibility of an additional bed for a child or teenager. A kitchen equipped with every comfort: a set of dishes, glasses, pots, kettle, induction hob, refrigerator, microwave, and espresso machine for pleasant relaxation. The accommodation has air conditioning to cool the rooms in summer and heating for winter and fast wifi.

LocationValueLaundry

4.97 out of 5 average rating, 176 reviews
Guest favorite
Condo in Rome

Comfortable loft-style studio apartment in San Lorenzo.

PLEASE READ THE DESCRIPTION IN DETAIL BEFORE BOOKING! Located on the ground floor of a quiet building, inside the condominium courtyard. A unique, comfortable environment with a well-stocked kitchen, a sofa, a smart TV, and ultra-fast WiFi. Spacious bathroom with overhead shower. The sleeping area is upstairs and has the option of either one double bed or two twin beds. Let me know which option you prefer.

ValueFamilyQuiet

4.91 out of 5 average rating, 313 reviews
Top guest favorite
A bright studio space features a spacious bed with light bedding and decorative pillows. A vintage-style wardrobe and a comfortable armchair are visible, alongside a patterned sofa. Large windows draped with soft curtains allow ample natural light to fill the room.
Apartment in Rome

BoHo Studio & Terrace

Bohemian studio in the heart of San Lorenzo. Bright and quiet environment with all the comforts for travelers. Two bedrooms, a kitchen with a peninsula and a large internal terrace make it the perfect spot to relax and plan your Roman stay. Close to major attractions, the lively San Lorenzo neighborhood is well-connected, near Tiburtina and Termini stations, and rich in typical restaurants and bars.

LocationValueKitchen

5.0 out of 5 average rating, 24 reviews
Superhost
A dining area features a wooden table set for four, with white plates and glasses arranged neatly. Yellow chairs surround the table, providing a cheerful contrast. A modern flat-screen TV is mounted on the wall nearby. Natural light softens the warm tones of the wooden flooring.
Condo in Rome

Tibersail: bright two-room apartment in San Lorenzo

With its newly furnished modern interiors and sunny spaces, TiberSail is a cozy and comfortable starting point to take a look at the most local and authentic side of Rome. The apartment can comfortably accommodate a couple or even a family with children or a small group of friends, with the two additional guests who can comfortably sit in the pull-out sofa bed in the living room.

LocationValueHeating

4.88 out of 5 average rating, 90 reviews

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