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Vacation rentals in Quartiere San Lorenzo, Rome

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Top-rated vacation rentals in Quartiere San Lorenzo, Rome

Guests agree: these stays are highly rated for location, cleanliness, and more.

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Guest favorite
A bright and airy bedroom features a spacious bed with neatly arranged white linens and a decorative throw. Natural light filters through a sheer curtain at the window. A small TV and chair enhance the space, while a pendant light provides warmth.
Condo in Rome

Lamperini 79 historic palazzo

A quaint apartment in the San Lorenzo district, renovated with due respect for the building's historical/cultural identity, used as the set of Mario Monicelli's film "I Soliti Ignoti" (Big Deal on Madonna Street). Quiet, yet located in a lively neighborhood full of various bars and restaurants, preserving an authentic, non-touristy nature Connections: bus to the historic center (71 and 492) 20m away, tram 3 to Colosseum and Trastevere and tram 19 to San Pietro, 15 min walk from Roma Termini (metro A and B), very close to La Sapienza University

4.94 out of 5 average rating, 255 reviews
Top guest favorite
A cozy living area features a comfortable sofa adorned with patterned cushions. A small table with blue chairs is positioned nearby, complemented by vibrant artwork on the walls. Natural light enters through an open window, creating a welcoming atmosphere.
Condo in Rome

central cozy & nice apartment, Rome

Relax in this serene and centrally located space. The apartment, quiet and surrounded by restaurants, supermarkets, and services, enjoys a strategic location just a 15-minute walk from Rome Tiburtina station. Excellent connections to the airports are available via trains and buses. The historic city center is just 6 metro stops away. Equipped with *two bathrooms with showers*, air conditioning, ultra-fast Wi-Fi, and a 36-inch TV, the apartment also provides linens and towels for your convenience

4.95 out of 5 average rating, 186 reviews
Guest favorite
Apartment in Rome

Charming Cozy Flat in San Lorenzo

Cozy and tastefully renovated flat in the heart of San Lorenzo. Small but very charming, with a fully equipped kitchen and a beautifully redone bathroom. Comfortable and functional, perfect for relaxing after a day in Rome. 15–20 min walk to Termini (direct train to Fiumicino Airport) and 15 min to Metro A (Manzoni) for easy access to the historic center and the Vatican. You can access many parts of the city with the convenient bus 3 just at the doorstep. Perfect for couples or solo travellers!

5.0 out of 5 average rating, 12 reviews
Top guest favorite
A private garden terrace showcases a mix of colorful chairs and small black tables among flourishing greenery. A shaded area with a slatted roof provides comfort, while a spacious dining table stands ready for gatherings. The tranquil setting invites relaxation and enjoyment.
Condo in Rome

Super garden terrace in the heart of Rome

Imagine waking up with breakfast in the sun, a sunset aperitif or a moment of pure relaxation on our garden terrace: a cozy oasis where you can recharge and feel right at home. Let yourself be enveloped by the neighborhood’s authentic and youthful energy, with its traditional flavors, characteristic venues, and exciting atmosphere. In the heart of the city, just a 10-minute walk from Termini and 20 minutes from the Colosseum, to experience Rome with the freedom of having it always within reach.

4.97 out of 5 average rating, 117 reviews
Guest favorite
The living/dining room features a round wooden table set for four guests beneath a pendant light. A cozy sofa accompanies the dining area. Natural light filters through the large window, illuminating the room's vaulted antique ceiling and parquet flooring.
Condo in Rome

Campani Comfort

A newly renovated 1 bedroom apartment in the well-known San Lorenzo area, close to Termini train station. The apartment is on a quiet street, but the neighborhood buzzes with artisan shops, a lively nightlife, and many restaurants. Sleeps up to 4. New air-conditioning and heating systems. Bedroom with double bed, antique furniture and a walk-in closet Fully equipped kitchen Vaulted antique ceilings Living/dining room with comfortable sofa-bed Fast Wifi. Easy access to FAO and Rome center.

4.93 out of 5 average rating, 44 reviews
Top guest favorite
A spacious living area features a combination of modern and vintage design elements. A comfortable brown sofa and a floral armchair provide seating. A wooden dining table for four stands nearby, while a sleek kitchen is visible in the background with ample cabinetry.
Apartment in Esquilino

Independent apartment at San Lorenzo

Independent apartment for up to 4 guests in the authentic and vibrant San Lorenzo district, on the ground floor of a historical building. Fully equipped for the most comfortable stay in Rome — like home, but better. Bedroom with king-size memory foam bed and Smart TV, marble bathroom with washer/dryer, all-electric Miele kitchen, living area with sofa bed and second Smart TV. Free streaming apps and high-speed Wi-Fi. Restaurants, wine bars, shops and public transport all at walking distance.

5.0 out of 5 average rating, 226 reviews
Superhost
An open loft layout is depicted, featuring rustic wooden beams overhead. A compact dining area is visible with a round table and four upholstered chairs. A comfortable sofa sits nearby, with a lofted bed accessed by a staircase. Large windows allow natural light to enhance the space.
Condo in Rome

Pretty Loft San Lorenzo Rome (Termini)

Lovely bright and characteristic LOFT. Strategically located with respect to the main stations (Termini and Tiburtina), it is connected by metro, streetcar and bus. Located in a characteristic neighborhood, it is ideal for those who want to find every kind of comfort during the day (supermarket, pharmacy, laundry...), and in the evening relax in the many bars and restaurants. Not only suitable for tourists, but also for professionals given the proximity to the University, Polyclinic, CNR.

4.87 out of 5 average rating, 218 reviews
Guest favorite
A cozy living area is presented, featuring a round dining table surrounded by ornate chairs. A vintage wooden sideboard adds character, while a flat-screen TV is positioned nearby. Soft natural light enters through the window, illuminating the warm yellow walls and traditional decor.
Condo in Rome

"At my parents' house" in the heart of San Lorenzo

In the characteristic neighborhood of San Lorenzo you can stay "A casa dei miei", between tradition and modern comforts. All amenities are within reach. Restaurants, pizzerias, supermarkets, train station and public transport that will take you to the heart of Rome in no time. For example, the trams below the house will take you to the Colosseum, Circus Maximus, Trastevere or Villa Borghese in a short time. Please note: The price includes the tourist tax.

4.94 out of 5 average rating, 64 reviews
Guest favorite
The living area features a light wood ceiling with exposed beams, creating an airy feel. A spacious sofa faces a wall-mounted smart TV. A dining table is set with plates and glasses. Large windows allow natural light, complemented by indoor plants for a refreshing touch.
Apartment in Rome

Oasi Piceni Apartment San Lorenzo

Oasi Piceni is the ideal place for those who want to live an authentic experience in the Eternal City. Located in the heart of San Lorenzo, a neighborhood rich in history, art and culture, perfectly connected to all places of interest. The apartment is spacious and equipped with all the necessary amenities for a pleasant stay. It has two double bedrooms, a living room with sofa, a fully equipped kitchen and a private terrace.

4.94 out of 5 average rating, 121 reviews
Guest favorite
Condo in Rome

Apartment in Rome VestiniHouse

Cozy independent apartment with double bedroom that can be converted into two single beds with the possibility of an additional bed for a child or teenager. A kitchen equipped with every comfort: a set of dishes, glasses, pots, kettle, induction hob, refrigerator, microwave, and espresso machine for pleasant relaxation. The accommodation has air conditioning to cool the rooms in summer and heating for winter and fast wifi.

4.97 out of 5 average rating, 176 reviews
Top guest favorite
A bright studio space features a spacious bed with light bedding and decorative pillows. A vintage-style wardrobe and a comfortable armchair are visible, alongside a patterned sofa. Large windows draped with soft curtains allow ample natural light to fill the room.
Apartment in Rome

BoHo Studio & Terrace

Bohemian studio in the heart of San Lorenzo. Bright and quiet environment with all the comforts for travelers. Two bedrooms, a kitchen with a peninsula and a large internal terrace make it the perfect spot to relax and plan your Roman stay. Close to major attractions, the lively San Lorenzo neighborhood is well-connected, near Tiburtina and Termini stations, and rich in typical restaurants and bars.

5.0 out of 5 average rating, 24 reviews
Superhost
A dining area features a wooden table set for four, with white plates and glasses arranged neatly. Yellow chairs surround the table, providing a cheerful contrast. A modern flat-screen TV is mounted on the wall nearby. Natural light softens the warm tones of the wooden flooring.
Condo in Rome

Tibersail: bright two-room apartment in San Lorenzo

With its newly furnished modern interiors and sunny spaces, TiberSail is a cozy and comfortable starting point to take a look at the most local and authentic side of Rome. The apartment can comfortably accommodate a couple or even a family with children or a small group of friends, with the two additional guests who can comfortably sit in the pull-out sofa bed in the living room.

4.88 out of 5 average rating, 90 reviews

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