Vacation rentals in Quartiere San Lorenzo, Rome

A bright and airy bedroom features a spacious bed with neatly arranged white linens and a decorative throw. Natural light filters through a sheer curtain at the window. A small TV and chair enhance the space, while a pendant light provides warmth.

4.94 out of 5 average rating, 255 reviews

Lamperini 79 historic palazzo

A quaint apartment in the San Lorenzo district, renovated with due respect for the building's historical/cultural identity, used as the set of Mario Monicelli's film "I Soliti Ignoti" (Big Deal on Madonna Street). Quiet, yet located in a lively neighborhood full of various bars and restaurants, preserving an authentic, non-touristy nature Connections: bus to the historic center (71 and 492) 20m away, tram 3 to Colosseum and Trastevere and tram 19 to San Pietro, 15 min walk from Roma Termini (metro A and B), very close to La Sapienza University

A cozy living area features a comfortable sofa adorned with patterned cushions. A small table with blue chairs is positioned nearby, complemented by vibrant artwork on the walls. Natural light enters through an open window, creating a welcoming atmosphere.

4.95 out of 5 average rating, 186 reviews

central cozy & nice apartment, Rome

Relax in this serene and centrally located space. The apartment, quiet and surrounded by restaurants, supermarkets, and services, enjoys a strategic location just a 15-minute walk from Rome Tiburtina station. Excellent connections to the airports are available via trains and buses. The historic city center is just 6 metro stops away. Equipped with *two bathrooms with showers*, air conditioning, ultra-fast Wi-Fi, and a 36-inch TV, the apartment also provides linens and towels for your convenience

5.0 out of 5 average rating, 10 reviews

Charming Cozy Flat in San Lorenzo

Cozy and tastefully renovated flat in the heart of San Lorenzo. Small but very charming, with a fully equipped kitchen and a beautifully redone bathroom. Comfortable and functional, perfect for relaxing after a day in Rome. 15–20 min walk to Termini (direct train to Fiumicino Airport) and 15 min to Metro A (Manzoni) for easy access to the historic center and the Vatican. You can access many parts of the city with the convenient bus 3 just at the doorstep. Perfect for couples or solo travellers!

5.0 out of 5 average rating, 226 reviews

A spacious living area features a combination of modern and vintage design elements. A comfortable brown sofa and a floral armchair provide seating. A wooden dining table for four stands nearby, while a sleek kitchen is visible in the background with ample cabinetry.

Apartment in Esquilino

Independent apartment at San Lorenzo

Independent apartment for up to 4 guests in the authentic and vibrant San Lorenzo district, on the ground floor of a historical building. Fully equipped for the most comfortable stay in Rome — like home, but better. Bedroom with king-size memory foam bed and Smart TV, marble bathroom with washer/dryer, all-electric Miele kitchen, living area with sofa bed and second Smart TV. Free streaming apps and high-speed Wi-Fi. Restaurants, wine bars, shops and public transport all at walking distance.

A cozy living area is presented, featuring a round dining table surrounded by ornate chairs. A vintage wooden sideboard adds character, while a flat-screen TV is positioned nearby. Soft natural light enters through the window, illuminating the warm yellow walls and traditional decor.

4.94 out of 5 average rating, 64 reviews

"At my parents' house" in the heart of San Lorenzo

In the characteristic neighborhood of San Lorenzo you can stay "A casa dei miei", between tradition and modern comforts. All amenities are within reach. Restaurants, pizzerias, supermarkets, train station and public transport that will take you to the heart of Rome in no time. For example, the trams below the house will take you to the Colosseum, Circus Maximus, Trastevere or Villa Borghese in a short time. Please note: The price includes the tourist tax.

5.0 out of 5 average rating, 28 reviews

Giancarla Luxury Apartment Rome San LorenzoTermini

Elegance and Comfort in the Heart of Rome Experience an unforgettable stay in this refined flat in the heart of Rome. Just 10 minutes' walk from Termini Station and 2 km from the Colosseum and Roman Forum, the location is ideal for exploring the city. From Termini, reach Florence, Naples and the whole of Italy: art, culture and authentic flavours. Elegant, pet-friendly and equipped with every modern comfort. Book now and discover Rome in style!

Superhost

Loft in Rome

Cozy studio near Termini station A/C

Cozy, charming studio in San Lorenzo. Discover this cozy studio in the vibrant San Lorenzo neighborhood, minutes from the Roma Termini station. Thoughtfully designed, it features an equipped kitchenette area and an elegant full bathroom with vintage-style details. Experience Rome's authentic atmosphere in total tranquility and comfort. Ideal for couples or solo travelers seeking a unique and well-connected space. Your perfect retreat!

5.0 out of 5 average rating, 3 reviews

The living area features a light wood ceiling with exposed beams, creating an airy feel. A spacious sofa faces a wall-mounted smart TV. A dining table is set with plates and glasses. Large windows allow natural light, complemented by indoor plants for a refreshing touch.

4.94 out of 5 average rating, 121 reviews

Oasi Piceni Apartment San Lorenzo

Oasi Piceni is the ideal place for those who want to live an authentic experience in the Eternal City. Located in the heart of San Lorenzo, a neighborhood rich in history, art and culture, perfectly connected to all places of interest. The apartment is spacious and equipped with all the necessary amenities for a pleasant stay. It has two double bedrooms, a living room with sofa, a fully equipped kitchen and a private terrace.

4.97 out of 5 average rating, 176 reviews

Apartment in Rome VestiniHouse

Cozy independent apartment with double bedroom that can be converted into two single beds with the possibility of an additional bed for a child or teenager. A kitchen equipped with every comfort: a set of dishes, glasses, pots, kettle, induction hob, refrigerator, microwave, and espresso machine for pleasant relaxation. The accommodation has air conditioning to cool the rooms in summer and heating for winter and fast wifi.

4.91 out of 5 average rating, 313 reviews

Comfortable loft-style studio apartment in San Lorenzo.

PLEASE READ THE DESCRIPTION IN DETAIL BEFORE BOOKING! Located on the ground floor of a quiet building, inside the condominium courtyard. A unique, comfortable environment with a well-stocked kitchen, a sofa, a smart TV, and ultra-fast WiFi. Spacious bathroom with overhead shower. The sleeping area is upstairs and has the option of either one double bed or two twin beds. Let me know which option you prefer.

A bright studio space features a spacious bed with light bedding and decorative pillows. A vintage-style wardrobe and a comfortable armchair are visible, alongside a patterned sofa. Large windows draped with soft curtains allow ample natural light to fill the room.

5.0 out of 5 average rating, 24 reviews

BoHo Studio & Terrace

Bohemian studio in the heart of San Lorenzo. Bright and quiet environment with all the comforts for travelers. Two bedrooms, a kitchen with a peninsula and a large internal terrace make it the perfect spot to relax and plan your Roman stay. Close to major attractions, the lively San Lorenzo neighborhood is well-connected, near Tiburtina and Termini stations, and rich in typical restaurants and bars.

Superhost

A dining area features a wooden table set for four, with white plates and glasses arranged neatly. Yellow chairs surround the table, providing a cheerful contrast. A modern flat-screen TV is mounted on the wall nearby. Natural light softens the warm tones of the wooden flooring.