Vacation rentals in Prairie du Chien

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Top-rated vacation rentals in Prairie du Chien

Guests agree: these stays are highly rated for location, cleanliness, and more.

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Top guest favorite
The A-frame cabin is nestled among lush greenery, showcasing a wooden exterior and an inviting deck. A winding driveway leads up to the entrance, framed by trees. Flower boxes adorn the front windows, enhancing the cabin's natural surroundings.
Cabin in Eastman
4.97 out of 5 average rating, 140 reviews

TranquiliTree Cabin- Secluded and Relaxing

Are you looking for a cozy, and quiet get-away spot to rest & relax? Our little Tree house Cabin is the perfect spot! Located between Prairie Du Chien, WI and Ferryville, WI- this little A-frame cabin gets you within 5 min. from the river, but allows you to be tucked in a quiet wooded area. It is 900 sq. ft of pure relaxation & nature! Enjoy your morning coffee in the outdoor room or relax nightly by the fire pit. Disconnect 2 Reconnect. TranquiliTree Cabin is a great place to escape and unwind.

Top guest favorite
A cozy sleeping area features a queen bed with a brown coverlet and contrasting pillows. A small dining table with two chairs is positioned nearby. Natural light enters through a window adorned with curtains, while exposed brick adds character to the room.
Apartment in McGregor
4.96 out of 5 average rating, 306 reviews

Cave Courtyard Guest Studio

The Cave Courtyard Guest Studio. A relaxing getaway located on the ground floor of an 1848 historic building just 1 block from the Mississippi River and unique shops and eateries. Sleeps 4 with a queen bed and daybed with pull out trundle, private entrance, private bath with shower, kitchenette with microwave and mini fridge, internet, cable tv and air-conditioning. There is also a private courtyard located below unique cliff side caves. Some food items are also supplied. Adults only-no pets.

Top guest favorite
The Victorian home features a charming architectural design with a turret and expansive wrap-around porch. Large windows are adorned with decorative trim and flower boxes, surrounded by neatly landscaped gardens and lush greenery.
Home in McGregor
4.94 out of 5 average rating, 209 reviews

McGregor Manor Victorian Getaway

Welcome to our beautiful Victorian home located in the quaint town of McGregor, Iowa. Our 2,800 sq. ft. home was built during McGregor's early years as a Mississippi River boom town. Attractions include antiquing, biking, fishing, hunting, hiking and boating! We're a short drive from Pike's Peak, Effigy Mounds and Prairie du Chien. All four bedrooms include a private bath, providing comfort and privacy for each member of your group. Fully furnished and decorated. See below for more details.

Guest favorite
A welcoming exterior of a single-story house is showcased, featuring a subtle brick facade and a gabled roof. An American flag is prominently displayed at the entrance. Lush greenery surrounds the steps leading to the front door, providing a well-maintained appearance.
Home in Prairie du Chien
4.93 out of 5 average rating, 165 reviews

The Bunk House

Book your stay with The Bunk House! Great for large groups, cozy weekends or family getaways. Features include free WiFi, TV/DVD player/DVDs and board games available, fully furnished kitchen, bathrooms, extra makeup stations and free laundry. The Bunk House is conveniently located within walking distance of beautiful downtown Prairie Du Chien~Great bars, restaurants, shopping, farmers/flea markets, water fun, historical sites and so much more. I’d love to help make your stay a memorable one!

Guest favorite
A quaint blue house is shown from the side, surrounded by lush green grass. A wooden fence partially outlines the property, with a few flowering plants positioned along the edge. Clear skies and sunlight illuminate the exterior, highlighting its welcoming presence.
Home in Prairie du Chien
4.98 out of 5 average rating, 151 reviews

Ohio Street Retreat- hot tub, massage chair, pool

After a fun day in The Driftless Area, come relax and unwind in Prairie du Chien. Beautifully decorated 2 bedroom home with a spacious kitchen, large island, dishwasher, washer/dryer & 5' walk in shower. We supply all cooking/baking items/utensils so all you need are your food, drinks and ingredients. Full high-speed internet with smart TVs in both bedrooms and living room. Outdoor pool (seasonal), hot tub and massage chair. We love dogs too, so we provide a dog run (there is a pet fee).

Top guest favorite
A lush green landscape rises just beyond a calm river, with a small collection of buildings visible along the shore. The architecture varies, featuring both traditional and modern designs, under a sky filled with fluffy clouds.
Apartment in Clayton
4.93 out of 5 average rating, 164 reviews

Cozy Apartment Steps from the Mighty Mississippi

Disconnect from the daily grind and enjoy a getaway in this welcoming one bedroom apartment, steps away from the Mighty Mississippi. Located in Clayton, Iowa, Located within walking distance of two delicious restaurants and a boat launch., and only 1/2 hour from the Casino Queen, local wineries, Pikes Peak State Park, as well as the historic communities of Elkader, IA and Prairie Du Chien, WI. Need more space? I also offer a two bedroom apartment: www. airbnb. com/rooms/43979345

Top guest favorite
The two-story home is positioned beside a quiet road, featuring a light-colored exterior with a sloped roof. A spacious garage is integrated into the design, and an American flag is displayed on a nearby building. Lush greenery surrounds the property.
Home in Waterville
4.87 out of 5 average rating, 118 reviews

Paint Creek Place

Stay next to beautiful Paint Creek in the heart of Iowa's Driftless Region. Guests can choose from a queen bed or double futon upstairs in the main living area. We also have a queen air mattress available. Enjoy the scenic view of one of Iowa's best trout streams from the house or adjacent green space. Take a 5 minute drive to Yellow River State Forest, and enjoy close access to other public hunting and fishing areas, Effigy Mounds, Pike's Peak, and the Mississippi River.

Top guest favorite
A serene view of the Mighty Mississippi River is captured during sunset. Soft hues of orange and purple fill the sky, while the landscape is framed by lush green trees and gentle mists rising from the water, creating a tranquil atmosphere.
Home in Lynxville
4.85 out of 5 average rating, 248 reviews

Highland Hideaway

A cozy, secluded two bedroom cabin located in the driftless region with incredible views of the Mighty Mississippi!!! If your looking for peace, quiet, and beautiful sunsets this is your place. Only 20 minutes from Wyalusing state park, The Effigy Mounds (sacred Indian Burial Grounds) Pikes Peak and Historic Villa Louis. This beautiful cabin centers you 30 miles from amazing hiking, fishing, hunting and nature for a weekend of disconnecting from busy life.

Guest favorite
A modern cabin is seen elevated above the water, featuring large decks that offer river views. A private boat dock is visible next to the cabin, surrounded by greenery and a sandy shore. The calm river reflects the blue sky, enhancing the peaceful setting.
Cottage in Prairie du Chien
4.82 out of 5 average rating, 119 reviews

Gorgeous River Getaway

Modern Private cabin with one of a kind bluff and river views will amaze all. The quiet tranquility of the Mississippi River will allow you to disconnect from everyday worries. Open floor plan with two large decks will allow your enjoyment of sunrises while enjoying your morning coffee or the sunsets as you unwind from your days adventures in area. Property is a short drive to Yellow River Forest, Pikes Peak, Effigy Mounds, and Spook Cave.

Top guest favorite
The vibrant red home features multiple large windows, allowing natural light to enhance the interior spaces. A spacious deck extends from the house, bordered by trees and rocky terrain, creating a picturesque setting amidst the lush surroundings.
Home in McGregor
5 out of 5 average rating, 99 reviews

#StayBluffside: Mississippi River Oasis-> McGregor

The Bluffside Retreat is an ideal location for the adventure seekers who want a unique and private experience that is still close to all the action. The home is situated alongside the bluff on a private & partially wooded lot within walking distance of the Mississippi River, historic downtown McGregor and a Pikes Peak State Park TrailHead. It is a charming “home away from home” that has all the amenities for a memorable vacation stay.

Superhost
A log cabin features a warm wooden exterior with a pitched roof. Large windows provide light to the interior, framed by natural stone landscaping. The surrounding grassy area is bordered by trees, enhancing the cabin's natural setting.
Cabin in Harpers Ferry
4.84 out of 5 average rating, 248 reviews

Andy Mountain Cabin #2

Whether you are….. Camping, Gathering with family or friends, Hunting the Yellow River State Forest, Fishing and Boating on the Mississippi River or Snowmobiling ……Andy Mountain Cabins is the perfect Home Base for intimate or large groups. Andy Mountain Cabins, LLC is the prime log cabin choice for lodging or motels in Northeast Iowa, Allamakee County, Harpers Ferry Ia, Prairie du Chien WI or McGregor Iowa.

Top guest favorite
The exterior of the 1884 Red Brick Cottage is shown, featuring a classic brick facade and a welcoming front porch with a screened area. Lush green lawns surround the property, with a driveway leading to the house. Scenic hills are visible in the background.
Home in Marquette
4.96 out of 5 average rating, 198 reviews

1884 Red Brick Cottage

Step back in time to a quiet small town in Iowa, nestled within the hills of the driftless area. Time seems to stand still while you're here. The 1884 Red Brick Cottage offers 3+ Bedrooms in a peaceful neighborhood, close to riverfront activities, casino and downtown Marquette. Spacious backyard and sideyard, house is fully furnished and includes a firepit and gas grill for evening outdoor activities.

Popular amenities for Prairie du Chien places to stay

When is the best time to visit Prairie du Chien?

MonthJanFebMarAprMayJunJulAugSepOctNovDec
Avg. priceG$20,293 GYDG$17,783 GYDG$22,176 GYDG$20,712 GYDG$25,733 GYDG$32,637 GYDG$29,290 GYDG$29,499 GYDG$29,917 GYDG$27,197 GYDG$24,896 GYDG$22,595 GYD
Avg. temp-7°C-5°C2°C9°C15°C20°C22°C21°C17°C10°C2°C-4°C

Frequently Asked Questions

  • How much does it cost to stay in house rentals in Prairie du Chien?

    Experience the best of Prairie du Chien with our house rentals, starting at about $90 per day, before taxes and fees. Embrace comfort and style while staying within your budget in your home away from home.

  • Are there vacation rentals with a dedicated workspace in Prairie du Chien?

    Yes! Work meets play with ease at over 10 vacation rentals in Prairie du Chien featuring dedicated workspaces. Stay connected and productive in your home away from home.

  • Do house rentals in Prairie du Chien have wifi?

    Absolutely! We offer over 10 house rentals with wifi in Prairie du Chien. Enjoy a tailored experience with all the comforts you desire.

  • Are there family-friendly house rentals in Prairie du Chien?

    Prairie du Chien has more than 10 family-friendly house rentals. Amenities on the property may include high chairs, travel cribs, or strollers.

  • Do house rentals in Prairie du Chien have air conditioning?

    Absolutely! We offer over 10 house rentals with air conditioning in Prairie du Chien. Enjoy a tailored experience with all the comforts you desire.

  • What are the most popular amenities for House Rentals in Prairie du Chien?

    Enhance your stay in our House Rentals with the most popular amenities: over 10 homes with wifi, over 10 homes with air conditioning, and more. Indulge in the ultimate retreat, tailored to your preferences.

Quick stats about vacation rentals in Prairie du Chien

  • Total vacation rentals

    Explore 30 vacation rentals in Prairie du Chien

  • Nightly prices starting at

    Prairie du Chien vacation rentals start at G$10,461 GYD per night before taxes and fees

  • Verified guest reviews

    Over 1,550 verified reviews to help you choose

  • Family-friendly vacation rentals

    20 properties offer extra space & kid-friendly amenities

  • Pet-friendly vacation rentals

    Find 10 rentals that welcome pets

  • Rentals with dedicated workspaces

    10 properties have a dedicated workspace

  • Wi-Fi availability

    30 of Prairie du Chien vacation rentals include wi-fi access

  • Popular amenities for guests

    Guests love Gym, BBQ grill, and Laptop-friendly workspace across Prairie du Chien rentals

  • 4.8 Average rating

    Prairie du Chien stays are highly rated by guests—averaging 4.8 out of 5!