
Guesthouse vacation rentals in Pima County
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Top-rated guesthouse rentals in Pima County
Guests agree: these guesthouse rentals are highly rated for location, cleanliness, and more.

Studio in the Saguaro Forest
New modern studio guesthouse on 3.2 lush acres secluded at the edge of the Saguaro National Park! Cleaning fees included in nightly rate. Private indoor/outdoor living areas. 8 miles easy access to downtown, 9 miles to the Desert Museum. High speed Starlink WiFi, Tuft & Needle queen bed, washer/dryer combo, 4k smart TV, whisper quiet mini split, full size sleeper sofa for 3rd guest. Nice retreat from midtown traffic. Check out my other similar listing on the property. LICENSE: 21465687

Time Capsule in the Sonoran Desert
Time Capsule is a unique experience in an space age module dropped in the middle of an 11 acres desert sanctuary and sculpture park, adjacent to the Saguaro National Park. Enjoy the quietness of the desert in a safe environment located at just 35 minutes from downtown Tucson. Because of the refinement of the interior design we cannot accept any pet, service animal, nor children in the Time Capsule. Please note that check in is in person only and not later than 10:00PM. No exception!

Newly Constructed Downtown Guesthouse
This newly constructed, spacious guest house has an open floor plan with a loft bedroom featuring the most cozy queen-sized bed. The bathroom has a soaking tub and there’s an outdoor shower too. There’s a large gated yard and three porches on which to enjoy a morning cup of coffee or tea. Located in the coveted Dunbar Spring neighborhood, the home is walking distance to the University of Arizona, 4th Ave, downtown, lots of coffee shops and restaurants and the Warehouse Arts District.

The Southwest Knest
Cozy and charming, this private guest house sits in the heart of Tucson and makes a perfect home base during your visit to the Southwest! Studio layout is spacious and relaxing for 2. Fully equipped kitchen, bathroom with walk-in shower, Ghostbed mattress, and comfortable work space/fast wifi for those of you working remotely. Easy access to airport, U of A, Saguaro NP, shopping, and hiking trails. Coded entry makes it a breeze to come and go, no shared keys. Come rest at the Knest!

Attractive Casita In Tucson
A charming getaway casita with stunning views of the majestic Saguaro National Park and the Picture Rock Mountains for spectacular sunsets. The 5-acre site is home to many varieties of cacti, including giant saguaros and other native plants and trees. Through the casita's panoramic windows, you can observe desert vegetation, birds, rabbits, coyotes, bobcats, javelinas, and deer. An evening bath in the jacuzzi under the starry sky will certainly remain in your memory for a long time.

Modern 1 bdrm Casita in Central Broadmoor Village
Start your mornings on the front porch with hummingbirds dancing through the garden, or unwind out back beneath the shade of a palo verde tree. Inside, enjoy the airy, sun-filled vibe of a modern casita with warm southwestern farmhouse style. Just a 10 min walk along the nearby bike path brings you to local favorites like Barrio Bread, and several restaurants. Located in a quiet, central Tucson neighborhood, only 5 mins from the University of Arizona and 5–10 mins from downtown.

Central and Stylish Midcentury Pool House
Our beautiful adobe pool house is a Tucson gem. Comfortable queen bed, fireplace, and stylish modern furnishings with large windows looking out to trees and sparkling pool. Vaulted ceilings and natural light make for a restful space. Located in historic Jefferson Park, it’s a midtown oasis close to the UofA and two blocks from the UMC/Banner Medical Center. Midtown/University location allows for convenient access to all of Tucson. *Newly improved high speed WiFi 11/1/2021

Tucson Poet's Studio
Tucson Poet's Studio was featured in Architectural Digest (10-1-2025) “50 Best Airbnbs Across the United States", New York Magazine (6-19-2015) “Taste the Flavors of Tucson” and LivAbility (7-6-2018) “Accessible Airbnb” *NEW* EV Charger! The studio shares the private, walled courtyard and pool with the main house where my husband and I live. Located in the Peter Howell neighborhood, a convenient midtown area close to everything (2.5 mi to UA, 5 mi to downtown).

Central Casita Minutes from UA & Downtown
Perfect for a weekend getaway or a long-term stay, our casita in midtown is fully equipped with everything you need to experience all that Tucson has to offer. 344 sq ft, this small and mighty space offers a fully-equipped kitchenette, theater-quality entertainment center, high speed wifi access, and washer and dryer access. Enjoy the spacious patio while you sip morning coffee or grill in the evening. You may find it hard to check-out of this cozy gem!

Saguaro Oasis Retreat near National Park
If you love nature this casita is just for you. Located 15 minutes from downtown and only a few minutes from stunning hiking and mountain biking trails in the National Park. The property is very much like a botanical garden with fruit trees filling up the back and a wide variety of succulents filling the front. The casita has its own private porch while the property shares two large communal patios with outdoor dining and a fire pit.

Tiny House in Central Tucson
A great location in central Tucson in an artists sculpture garden. Private and quiet, in a friendly Enclave. Bathroom is shared, and 2 outdoor kitchens are shared. Patio dining areas available, completely furnished, Wifi, microwave, fridge, appliances, and close to coffee shop, restaurants, three major hospitals, and the University. Sorry, but it's not available for couples. Please introduce yourself - thanks much!

🌵 Central Desert Oasis 3 🌵
Enjoy a stylish experience at this centrally located studio. 🚗 Free, private, secure parking 🧹 We do the cleaning - just lock up ☕️ All the caffeine you'll ever need 🚶🏼♀️Walking distance to 4th Ave (8mins) 🚶🏼Walking distance to University (6 mins) The Pie Allen neighborhood is ranked as the 3rd safest neighborhood in Tucson with a walk score of 85/100 on walkscore! Can’t wait to see you!
Popular amenities for Pima County guesthouse rentals
Family-friendly guest house rentals

Cozy midtown guesthouse

Charming Private Oasis Casita with Pool & Hot Tub

Oasis: Casita Colibrí - Little Hummingbird House

Eco-Chic Studio Casita | Near UA, 4th & Dog Park

Cozy Desert Foothills Getaway

Historic University area Downtown 4th Ave Studio!

Garden Casita in City Center - 10yrs hosting

Charming Private Guesthouse with Mountain View
Guest house rentals with a patio

Coyote Cavern: A Southwestern High Desert Retreat

Guest Cottage located near University and Downtown

Cozy Casita Private Entry and Courtyard

*Prime Location: King Suite Guest House!*

Cute eco-built guesthouse

Midtown House near TMC & UofA•Fast WiFi •Self ChIn

The Tucson Bohemian Retreat w/Private Fenced Yard

Sunshine Loft
Guest house rentals with a washer and dryer

Solar Powered Guest House Near UA—No Cleaning Fee!

The Cottage

Cozy hideaway cottage in historic Ajo

Peaceful 4-Acre Desert Casita with Shared Hot Tub

Long term perfect: fenced, work desk, fast Wi-Fi

Blue Lake Boutique Hotel

Golden moments in Oro Valley/Tucson

Serene Desert Casita No cleaning fee, Pets welcome
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- University of Arizona
- Arizona-Sonora Desert Museum
- Tucson Botanical Gardens
- University of Arizona
- Reid Park Zoo
- Tumamoc Hill
- Titan Missile Museum
- Mission San Xavier del Bac
- Kino Sports Complex
- Tucson Convention Center
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- Rialto Theatre
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