
Guesthouse vacation rentals in Pima County
Find and book unique guesthouse rentals on Airbnb
Top-rated guesthouse rentals in Pima County
Guests agree: these guesthouse rentals are highly rated for location, cleanliness, and more.

The Zendo Oasis. Your Private Resort in Tucson.
Discover the Zendo Oasis, your private resort in midtown Tucson. Don't settle for a sterile hotel room that can cost hundreds more. The Zendo offers a retreat atmosphere that will impress. Exercise in our full gym and luxuriate in a hot stone sauna! After, jump in the pool! Sip wine while enjoying evenings around a chiminea under starlit skies. Lounge by the pool in the sun or shade on the deck or under louvered patios. The Zendo is close to the UA and downtown. Book now and escape the ordinary!

Peaceful Desert Oasis in Central Tucson Foothills
Newly renovated guest home located in a quiet central area in the Catalina Foothills. Trails and biking in our backyard, 10-15 min drive to hiking/parks, downtown and UofA! Away from everything and yet conveniently close to everything! Enjoy beautiful mountain views and professional landscaping. Well equipped kitchen with washer/dryer and a cozy fireplace and desk in the master bedroom. Lots of privacy from the main home. Stocked with all your amenities needed for a cozy and comfortable stay.

Studio in the Saguaro Forest
New modern studio guesthouse on 3.2 lush acres secluded at the edge of the Saguaro National Park! Cleaning fees included in nightly rate. Private indoor/outdoor living areas. 8 miles easy access to downtown, 9 miles to the Desert Museum. High speed Starlink WiFi, Tuft & Needle queen bed, washer/dryer combo, 4k smart TV, whisper quiet mini split, full size sleeper sofa for 3rd guest. Nice retreat from midtown traffic. Check out my other similar listing on the property. LICENSE: 21465687

West-side Trailhead Retreat in the Sonoran Desert
2017 guest house in Tucson Mountain foothills adjacent to Sweetwater Preserve (14+ mi.s of trails: mountain biking, horseback, running, & hiking)! Enjoy the giant soaking tub, BBQ grill, sunsets & patio. A full kitchen, sitting area, bath & BR are downstairs (550 sq. ft.). Up a 90-degree ladder to BR/retreat space, wonderful for getaway views. Our property is a 3-acre lot w/ desert flora/fauna, stars, & quietness, yet only 10 mi. from UA. Horses add to the ambiance with a taste of ranch life.

Dream House
Replenish * Re-calibrate * Reconnect.. Welcome to our little house of dreams! You have found the perfect leaping off point to explore all this region has to offer. Nestled snugly between the Patagonia and Santa Rita mountains, our casita sits at just under 5,000 ft, making it temperature perfect almost year round. Enjoy our 38 acres and private hiking trails right out the front door with endless possibilities for adventure. Recharge, Rejuvenate, and Revel in our cozy, clean, quite space.

Attractive Casita In Tucson
A charming getaway casita with stunning views of the majestic Saguaro National Park and the Picture Rock Mountains for spectacular sunsets. The 5-acre site is home to many varieties of cacti, including giant saguaros and other native plants and trees. Through the casita's panoramic windows, you can observe desert vegetation, birds, rabbits, coyotes, bobcats, javelinas, and deer. An evening bath in the jacuzzi under the starry sky will certainly remain in your memory for a long time.

The Coop- Luxury guest house with ideal location
This luxury guest home was originally a chicken coop for a farmer over 60 years who owned the majority of the land in the area. With an addition and a complete renovation, we have designed this for the perfect vacation rental ideally located in Tucson. 15 minutes to Banner and the U of A. 10 minutes to Oro Valley or the freeway. The stylish guest home is separated from our home and designed with privacy in mind. Enjoy this brand new house for your stay with experienced hosts.

Tucson Poet's Studio
Tucson Poet's Studio was featured in Architectural Digest (10-1-2025) “50 Best Airbnbs Across the United States", New York Magazine (6-19-2015) “Taste the Flavors of Tucson” and LivAbility (7-6-2018) “Accessible Airbnb” *NEW* EV Charger! The studio shares the private, walled courtyard and pool with the main house where my husband and I live. Located in the Peter Howell neighborhood, a convenient midtown area close to everything (2.5 mi to UA, 5 mi to downtown).

Time Capsule in the Sonoran Desert
Vibrant space-age cabin on an 11-acre desert art sanctuary near Saguaro National Park, 35 mins from Tucson! Features WiFi, AC/heat, outdoor bathroom deck & eco-amenities. Sits 15 yards from Groovy Glamper. 🚫 NO PETS/ESAs (Service Animals welcome). Delicate art decor makes this space strictly UNSUITABLE for children/minors. ⚠️ IMPORTANT: Before booking, note that check-in is strictly in person and no later than 10:00 PM. No exceptions!

Horse house
Welcome to your perfect getaway! This house is located in the heart of the city, giving you easy access to the best restaurants, shops, and local attractions. Enjoy the comfort of modern design with all the amenities you need for an unforgettable stay. The property has private parking, ideal for peace of mind, and a large outdoor space where you can relax, organize meetings, or simply enjoy the outdoors.

Peaceful Casita in the Foothills
Looking for a peaceful retreat in the foothills of the Catalina mountains? The Catalina Vista guest house offers sweeping views of the city and its just minutes to awesome hiking trails! Close to shopping, great restaurants, grocery stores and golf. Newly remodeled, the spacious Casita has a brand new queen size mattress and a small kitchen to prep quick meals (No Oven). The patio has great city views!

Spanish Bungalow Casita with Private Patio
This one of a kind Spanish Bungalow is among the finest accommodations in Tucson. Nestled in the heart of Tucson, distinguished by modern amenities and historic character. The Spanish Bungalow is located walking distance from Downtown, the best Mexican restaurants in the city and minutes away from the U of A, and so much more. Come relax and enjoy the thoughtful privacy this bungalow has to offer.
Popular amenities for Pima County guesthouse rentals
Family-friendly guest house rentals

Extra-Spacious 1BR Guesthouse Close to UA

Casita de Pomona

Charming Private Oasis Casita with Pool & Hot Tub

Blue Lake Boutique Hotel

Southwest Solitude

The Southwest Knest

Central Casita Minutes from UA & Downtown

Casita with Heated Salt Water Pool & Solar Power
Guest house rentals with a patio

Coyote Cavern: A Southwestern High Desert Retreat

Guest Cottage located near University and Downtown

Rustic Cabin with Mountain Views Close to Wineries

Spacious peaceful guesthouse

Midtown House near TMC & UofA•Fast WiFi •Self ChIn

Historic University area Downtown 4th Ave Studio!

The Tucson Bohemian Retreat w/Private Fenced Yard

Casita Chapulin
Guest house rentals with a washer and dryer

Solar Powered Guest House Near UA—No Cleaning Fee!

Oasis: Casita Colibrí - Little Hummingbird House

Peaceful, quiet getaway

Charming Indoor Jacuzzi & outdoor heated pool

Cozy Casita with Private Courtyard -5 Mins to UofA

Privacy, security, comfort, solar! Dog friendly!

TREAT GUEST HOUSE Private, Quiet, Comfortable

Luxe Large Loft in Central Tucson
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- University of Arizona
- University of Arizona
- Arizona-Sonora Desert Museum
- Tumamoc Hill
- Tucson Botanical Gardens
- Reid Park Zoo
- Titan Missile Museum
- Mission San Xavier del Bac
- Tucson Museum of Art
- Pima Air & Space Museum
- Tucson Convention Center
- Rialto Theatre
- Picacho Peak State Park
- Children's Museum Tucson
- Mini Time Machine Museum of Miniatures
- Tumacacori National Historical Park
- Trail Dust Town
- Mercado San Agustin
- Tubac Presidio State Historic Park
- Gene C Reid Park
- Tucson Mountain Park
- Rooster Cogburn Ostrich Ranch
- Red Hills Visitor Center
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