
Guesthouse vacation rentals in Pima County
Find and book unique guesthouse rentals on Airbnb
Top-rated guesthouse rentals in Pima County
Guests agree: these guesthouse rentals are highly rated for location, cleanliness, and more.

The Zendo Oasis. Your Private Resort in Tucson.
Discover the Zendo Oasis, your private resort in midtown Tucson. Don't settle for a sterile hotel room that can cost hundreds more. The Zendo offers a retreat atmosphere that will impress. Exercise in our full gym and luxuriate in a hot stone sauna! After, jump in the pool! Sip wine while enjoying evenings around a chiminea under starlit skies. Lounge by the pool in the sun or shade on the deck or under louvered patios. The Zendo is close to the UA and downtown. Book now and escape the ordinary!

Peaceful Desert Oasis in Central Tucson Foothills
Newly renovated guest home located in a quiet central area in the Catalina Foothills. Trails and biking in our backyard, 10-15 min drive to hiking/parks, downtown and UofA! Away from everything and yet conveniently close to everything! Enjoy beautiful mountain views and professional landscaping. Well equipped kitchen with washer/dryer and a cozy fireplace and desk in the master bedroom. Lots of privacy from the main home. Stocked with all your amenities needed for a cozy and comfortable stay.

West-side Trailhead Retreat in the Sonoran Desert
2017 guest house in Tucson Mountain foothills adjacent to Sweetwater Preserve (14+ mi.s of trails: mountain biking, horseback, running, & hiking)! Enjoy the giant soaking tub, BBQ grill, sunsets & patio. A full kitchen, sitting area, bath & BR are downstairs (550 sq. ft.). Up a 90-degree ladder to BR/retreat space, wonderful for getaway views. Our property is a 3-acre lot w/ desert flora/fauna, stars, & quietness, yet only 10 mi. from UA. Horses add to the ambiance with a taste of ranch life.

HummingBird Casita at Birdsong Retreat
Your private studio casita at Birdsong Desert Retreat: thoughtfully curated eclectic furnishings & decor, full kitchen, private bath—opening to serene desert views. Welcome with homemade grain-free granola, pancake mix, syrup, coffee & teas. On 40 peaceful acres: 360° vistas of Patagonia, Atascosa Mtns, Coronado Forest, Mt Wrightson & Mexico. Lake 6 min away. Dark-sky compliant—profound starry nights, nature sounds, monsoon storms & rainbows (Jul-Sep) for renewing energy. More at birdsongaz

Dream House
Replenish * Re-calibrate * Reconnect.. Welcome to our little house of dreams! You have found the perfect leaping off point to explore all this region has to offer. Nestled snugly between the Patagonia and Santa Rita mountains, our casita sits at just under 5,000 ft, making it temperature perfect almost year round. Enjoy our 38 acres and private hiking trails right out the front door with endless possibilities for adventure. Recharge, Rejuvenate, and Revel in our cozy, clean, quite space.

Time Capsule in the Sonoran Desert
The Time Capsule is a unique experience in a space age module dropped in the middle of an 11 acres desert sanctuary and sculpture park, adjacent to the Saguaro National Park. Enjoy the quietness of the desert in a safe environment located at just 35 minutes from downtown Tucson. Because of the refinement of the interior design, we cannot accept any pets in the Time Capsule. However, service animals are welcome. Please note that check-in is in-person only and not later than 10:00 PM.

Attractive Casita In Tucson
A charming getaway casita with stunning views of the majestic Saguaro National Park and the Picture Rock Mountains for spectacular sunsets. The 5-acre site is home to many varieties of cacti, including giant saguaros and other native plants and trees. Through the casita's panoramic windows, you can observe desert vegetation, birds, rabbits, coyotes, bobcats, javelinas, and deer. An evening bath in the jacuzzi under the starry sky will certainly remain in your memory for a long time.

The Coop- Luxury guest house with ideal location
This luxury guest home was originally a chicken coop for a farmer over 60 years who owned the majority of the land in the area. With an addition and a complete renovation, we have designed this for the perfect vacation rental ideally located in Tucson. 15 minutes to Banner and the U of A. 10 minutes to Oro Valley or the freeway. The stylish guest home is separated from our home and designed with privacy in mind. Enjoy this brand new house for your stay with experienced hosts.

Guest House with private courtyard, Saguaro Park
✷ Scenic Location ✷ Fastest WiFi ✷ Huge Outdoor Fully Fence Living Space ✷ Low cleaning fees ✷ Pet Friendly ✷ For more pictures and videos, find us on social media! Follow @casajaguartucson We believe that true peace is found through a connection to nature, in a home where every detail has been carefully considered. Welcome to Casa Jaguar, the ideal desert getaway located in Saguaro National Park for those seeking to reconnect with nature and revitalize their spirit.

Tucson Poet's Studio
Tucson Poet's Studio was featured in Architectural Digest (10-1-2025) “50 Best Airbnbs Across the United States", New York Magazine (6-19-2015) “Taste the Flavors of Tucson” and LivAbility (7-6-2018) “Accessible Airbnb” *NEW* EV Charger! The studio shares the private, walled courtyard and pool with the main house where my husband and I live. Located in the Peter Howell neighborhood, a convenient midtown area close to everything (2.5 mi to UA, 5 mi to downtown).

Saguaro Oasis Retreat near National Park
If you love nature this casita is just for you. Located 15 minutes from downtown and only a few minutes from stunning hiking and mountain biking trails in the National Park. The property is very much like a botanical garden with fruit trees filling up the back and a wide variety of succulents filling the front. The casita has its own private porch while the property shares two large communal patios with outdoor dining and a fire pit.

Horse house
Welcome to your perfect getaway! This house is located in the heart of the city, giving you easy access to the best restaurants, shops, and local attractions. Enjoy the comfort of modern design with all the amenities you need for an unforgettable stay. The property has private parking, ideal for peace of mind, and a large outdoor space where you can relax, organize meetings, or simply enjoy the outdoors.
Popular amenities for Pima County guesthouse rentals
Family-friendly guest house rentals

4th Ave & University - Pool + Hot Tub + Garage!

Casita de Pomona

Solar Powered Guest House Near UA—No Cleaning Fee!

Charming U of A Area Guesthouse

The Southwest Knest

Casita with Heated Salt Water Pool & Solar Power

Charming Desert Guesthouse

Private Casita in Casas Adobes
Guest house rentals with a patio

Coyote Cavern: A Southwestern High Desert Retreat

Guest Cottage located near University and Downtown

Rustic Cabin with Mountain Views Close to Wineries

Midtown House near TMC & UofA•Fast WiFi •Self ChIn

Historic University area Downtown 4th Ave Studio!

The Tucson Bohemian Retreat w/Private Fenced Yard

Sunshine Loft

Amazing Casita at the Tubac Resort-Self check-in*
Guest house rentals with a washer and dryer

Oasis: Casita Colibrí - Little Hummingbird House

Studio in the Saguaro Forest

Blue Lake Boutique Hotel

🌵 Central Desert Oasis 2 🌵

Positano

Peaceful, quiet getaway

Charming Indoor Jacuzzi & outdoor heated pool

Privacy, security, comfort, solar! Dog friendly!
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- University of Arizona
- University of Arizona
- Arizona-Sonora Desert Museum
- Tumamoc Hill
- Tucson Botanical Gardens
- Reid Park Zoo
- Titan Missile Museum
- Mission San Xavier del Bac
- Tucson Museum of Art
- Pima Air & Space Museum
- Tucson Convention Center
- Rialto Theatre
- Mini Time Machine Museum of Miniatures
- Children's Museum Tucson
- Picacho Peak State Park
- Tumacacori National Historical Park
- Trail Dust Town
- Tubac Presidio State Historic Park
- Mercado San Agustin
- Gene C Reid Park
- Tucson Mountain Park
- Rooster Cogburn Ostrich Ranch
- Red Hills Visitor Center
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