Guesthouse vacation rentals in Pima County

Find and book unique guesthouse rentals on Airbnb

Top-rated guesthouse rentals in Pima County

Guests agree: these guesthouse rentals are highly rated for location, cleanliness, and more.

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Top guest favorite

Guesthouse in Tucson

4.98 out of 5 average rating, 256 reviews

RetroTrek Bungalow Private-Fenced-Cozy

Our bungalow is nicely suited for 2, features a separate kitchen, a 3/4 bath, & large main room for sleeping or relaxing. We offer a private entrance with carport parking. Yard is fenced, with dog door, up to 2pets are welcome. Centrally located, within minutes of the airport, downtown and the University of Arizona. We are within walking distance to Reid Park for golfing or a visit to the Zoo. Even though we are midtown with easy access to many areas of town, you will find it surprisingly quiet.

Top guest favorite

Guesthouse in Tucson

4.98 out of 5 average rating, 592 reviews

TREAT GUEST HOUSE Private, Quiet, Comfortable

The entire guesthouse is in the centrally historic Sam Hughes neighborhood (527 N Treat Ave). Great community with lots of restaurants and markets nearby (4 min to Wholefoods). The host, a Swiss Photographer & artist, designed every amenity to enhance your vacation or business trip in Arizona's gem of a city. You won't want to leave from its practical kitchen to its richly tiled shower and memory foam bed. This unique accommodation will become one of the highlights of your Southwestern adventure

Top guest favorite

Guesthouse in Tucson

4.96 out of 5 average rating, 369 reviews

The Zendo Oasis. Your Private Resort in Tucson.

Discover the Zendo Oasis, your private resort in midtown Tucson. Don't settle for a sterile hotel room that can cost hundreds more. The Zendo offers a retreat atmosphere that will impress. Exercise in our full gym and luxuriate in an infrared or hot stone sauna! After, jump in the pool! Sip wine while enjoying evenings around a chiminea under starlit skies—lounge in the sun or shade on the deck or under louvered patios. The Zendo is close to the UA and downtown. Book now and escape the ordinary!

Top guest favorite

Guesthouse in Tucson

4.96 out of 5 average rating, 851 reviews

Tucson Poet's Studio

Tucson Poet's Studio was featured in Architectural Digest (1-19-2024) "59 Best Airbnbs Across the United States", New York Magazine (6-19-2015) “Taste the Flavors of Tucson” and LivAbility (7-6-2018) “Accessible Airbnb” *NEW* EV Charger! The studio shares the private, walled courtyard and pool with the Eucalyptus Suite Airbnb and the main house where my husband and I live. Located in the Peter Howell neighborhood, a convenient midtown area close to everything (2.5 mi to UA, 5 mi to downtown).

Guest favorite

Guesthouse in Tucson

4.86 out of 5 average rating, 188 reviews

Reflection House

This beautifully remodeled guest casita is centrally-located within Tucson. Walking distance to the Tucson Mall, the loop, many restaurants and parks. The gated community has a community pool/spa and dog run. The inner courtyard has a many plants and beautiful large quartz rocks. As you walk into your private entrance Studio you will see tile plank floor, a queen bed, 55in curve tv, dresser and a little desk. This room also has a kitchenette with quartz countertop and luxurious private bathroom.

Top guest favorite

Guesthouse in Tucson

4.96 out of 5 average rating, 795 reviews

Private Tucson Desert Guest House Getaway

This guest house is a pleasant desert retreat in Northeast Tucson, nestled on a large property with spectacular views of the Catalina Mountains. Minutes from from Sabino Canyon, Mt. Lemmon, and close to sumptuous dining. Guests will enjoy a recently space which includes a kitchenette complete with a microwave, coffee-maker, toaster oven, refrigerator, and more. Large bathroom and closet. Also available are a pool, BBQ grill, outdoor seating, and play yard. Laundry available upon request.

Top guest favorite

Guesthouse in Tucson

4.98 out of 5 average rating, 172 reviews

Straw bale guesthouse on Tucson's west side

Beautiful straw bale guesthouse with the best porch in the city! Enjoy incredible sunrises with sweeping views of the Tucson basin. Close to Sweetwater Preserve and Saguaro Nat'l Park West it makes for a perfect place to rest after a long day of hiking or mountain biking. Enjoy the peaceful nature of the country with convenience of being only 5 minutes from the freeway and a 15 minute drive to downtown. Private parking, a fully remodeled kitchen, 1 bedroom with king sized bed and day bed.

Top guest favorite

Guesthouse in Tucson

4.99 out of 5 average rating, 211 reviews

Cozy Mountain Retreat w/ Hot Tub

Come visit our small horse ranch in NW Tucson! Tucked into the foothills of the Santa Catalina Mountains, you’ll enjoy great views, and slightly cooler temperatures. You'll be close enough to town to have access restaurants,shopping, entertainment, etc, yet you'll have unlimited access to hiking and mountain biking right out our gate. * Not suitable for children under 12yrs. **This is a smoke-free property, sorry, no exceptions. *you must be able to climb a small flight of stairs*

Top guest favorite

Guesthouse in Tucson

4.99 out of 5 average rating, 361 reviews

Time Capsule in the Sonoran Desert

Time Capsule is a unique experience in an space age module dropped in the middle of an 11 acres desert sanctuary and sculpture park, adjacent to the Saguaro National Park. Enjoy the quietness of the desert in a safe environment located at just 35 minutes from downtown Tucson. Because of the refinement of the interior design we cannot accept any pet, service animal, nor children in the Time Capsule. Please note that check in is in person only and not later than 10:00PM. No exception!

Guest favorite

Guesthouse in Tucson

4.97 out of 5 average rating, 157 reviews

The Coop- Luxury guest house with ideal location

This luxury guest home was originally a chicken coop for a farmer over 60 years who owned the majority of the land in the area. With an addition and a complete renovation, we have designed this for the perfect vacation rental ideally located in Tucson. 15 minutes to Banner and the U of A. 10 minutes to Oro Valley or the freeway. The stylish guest home is separated from our home and designed with privacy in mind. Enjoy this brand new house for your stay with experienced hosts.

Top guest favorite

Guesthouse in Ajo

4.99 out of 5 average rating, 211 reviews

Cozy hideaway cottage in historic Ajo

Stay in a cozy, very private, window filled 500 sq. ft. hideaway cottage that is located on the property of a historic Ajo home. Located just 4 blocks from the gorgeous Spanish Revival town plaza, you can walk to Ajo's Visitors Center, art galleries, restaurants, library, and coffee shop or you can drive a mile to the Ajo Scenic Loop to savor and hike a portion of the pristine Sonoran Desert that rivals Organ Pipe Cactus National Monument. Let me welcome you to Ajo!

Top guest favorite

Guesthouse in Tucson

4.94 out of 5 average rating, 175 reviews

Private Casita in Casas Adobes

411sq ft private Casita just newly REMODELED! Sleeps up to 4. King feather bed & a pullout sleeper. Located just past a quaint garden where you can catch hummingbirds drinking. Private parking & entrance, just come and go. ASK ABOUT: Our other King Suite just feet away! Can sleep 2 more! Cool off in pool (rarely used by us), use outside patio (where cooking station is located, there's no kitchen in the casita). Min. from I-10 & stellar Tucson Biking Loop!!