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Vacation rentals in Panama Bay

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Top-rated vacation rentals in Panama Bay

Guests agree: these stays are highly rated for location, cleanliness, and more.

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Top guest favorite
Apartment in Panamá
4.98 out of 5 average rating, 228 reviews

In the heart of Casco, remodeled and with parking

Escape and discover the old town in this remodeled, comfortable and central accommodation in the heart of Casco Viejo. Our location is the best, it will make you come back. Close to restaurants, bars, impressive churches, and museums. The property dates back to the 17th century (1756) history and good atmosphere. You can explore the area on foot, fully equipped kitchen, European king bed, you will feel right at home, surrounded by the famous calicanto walls. -A large living room -Fully-equiped kitchen

Guest favorite
Apartment in Panamá
4.93 out of 5 average rating, 100 reviews

Apto 4 min from Tocumen Airport | 24-hr check-in

Layover in Panama? Stay where everything is easy and comfortable Just 4 minutes from Tocumen International Airport – perfect for early flights or quick stopovers A modern, comfortable, and secure apartment with: • Fast WiFi and air conditioning • Smart lock and flexible check-in • 24/7 security • Pool, gym, and fully equipped kitchen • Steps from the ITSE Metro station Ideal for layover travelers, curious tourists, or business trips. 🌴 Just arrive — everything’s ready for you. We’ll be waiting!

Superhost
A tranquil infinity pool is viewed from a sun deck featuring two lounge chairs. Lush greenery surrounds the area, and the Pacific Ocean is visible in the background, extending towards the horizon under a clear blue sky.
Villa in Saboga
4.7 out of 5 average rating, 46 reviews

Bahia Breeze 3 bdrm nature sanctuary with pool

Reconnect with nature in this spacious, serene private villa. Hiking, beach, sailing club, fishing or just relax in tranquility. Phenomenal views of Milky Way Galaxy at night. Watch Netflix or YouTube on big screen. Have a relaxing meal on the deck overlooking the Pacific. Tremendous effort to create a solar powered environmentally friendly private retreat immersed in nature. Depending on time of year, feel free to grab a papaya, lime, mango, avocado. Portion of proceeds to World Wildlife Fund

Top guest favorite
A communal rooftop space is revealed, showcasing several white-accented chairs and small tables arranged amidst potted plants. The backdrop features a panoramic view of the Panama City skyline against a clear blue sky.
Apartment in Panamá
5 out of 5 average rating, 58 reviews

Tropicool Loft w/rooftop steps from Casco

This historic 1941 loft is located at the entrance of Casco Viejo where you’re steps from the fish market and all the cool cafés, rooftops, and trendy restaurants that make up the neighborhood. Fully equipped kitchen, washer/dryer combo, 1.5 bath, bedroom on 2nd floor, 2 balconies + communal rooftop, projector w/Netflix, fast internet, and great AC. You’re also directly in front of the Cinta Costera park for running, biking, tennis courts. Near local airport for flights to Bocas!

Top guest favorite
Apartment in Panamá
4.96 out of 5 average rating, 27 reviews

Gorgeous Flat in the best location in Casco Viejo

This cute and stylish studio is perfectly located in the heart of Casco Viejo, Panama City’s most charming historic district. Recently renovated, it combines modern comfort with classic charm inside a beautiful colonial building—just steps from top restaurants, bars, monuments, and attractions. The space includes a comfortable sofa bed, making it ideal for a couple or a small family looking to enjoy the vibrant atmosphere of Casco right outside their door.

Top guest favorite
Apartment in Panama City
4.97 out of 5 average rating, 99 reviews

Amazing loft with an iconic view of Casco Viejo

Enjoy a unique experience, in this elegant and centrally-located loft. Fully remodeled 1 bedroom apartment, in a central location in Casco Viejo (the old city). You will be just steps away from many restaurants, cafes, museums, and the existing night life casco has to offer. Located in “Jeronimo,” this restored- colonial building was built in the year 1850, and features unique crafted wall décor, as well as some of the original "calicanto" walls.

Guest favorite
Apartment in Panamá
5 out of 5 average rating, 13 reviews

Private parking & rooftop | Studio Casco Center

This beautiful restored studio from the 1870s blends history with modern design. Enjoy a private rooftop terrace with seating and BBQ, plus private PARKING—ideal after exploring Casco's best restaurants, galleries, and nightlife steps away. ✨ Highlights: - Historic Charm: Original tile floors and exposed colonial stone walls. - Comfort: King bed, living room, and full kitchen. - Amenities: Private rooftop & private PARKING. - Great location

Superhost
The exterior view of a two-story villa is surrounded by tropical greenery and palm trees. Balconies are visible on both floors, showcasing wooden railings. The structure is nestled on a slope, blending harmoniously with its natural surroundings.
Home in contadora
4.85 out of 5 average rating, 231 reviews

villa in contadora, las perlas

a luxury villa, 2 stories, 2 decks, 2 bedrooms and two bath (one large one upstairs connected to masterbedroom and one small one downstairs), full kitchen, shared pool, private stairs down to beach, nice gardens, optional mule, cart rental. 1-6 people, might be requested Villa has private beach access and has nice views of the ocean from the upper deck. (pool is shared pool and we are not always informed on which days its out of service)

Superhost
A serene courtyard features a small pool surrounded by terracotta tiles and smooth wooden planks. Lush green plants are displayed throughout the space, enhancing the tranquil environment. The walls are adorned with original stonework, blending history with nature.
Home in Panama City
4.77 out of 5 average rating, 105 reviews

Cozy house in Casco Viejo with private pool

Historic accommodation in the heart of the Old Town Enjoy a unique experience in this accommodation located in the center of the Old Town. The property has been carefully restored several times by renowned Panamanian architects, including Sebastián Paniza. Among its most outstanding features is a historic well within the property, as well as original walls and floors that preserve the spirit and authenticity of the place.

Guest favorite
Apartment in Panamá
4.99 out of 5 average rating, 136 reviews

Full apartment in Panama

This charming apartment is located in one of the best neighborhoods in Panama, San Francisco, a downtown location where you will find ample cuisine, entertainment venues, close to bus stations, and the city's most important shopping mall, Multiplaza. This central and quiet apartment is an opportunity you won't want to miss. It offers the perfect combination of comfort, beauty, and a convenient location.

Guest favorite
The villa is nestled amongst lush greenery, with vibrant trees bordering a sandy beach. The crystal-clear water gently laps at the shore, leading to a spacious, modern home set back in the landscape, ensuring a private and serene environment.
Home in Saboga
4.92 out of 5 average rating, 26 reviews

Spectacular ocean view, private beach access, pool

Discover Saboga Island, home of the famous Survivor TV Show, in this magic property: Villa 'Corral Cove' is located in a pristine environment with a fantastic view of the beach. This 'architect' home has been built recently and has been decorated with style and comfort in mind. You will love the serenity of this unique place, perfect for resting and having unforgettable family moments.

Superhost
A private terrace features a jacuzzi surrounded by lush greenery against an exposed stone wall. Wooden decking creates a warm ambiance, complemented by two lounge chairs designed for relaxation, offering an inviting outdoor space for guests.
Apartment in Panama City
4.9 out of 5 average rating, 162 reviews

Jacuzzi in colonial ruins in beautiful apartment

Welcome to Casa Marquez Portazgo! This cozy apartment in the heart of Panama City offers comfort and convenience, ideal for your stay. With one bedroom and capacity for two people, you'll enjoy a relaxing atmosphere in 70 m². Located in the San Felipe neighborhood, just steps from the entrance to the Casco Antiguo, it offers a unique experience. You can also unwind in the jacuzzi.

Popular amenities for Panama Bay vacation rentals

  1. Airbnb
  2. Panama
  3. Panama Bay