
Vacation rentals in Osborn Medical Center, Phoenix
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Top-rated vacation rentals in Osborn Medical Center, Phoenix
Guests agree: these stays are highly rated for location, cleanliness, and more.

Best Little Guesthouse in Melrose !
Historic guesthouse in the heart of the Melrose District! EV charger! Walking distance to restaurants, bars, coffee shops, the famous Melrose Vintage shops, grocery stores, LA Fitness and more! Want to head downtown to Chase Field, Talking Stick Arena for a game or a show? Campbell Street Light Rail station is only five short blocks away! No need for a car, you can take the Light Rail from Sky Harbor International Airport, save your money for entertainment! Off street parking if you have a car!

Spacious Midtown guesthouse with full privacy
Welcome to your private casita (tiny home) in the heart of Midtown. Located right across the street from Starbucks, Buffalo Exchange, and the famous Taco Guild, relax comfortably with vaulted ceilings, a spacious layout, outdoor patio, and a quiet bedroom with a Queen-size bed — perfect for solo travelers or couples. Plus, the Light Rail station is walkable, which goes to Uptown, Downtown, the airport, Tempe, and Mesa. You are only: 7 mins to Downtown 9 mins to the Airport 15 mins to Scottsdale

PHX's Modern Midtown Carriage House, Free Parking
Experience the perfect blend of historic charm and modern comfort in the heart of Phoenix's Midtown. Our beautifully designed Carriage House offers a unique guest quarters, complete with a full kitchen, luxurious queen bedding, and a private patio. Step outside and explore the vibrant neighborhood, filled with local restaurants, shops, and cultural attractions. Book your stay at the Midtown Carriage House today and discover the best of Phoenix living. check out on insta @midtowncarriagehouse

Private, Sparkling Clean Historic DTPHX Guesthouse
This charming studio guesthouse in the Campus Vista historic district is a fantastic find! Situated in a friendly neighborhood in the heart of Phoenix, this newly remodeled living space is cozy and practical, surpassing many of the similar properties in quality and character. A short ten-minute drive from the Sky Harbor Airport, and located within walking distance to two major bus lines and the light rail, the guests are sure to enjoy the easy access to all the popular downtown destinations.

Private, desert-chic casita in vibrant Midtown PHX
Welcome to Casita Amelia, a modern rustic retreat central to all the action Phoenix has to offer. Welcoming and cozy, this newly updated private guest suite has all the luxuries of a modern hotel suite while being quietly tucked away in a cute Midtown neighborhood. Walk to Melrose District. You're also just 5-10 mins by car to Uptown & Camelback Corridor, 10 mins to Downtown (Footprint Center, Chase Field, Arizona Financial), 15 mins to Sky Harbor Airport, and 20 mins to State Farm Stadium.

Private Casita w/ Pool* & BBQ in Historic Melrose
*PLEASE READ HOUSE RULES IN "OTHER THINGS TO NOTE" AREA BEFORE BOOKING* Under no circumstance can one book the Airbnb for another guest . This violates our house rules as well as Airbnb policy. Read more under HOUSE RULES for more details. Our cozy casita is located in the Woodlawn Park neighborhood, a short car ride from the Melrose and Willo Districts. Located near some of the best restaurants in Phoenix, this is the perfect stay for visitors who want to explore the local food scene.

Converted 30s Historic Carriage House in Del Norte
Reliably operated by a top AZ Superhost with 4,400+ 5 star stays. Del Norte - the only historic district near downtown Phoenix to be surrounded by 3 green parks. This is a converted 1930’s carriage house (next to an English Revival Cottage) that was carefully curated with your rest and peace in mind. Exclusive designer finishes, with full functionality - fully stocked mini-kitchen, spa like bathroom. Patio seating in the shade to enjoy the AZ inside / outside living. INCLUDED 👇

Bungalow a Go-Go!
SPORTING Events-CONCERTS - ARTS!! This Urban Oasis is located in the hub of it all! Enjoy city views from this historical 1910 Bungalow, nestled in the coveted Willo Historical and midtown Arts District. Created to highlight the Bungalow’s original details with a perfect balance of modern design and historic charm. 2 patios. Bistro desert picnic area, and wood burning fire pit. 1 block from Lightrail and Heard Museum. 2 miles from Suns and Diamondback stadiums.

The Beverly Bungalow | Stylish Stay Near Downtown
Relax & unwind at our mid-century bungalow in the heart of Phoenix. This 1BR/1BA condo will comfortably sleep 2. Our condo is complete with a full kitchen, cozy living room & dedicated work space for the WFH professional. Also included is a shared pool/hot tub to cool off on those hot summer days. Located in Midtown center to museums, unique bar & restaurant concepts, Chase Field, The Footprint Center - the list goes on. We hope you enjoy all AZ has to offer!

Guesthouse in city's most walkable neighborhood
Central location, easy access to I-10, I-17, 202, 51, and 9 minutes from Phoenix Sky Harbor Airport. Amenities abound in this updated private studio guesthouse in the upscale Encanto-Palmcroft Historic District of downtown Phoenix. Homes here have stunning architectural diversity. Recently ranked the wealthiest neighborhood in Phoenix, Phoenix Magazine named Encanto-Palmcroft 2009's "Best Places to Live" and the "Best Neighborhood to Walk Through" in 2015.

Adorable Willo Cottage in Historic Central Phoenix
Peaceful one bedroom cottage in unbeatable location within Central Phoenix. Walking/ biking distance from light rail, restaurants, Heard Museum and Phoenix Art Museum. Enclosed backyard with a shared washer/dryer on property. The cottage has a queen bed, mini kitchen and private patio. Property is cleaned and sanitized according to the Airbnb cleaning procedures. 15 minutes from Sky Harbor Airport. 5 minutes from Encanto Park (Golf Course)

Historic Casa in heart of Phoenix
This newly restored 1930's home is loaded with charm and amenities. Situated on a quiet cul-de-sac in the upscale Willo neighborhood, our casa is just a walk or short light rail ride from the heart of downtown Phoenix. From this unique location you can enjoy it all in true Phoenician style - food, drinks, arts, culture, music and sports! Plus easy access to Scottsdale, Tempe, hiking, golf, shopping and airport in <10 mile radius.
Popular amenities for Osborn Medical Center, Phoenix vacation rentals
Other great vacation rentals in Osborn Medical Center, Phoenix

Cozy One Bedroom - King Bed

Midtown Apart ! Great Location !

Luxe Historic Casita w/ Free Parking: Casa Pascual

Historic Home Near Downtown | Full Kitchen & Patio

The "Blue Door" at 16th Dr.

Modern Chic Condo In Midtown w/ Pool & Hot Tub

High-End Cowboy Casita w/ Private Patio & BBQ

#1 Cozy Retreat
Destinations to explore
- Phoenix Convention Center
- Chase Field
- Lake Pleasant
- TPC Scottsdale - Champions Course
- Grayhawk Golf Club
- Tempe Beach Park
- The Westin Kierland Golf Club
- Sloan Park
- Peoria Sports Complex
- Salt River Fields at Talking Stick
- WestWorld of Scottsdale
- State Farm Stadium
- Arizona State University
- Salt River Tubing
- Camelback Ranch
- Surprise Stadium
- Scottsdale Stadium
- We-Ko-Pa Golf Club
- Goodyear Ballpark
- Hurricane Harbor Phoenix
- Papago Park
- Seville Golf & Country Club
- Trilogy Golf Club at Power Ranch
- Desert Diamond Arena




