
House vacation rentals in Mission
Find and book unique houses on Airbnb
Quick stats about house rentals in Mission

Total vacation rentals
Explore 160 vacation rentals in Mission

Verified guest reviews
Over 9,960 verified reviews to help you choose

Family-friendly vacation rentals
60 properties offer extra space & kid-friendly amenities

Pet-friendly vacation rentals
Find 30 rentals that welcome pets

Rentals with dedicated workspaces
110 properties have a dedicated workspace

Wi-Fi availability
160 of Mission vacation rentals include wi-fi access

Popular amenities for guests
Guests love Kitchen, Wifi, and Pool across Mission rentals

4.9 Average rating
Mission stays are highly rated by guests—averaging 4.9 out of 5!

Nearby attractions
Mission's top spots, include Four Barrel Coffee, Balmy Alley, and Valencia Street
Top-rated house rentals in Mission
Guests agree: these houses are highly rated for location, cleanliness, and more.

Stylish Spacious Garden Master Bedroom w/ en Suite
Studio (ground floor garage access) with a private bath, lush private patio. Bernal Hts is a hip village within San Francisco. With a choice of some of the hippest bars, restaurants, and parks Bernal's location has not only the convenience of an urban hub, but it has very easy access to public transport. The studio is always professionally cleaned. Expect down pillows and a down comforter and quality Parachute or Brooklinen bedding. **Entrance to bldg is shared - Entrance to the apt is private.

Noe Valley guest suite overlooking downtown
Enjoy the comfortable living room with stunning views of the San Francisco downtown skyline, and step outside to our patio with sweeping views of the bay. Our 2 bedroom home is conveniently located near the trendy shops and restaurants on 24th Street, as well as the beautiful Dolores Park, stunning views at Twin Peaks, and the peaceful trails of Glen Canyon. Whether you're exploring the city or enjoying a relaxing day at home, our house is the perfect home base for your San Francisco adventure.

Complete Separate Suite at Castro Oasis
Secured - completely separate and private enSuite w/bath in Updated Victorian home - access to washer/dryer, refrig, dining and work area, snacks, drinks, tea/coffee, Smart TV - Netflix, Prime Video, Hulu - Cable. Access to shared garden/decks. Ensuite is sleeping quarter within our Victorian home, close to but not adjacent to one used by owner who will be residing within and sharing the property with guests at the same time. Very private and quiet area. Walk to the heart of the Castro.

Magical Spacious Mission Victorian home
Welcome home to a piece of San Francisco history and magic. This stunning, 1800+ square foot house is part of just 5% of the city that fully withstood the 1906 and the Loma Prieta earthquakes, a mix of fortuitous geography and magic. For more than 15 years, it has been my sanctuary when the rough and tumble of the business world has kicked me in the stomach, when heartbreak hit, and later it was the co-parent in helping me raise my gorgeous girls. I'm ready to share its magic with you!

Private Suite & Entrance. No Shared Space.
Enjoy privacy in a newly renovated San Francisco guest suite. You will have your own entrance, bedroom & bathroom complete with a desk, sofa, & mini-fridge. Think of it like a boutique hotel room but cozier! Located in the sunny North Slope of Bernal Heights. Escape the fog and enjoy nearby parks, restaurants, and markets...many within a 5-minute walk. The Mission District is conveniently within walking distance so a number of highly-rated restaurants and cafes are easily accessible.

Lux Large 2BR, Separate Entry, New Renovation
Welcome to Potrero Hill! We are the sunniest neighborhood in the city and are perfectly located. Our home is 15 min walk to SF General Hospital, UCSF, Mission Bay, SOMA, and the Mission district. You will get an entire bottom floor of the house, fully separated from our home. Home is brand new, built in 2022. While you have total privacy, we are on site in case anything comes up. Parking is easy and we are near the freeways, making it easy to get to Silicon Valley, Marin, or Napa.

Elegant 2BR/2BA Panoramic View Parking • near BART
Renovated 2BR/2BA: Views, Terrace & Parking Enjoy this light-filled home featuring a 400 sq ft sunny terrace with sweeping views. Tucked in serene Sunnyside, the space boasts dramatic modern bathrooms, a spacious designer kitchen, and vaulted ceilings. Includes Sonic internet and a private driveway. Perfectly located: near transit, 15-min walk to Glen Park BART, and 20 minutes drive from SFO. Discover the Golden Gate or Sausalito ferry from your quiet, upscale SF sanctuary!

2br Victorian House with Breathtaking views
Amazing Victorian House on top of Potrero Hill one of the best places in San Francisco to have a magnificent view of the city. Spacious house with terrace and garden. Fast Wifi, parking for free 24/7, smart tvs with fire stick. Very close to downtown, the Mission, Castro, Ferry building, AT&T Giants, Chase Center, general hospital, UCSF, just 15 minutes from the airport. Great restaurants, wineries, parks and the historic Anchor Steam Factory in the neighborhood.

• Spacious 1 Bed Suite in Painted Lady-Duboce Park
Cozy and comfortable suite in a Victorian Painted Lady! Nicely furnished and equipped apartment in the center of a Historical District. Your spacious flat is comfortable, private, secure and centrally located with access to Muni Metro, Bart, UCSF, USF, Alamo Square, Moscone Center, Hayes Valley, NOPA and the Haight Ashbury. Virtually every cool neighborhood in SF is easy to get to from here! Perfect for romantic getaways, corporate travel, or family vacations.

Luxurious garden oasis in the heart of SF
Experience a classic Victorian cottage, recently updated with high-end, modern amenities. This spacious garden oasis in central Noe Valley also boasts spectacular downtown views. Shopping/restaurants are just a few minutes walk away; public transport is even closer. The private deck off the dining room is nestled in the redwoods; there's off-street parking and optic fiber internet. Your entrance and living space are at street level.

Guest Perch · Dolores Park/Castro/Noe · Hot Tub
· Superfast Gigabit WiFi ‧ Host Full-Service Departure Cleaning ‧ Resplendent in warmth, light, verdant plants, objets d'art, and white oak finishes, the Guest Perch is a tranquil one-bedroom and full bath reprieve after an adventurous day in San Francisco. Stroll to Noe Valley, Castro, and Valencia neighborhoods. Easy access to MUNI, BART, Uber/Lyft, car rental, and bike share transportation options.

Stunning Home above Dolores Park w/Sweeping Views
A beautiful, fully remodeled 2-story Edwardian home in San Francisco's historic Liberty Hill. Large decks with panoramic downtown views. Ideally located on Liberty Street, steps away from MUNI and walking distance from Dolores Park, the Mission, Noe Valley, and the Castro. Perfect for a couple or small family. Parties or events not allowed.
Popular amenities for Mission house rentals
House rentals with a pool

MidCentury Modern w/Pool, Spa & Mountain Views

Summer-house/OASIS on quiet street in ROCKRIDGE!

4-5 bedrm, 4-5 bath luxury home with pool, hot tub

Luxury sleep in Baby Bears Den

New Sleep in Lux Berkeley spot

Beautiful Views San Francisco Bay

3BD House near Golden Gate Park !

San Francisco Suburb, Community Pool & Tennis
Weekly house rentals

Bernal Heights Nest -Top Location!-

Total Gem Two Bedroom Home

Stunning Bernal Views • Spacious 3BR- Near Mission

Lovely, Unique Home Near Everything

Bright & Modern Home w/ Views! Mins to Twin Peaks

Potrero Hill Garden Viewpoint

1906 Victorian in Noe Valley!

Garden Retreat steps from Haight St
Private house rentals

Pacific Heights Grand Victorian Top Floor Kitchen

Lovely Arts & Crafts home on quiet Castro street

The Hidden Gem At Nob Hill in the Heart of SF

Modern 3 bedrooms 2 baths private flat on 2nd FL

Gorgeously Renovated Coastal Victorian Home

Experience Noe Valley from Stylish and Private House

Two Creeks Treehouse

Spacious, stylish, cozy 1 bedroom in Potrero Hill
Destinations to explore
- Rentals with breakfast Mission District
- Private suite rentals Mission District
- Smoking-friendly rentals Mission District
- Rentals with a washer and dryer Mission District
- Rentals with a patio Mission District
- Rentals with outdoor seating Mission District
- Pet-friendly rentals Mission District
- Condo rentals Mission District
- Family-friendly rentals Mission District
- Apartment rentals Mission District
- Rentals with a fire pit Mission District
- Fitness-friendly rentals Mission District
- Rentals with a fireplace Mission District
- House rentals San Francisco
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- Stanford University
- Golden Gate Park
- Muir Woods National Monument
- Golden Gate Bridge
- Oracle Park
- Moscone Center
- University of California-Berkeley
- SAP Center
- Levi's Stadium
- Mission Dolores Park
- Pier 39
- Six Flags Discovery Kingdom
- Chase Center
- University of California San Francisco
- California’S Great America
- Palace of Fine Arts
- Rodeo Beach
- Montara Beach
- Painted Ladies
- Bolinas Beach
- Baker Beach
- Big Basin Redwoods State Park
- San Francisco Zoo
- Oakland Arena





