House vacation rentals in Mission

Find and book unique houses on Airbnb

Quick stats about house rentals in Mission

Total vacation rentals
Explore 160 vacation rentals in Mission
Verified guest reviews
Over 9,960 verified reviews to help you choose
Family-friendly vacation rentals
60 properties offer extra space & kid-friendly amenities
Pet-friendly vacation rentals
Find 30 rentals that welcome pets
Rentals with dedicated workspaces
110 properties have a dedicated workspace
Wi-Fi availability
160 of Mission vacation rentals include wi-fi access
Popular amenities for guests
Guests love Kitchen, Wifi, and Pool across Mission rentals
4.9 Average rating
Mission stays are highly rated by guests—averaging 4.9 out of 5!
Nearby attractions
Mission's top spots, include Four Barrel Coffee, Balmy Alley, and 16th Street / Mission Bart Station

Top-rated house rentals in Mission

Guests agree: these houses are highly rated for location, cleanliness, and more.

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Top guest favorite

A spacious living area features a sectional sofa with colorful cushions, paired with a matching armchair. A patterned ottoman sits in front of the seating, while natural light floods through large windows. Warm wood beams accent the ceiling, creating a cozy ambiance.

Home in Bernal Heights

Stylish Spacious Garden Master Bedroom w/ en Suite

Studio (ground floor garage access) with a private bath, lush private patio. Bernal Hts is a hip village within San Francisco. With a choice of some of the hippest bars, restaurants, and parks Bernal's location has not only the convenience of an urban hub, but it has very easy access to public transport. The studio is always professionally cleaned. Expect down pillows and a down comforter and quality Parachute or Brooklinen bedding. **Entrance to bldg is shared - Entrance to the apt is private.

LocationFamilyBathroom

4.91 out of 5 average rating, 577 reviews

Guest favorite

A panoramic view of the San Francisco skyline is presented at dusk, with sparkling city lights contrasted against a soft, colorful sky. The glittering bay is visible in the background, bordered by scenic hills and a sprawling neighborhood below.

Home in Noe Valley

Noe Valley guest suite overlooking downtown

Enjoy the comfortable living room with stunning views of the San Francisco downtown skyline, and step outside to our patio with sweeping views of the bay. Our 2 bedroom home is conveniently located near the trendy shops and restaurants on 24th Street, as well as the beautiful Dolores Park, stunning views at Twin Peaks, and the peaceful trails of Glen Canyon. Whether you're exploring the city or enjoying a relaxing day at home, our house is the perfect home base for your San Francisco adventure.

LocationValueLong stay

4.87 out of 5 average rating, 276 reviews

Top guest favorite

Home in San Francisco

Complete Separate Suite at Castro Oasis

Secured - completely separate and private enSuite w/bath in Updated Victorian home - access to washer/dryer, refrig, dining and work area, snacks, drinks, tea/coffee, Smart TV - Netflix, Prime Video, Hulu - Cable. Access to shared garden/decks. Ensuite is sleeping quarter within our Victorian home, close to but not adjacent to one used by owner who will be residing within and sharing the property with guests at the same time. Very private and quiet area. Walk to the heart of the Castro.

ValueLocationGetting around

4.98 out of 5 average rating, 680 reviews

Top guest favorite

A light-filled living room features a large sectional sofa and two vintage armchairs facing a decorative fireplace. The space is complemented by a coffee table, with art pieces and framed photos adorning the walls, and large windows allowing natural light.

Home in Inner Sunset

Walk to Golden Gate Park from a Radiant Home

Experience the best of classic and contemporary style in our bright and spacious home. Enjoy meals in the gourmet kitchen opening to a light-filled room or step onto the deck for coffee overlooking the garden. The open floor plan connects a formal dining room and living room with beautiful period details. Retire upstairs to the large master bedroom connected to a luxurious bathroom. Two spacious bedrooms offer comfort and privacy overlooking a quiet garden and sharing a second full bathroom.

FamilyLocationCleanliness

4.97 out of 5 average rating, 364 reviews

Top guest favorite

A spacious living room is accented by vibrant green walls and hardwood parquet flooring. Light fills the room through large bay windows, framing views of the neighborhood. A stylish couch and chairs provide seating options, while a decorative fireplace and indoor plants add character.

Home in Mission

Magical Spacious Mission Victorian home

Welcome home to a piece of San Francisco history and magic. This stunning, 1800+ square foot house is part of just 5% of the city that fully withstood the 1906 and the Loma Prieta earthquakes, a mix of fortuitous geography and magic. For more than 15 years, it has been my sanctuary when the rough and tumble of the business world has kicked me in the stomach, when heartbreak hit, and later it was the co-parent in helping me raise my gorgeous girls. I'm ready to share its magic with you!

ValueFamilyLong stay

4.94 out of 5 average rating, 104 reviews

Top guest favorite

A bright living area is presented, featuring a spacious sectional sofa paired with a wood coffee table. The modern kitchen is visible in the background, equipped with stainless steel appliances. Vibrant artwork adorns the walls, complementing the open dining space with a wooden table and black chairs.

Home in Potrero Hill

Lux Large 2BR, Separate Entry, New Renovation

Welcome to Potrero Hill! We are the sunniest neighborhood in the city and are perfectly located. Our home is 15 min walk to SF General Hospital, UCSF, Mission Bay, SOMA, and the Mission district. You will get an entire bottom floor of the house, fully separated from our home. Home is brand new, built in 2022. While you have total privacy, we are on site in case anything comes up. Parking is easy and we are near the freeways, making it easy to get to Silicon Valley, Marin, or Napa.

LocationFamilyCleanliness

4.97 out of 5 average rating, 120 reviews

Top guest favorite

Home in San Francisco

Elegant 2BR/2BA Panoramic View Parking • near BART

Renovated 2BR/2BA: Views, Terrace & Parking Enjoy this light-filled home featuring a 400 sq ft sunny terrace with sweeping views. Tucked in serene Sunnyside, the space boasts dramatic modern bathrooms, a spacious designer kitchen, and vaulted ceilings. Includes Sonic internet and a private driveway. Perfectly located: near transit, 15-min walk to Glen Park BART, and 20 minutes drive from SFO. Discover the Golden Gate or Sausalito ferry from your quiet, upscale SF sanctuary!

LocationFamilyBathroom

4.98 out of 5 average rating, 121 reviews

Top guest favorite

A bright dining area features a wooden table surrounded by black chairs. Large windows and skylights allow natural light to fill the space. Green plants are displayed, and a cozy seating nook with cushions is visible. A sliding door leads to a deck area.

Home in Potrero Hill

2br Victorian House with Breathtaking views

Amazing Victorian House on top of Potrero Hill one of the best places in San Francisco to have a magnificent view of the city. Spacious house with terrace and garden. Fast Wifi, parking for free 24/7, smart tvs with fire stick. Very close to downtown, the Mission, Castro, Ferry building, AT&T Giants, Chase Center, general hospital, UCSF, just 15 minutes from the airport. Great restaurants, wineries, parks and the historic Anchor Steam Factory in the neighborhood.

FamilyLocationCheck-in

4.97 out of 5 average rating, 277 reviews

Top guest favorite

Two wicker chairs are positioned around a small table on a concrete patio, creating a cozy outdoor seating area. A window nearby allows natural light to enter, while a white door leads inside. Simple arrangements enhance the space for relaxation.

Home in Bernal Heights

House on the hill

Tucked beneath The House on the Hill in Bernal Heights, this private downstairs guest space offers a cozy San Francisco stay with charm, comfort, and easy city access. Set within a classic Victorian hillside home, guests enjoy a private entrance through the side garden gate, comfortable furnishings, and a peaceful atmosphere. Minutes from cafés, parks, transit, the Mission District, and downtown, it’s the perfect neighborhood retreat with a true local feel.

ValueFamilyParks

4.96 out of 5 average rating, 101 reviews

Guest favorite

A bright corner of the room is enhanced by large windows that open to a balcony. A mural of a woman’s face is mounted on the wall above a large potted plant. Natural light highlights textured rugs and organic shapes of seating elements.

Home in San Francisco

Guest Perch · Dolores Park/Castro/Noe · Hot Tub

· Superfast Gigabit WiFi ‧ Host Full-Service Departure Cleaning ‧ Resplendent in warmth, light, verdant plants, objets d'art, and white oak finishes, the Guest Perch is a tranquil one-bedroom and full bath reprieve after an adventurous day in San Francisco. Stroll to Noe Valley, Castro, and Valencia neighborhoods. Easy access to MUNI, BART, Uber/Lyft, car rental, and bike share transportation options.

LocationValueHeating

4.95 out of 5 average rating, 481 reviews

Guest favorite

A formal dining room features a long wooden table surrounded by several chairs, with a yellow accent chair included. Large windows provide natural light and showcase views of the surroundings, while built-in cabinetry offers ample storage space. The wood flooring adds to the room's elegant design.

Home in San Francisco

Stunning Home above Dolores Park w/Sweeping Views

A beautiful, fully remodeled 2-story Edwardian home in San Francisco's historic Liberty Hill. Large decks with panoramic downtown views. Ideally located on Liberty Street, steps away from MUNI and walking distance from Dolores Park, the Mission, Noe Valley, and the Castro. Perfect for a couple or small family. Parties or events not allowed.

LocationValueBreakfast

4.93 out of 5 average rating, 316 reviews

Top guest favorite

A dining area features a round wooden table surrounded by four chairs. Large windows provide expansive views of the hilltop neighborhood, allowing natural light to fill the space. A vase with fresh flowers is centered on the table, enhancing the ambiance of the room.

Home in Bernal Heights

Stunning Bernal Views • Spacious 3BR- Near Mission

Quiet cul-de-sac home with beautiful city views, with nearby staircases leading down toward the Mission. Three bedrooms with queen beds (two upstairs, one main floor). The home offers a spacious layout. Fully furnished in a peaceful residential neighborhood. Street parking is generally easy and convenient.

FamilyLocationGetting around

4.99 out of 5 average rating, 176 reviews