
House vacation rentals in Little Italy
Find and book unique houses on Airbnb
Quick stats about house rentals in Little Italy

Total vacation rentals
Explore 80 vacation rentals in Little Italy

Nightly prices starting at
Little Italy vacation rentals start at G$12,549 GYD per night before taxes and fees

Verified guest reviews
Over 6,950 verified reviews to help you choose

Family-friendly vacation rentals
50 properties offer extra space & kid-friendly amenities

Pet-friendly vacation rentals
Find 30 rentals that welcome pets

Rentals with dedicated workspaces
40 properties have a dedicated workspace

Wi-Fi availability
80 of Little Italy vacation rentals include wi-fi access

Popular amenities for guests
Guests love Kitchen, Wifi, and Pool across Little Italy rentals

4.8 Average rating
Little Italy stays are highly rated by guests—averaging 4.8 out of 5!
Top-rated house rentals in Little Italy
Guests agree: these houses are highly rated for location, cleanliness, and more.

Walk to Balboa Park and Hillcrest from an Immaculate Home
Take a stroll through the park, then unwind with a leisurely dinner under the festoon lights. Classic crown molding, hardwood floors, and pared-back tones of gray and taupe create an air of calm at this elegant haven spread out over 1500 square feet. You will find the space charming & spacious with over 1500 sq. feet. This single level property is the lower level of a historic duplex. Hardwood floors, crown molding, gas fireplace and laundry room. Street parking is usually readily available. This A+ location of Banker's Hill is NOT impacted by air plane noise. Enjoy the entire lower level duplex and use of the back yard with patio set for dining. Please note the upper tenant may also want to use this space so this area could be shared. We would love to greet you but are also fine with allowing you to access with a code on the front door. We live nearby and are happy to make suggestions for dining or things to do. Located near numerous restaurants, and Balboa Park, Hillcrest, the zoo, Downtown, Little Italy, and the Convention Center are all within 10 minutes. Be at the beach in less than 15 minutes. The bus line runs up First Ave for easy access to Downtown and Uptown. Near trolley and train station. We are within 10 minutes to the San Diego International Airport and a quick Uber ride to Downtown, Little Italy. Walk to the heart of Hillcrest, Balboa Park and the Zoo. Be at the beach in less then 15 minutes. Central location near the I-5, I-163 & I-8. Because of the hardwood floors, you will hear the footsteps above. The kitchen is well stocked if your a cook and we have an area where you can set up your laptop. wireless available and 3 smart TV's for your enjoyment. Small market less than 1 block away.
4.95 out of 5 average rating, 368 reviews
Admire Harbor Views from the Porch at a City Gem
Unwind in a cozy colorful casita in this light-filled 1920s Spanish bungalow decorated with Mexican folklorico. Take a walk into Little Italy for dinner. Or to a show at the Old Globe.What’s best, is how close you are to so much, all without needing a car. A very small single car garage is provided, think compact car. Street parking is free but challenging at times. The house is located directly below the incoming flight path. You are encouraged to read the reviews regarding this.Ideal for four.
4.96 out of 5 average rating, 511 reviews
1stResorts.com WATERVIEW FAMILY VILLA HOT TUB YARD
Brand New FAMILY Villa: Full kitchen, Private back deck off living space & Private yard! Private Hot tub/fire pit & outdoor furniture! Near Sea World, the Zoo, other great activities for children & great restaurants! Near Little Italy, Balboa Park, Liberty Station, Seaport Village! 2 bedrooms w/king beds, 1 full bathroom w/shower & double sinks. Powder room, free private washer/dryer. Private Barbecue grill. Beach towels, queen pullout sofa bed. Back deck connected to living area & private yard!
4.94 out of 5 average rating, 102 reviews
Little Italy Historical
This AirBNB residence is a recently fully renovated historical property in San Diego’s Little Italy community. Many say it’s one of the finest. It is only 3 short blocks from Little Italy’s vibrant India Street and its many restaurants, bars, cafes, and shops, and four from the Trolley. It’s also a short drive to San Diego’s beaches and attractions. The AirBNB unit is a ground floor private one bed/one bath suite with a living room and its own entrances. Pics and descriptions are enclosed.
4.98 out of 5 average rating, 112 reviews
Central Little Italy Bayview House
There’s no better place to experience San Diego’s iconic Little Italy neighborhood than this remodeled bayview home. Located in the heart of Little Italy, a stone’s throw away from renowned restaurants, bars, boutiques, and antiques. A 5 minute drive from SAN, a 10 minute walk to the San Diego Harbor, and a 2 minute drive to the I-5 make all of San Diego immediately accessible. Close to Balboa Park, SD Zoo, & Downtown SD. The property has a parking spot, in-unit laundry, & a private patio.
4.9 out of 5 average rating, 165 reviews
Ventana Vista | Ocean View | EV Charger | Designer
@ventanacollection This cliff-side Mission Hills home is a light filled and custom designed to elevate your future vacation rental expectations. Highlights: - Ocean views from every room - Outdoor patio w/propane firepit and Grill - Modern fully stocked open kitchen with high-end Thermador appliances - Theatre Quality 75" TV and speakers in the plush living room - Premium work from home sit/stand desk, monitor, computer, webcam, speaker set up - Helix and Sleep Night memory foam mattresses
4.97 out of 5 average rating, 287 reviews
Stunning Mansion by The ConventionC & LittleItaly
Stunning Mansion perfect families and professionals!! Right by the Convention Center, Little Italy, Balboa Park within minutes of all SD attractions and beaches with the best Amenities and two parking spaces. Classic architecture combined with high end living, from the towels and sheets to the appliances and chef's kitchen. San Diego Mansion will make your experience one to remember. Large living and dining room, games, poker, piano, Hot Tub all this and more in the Perfect Location!
4.89 out of 5 average rating, 147 reviews
#1 LOCATION - Rare Luxury Home in Downtown
***THE BEST RATED RENTAL IN DOWNTOWN SAN DIEGO*** Location doesn't get better than this! Right in the heart of the lively Little Italy area in downtown San Diego. San Diego's best restaurants and nightlife in your backyard. Just blocks from the waterfront and a short Uber or walk to the Gaslamp, Convention Center & Zoo! All the frills: + Prime location! 98/100 Walker Score rating + Private parking + Private Sundeck & Backyard Stay at this modern luxury home for your next trip!
4.9 out of 5 average rating, 761 reviews
Little Italy 2BR Loft Near Waterfront & Convention
Discover the heart of San Diego from our spacious loft in Little Italy, the culinary gem of downtown. Perfectly situated for both business and leisure travelers, you're steps away from the waterfront, convention center, and vibrant city life. Embrace the urban experience with convenience at your doorstep, including eclectic bars and restaurants. We provide a white noise machine and earplugs, though the lower floor offers a quieter retreat. Experience the best of city living!
4.83 out of 5 average rating, 225 reviews
The Island View Penthouse
⸻ Welcome to our sophisticated three-bedroom, three-bath retreat in historic Bankers Hill. Enjoy sweeping views, a full modern kitchen, and spacious living areas perfect for relaxing or entertaining. Located just minutes from Balboa Park, downtown, and San Diego’s best dining, this home blends comfort, convenience, and classic neighborhood charm. All rooms feature luxury beds from Davenport Collection. We require minimum 2-night minimum per City code, and a $299 cleaning fee.
4.98 out of 5 average rating, 132 reviews
Downtown View - 2 Story House Next to Little Italy
Two story house with 2 living rooms; 3 blocks to Little Italy restaurants, bars, & shops. Near Balboa Park, San Diego Zoo, Gaslamp, Waterfront Park & the Harbor. Museums, restaurants, theaters & nature are all nearby. Located in historic Bankers Hill, next to Interstate 5, near the airport and city center. With 2 living rooms, my house is perfect for travelers needing separate space. One parking spot is available. Extra large vehicles will have to park on the street.
4.98 out of 5 average rating, 320 reviews
San Diego House: City Views, BBQ & Free Parking!
Experience the best of San Diego living in our conveniently located Victorian home in the prestigious Banker’s Hill neighborhood. 🏡 The home boasts breathtaking views of the San Diego Bay and downtown skyline 🌊✨ from its private balconies, classic charm with original moldings, high ceilings, and hardwood floors, plus modern amenities like a fully equipped kitchen and dining area. 🍴 The location couldn’t be more perfect — steps to Balboa Park, Little Italy, and Downtown!
4.84 out of 5 average rating, 423 reviewsPopular amenities for Little Italy house rentals
House rentals with a pool

Your Modern Lux Pool Resort in the Heart of SD
4.9 out of 5 average rating, 185 reviews
1 bedroom, 1 bath /Hillcrest/San Diego Zoo/Balboa
4.99 out of 5 average rating, 191 reviews
Lionhead - Private Boutique Home
4.93 out of 5 average rating, 293 reviews
Cozy University Heights Cottage
4.86 out of 5 average rating, 124 reviews
Designer Luxury Rental With Pool
4.94 out of 5 average rating, 147 reviews
Resort Living: Hoops, Outdoor Bar, Views, Pool+Spa
4.95 out of 5 average rating, 246 reviews
Stylish Family Home I Near Dining, Shopping + Zoo
4.95 out of 5 average rating, 198 reviews
Midcentury Lux 4BR home w Pool/Spa/Cabana/Firepit
5.0 out of 5 average rating, 299 reviewsWeekly house rentals

Tranquil 4 Bedroom w/ Deck & Backyard
4.79 out of 5 average rating, 127 reviews
Beautiful Canyon Cottage located on a huge lot
4.96 out of 5 average rating, 163 reviews
NEW Luxury 3BR HOUSEof DT Walk Petco w/Garage AC
4.91 out of 5 average rating, 211 reviews
Designer Unit w/FirePit-Petco Park, Zoo, Downtown
4.97 out of 5 average rating, 118 reviews
Pool Oasis in Central Hillcrest by Park/Zoo
4.92 out of 5 average rating, 183 reviews
Bright & Modern OB Getaway
4.98 out of 5 average rating, 129 reviews
Hot Tub Oasis | Walkable North Park | Top 1%
5.0 out of 5 average rating, 190 reviews
Amazing Design Downtown Sleeps 8
4.95 out of 5 average rating, 283 reviewsPrivate house rentals

Executive home - wooded urban oasis
4.88 out of 5 average rating, 187 reviews
Modern ❤️ of South Park, SD skyline, private patio
4.94 out of 5 average rating, 331 reviews
Golden Hill Tree House
4.99 out of 5 average rating, 435 reviews
The California
4.97 out of 5 average rating, 143 reviews
Condé Nast Villa | Speakeasy · Hot Tub · Sleeps 10
4.98 out of 5 average rating, 200 reviews
Mission Hills 3BR • Panoramic Views & Sunsets
4.94 out of 5 average rating, 167 reviews
Elevated Mission Hills Oasis: 4BR Balconies Views
4.97 out of 5 average rating, 139 reviews
Little Italy 3BD Home with Huge Patio + Backyard!
4.96 out of 5 average rating, 73 reviewsDestinations to explore
- Rentals with a sauna Little Italy
- Pet-friendly rentals Little Italy
- Rentals with a hot tub Little Italy
- Apartment rentals Little Italy
- Rentals with beach access Little Italy
- Family-friendly rentals Little Italy
- Condo rentals Little Italy
- Hotel rooms Little Italy
- Loft rentals Little Italy
- Rentals with pools Little Italy
- Rentals with breakfast Little Italy
- Waterfront rentals Little Italy
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- SeaWorld San Diego
- Coronado Beach
- Rosarito Beach
- LEGOLAND California
- University of California-San Diego
- Petco Park
- San Diego Zoo
- San Diego Convention Center E Ent
- San Diego Zoo Safari Park
- Pacific Beach
- Tijuana Beach
- Balboa Park
- San Diego State University
- Torrey Pines State Beach
- Mission Beach
- Ocean Front Walk
- Oceanside City Beach
- Las Olas Resort & Spa
- La Misión Beach
- Moonlight State Beach
- Belmont Park
- Sesame Place San Diego
- South Mission Beach, San Diego
- Oceanside Harbor





