Vacation rentals in Lee County

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Top-rated vacation rentals in Lee County

Guests agree: these stays are highly rated for location, cleanliness, and more.

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Superhost
The kitchen features wooden cabinetry and a granite countertop, complemented by stainless steel appliances. A large window provides natural light, while a bar seating area includes a bowl as a decorative touch. Essential cooking tools and amenities are readily accessible.
Home in Sumter
4.9 out of 5 average rating, 70 reviews

(#03) Home in Quiet Area 'NO cleaning fee'

Relax with the whole family at this peaceful place to stay. This modern 3 bedroom, 2 bath home away from home is perfect for any family looking to stay in a quiet and safe neighborhood 5 mins away from central area. This home includes a living room with a smart tv perfect for watching movies, a backyard patio with shade and a fireplace to set the vibe, a kitchen with basic cooking essential and a coffee station to make delicious coffee in the mornings. As well as a laundry room and study space!

Guest favorite
A newly renovated home with a brick facade is set on a spacious lawn, framed by trees. A wide driveway leads to a garage, and the house features multiple windows that allow natural light to fill the interiors.
Home in Mayesville
4.9 out of 5 average rating, 21 reviews

The Mayesville - Sumter-Florence Family Getaway

Newly renovated Home in quiet Mayesville, SC. is close to Sumter, Florence, Bishopville, Lake City, Lynchburg and Interstates 95 and 20. This is the perfect vacation spot for families reuniting for reunions, visiting relatives, day visits to Myrtle Beach, and just to get away. This home sports 2 closed in porches, 3 bedrooms, 8 beds, laundry room and yard for play area. If you don't want to be cramp up in a 1 room hotel and want to enjoy your family from a distance, this home is perfect.

Superhost
A warmly lit living area features two brown leather sofas facing a central coffee table. A decorative rug adds color to the hardwood floor, while a large mirror enhances the space. Windows allow natural light, complementing the cheerful yellow walls.
Home in Sumter
4.73 out of 5 average rating, 37 reviews

Carolina Breeze*Pool Military & Nurse Specials

*Special Rates* Military Nurses Corporate Summer Pristine newly renovated 4 bedroom 3 full baths home. Hardwoods and tile throughout, equipped with 5 large flat screen TVs, oversized eat in kitchen, large morning room for lounging and a mother in law suite. Pool house with half bath just steps away. Fully furnished, lovely living areas and a second dining area. Complete laundry room, all the amenities of home. Take a dip in our pool! Ample Parking and large fenced backyard! You will enjoy

Guest favorite
A comfortable living area is presented, featuring a plush blue sofa adorned with decorative pillows. A mounted TV is visible on the wall opposite. Natural light enters through a window covered by white blinds, complementing the neutral color palette of the room.
Guest suite in Lynchburg
4.9 out of 5 average rating, 41 reviews

Duck View Cottage (B) Tranquil & Wooded , All New

Cottage style home (Duplex), with an acre of wooded space. This will make you want to Kick back and relax. Quiet and Tranquil. Just off I-95 (exit 146), 2 miles of country road to the property The nearest gas station and grocery store are 3 miles away. Plus close to Florence (exit 157) and Darlington. Plenty of parking for larger vehicles with trailers, plus easy in and out with circular drive way. 10%off for 7+ days, 25% for 14+ Days, please inquire with questions, Smoke Free Cottage / No Pets

Top guest favorite
A contemporary one-story home features a striking blue-grey exterior with white shutters and large windows. A set of stairs leads to a welcoming front entry, surrounded by a lush green lawn and neatly arranged shrubs, providing a serene country aesthetic.
Home in Camden
5 out of 5 average rating, 33 reviews

Twin Cedars - less than a mile to Broomsedge Golf!

Incredible Retreat in Camden! Enjoy this perfect country escape, just 15 minutes from Camden and less than 1 mile from the new Luxury Broomesedge Golf Course! This newly remodeled home offers modern comforts in a peaceful setting, complete with access to a Tesla charger and the option for guided hunting tours on privately owned acreage. Located only 20 miles from Shaw Air Force Base, it’s ideal for golfers, families, or anyone seeking a quiet getaway in nature with beautiful horizon views.

Top guest favorite
Apartment in Hartsville
5 out of 5 average rating, 22 reviews

Private apartment minutes from Darlington Raceway

Enjoy a peaceful stay at this quaint 2-bedroom apartment in the countryside of Hartsville. The cozy space features 2 queen beds, 2 full bathrooms, and essential amenities like a washer/dryer, smart TV, and WiFi. Experience what Hartsville has to offer with a stay at our welcoming apartment. Walk out of the front door to a beautiful view of our pond. Owners live in the main house of the property, but you will have access to a private apartment with it's own entrance in a separate building.

Home in Hartsville
5 out of 5 average rating, 4 reviews

Cozy Nook

Enjoy the comforts of Home in this peaceful and updated home. Our cozy nook sits in the corner of a quiet neighborhood minutes from the Hospital and 4 miles from downtown Hartsville. The neighborhood does have some chickens; the home is brick with dual pane windows to dampen outside noise!. The Kitchen is setup for cooking and has all the basics. The back porch is covered and has seating and a propane grill. The entire house is yours for your stay. We have board games for your use.

Guest favorite
Home in Bishopville
5 out of 5 average rating, 5 reviews

Rustic getaway 20 mins from Camden and Hartsville

Relax with the whole family at this peaceful retreat in the country. Great location, 20 minutes from historic Camden, 45 minutes from Columbia and Florence. Ample space for parking an extra vehicle or livestock trailer while not in use. Enjoy country living in between your destinations for a few days, or while visiting family or going to events nearby. Enjoy evenings on a spacious back screen porch. Equipped with high speed internet and a spacious desk to work remotely if need be.

Superhost
A spacious outdoor pool is visible, featuring clear blue water and a diving board at one end. Surrounding trees provide partial shade, and a basketball hoop is positioned nearby on a concrete area.
Home in Sumter
4.83 out of 5 average rating, 41 reviews

Large Private Ranch W/ Pool

Spacious ranch home, perfect for families or small groups. Features 4 bedrooms (2 king beds, 2 queen beds), 3 bathrooms, and 1 bedroom doubles as a home office. Not a large pool with a diving board (opens in April for the season), basketball hoop, screened-in patio, fire pit, and small gas grill. Located minutes from Shaw Air Force Base, shopping, and dining. Large fenced yard, laundry room with washer/dryer, and ample parking make this the ideal retreat for work or relaxation.

Superhost
Guesthouse in Sumter

Rapsody among Nature

Kick back and relax in this calm, stylish space. Hard to believe you get so much for so little. Can sleep up to 6 adults (two queen two pullouts). Live amongst nature (5 acres) but close to Shaw AFB, Sumter, Eastover. 2 living rooms one upstairs bath. Upstairs has own kitchen, living room bedroom and dining. Downstairs has its dining, game room kitchenette. Formally a garage behind the "big house" now a get away with its own entrance. Be among the first to be our guest!!

Cabin in Dalzell
5 out of 5 average rating, 3 reviews

The Cabin at High Meadow Farm

The Cabin at High Meadow is a quiet 100 acre country escape, originally built in the 1940s and thoughtfully cared for to preserve its simple charm. This is a place to slow down, unplug, and return to the basics of unhurried time with your family, peaceful surroundings, and rest for the soul. It was built in another era, and we’ve kept much of its original charm. Consider indoor glamping with modern comforts. It’s not polished perfection, it’s peaceful authenticity.

Top guest favorite
A living room area features a red couch and a beige sofa, arranged near a wooden table on a patterned rug. A brick fireplace is flanked by a standing lamp. A television is mounted on the wall, and a set of French doors provides access to another room.
Home in Hartsville
4.97 out of 5 average rating, 128 reviews

Cozy little home away from home

This little gem is sure to make you feel at home! Our Barefoot Bungalow sits on a quiet residential street just 3 minutes from downtown Hartsville. The beds are comfortable, the couch is just waiting for you to settle in, and the kitchen was set up by two people who LOVE to cook. There's even an outdoor space to have a quick meal or enjoy the cool of the evening. This is my little dream cottage and I am so happy to be able to share it with you!

Popular amenities for Lee County vacation rentals