Vacation rentals in Lee County

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Top-rated vacation rentals in Lee County

Guests agree: these stays are highly rated for location, cleanliness, and more.

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Guest favorite
A newly renovated home with a brick facade is set on a spacious lawn, framed by trees. A wide driveway leads to a garage, and the house features multiple windows that allow natural light to fill the interiors.
Home in Mayesville
4.89 out of 5 average rating, 19 reviews

The Mayesville - Sumter-Florence Family Getaway

Newly renovated Home in quiet Mayesville, SC. is close to Sumter, Florence, Bishopville, Lake City, Lynchburg and Interstates 95 and 20. This is the perfect vacation spot for families reuniting for reunions, visiting relatives, day visits to Myrtle Beach, and just to get away. This home sports 2 closed in porches, 3 bedrooms, 8 beds, laundry room and yard for play area. If you don't want to be cramp up in a 1 room hotel and want to enjoy your family from a distance, this home is perfect.

Guest favorite
A comfortable living area is presented, featuring a plush blue sofa adorned with decorative pillows. A mounted TV is visible on the wall opposite. Natural light enters through a window covered by white blinds, complementing the neutral color palette of the room.
Guest suite in Lynchburg
4.92 out of 5 average rating, 36 reviews

Duck View Cottage (B) Tranquil & Wooded , All New

Cottage style home (Duplex), with an acre of wooded space. This will make you want to Kick back and relax. Quiet and Tranquil. Just off I-95 (exit 146), 2 miles of country road to the property The nearest gas station and grocery store are 3 miles away. Plus close to Florence (exit 157) and Darlington. Plenty of parking for larger vehicles with trailers, plus easy in and out with circular drive way. 10%off for 7+ days, 25% for 14+ Days, please inquire with questions, Smoke Free Cottage / No Pets

Guest favorite
The kitchen showcases wooden cabinetry with a mix of open shelving and closed storage. A stainless steel dishwasher and sink are located under a window, while countertop appliances and utensils are organized on the counters. Natural light fills the space, enhancing the warm wood tones.
Home in Hartsville
5 out of 5 average rating, 10 reviews

Spacious west side home travelers welcome king bed

Just right for your Hartsville area stay. Older style home that is a good fit for contract professionals and other travelers looking for a short term place. NOT able to walk to lake. One accessible lake IS located 6 miles away. One unaccessible lake is located 2 miles away. Hardwood floors, large capacity refrigerator, dedicated office, and den area make this place nice. A comfortable, economical home to accommodate you when you come to town for work, family visits, temporary assignments, etc.

Top guest favorite
An aerial view of a log cabin features a green metal roof and is surrounded by open farmland. The cabin is set back from a gravel driveway, with trees in the background and a well-defined yard, showcasing the spacious outdoors.
Cabin in Hartsville
5 out of 5 average rating, 65 reviews

Cozy Log Cabin retreat on a farm.

2 BR 1 Bath log cabin built in 2016 sitting on 100 acres of beautiful farmland surrounded by horse pastures, crop fields, gigantic pecan trees that line the 1/4 mile gravel drive and woods. Sit on the screened front porch in the morning, sipping coffee and watch the horses grazing peacefully in the pasture. Serene retreat for those looking for a secluded area to just get away from it all for a while. Please check out our Guest Book for local Businesses, restaurants and things to do in town.

Top guest favorite
A spacious living room features a comfortable sectional couch and two accent chairs set around a round coffee table. A wall-mounted TV is visible, while a ceiling fan and decorative wall accents enhance the inviting atmosphere. Natural light enters through the windows, complemented by soft drapes.
Home in Dalzell
5 out of 5 average rating, 29 reviews

Affordable, Pet Friendly w/ Fenced Yard, King bed

Kick back & relax in this calm, stylish space. A fenced in backyard for dogs and comfy beds makes this place the ultimate retreat. The kitchen is fully-equipped with everything you need. Enjoy the luxurious new couch while watching your favorite show using the 55” inch smart TV with access to Disney+, HBO Max, Hulu & Amazon Prime. The office is the perfect space for those needing to work from home or have a quiet space to sit & read your favorite book. This home is a little slice of heaven!

Top guest favorite
A contemporary one-story home features a striking blue-grey exterior with white shutters and large windows. A set of stairs leads to a welcoming front entry, surrounded by a lush green lawn and neatly arranged shrubs, providing a serene country aesthetic.
Home in Camden
5 out of 5 average rating, 27 reviews

Twin Cedars - less than a mile to Broomsedge Golf!

Incredible Retreat in Camden! Enjoy this perfect country escape, just 15 minutes from Camden and less than 1 mile from the new Luxury Broomesedge Golf Course! This newly remodeled home offers modern comforts in a peaceful setting, complete with access to a Tesla charger and the option for guided hunting tours on privately owned acreage. Located only 20 miles from Shaw Air Force Base, it’s ideal for golfers, families, or anyone seeking a quiet getaway in nature with beautiful horizon views.

Top guest favorite
Apartment in Hartsville
5 out of 5 average rating, 7 reviews

Private apartment minutes from Darlington Raceway

Enjoy a peaceful stay at this quaint 2-bedroom apartment in the countryside of Hartsville. The cozy space features 2 queen beds, 2 full bathrooms, and essential amenities like a washer/dryer, smart TV, and WiFi. Experience what Hartsville has to offer with a stay at our welcoming apartment. Walk out of the front door to a beautiful view of our pond. Owners live in the main house of the property, but you will have access to a private apartment with it's own entrance in a separate building.

Superhost
A spacious outdoor pool is visible, featuring clear blue water and a diving board at one end. Surrounding trees provide partial shade, and a basketball hoop is positioned nearby on a concrete area.
Home in Sumter
4.79 out of 5 average rating, 34 reviews

Large Private Ranch W/ Pool

Spacious ranch home, perfect for families or small groups. Features 4 bedrooms (2 king beds, 2 queen beds), 3 bathrooms, and 1 bedroom doubles as a home office. Not a large pool with a diving board (opens in April for the season), basketball hoop, screened-in patio, fire pit, and small gas grill. Located minutes from Shaw Air Force Base, shopping, and dining. Large fenced yard, laundry room with washer/dryer, and ample parking make this the ideal retreat for work or relaxation.

Superhost
Guesthouse in Sumter
New place to stay

Rapsody among Nature

Kick back and relax in this calm, stylish space. Hard to believe you get so much for so little. Can sleep up to 6 adults (two queen two pullouts). Live amongst nature (5 acres) but close to Shaw AFB, Sumter, Eastover. 2 living rooms one upstairs bath. Upstairs has own kitchen, living room bedroom and dining. Downstairs has its dining, game room kitchenette. Formally a garage behind the "big house" now a get away with its own entrance. Be among the first to be our guest!!

Guest favorite
A dining area is highlighted by a wooden table surrounded by six chairs. A floral centerpiece decorates the table, while a chandelier hangs overhead. Natural light filters through a large arched window, illuminating the space in soft tones.
Home in Sumter
4.84 out of 5 average rating, 37 reviews

(#5) Alluring Away home (No cleaning fee)

Home away from home perfect for families looking for a peaceful and safe neighborhood! Modern 3 bedroom, 2 bath home away from home 5 mins away from town. This home includes a living room perfect for family time supplied with a smart tv perfect for watching movies, a backyard patio with shade away from the sun and lights to set the vibe, a kitchen with basic cooking essential and a Keurig coffee station to make delicious coffee in the mornings. As well as a laundry room!

Superhost
A cozy living area features a pair of grey sofas facing a white coffee table, with a decorative tray on top. Soft curtains frame the windows, and a small plant adds a touch of greenery. An air conditioning unit and a flat-screen TV are mounted on the walls.
Apartment in Hartsville
4.82 out of 5 average rating, 11 reviews

Comfy 2Bedroom Gem in Hartsville

Keep it simple at this peaceful and centrally-located place. Centrally located in the city limits of Hartsville, this charming 2 bedrooms, 1 bathroom unit exudes comfort and simplicity. Located close to Neptune Island Waterpark, Darlington Raceway, Coker University and other attractions, this lovely home is the perfect stay to unwind.

Guest favorite
A cozy living room is presented, featuring a comfortable sectional sofa and two armchairs arranged around a wooden coffee table. A ceiling fan provides circulation, and a decorative fireplace serves as a focal point. Natural light filters in through windows, enhancing the welcoming ambiance.
Home in Dalzell
4.95 out of 5 average rating, 154 reviews

Home away from home

Forget your worries in this spacious and serene space. A quiet neighborhood conveniently located close to Shaw Air Force base and within minutes to major hospitals and shopping. Please read: If you have more than two pets you will need to be pre approved. Pet fee is $15 per pet / stay

Popular amenities for Lee County vacation rentals