Vacation rentals in Lake Keowee

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Top-rated vacation rentals in Lake Keowee

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Top guest favorite
A serene lake view is captured at sunset, featuring a dock and pavilion extending into the water. Lush grasses and landscaped stones frame the scene, as warm sunlight bathes the area in golden tones, enhancing the tranquil atmosphere of the shoreline.
Cottage in Six Mile
4.99 out of 5 average rating, 208 reviews

Lake Keowee Waterfront Cottage - Private Retreat

Lake-front retreat w/ unbelievable sunsets, swimming & kayaking, tucked in between the Cliffs & the Reserve, 30 miles west of Greenville. Private park-like setting for a couples getaway. Updated one-bedroom small cottage w/ living room, kitchen, bath, laundry, AC/heat. The entire property is included w/ your cottage rental; 1.1 acres, 800 ft of lake shoreline, a dock, a pier, a sunset deck, a social pavilion, waterfront hot-tub. It is a private lake experience; nothing really compares - unique!

Top guest favorite
A spacious outdoor dining area is featured on the deck, with ornate metal chairs surrounding a large table. The sun sets over the tranquil lake, casting a warm glow through the trees and reflecting on the water.
Home in Six Mile
5.0 out of 5 average rating, 42 reviews

Lakefront luxury home w/panoramic view & Boat Slip

You can’t get closer to the lake than this! While enjoying coffee or drinks anywhere on the huge wrap around deck, you’ll feel like you’re literally on the water with the beautiful panoramic lake views. This home has lots of indoor and outdoor entertaining space and is located in the premier mid section of the lake. You’re close to everything including Clemson University (Only 9 miles away), incredible hiking/biking in the nearby Blue Ridge mountains, shopping, restaurants, breweries & wineries!

Top guest favorite
An open living space is highlighted by a cozy sofa and bar stools at a kitchen counter. A dining area with chairs is visible in the background, alongside a staircase leading to an upper level with wood accents and natural light from multiple windows.
Cottage in Seneca
5.0 out of 5 average rating, 90 reviews

Keowee Waterfront Lakeside Retreat -Keowee Cottage

Lake Keowee Lake Side Retreat! Keowee Cottage is nestled in a lovely cove on a privately owned 20+ acre property. Explore native, natural beauty in this forested setting featuring nature trails, lake access, a sandy shoreline, firepit, & great views. Shared use of the lakeside Pavilion is an added bonus. The cottage features open living, dining, & a well-equipped kitchen. Please note there is no boat dock, however there is trailer parking on-site & several nearby boat ramps. We are dog friendly!

Top guest favorite
The treehouse rests elevated among dense trees, featuring a wooden deck with railing and steps leading to the ground. A circular stone fire pit is located at the base, surrounded by gravel, providing an inviting outdoor gathering space.
Treehouse in Seneca
5.0 out of 5 average rating, 72 reviews

Treehouse at Keowee Hollow

Welcome to the treehouse at Keowee Hollow!!! A CHARMING space nestled in a hollow - with a view of Lake Keowee - perfect for a ROMANTIC getaway or a peaceful retreat. This COZY, brand new, 1 bedroom, 1 bath treehouse offers rest and relaxation. Perfect location. We are minutes from Seneca, 10 miles from Clemson, under an hour to downtown Greenville, Highlands or Cashiers. The outdoor seating area is a perfect place to unwind at the end of a busy day, also features a fire pit & outdoor grill.

Top guest favorite
A treehouse surrounded by trees glows gently with warm lights in the evening. Two Adirondack chairs are positioned around a fire pit, with a small table nearby. The forest setting offers a calm and inviting atmosphere for outdoor relaxation.
Treehouse in Mountain Rest
5.0 out of 5 average rating, 482 reviews

THE BELLA LUNA Romantic Treehouse - Outdoor Shower

This is the perfect ROMANTIC ESCAPE! Located in the Sumter National Forest the Bella Luna is just 5 minutes from Stumphouse Tunnel, Issaqueena Falls, Yellow Branch Falls hiking trail, and Stumphouse Mountain Bike Park and within an hour of Clemson, Lake Jocassee and Clayton, GA. Our romantic retreat features carefully curated vintage furnishings, an outdoor shower, napping net, relaxing seating areas and an outdoor fire pit stocked with firewood and a S’mores kit! We can't wait to host you!

Guest favorite
Dome in Salem
4.88 out of 5 average rating, 390 reviews

Farm Geodome Near Lake Jocassee, Hot Tub, Zip Line

Glamping: where luxury meets the outdoors. This geodesic structure offers a rare opportunity to experience the outdoors without the elements. Complete with kitchen, AC & heat, dual control heated mattress pad, fully functioning bathroom, and sunrise views over the pasture. Whether you are looking to relax and enjoy feeding the farm animals, have an adventure riding the zip line, or indulge in a romantic evening sipping wine in the hot tub under the stars, you will leave with lasting memories.

Top guest favorite
A landscaped outdoor area features a winding pathway surrounded by mulch and greenery. Comfortable seating is arranged under the shade of trees, providing views of the lake. The water is visible beyond the trees, with structures in the background suggesting recreational activities.
Home in West Union
4.93 out of 5 average rating, 160 reviews

Dujardins Keowee Waterfront Home

2 night min. Deep water lot on Lake Keowee with double dock, and tons of entertaining space. On the main level, the great room/dining room is open to the kitchen. 4 bedrooms total, 3 king bedrooms (2 on first floor), 1 king and a bunk room with 2 doubles and 2 singles. A canoe, 2 paddle boards and 2 double kayaks included. Shuffleboard, foosball, outdoor Ping-Pong, board games and two person pac-man game, with additional 60 games! towels and linens included! Pickleball/tennis 10 min away!

Top guest favorite
A charming cabin is nestled among tall trees, accessed by a stone path. Warm string lights adorn the porch area, creating a welcoming glow. Fallen leaves blanket the ground, complementing the natural surroundings and inviting a sense of tranquility.
Cabin in Pickens
4.98 out of 5 average rating, 295 reviews

The Romantic Greystone Cottage

Follow the enchanting stone path to a private getaway where romance and connection await. Enjoy the ambiance of the starlit sky while cuddled up on the hammock or around the fire. Cozy up on the king-size bed and relish every moment of your stay. Indulge in a bottle of wine and relax by soaking in the luxurious claw-foot tub. Wake up to the tranquil sounds of the forest, savoring the morning with coffee on the porch. Escape the everyday and embrace what matters most at The Greystone Cottage.

Superhost
Home in Six Mile
4.83 out of 5 average rating, 271 reviews

House on Lake Keowee swim beach in cove w/ Dock

This two story home is located at the end of a very quiet cove with plenty of water. The beach has a fresh 6 inches of sand installed for the lake season. The walk to the lake is very short on an almost flat surface. The home will accommodate a family up to six people. The house has two floors. The main floor has a large living room with plenty of comfortable seating and satellite TV service provided. The entire main floor has hard woods along with the Master Bed Room and bed room #2.

Top guest favorite
Cabin in Tamassee
4.97 out of 5 average rating, 180 reviews

A Lakefront Tiny Cabin • Hot Tub • Kayaks • Canoe

Wake up to peaceful lake views, sip coffee on the porch, and spend the day kayaking or swimming from your private dock at Whitewater Cabin. This lakefront cabin is tucked away on a private Lake in the South Carolina mountains, minutes from Lake Jocassee, and sleeps 6. It’s the perfect getaway for couples, families, or friends looking to escape into nature. After a day exploring waterfalls, hiking, or boating on Lake Jocassee, come back and unwind in the hot tub overlooking the water.

Guest favorite
A spacious sunken living area features a large brick fireplace as a central focal point, flanked by two inviting seating arrangements. Natural wood beams extend across the ceiling, and light fills the space through multiple large windows, creating a warm and welcoming environment.
Home in Seneca
4.93 out of 5 average rating, 73 reviews

Lakefront Mid-Century Dream Home / 3 mi to Clemson

We excitedly invite you to come enjoy a one of a kind experience at our personal lakefront home. Originally designed and built in the 60s, this home now has all the modern necessities, yet still brims with endless midcentury charm. Located only 3 miles from Clemson, our large outdoor entertainment space and direct access to our private dock invite you to enjoy the many sights and sounds that the lake has to offer. Use our 2 kayaks and canoe, or use the dock to tie up your own boat!

Top guest favorite
Tiny home in Seneca
5.0 out of 5 average rating, 44 reviews

Near Clemson/Lake Keowee, Firepit, WiFi, Parking

Two bedroom, near lake, quiet location. Perfect for couples, small families or Clemson fans. Fast WiFi, self check-in, parking * Oconee Memorial Hospital 4 miles *Clemson is 13 miles *Historic Seneca is a 10 minute drive *Mountains are a short drive away *Local waterfalls Other Things you will love………… *Explore mountain towns of Cashiers, Highlands, Helen GA and many more *Little German town of Helen 45 min away *Go antiquing in Walhalla, SC *Enjoy good local cuisine .

Popular amenities for Lake Keowee vacation rentals

Frequently Asked Questions

  • Where is Lake Keowee located?

    Lake Keowee is in northwestern South Carolina, surrounded by the foothills of the Blue Ridge Mountains. The lake is near the towns of Seneca and Salem, giving visitors access to small-town atmospheres alongside natural scenery.

  • When is the best time to visit Lake Keowee?

    Late spring through early fall is often recommended for Lake Keowee, as temperatures typically range from 65–90°F (18–32°C) with comfortable water conditions. Mild autumn weather invites changing foliage, while summer has warm afternoons for swimming and boating.

  • What are some things to do near Lake Keowee?

    Around Lake Keowee, you can explore hiking trails, enjoy boating or fishing, and visit state parks with picnic spots and scenic overlooks. The area also has local markets, golf courses, and spaces for water sports and kayaking.

  • How is the weather near Lake Keowee?

    Lake Keowee has mild winters, with January lows near 33°F (1°C) and highs around 53°F (12°C), while summers are warm and humid, reaching up to 90°F (32°C) in July. Rain is spread throughout the year, with slightly drier months in early fall.

Destinations to explore