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Vacation rentals in Isla Iguana, Guna Yala, Panamá

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Top-rated vacation rentals in Isla Iguana, Guna Yala, Panamá

Guests agree: these stays are highly rated for location, cleanliness, and more.

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Top guest favorite
Boat in San Blas Islands
5 out of 5 average rating, 8 reviews

Private Catamaran live on board

Welcome aboard catamaran Yoyo, your floating home in the San Blas Islands. Your stay includes breakfast and snacks, with an optional meals and drinks package for USD 80 per person per day. For stays of 5 or more days, meals and drinks are included. Spend your days swimming, snorkeling, fishing, exploring hidden beaches, or relaxing on deck, and your nights unwinding under the stars. Experience the perfect blend of adventure, freedom, and laid-back island living with all the comfort you need.

Top guest favorite
Villa in Panamá
5 out of 5 average rating, 11 reviews

Casa Condal - Your Private Nature Eco-Retreat

Escape the noise, break your routine, and connect with nature at Casa Condal—a modern luxury retreat hidden inside Chagres National Park ✔ WiFi ✔ 65" Smart TV and Sound Bar ✔ Self check-in ✔ Private parking ✔ Fully equipped kitchen ✔ 220mts private trail ✔ Deck-Mirador with FirePit and panoramic view of the mountains and valley ✔ King bed + Full size sofa bed ✔ Wheelchair accessible 40 min from Tocumen Airport. Ideal for Birdwatchers, or a romantic getaway away from the city hectic rhythm.

An aerial view showcases a rustic cottage surrounded by lush palm trees, located near a sandy beach. The gentle waves of the ocean are visible, along with several red-roofed structures nestled within the greenery, creating a serene coastal atmosphere.
Cottage in Palenque
4.87 out of 5 average rating, 95 reviews

Beachfront House in Caribbean sandy beach

Enjoy this rustic and cozy cottage with its almost private beach surrounded by beautiful palm trees along the whole area. With 2 oceanview bedrooms, 2 full bathrooms and a third bedroom in a mezzanine. Has a patio with a built in uruguayan parrilla, ideal for BBQs. Step in beautiful white sand and bath in crystal clear water. Coconut breakfasts watching the sunrise become a routine in this paradise. - This is a rural setting. Not a 5 star hotel. Insects and small animals can be around.

Guest favorite
A stone pathway leads through lush tropical foliage toward a welcoming entrance. Tall trees and vibrant greenery frame the path, creating a serene approach to the property, which is partially visible in the background, surrounded by nature's tranquility.
Home in Panama City
4.96 out of 5 average rating, 83 reviews

Mountain Retreat

Relax and unwind at this peaceful property nestled on two hectares of lush tropical vegetation surrounded by the sights & sounds of nature. Located at Panama's Blue Mountain(Cerro Azul), 30 kilometres from Panama City. This cozy & comfortable home is equipped with modern amenities & chic decorative touches. It consists of a main house with 2 bedrooms & a 2 bedroom cottage. It has a spacious terrace, pool & jacuzzi overlooking Panama City. The property also boasts its own spring water well

Superhost
An aerial view captures the lush greenery of Narasgandub Island, surrounded by vibrant turquoise waters. The shoreline features a sandy beach bordered by palm trees, creating a tranquil atmosphere. The clear ocean extends into the horizon, highlighting the island's secluded paradise appeal.
Hut in San Blas
4.78 out of 5 average rating, 142 reviews

Bliss in the San Blas Islands

Discover Panama's best-kept secret in San Blas Islands, a set of 365 Caribbean Islands for 365 days of sun. All the Islands are owned by natives, "The Gunas," who will be very keen to welcome you and share their culture. Enjoy our crystal clear water, beautiful sunshine, and white sand, and wake up in the morning to hear the waves of the Ocean and see spectacular scenery from your room. A well-hidden Paradise awaits you in this unforgettable trip that will give you memories for a lifetime.

Guest favorite
A private hot tub sits at the edge of a tranquil lake, surrounded by lush greenery. The serene water reflects the clear blue sky, while the distant hills provide a peaceful backdrop. The tub's blue tiles contrast with the natural landscape.
Cabin in Panama City
4.91 out of 5 average rating, 67 reviews

#1 Cabin on the Lake Cerro Azul

Escape to the tranquil beauty of Cerro Azul, Panama and stay in our cozy lakeside cabin. With breathtaking views of the surrounding mountains and direct access to the lake, this is the perfect retreat for nature lovers. Enjoy fishing, kayaking, or simply relax on the private dock and soak in the serenity of the surroundings. Our fully equipped cabin has everything you need for a comfortable stay, including a full kitchen, comfortable bedroom, and a spacious balcony with panoramic views.

Guest favorite
A charming stone house is surrounded by lush greenery. The swimming pool is framed by several vibrant blue and yellow chairs, inviting relaxation. Large windows allow natural light to brighten the interior, while flowering plants add a touch of nature.
Cottage in Panamá
4.94 out of 5 average rating, 36 reviews

Cerro Azul, Country House with Heated Pool.

Check-in 9:00 AM Check-out 5:00 PM. Relax with the whole family and friends in this cozy country house. We have a heated pool, a 100-meter covered terrace to celebrate your special occasions (ice machine included), and a person (not mandatory) at your disposal during the day for cleaning and to assist you with everything you need to make your stay pleasant and unforgettable, where tranquility is breathed, among trails, rivers and viewpoints, lots of flora, fauna, 1 hour from the city.

Home in Panamá
5 out of 5 average rating, 3 reviews

Villa la Vista - majestic mountain hideaway

Relax and unwind in this stunning private hideaway in Altos Cerro Azul, just 40 minutes from Tocumen Airport. Leave the world behind with breathtaking views of the city, Pacific Ocean, and Lago Alajuela and arresting sunsets. Stylishly decorated, this home has three bedrooms with two king sized beds and a queen to comfortably accommodate 6 people. Pool, jacuzzi, bbq, Wifi, TV and ample parking for your family or romantic getaway. Melt into another world in this tropical oasis!

Guest favorite
Cabin in Panamá
4.93 out of 5 average rating, 87 reviews

The Crystal House: Luxury Modern Wood Cabin

Crea recuerdos inolvidables en este alojamiento único e ideal para familias. Quédate en una cabaña en medio del Parque Nacional Chagres a 50 minutos de la ciudad. Podrás estar en contacto con la naturaleza contando con todas las comodidades de un alojamiento de lujo. Con una de las mejores vistas a la ciudad puedes disfrutar de una buena barbacoa, una siesta en la hamaca o una reunión alrededor de la chimenea. Relájate y conéctate con el lindo verde de Panamá. Te esperamos!

Top guest favorite
Boat in Guna Yala Comarca
5 out of 5 average rating, 6 reviews

Private Caribbean Boat Retreat, San Blas Islands

Step aboard your own private floating villa in San Blas — no crowds, no shared spaces, just your group and one of the most untouched corners of the Caribbean. This is not a tour. It’s a fully private experience with a dedicated crew, optional chef service, and a completely customizable itinerary designed around you. Wake up surrounded by turquoise waters, explore deserted islands, snorkel vibrant reefs, or simply relax on deck with nothing but the ocean around you.

Guest favorite
Boat in San Blas Islands
5 out of 5 average rating, 17 reviews

San Blas: sail, sleep and wake up on paradise

Welcome aboard! We invite you to embark on a unique experience, delving deep into the Guna Yala natural and indigenous reserve with all the luxury and comfort that only our 57-foot Lagoon “Nomad” can offer. We are experienced sailors, lovers of adventure and nature, and we are also prepared to provide you with premium quality service. We will take care of every detail so you can have the best vacation of your life and return home with many stories to tell!

Cabin in Cayos Chichime
4.69 out of 5 average rating, 29 reviews

An-Dutu Boutique Cabins

Welcome to An-Dutu Boutique Cabin, an exclusive experience in the heart of San Blas. Our cabin is the only one in the entire area with air conditioning, designed for those who wish to experience the natural beauty of the archipelago without compromising on comfort. Designed to accommodate up to 4 people, An-Dutu combines the rustic charm of the islands with carefully selected details for a comfortable, private, and memorable stay."

Popular amenities for Isla Iguana, Guna Yala, Panamá vacation rentals