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Guesthouse vacation rentals in Irvine

Find and book unique guesthouse rentals on Airbnb

Top-rated guesthouse rentals in Irvine

Guests agree: these guesthouse rentals are highly rated for location, cleanliness, and more.

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Top guest favorite
Guesthouse in Santa Ana
4.97 out of 5 average rating, 200 reviews

Cozy 2-bedroom private guesthouse near South Coast

Step into this getaway house, away from all the hustle and bustle of daily life. You will find calmness and peace on your vacation. Indulge in a hot cup of coffee under the patio in a quiet environment or make your family a hot breakfast in the new kitchen before you head out to nearby attractions. Just bring your sun glasses and luggages. 5 minutes from South Coast Plaza. 25 Minutes from Disneyland Park. 20 minutes from all beautiful beaches, shopping centers and top restaurants of the region.

Guest favorite
A detached guest house is surrounded by a landscaped yard featuring various succulents and palm trees. A tall, textured wall provides privacy, while large windows reflect natural light. The outdoor area is paved and includes a small seating arrangement, creating a welcoming outdoor space.
Guesthouse in Eastside Costa Mesa
4.91 out of 5 average rating, 520 reviews

Eastside Casita

Located 1/2 mile from Newport Beach and walking distance to a variety of restaurants, cafes, bars, and stores it is great home base for exploring the Newport Beach and Costa Mesa area and is just 2 miles from the water! Guest house is detached from main house, has private entrance, parking, full kitchen and fenced off back yard space. The Patio includes a BBQ and patio table to enjoy So-Cal evenings or take in the sun while not out exploring. Accommodating for both adventure and work travel!

Top guest favorite
A spacious living area is showcased, featuring a white sofa adorned with yellow accent pillows. A warm brown lounge chair complements the neutral decor. A round mirror reflects natural light, while a small plant adds a touch of greenery to the welcoming atmosphere.
Guesthouse in Costa Mesa
4.96 out of 5 average rating, 286 reviews

Sunny Days - A Bright and Cheerful Guesthouse

Sunny Days is a beautiful and spacious 600 sq. ft. studio apartment with a private entrance and patio. You'll love the bright and airy space, complete with 10-foot ceilings! In the evenings, relax with a glass of wine in the cozy private patio, grilling dinner on the BBQ, and hanging around the gas fire pit. We are centrally located to Newport Beach, John Wayne Airport, and Disneyland. Only a short walk to TeWinkle Park and the OC Fairgrounds. Easy free street parking in a lovely neighborhood.

Top guest favorite
A warm fire pit is surrounded by dark pebbles, with flames dancing above. Two elegant champagne glasses are positioned nearby, alongside a bottle of sparkling wine adorned with floral designs. The outdoor setting is complemented by lush greenery in the background.
Guesthouse in Trabuco Canyon
4.98 out of 5 average rating, 118 reviews

Farmhouse - 360° Nature Views in Trabuco Canyon

Escape to tranquility in Trabuco Canyon, CA. This fully-renovated two-bedroom, one-bath retreat offers a full kitchen, large patio with propane grill, fire pit, Adirondack chairs, and a laundry room. Surrounded by nature, it’s located on a working farm with chickens and fruit trees. Walk to the historic Cook's Corner Bar, enjoy breathtaking hiking trails, scenic drives, & beautiful restaurants - even a local winery. Guests have full access to the house and patio. Book your nature retreat today!

Top guest favorite
A comfortable living area features a light-colored sofa adorned with decorative pillows. A medium-sized television is positioned on a sleek wooden console. Large windows allow natural light to fill the space, offering views of surrounding greenery, while a wooden coffee table rests in front.
Guesthouse in Santa Ana
4.95 out of 5 average rating, 1,408 reviews

Quiet Peaceful Studio

Private studio apartment. Second-story unit, set back from the street, in a separate building behind the hosts' home. Located in a beautiful historic neighborhood, on a quiet street shaded by oak trees. Disneyland and the Anaheim Convention Center are only 10 minutes away. The Honda Center and Anaheim Stadium 5 minutes. The beaches are an easy 20 minute drive. Excellent restaurants and shopping are abundant. Close to Old Town Orange, Chapman University, and the Santa Artists Village.

Top guest favorite
A charming cottage exterior is shown, featuring a welcoming red door framed by two windows. A stone path leads to the entrance, surrounded by a gravel area and lush green grass. Nearby, natural landscaping includes trees and a wooden fence.
Guesthouse in Trabuco Canyon
4.97 out of 5 average rating, 148 reviews

Orange County Country Cottage

Get out of the city and come spend a night in this relaxing 1 bedroom cottage in the hills of Orange County's Trabuco Canyon. Our little cabin has a queen bed, couch, small table & chairs for dining, bathroom with shower, small kitchenette with microwave, refrigerator, & Keurig coffee maker. Hike right out of the backyard to miles of trails with beautiful mountain views, wildlife, seasonal creeks or 2 of OC's best kept secrets for dinner Rose Canyon Cantina & Trabuco Oaks Steakhouse.

Top guest favorite
The living area features a comfortable tan leather sofa paired with a woven storage ottoman. Natural light pours in through expansive sliding doors, leading to a private patio. A staircase with a black railing elegantly ascends beside the textured gray wall.
Guesthouse in Santa Ana
4.99 out of 5 average rating, 258 reviews

D'Loft By JC

D'Loft is newly built in July 2023. Your family will be close to everything when you stay at this centrally-located place. We are located 10-15 Min from Disneyland, the beach, shopping and much more! D'Loft features an open concept design, dressed in high end appliances and it's own private patio. Relax in a comfy Cal King Bed in addition to a queen size sofa bed + a twin sleeper, available at your disposal. Open the double sliders and make indoor outdoor space!

Top guest favorite
A welcoming living area features a soft beige sofa, a wooden coffee table, and a light wood dining table surrounded by four chairs. Natural light enters through a door and window, highlighting a ceiling fan and art piece on the wall.
Guesthouse in Corona del Mar
4.97 out of 5 average rating, 316 reviews

Charming 2 br condo nr. beach

Completely remodeled beach close apartment in best neighborhood in Newport. Walk to shops, restaurants & beach. Bikes available for exploring the area. Professionally decorated, brand new kitchen, bath, beds, patio. Quiet kids over 5 years old are welcome. Pets welcomed - see notes on pet's in House Rules section below. Come and enjoy! Our City of Newport Beach lodging permit # is SLP11906. Ten % of the fee goes to the Transient Occupancy Tax (TOT).

Top guest favorite
Guesthouse in Orange
4.93 out of 5 average rating, 430 reviews

Studio Near Disneyland With King Bed

Large remodeled Studio near Disneyland & Anaheim Convention Center, Anaheim Honda Center/Stadium, UCI Medical Center, Chapman University, Orange circle. A very high end Serta CalKing size bed. Full kitchen. Private bathroom. Easy access to freeways. Closed to Target, restaurants, In and out bugert and super market. Nice and quiet neighborhood. Free parking. Watch 4th of July fireworks from your suite. Two nights minimum.

Top guest favorite
Guesthouse in Santa Ana
4.9 out of 5 average rating, 177 reviews

Minimalist Modern House

1bed, 1bath, kitchen & living room. 1 gated parking space. For security purposes, the address in Santa Ana is proximate. Exact address in Garden Grove (2.0 miles away) will be sent after booking confirmed. Tesla level 2 charger is available as $25/day/car. The third guest fee is $35/night (sofa bed is available) Sauna self service is available is available at $30 for 2 hours. Please let us know if you need.

Guest favorite
The exterior of the beach cottage features a private entrance with a white door framed by windows. A picnic table is situated under a teal umbrella in the outdoor area, surrounded by concrete and greenery. A pathway leads to the entrance, enhancing accessibility.
Guesthouse in Huntington Beach
4.85 out of 5 average rating, 148 reviews

Cottage Beach guest house

This is a back house of the duplex, there is 2 houses on the property , each house has own yard, no sharing wall . It is a separate structure, back house by alley , convenience parking, easy access . Make some memories at this unique and family-friendly place. Lexus US Open of Surfing, July 25 - Aug 2, 2026.

Top guest favorite
A serene swimming pool is bordered by a stone pathway, with lush greenery surrounding it. A friendly white dog stands near the edge of the pool, and potted plants add a touch of color to the tranquil outdoor setting.
Guesthouse in Eastside Costa Mesa
4.96 out of 5 average rating, 914 reviews

Poolhouse studio

Your own private entrance to our charming detached studio located on the other side of the pool from the main house in our backyard. Relaxing decor, comfortable Queen size bed, full Futon available as well upon request. Private bath with (website hidden), WiFi, mini-fridge, Fans, AC

Popular amenities for Irvine guesthouse rentals

When is the best time to visit Irvine?

MonthJanFebMarAprMayJunJulAugSepOctNovDec
Avg. priceG$28,238 GYDG$29,074 GYDG$30,329 GYDG$23,636 GYDG$27,610 GYDG$28,238 GYDG$28,238 GYDG$28,028 GYDG$27,401 GYDG$28,656 GYDG$28,238 GYDG$29,283 GYD
Avg. temp14°C14°C16°C17°C19°C20°C23°C24°C23°C20°C17°C14°C

Quick stats about guesthouse rentals in Irvine

  • Total vacation rentals

    Explore 30 vacation rentals in Irvine

  • Nightly prices starting at

    Irvine vacation rentals start at G$16,733 GYD per night before taxes and fees

  • Verified guest reviews

    Over 2,530 verified reviews to help you choose

  • Vacation rentals with a pool

    10 properties feature pools

  • Rentals with dedicated workspaces

    20 properties have a dedicated workspace

  • Wi-Fi availability

    30 of Irvine vacation rentals include wi-fi access

  • Popular amenities for guests

    Guests love Kitchen, Wifi, and Pool across Irvine rentals

  • 4.9 Average rating

    Irvine stays are highly rated by guests—averaging 4.9 out of 5!

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