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Vacation rentals in Gulf of Guna Yala

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Top-rated vacation rentals in Gulf of Guna Yala

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Guest favorite
The space features large glass panels and wooden frames, creating a connection to the surrounding nature. Light filters through sheer curtains, illuminating the interior. Lush greenery is visible outside, enhancing the serene atmosphere of this intimate retreat.
Hut in Altos de Cerro azul
4.88 out of 5 average rating, 24 reviews

Rest and Wellness Retreat |Altos de Cerro Azul

✨ Escape to the Rest you deserve in Altos de Cerro Azul ✨ This is not just another accommodation: it is an experience of comfort and an intimate atmosphere of well-being, in a cabin designed to connect and return to you 🫸💛🫷 Relax in a private atmosphere, surrounded by nature, perfect mountain climate to recharge, disconnect and enjoy natural peace, with terrace and intimate garden, just for you. Just 50 minutes from the airport, your ideal retreat for rest, well-being and natural connection.

Top guest favorite
Cottage in Panamá
4.92 out of 5 average rating, 110 reviews

Round House River Dreams Cerro Azul

Get away from it all and relax in an idyllic tropical rustic retreat set beside a beautiful river with small cascades in the mountains of Cerro Azul. This spacious 2-story, one bedroom home is ideal for couples, small families or groups, with ample space to sleep 6 to 7 people. The property lies within Charges National Park with all its tropical flora and fauna, blue butterflies, hummingbirds, waterfalls and walking trails at your doorstep. Come experience this unique vacation home destination.

Top guest favorite
Boat in San Blas Islands
5 out of 5 average rating, 7 reviews

Private Catamaran live on board

Welcome aboard catamaran Yoyo, your floating home in the San Blas Islands. Your stay includes breakfast and snacks, with an optional meals and drinks package for USD 80 per person per day. For stays of 5 or more days, meals and drinks are included. Spend your days swimming, snorkeling, fishing, exploring hidden beaches, or relaxing on deck, and your nights unwinding under the stars. Experience the perfect blend of adventure, freedom, and laid-back island living with all the comfort you need.

Superhost
An aerial view captures the lush greenery of Narasgandub Island, surrounded by vibrant turquoise waters. The shoreline features a sandy beach bordered by palm trees, creating a tranquil atmosphere. The clear ocean extends into the horizon, highlighting the island's secluded paradise appeal.
Hut in San Blas
4.8 out of 5 average rating, 137 reviews

Bliss in the San Blas Islands

Discover Panama's best-kept secret in San Blas Islands, a set of 365 Caribbean Islands for 365 days of sun. All the Islands are owned by natives, "The Gunas," who will be very keen to welcome you and share their culture. Enjoy our crystal clear water, beautiful sunshine, and white sand, and wake up in the morning to hear the waves of the Ocean and see spectacular scenery from your room. A well-hidden Paradise awaits you in this unforgettable trip that will give you memories for a lifetime.

Guest favorite
A private hot tub sits at the edge of a tranquil lake, surrounded by lush greenery. The serene water reflects the clear blue sky, while the distant hills provide a peaceful backdrop. The tub's blue tiles contrast with the natural landscape.
Cabin in Panama City
4.95 out of 5 average rating, 57 reviews

#1 Cabin on the Lake Cerro Azul

Escape to the tranquil beauty of Cerro Azul, Panama and stay in our cozy lakeside cabin. With breathtaking views of the surrounding mountains and direct access to the lake, this is the perfect retreat for nature lovers. Enjoy fishing, kayaking, or simply relax on the private dock and soak in the serenity of the surroundings. Our fully equipped cabin has everything you need for a comfortable stay, including a full kitchen, comfortable bedroom, and a spacious balcony with panoramic views.

Superhost
Cabin in Panama City
4.77 out of 5 average rating, 105 reviews

Altos Cerro Azul Panama Family Mountain House

Imagine waking up to birdsong, feeling the living energy of the mountain and a peace that fills the soul. In this Mountain Family House you will live unique experiences, with cool weather all year round, panoramic views, flowing rivers, waterfalls and trails that invite adventure and calm. Ideal for families and couples looking to disconnect from noise and reconnect with nature. Located in Los Altos de Cerro Azul, in the Chagres National Park, this oasis invites you to relax.

Guest favorite
Cabin in Panamá
4.92 out of 5 average rating, 79 reviews

The Crystal House: Luxury Modern Wood Cabin

Crea recuerdos inolvidables en este alojamiento único e ideal para familias. Quédate en una cabaña en medio del Parque Nacional Chagres a 50 minutos de la ciudad. Podrás estar en contacto con la naturaleza contando con todas las comodidades de un alojamiento de lujo. Con una de las mejores vistas a la ciudad puedes disfrutar de una buena barbacoa, una siesta en la hamaca o una reunión alrededor de la chimenea. Relájate y conéctate con el lindo verde de Panamá. Te esperamos!

Guest favorite
Two overwater cabins are nestled among palm trees, elevated above serene waters. A sandy beach is visible in the background, creating a tranquil atmosphere. The sky is mostly clear with soft clouds, reflecting the peaceful island setting.
Hut in Panamá
4.93 out of 5 average rating, 14 reviews

Overwater Cabin#1 on Misdub: Meals & Tour included

🛖 Overwater Cabin 👥 Minimum 2 guests or $20 extra fee per night for solo travelers. Capacity 2 guests, book a second cabin if needed. Welcome to Misdub Island, the sister island of Yani Island, nestled in the Lemon Keys. This secluded paradise is surrounded by pristine turquoise waters, offering unparalleled exclusivity and tranquility far from the crowds of day tours. ⚠️ Important note: Additional charges may apply if the pick-up location is off-route.

Top guest favorite
A cozy cabin features a spacious circular bed with striped bedding and a soft blue towel folded on top. Natural light enters through a skylight above, complementing the warm wooden accents and light-colored walls. A small seating area is visible to the side.
Boat in San Blas Islands
5 out of 5 average rating, 16 reviews

San Blas: sail, sleep and wake up on paradise

Welcome aboard! We invite you to embark on a unique experience, delving deep into the Guna Yala natural and indigenous reserve with all the luxury and comfort that only our 57-foot Lagoon “Nomad” can offer. We are experienced sailors, lovers of adventure and nature, and we are also prepared to provide you with premium quality service. We will take care of every detail so you can have the best vacation of your life and return home with many stories to tell!

Superhost
Cottage in Panamá
4.83 out of 5 average rating, 86 reviews

Altos de Cerro Azul | AC, Full Kitchen, 2 Rooms

Some escapes stay with you. This is one of them. Located in the highlands of Altos de Cerro Azul, this modern mountain home is perfect for disconnecting without giving up comfort. Wake up to panoramic views, breathe cooler air, and enjoy true peace. Ideal for couples, small families, or remote workers seeking a calm retreat in nature. Traveling as a couple? Ask us about a special rate. No pets allowed.

Superhost
Hut in Mamartupo
4.76 out of 5 average rating, 84 reviews

Ancestral Serenity: Life in an Indigenous Cabin

Welcome to the Guna Yala archipelago, a truly captivating place. The 365 islands that make it up are a haven of biodiversity and rich indigenous culture. If you love nature, diving, or just relaxing to the sound of the waves, Guna Yala is an ideal destination. You can also explore the traditional cabins and taste the local cuisine, which is a reflection of the rich cultural heritage of the region.

Top guest favorite
Home in Panama City
5 out of 5 average rating, 13 reviews

Casa del Lago 2025

New lakefront house in Cerro Azul, decorated by a D&G architect with furniture brought from Bali. It has 3 bedrooms, 3 bathrooms and 4 double beds, equipped kitchen, BBQ, air conditioning and hot water. Cook a delicious BBQ with your friends in front of the lake and enjoy the sunsets from an unparalleled view with direct access and kayak included.

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