House vacation rentals in Cherokee County

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Top-rated house rentals in Cherokee County

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Guest favorite

Home in Chesnee

4.89 out of 5 average rating, 47 reviews

Carolina Cottage, 1940s nostalgia, firepit & patio

As seen in Cottages & Bungalows Magazine, Relax in this charming 1940's Cottage in laid back Chesnee, SC just 4 blocks from Historic Downtown. Newly renovated by Brittany Smith of Thorn Cove Abode, only 17 minutes from downtown Spartanburg, 34 minutes to Landrum, 40 minutes to Tryon NC, 45 minutes from Greenville. Enjoy a staycation on the patio by day and fire pit by night or visit our National Historic Battlefield, beautiful hiking trails (on SC and NC side) and great thrifting/ antique shops.

Superhost

Home in Cowpens

4.4 out of 5 average rating, 53 reviews

Large home with vintage appeal

This Small town home has a vintage appeal and is convenient to so many things. It’s almost 2500 sq. ft. and close to Lake Blalock and Bowen. Close to several colleges like Limestone, Converse, Wofford, Spartanburg Methodist, and USC Upstate. It’s close to I-85 which will take you to Charlotte 78 miles away and Greenville 48 miles. It’s minutes from the Gaffney outlet mall. It would be a great place for out of town guest if you’re having a wedding or visiting Spartanburg for an event or business

Home in Smyrna

5 out of 5 average rating, 8 reviews

Getaway to the southern pines on 52 acres!

Spacious and serene country setting with 4 large bedrooms, 2 baths. Living room next to kitchen for waiting on that special meal to be ready and huge game room for movies and computer. Plenty of room for 4 couples and an extra twin bed in the game room! Keep a peek out the window for the wild dear in the evenings or the wild turkeys in the morning mist. 1 hour drive from Tryon Equestrian Ctr, 45 min to Charlotte,and 30 min to Gaffney. Visit the area hard cider, apple donuts and harvest mazes.

Guest favorite

Home in Blacksburg

4.82 out of 5 average rating, 39 reviews

Cozy - 3 Bed room home with an indoor fireplace

Relax with the whole family at this peaceful 2 story place to stay. Located right beside the Broad river in the mill hill village and just a short 10 miles from limestone college and 20 miles from Gardner web, you can bring your kayaks and explore the various boat landing points up and down the river or you can go out to the various national trails in the area. You can also take a short 16 mile drive to the new near by casino. This is the perfect little get away for what ever your plans are.

Guest favorite

Home in Spartanburg

4.92 out of 5 average rating, 333 reviews

beautiful nature,3bedroom, 2 king and 2 queen beds

Our home is located in beautiful neighborhood. We love our view. House has 3 bedrooms ( two bedrooms have king beds and one bedroom has two queen beds), also have two futons in living room that can be used as full size beds. This home was remodeled by my husband and me and were constantly adding new ideas to it. however, we do not tolerate any kind of wild parties that include hard liquor or smoking. absolutely no smoking in the house the wood in house will peneteate the smell.

Guest favorite

Home in Spartanburg

5 out of 5 average rating, 15 reviews

Madelyn’s Manor

Welcome to Madelyn’s Manor, your minimalist retreat! This modern, thoughtfully designed space offers clean lines, cozy simplicity, and all the essentials for a relaxing stay. Enjoy the peace of mind of a non-toxic environment, meticulously cleaned with natural products. Conveniently located near a golf course, a hospital, and local attractions, it’s the perfect base for exploring or unwinding. Experience effortless comfort and eco-friendly style in a space that feels like home.

Superhost

Home in Cowpens

5 out of 5 average rating, 11 reviews

Home in Cowpens off exit 83

This nice fully renovated brick home is right off HWY 85 exit 83. It has 3 bedrooms with 2 full bathrooms. There is a full-size washer, dryer and a fully furnished kitchen with all the essentials needed to cook with. The master room has a king bed with a 40" smart TV. Second room has a queen bed with a 40" smart TV. The third room has a queen bed with an office desk for your working area. This home is located 7 miles from The Gaffney outlet, 10 miles from Spartanburg downtown.

Guest favorite

Home in Pacolet

4.94 out of 5 average rating, 64 reviews

Quiet, Convenient, Cozy Home!

Beautiful, peaceful AND spacious? Look no further! A true home away from home. Featuring a new 6 foot privacy fence so you can relax on the deck overlooking the pond or let the doggos run free. Screened in patio, outdoor firepit, and an additional downstairs lounge area in the backyard. 12 minutes to downtown Spartanburg. Convenient drive to USC Upstate, Wofford, and SMC. 30-45 minutes to Greenville. Plenty of driveway space to accommodate multiple cars or a trailer.

Guest favorite

Home in Spartanburg

4.9 out of 5 average rating, 41 reviews

Family/pet-friendly with ACRES of outdoor space!

You have found the perfect spot for your get away or extended stay in Spartanburg. “House of Blues” comfortably sleeps 8 guests and is pet & family-friendly! You’ll find yourself less than 15 minutes from downtown Spartanburg, and less than 5 minutes to great shopping, dining, and entertainment on East Main Street, as well as easy access to Interstate 85. Amenities include ample outdoor space with a large lawn, picnic table, and grill!

Superhost

Home in Spartanburg

4.67 out of 5 average rating, 6 reviews

Cozy Home one block from The Creek Golf Club

Welcome to Cozy Home! Our newly renovated 3-bedroom, 2-bathroom home is your perfect home away from home. This modern space features brand new kitchen appliances, a washer and dryer, high-speed internet, bathroom essentials, and a fully stocked kitchen. The open floor plan offers a clean, spacious, and stylish environment. Conveniently located near major highways, shopping centers, and a variety of dining options.

Top guest favorite

Home in Gaffney

5 out of 5 average rating, 19 reviews

Cottage On College

Discover the charm of the “Cottage on College Drive,” a cozy haven nestled on Historic College Drive in Gaffney, South Carolina. This beautifully appointed cottage offers the perfect blend of comfort, convenience, and tranquility—ideal for solo travelers, couples, or small families eager to explore the Upstate. Steps from Limestone University & downtown Gaffney’s restaurants, shops, and attractions.

Guest favorite

Home in Gaffney

4.94 out of 5 average rating, 94 reviews

Cozy 2 bedroom home near downtown Gaffney.

Truly live like a local at Casita Gaffney! This cozy modern home sleeps up to 6 guests. Situated near the heart of Gaffney, our home is your relaxation destination. Conveniently located only minutes from I-85. Stocked kitchen for cooking and professionally cleaned. Our casa es su casa! This retreat is the ideal getaway for couples, friends, and small families to explore everything Gaffney.